The role of clinically significant venous thromboembolism and thromboprophylaxis in pediatric patients with pelvic or femoral fractures

Journal of Pediatric Orthopaedics

Volumn 32, Issue 4, 2012, Pages 357-361

  Greenwald, Lark J ^a   Yost, Mary Teresa ^a   Sponseller, Paul D ^a   Abdullah, Fizan ^a   Ziegfeld, Susan M ^a   Ain, Michael C ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Deep venous thrombosis; Pediatric; Pulmonary embolism; Thromboprophylaxis; Trauma

Indexed keywords

ENOXAPARIN; HEPARIN; WARFARIN;

ADOLESCENT; ARTICLE; CENTRAL VENOUS CATHETERIZATION; CHILD; CHILDHOOD INJURY; DEEP VEIN THROMBOSIS; DISEASE PREDISPOSITION; FEMALE; FEMUR FRACTURE; HUMAN; LUNG EMBOLISM; MAJOR CLINICAL STUDY; MALE; MEDICAL RECORD REVIEW; MORTALITY; PELVIS FRACTURE; PRESCHOOL CHILD; PRIORITY JOURNAL; PROGNOSIS; SCHOOL CHILD; THROMBOSIS PREVENTION; VENOUS THROMBOEMBOLISM;

ADOLESCENT; AGE FACTORS; ANTICOAGULANTS; CATHETERIZATION, CENTRAL VENOUS; CHILD; CHILD, PRESCHOOL; FEMALE; FEMORAL FRACTURES; FRACTURES, BONE; HUMANS; MALE; PELVIC BONES; PREVALENCE; RETROSPECTIVE STUDIES; RISK FACTORS; VENOUS THROMBOEMBOLISM;

EID: 84861417214     PISSN: 02716798     EISSN: 15392570     Source Type: Journal    
DOI: 10.1097/BPO.0b013e31824b2a07     Document Type: Article

References (21)

1. Shackford SR, Moser KM. Deep venous thrombosis and pulmonary embolism in trauma patients. J Intensive Care Med. 1988;3:87-98.
2. O'Malley KF, Ross SE. Pulmonary embolism in major trauma patients. J Trauma. 1990;30:748-750.
3. Britt LD, Zolfaghari D, Kennedy E, et al. Incidence and prophylaxis of deep vein thrombosis in a high risk trauma population. Am J Surg. 1996;172:13-14.
4. Geerts WH, Pineo GF, Heit JA, et al. Prevention of venous thromboembolism: the Seventh ACCP Conference on antithrom-botic and thrombolytic therapy. Chest. 2004;126:338S-400S.
5. Chan AK, Deveber G, Monagle P, et al. Venous thrombosis in children. J Thromb Haemost. 2003;1:1443-1455.
6. Kritsaneepaiboon S, Lee EY, Zurakowski D, et al. MDCT pulmonary angiography evaluation of pulmonary embolism in children. AJR Am J Roentgenol. 2009;192:1246-1252.
7. Sandoval JA, Sheehan MP, Stonerock CE, et al. Incidence, risk factors, and treatment patterns for deep venous thrombosis in hospitalized children: an increasing population at risk. J Vasc Surg. 2008;47:837-843.
8. Victoria T, Mong A, Altes T, et al. Evaluation of pulmonary embolism in a pediatric population with high clinical suspicion. Pediatr Radiol. 2009;39:35-41.
9. Buck JR, Connors RH, Coon WW, et al. Pulmonary embolism in children. J Pediatr Surg. 1981;16:385-391.
10. Azu MC, McCormack JE, Scriven RJ, et al. Venous thromboem-bolic events in pediatric trauma patients: is prophylaxis necessary? J Trauma. 2005;59:1345-1349.
11. Rohrer MJ, Cutler BS, MacDougall E, et al. A prospective study of the incidence of deep venous thrombosis in hospitalized children. J Vasc Surg. 1996;24:46-49; discussion 50.
12. Raffini L, Huang YS, Witmer C, et al. Dramatic increase in venous thromboembolism in children's hospitals in the United States from 2001 to 2007. Pediatrics. 2009;124:1001-1008.
13. Tavil B, Kuskonmaz B, Kiper N, et al. Pulmonary thromboemb-olism in childhood: a single-center experience from Turkey. Heart Lung. 2009;38:56-65.
14. Truitt AK, Sorrells DL, Halvorson E, et al. Pulmonary embolism: which pediatric trauma patients are at risk? J Pediatr Surg. 2005; 40:124-127.
15. Massicotte MP, Dix D, Monagle P, et al. Central venous catheter related thrombosis in children: analysis of the Canadian Registry of Venous Thromboembolic Complications. J Pediatr. 1998;133: 770-776.
16. Biss TT, Brandao LR, Kahr WH, et al. Clinical features and outcome of pulmonary embolism in children. Br J Haematol. 2008;142:808-818.
17. Andrew M, David M, Adams M, et al. Venous thromboembolic complications (VTE) in children: first analyses of the Canadian Registry of VTE. Blood. 1994;83:1251-1257.
18. Parasuraman S, Goldhaber SZ. Venous thromboembolism in children. Circulation. 2006;113:e12-e16.
19. Biss TT, Brandao LR, Kahr WHA, et al. Clinical probability score and D-dimer estimation lack utility in the diagnosis of childhood pulmonary embolism. J Thromb Haemost. 2009;7:1633-1638.
20. Nguyen LT, Laberge JM, Guttman FM, et al. Spontaneous deep vein thrombosis in childhood and adolescence. J Pediatr Surg. 1986;21:640-643.
21. Cavo M, Wang W, O'Brien SH. Use of low molecular weight heparin for thromboprophylaxis in a pediatric inpatient population: reasons for use and incidence of bleeding complications [letter]. Thromb Res. 2010;125:370-372.