Acute and repeated-doses (28 days) toxicity study of Hypericum polyanthemum Klotzsch ex Reichardt (Guttiferare) in mice

Food and Chemical Toxicology

Volumn 50, Issue 7, 2012, Pages 2349-2355

  Betti, Andresa Heemann ^a   Stein, Ana Cristina ^a   Dallegrave, Eliane ^b   Wouters, Angelica Terezinha Barth ^a   Watanabe, Tatiane Terumi Negrão ^a   Driemeier, Davi ^a   Buffon, Andréia ^a   Rates, Stela Maris Kuze ^a  

^a FEDERAL UNIVERSITY OF RIO GRANDE DO SUL   (Brazil)

^b FEPPS   (Brazil)

Author keywords

Acute oral toxicity; Hypericum polyanthemum; Repeated dose toxicity

Indexed keywords

ALANINE AMINOTRANSFERASE; ALKALINE PHOSPHATASE; ASPARTATE AMINOTRANSFERASE; CREATININE; CYCLOHEXANE; HEMOGLOBIN; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; HYPERICUM POLYANTHEMUM EXTRACT; LOW DENSITY LIPOPROTEIN CHOLESTEROL; PHOSPHOTRANSFERASE; PLANT EXTRACT; TRIACYLGLYCEROL; UNCLASSIFIED DRUG; URIC ACID;

ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BIOCHEMICAL COMPOSITION; CHOLESTEROL BLOOD LEVEL; CONTROLLED STUDY; DRUG MEGADOSE; EOSINOPHIL COUNT; ERYTHROCYTE COUNT; HEMATOCRIT; HEMATOLOGICAL PARAMETERS; HISTOPATHOLOGY; HYPERICUM; HYPERICUM POLYANTHEMUM; LIVER HISTOLOGY; MALE; MEAN CORPUSCULAR HEMOGLOBIN; MEAN CORPUSCULAR VOLUME; MONOCYTE; MORTALITY; MOUSE; NEUTROPHIL COUNT; NONHUMAN; ORGAN WEIGHT; REPEATED DRUG DOSE; SINGLE DRUG DOSE; THROMBOCYTE COUNT; TOXICITY TESTING; WEIGHT GAIN;

ANIMALS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DOSE-RESPONSE RELATIONSHIP, DRUG; FEEDING BEHAVIOR; HYPERICUM; MALE; MICE; ORGAN SIZE; PLANT EXTRACTS; TOXICITY TESTS, ACUTE; WEIGHT GAIN;

ANIMALIA; HYPERICUM; HYPERICUM POLYANTHEMUM; MUS; RODENTIA;

EID: 84861430742     PISSN: 02786915     EISSN: 18736351     Source Type: Journal    
DOI: 10.1016/j.fct.2012.04.012     Document Type: Article

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