Synthesis and the intestinal glucosidase inhibitory activity of 2-aminoresorcinol derivatives toward an investigation of its binding site

Bioscience, Biotechnology and Biochemistry

Volumn 76, Issue 5, 2012, Pages 1044-1046

  Kato, Eisuke ^a   Oikawa, Kenichi ^a   Takahashi, Keisuke ^a   Kawabata, Jun ^a  

^a HOKKAIDO UNIVERSITY   (Japan)

Author keywords

Diabetes mellitus; Glucosidase inhibitor; Structure activity relationship; Uncompetitive inhibition

Indexed keywords

AROMATIC RINGS; CARBONYL GROUPS; DIABETES MELLITUS; GLUCOSIDASE; INHIBITION MECHANISMS; INHIBITORY ACTIVITY; MOLECULAR PROBES; PHENOLIC HYDROXYL GROUP; STRUCTURAL CHANGE; STRUCTURE ACTIVITY RELATIONSHIPS;

ALKYLATION;

PHENOLS;

ALPHA GLUCOSIDASE; ANTIDIABETIC AGENT; ENZYME INHIBITOR; RESORCINOL DERIVATIVE; SUCRASE;

ARTICLE; BINDING SITE; CHEMISTRY; DRUG ANTAGONISM; DRUG DESIGN; ENZYMOLOGY; HUMAN; INTESTINE; MOLECULAR PROBE; STRUCTURE ACTIVITY RELATION; SYNTHESIS;

ALPHA-GLUCOSIDASES; BINDING SITES; DRUG DESIGN; ENZYME INHIBITORS; HUMANS; HYPOGLYCEMIC AGENTS; INTESTINES; MOLECULAR PROBES; RESORCINOLS; STRUCTURE-ACTIVITY RELATIONSHIP; SUCRASE;

EID: 84861430374     PISSN: 09168451     EISSN: 13476947     Source Type: Journal    
DOI: 10.1271/bbb.120009     Document Type: Article

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