Preischemic vagal efferent stimulation increases infarct size in rabbits;La estimulación vagal eferente preisquémica aumenta el tamaño del infarto de miocardio en conejos

Revista Argentina de Cardiologia

Volumn 80, Issue 1, 2012, Pages 7-13

  Buchholz, Bruno ^a,b   Siachoque, Nadezda ^a   Rodríguez, Manuel ^a,b   Ivalde, Flavio C ^a   Álvarez Yuseff, Marãa F ^a   Gelpi, Ricardo J ^a,b  

^a UNIVERSIDAD DE BUENOS AIRES   (Argentina)

^b SOCIEDAD ARGENTINA DE CARDIOLOGÍA   (Argentina)

Author keywords

Atenolol; Atropine; Esmolol; Myocardial infarction; Vagal stimulation

Indexed keywords

ATENOLOL; ATROPINE; ESMOLOL;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CHOLINERGIC SYSTEM; CONTROLLED STUDY; EXPERIMENTAL RABBIT; HEART INFARCTION; HEART INFARCTION SIZE; HEART MUSCLE ISCHEMIA; NONHUMAN; REPERFUSION INJURY; VAGUS NERVE STIMULATION;

EID: 84861412633     PISSN: 00347000     EISSN: 18503748     Source Type: Journal    
DOI: None     Document Type: Article

References (16)

1. Jessup M, Arozena S. Heart failure. N Engl J Med 2003;348:2007-2018.
2. Yellon DM, Downey JM. Preconditioning the myocardium: from cellular physiology to clinical cardiology. Physiol Rev 2003;83:1113-1151.
3. Critz ST, Cohen MV, Downey JM. Mechanisms of acetylcholine and bradykinin induced preconditioning. Vascul Pharmacol 2005;42:201-209.
4. Armour JA. Cardiac neuronal hierarchy in health and disease. Am J Physiol Regul Integr Comp Physiol 2004;287:262-271.
5. Levy MN. Sympathetic-parasympathetic interactions in the heart. Circ Res 1971;29:437-445.
6. Belevych AE, Sims C, Harvey RD. ACh-induced rebound stimulation of L-type Ca2+ current in guinea-pig ventricular myocytes, mediated by Gby-dependent activation of adenylyl cyclase. J Physiol 2001;536:677-692.
7. Kakinuma Y, Ando M, Kuwabara M, Katare RG, Okudela K, Kobayashi M, et al. Acetylcholine from vagal stimulation protects cardiomyocytes against ischemia and hypoxia involving additive non-hypoxic induction of HIF-1a. FEBS letters. 2005;579:2111-2118.
8. Yang XM, Krieg T, Cui L, Downey JM, Cohen MV. NECA and bradykinin at reperfusion reduce infarction in rabbit hearts by signaling through PI3K, ERK, and NO. J Mol Cell Cardiol 2004;36:411-421.
9. Zang WJ, Chen LN, Yu XJ. Progress in the study of vagal control of cardiac ventricles. Acta Physiologica Sinica 2005;57(6):659-672.
10. Herring N, Paterson DJ. Neuromodulators of peripheral cardiac sympatho-vagal balance. Exp Physiol 2009;94(1):46-53.
11. Feliciano L, Henning R. Vagal nerve stimulation releases vasoactive intestinal peptide which significantly increases coronary artery blood flow. Cardiovasc Res 1998;40:45-55.
12. Mioni Ch, Bazzani C, Giuliani D, Altavilla D, Leone S, Ferrari A, et al. Activation of an efferent cholinergic pathway produces strong protection against myocardial ischemia/reperfusion injury in rats. Crit Care Med 2005;33:2621-2628.
13. Zheng C, Li M, Inagaki M, Kawada T, Sunagawa K, Sugimachi M. Vagal stimulation markedly suppresses arrhythmias in conscious rats with chronic heart failure after myocardial infarction. Conf Proc IEEE. Eng Med Biol Soc 2005;7:7072-7125.
14. Ando M, Katare RG, Kakinuma Y, Zhang D, Yamasaki F, Muramoto K, et al. Efferent vagal nerve stimulation protects heart against ischemia-induced arrhythmias by preserving connexin43 protein. Circulation 2005;112:164-170.
15. Li M, Zheng C, Sato T, Kawada T, Sugimachi M, Sunagawa K. Vagal nerve stimulation markedly improves long-term survival after chronic heart failure in rats. Circulation 2004;109:120-124.
16. Groves DA, Brown VJ. Vagal nerve stimulation: a review of its applications and potential mechanisms that mediate its clinical effects. Neurosci Biobehav Rev 2005;29:493-500.