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Volumn 41, Issue 1, 2012, Pages 343-370

Metabolite recognition principles and molecular mechanisms underlying riboswitch function

Author keywords

Ligand binding pockets; Metal ions; NMR; RNA structure and folding; X ray crystallography

Indexed keywords

RIBOZYME;

EID: 84861405805     PISSN: 1936122X     EISSN: 19361238     Source Type: Book Series    
DOI: 10.1146/annurev-biophys-101211-113224     Document Type: Review
Times cited : (134)

References (136)
  • 2
    • 74649084566 scopus 로고    scopus 로고
    • The ligand-free state of the TPP riboswitch: A partially folded RNA structure
    • Ali M, Lipfert J, Seifert S, Herschlag D, Doniach S. 2010. The ligand-free state of the TPP riboswitch: a partially folded RNA structure. J. Mol. Biol. 396:153-65
    • (2010) J. Mol. Biol. , vol.396 , pp. 153-165
    • Ali, M.1    Lipfert, J.2    Seifert, S.3    Herschlag, D.4    Doniach, S.5
  • 3
    • 85011940614 scopus 로고    scopus 로고
    • Bacterial aptamers that selectively bind glutamine
    • Ames TD, Breaker RR. 2011. Bacterial aptamers that selectively bind glutamine. RNA Biol. 8:82-89
    • (2011) RNA Biol. , vol.8 , pp. 82-89
    • Ames, T.D.1    Breaker, R.R.2
  • 4
    • 77955437093 scopus 로고    scopus 로고
    • A eubacterial riboswitch class that senses the coenzyme tetrahydrofolate
    • Ames TD, Rodionov DA, Weinberg Z, Breaker RR. 2010. A eubacterial riboswitch class that senses the coenzyme tetrahydrofolate. Chem. Biol. 17:681-85
    • (2010) Chem. Biol. , vol.17 , pp. 681-685
    • Ames, T.D.1    Rodionov, D.A.2    Weinberg, Z.3    Breaker, R.R.4
  • 5
    • 77149165421 scopus 로고    scopus 로고
    • Idiosyncratically tuned switching behavior of riboswitch aptamer domains revealed by comparative small-angle X-ray scattering analysis
    • Baird NJ, Ferre-D'Amare AR. 2010. Idiosyncratically tuned switching behavior of riboswitch aptamer domains revealed by comparative small-angle X-ray scattering analysis. RNA 16:598-609
    • (2010) RNA , vol.16 , pp. 598-609
    • Baird, N.J.1    Ferre-D'Amare, A.R.2
  • 7
    • 9244225713 scopus 로고    scopus 로고
    • Structure of a natural guanine-responsive riboswitch com-plexed with the metabolite hypoxanthine
    • Batey RT, Gilbert SD, Montange RK. 2004. Structure of a natural guanine-responsive riboswitch com-plexed with the metabolite hypoxanthine. Nature 432:411-15
    • (2004) Nature , vol.432 , pp. 411-415
    • Batey, R.T.1    Gilbert, S.D.2    Montange, R.K.3
  • 8
    • 53149095767 scopus 로고    scopus 로고
    • Switching the light on plant riboswitches
    • Bocobza SE, Aharoni A. 2008. Switching the light on plant riboswitches. Trends Plant Sci. 13:526-33
    • (2008) Trends Plant Sci. , vol.13 , pp. 526-533
    • Bocobza, S.E.1    Aharoni, A.2
  • 9
    • 70350340728 scopus 로고    scopus 로고
    • The role of dynamic conformational ensembles in biomolec-ular recognition
    • Boehr DD, Nussinov R, Wright PE. 2009. The role of dynamic conformational ensembles in biomolec-ular recognition. Nat. Chem. Biol. 5:789-96
    • (2009) Nat. Chem. Biol. , vol.5 , pp. 789-796
    • Boehr, D.D.1    Nussinov, R.2    Wright, P.E.3
  • 10
    • 77749304812 scopus 로고    scopus 로고
    • Multivector fluorescence analysis of the xpt guanine riboswitch aptamer domain and the conformational role of guanine
    • Brenner MD, Scanlan MS, Nahas MK, Ha T, Silverman SK. 2010. Multivector fluorescence analysis of the xpt guanine riboswitch aptamer domain and the conformational role of guanine. Biochemistry 49:1596-605
    • (2010) Biochemistry , vol.49 , pp. 1596-1605
    • Brenner, M.D.1    Scanlan, M.S.2    Nahas, M.K.3    Ha, T.4    Silverman, S.K.5
  • 11
    • 35648974802 scopus 로고    scopus 로고
    • Time-resolved NMR methods resolving ligand-induced RNA folding at atomic resolution
    • Buck J, Furtig B, Noeske J, Wohnert J, Schwalbe H. 2007. Time-resolved NMR methods resolving ligand-induced RNA folding at atomic resolution. Proc. Natl. Acad. Sci. USA 104:15699-704
    • (2007) Proc. Natl. Acad. Sci. USA , vol.104 , pp. 15699-15704
    • Buck, J.1    Furtig, B.2    Noeske, J.3    Wohnert, J.4    Schwalbe, H.5
  • 12
    • 79953052076 scopus 로고    scopus 로고
    • Structural basis of cooperative ligand binding by the glycine riboswitch
    • Butler EB, Xiong Y, Wang J, Strobel SA. 2011. Structural basis of cooperative ligand binding by the glycine riboswitch. Chem. Biol. 18:293-98
    • (2011) Chem. Biol. , vol.18 , pp. 293-298
    • Butler, E.B.1    Xiong, Y.2    Wang, J.3    Strobel, S.A.4
  • 13
    • 33846279049 scopus 로고    scopus 로고
    • Structural investigation of the GlmS ribozyme bound to its catalytic cofactor
    • Cochrane JC, Lipchock SV, Strobel SA. 2007. Structural investigation of the GlmS ribozyme bound to its catalytic cofactor. Chem. Biol. 14:97-105
    • (2007) Chem. Biol. , vol.14 , pp. 97-105
    • Cochrane, J.C.1    Lipchock, S.V.2    Strobel, S.A.3
  • 14
    • 37249040135 scopus 로고    scopus 로고
    • Mechanism of mRNA destabilization by the glmS ribozyme
    • Collins JA, Irnov I, Baker S, Winkler WC. 2007. Mechanism of mRNA destabilization by the glmS ribozyme. Genes. Dev. 21:3356-68
    • (2007) Genes. Dev. , vol.21 , pp. 3356-3368
    • Collins, J.A.1    Irnov, I.2    Baker, S.3    Winkler, W.C.4
  • 15
    • 32044442926 scopus 로고    scopus 로고
    • Evidence for a second class of S-adenosylmethionine riboswitches and other regulatory RNA motifs in alpha-proteobacteria
    • Corbino KA, Barrick JE, Lim J, Welz R, Tucker BJ, et al. 2005. Evidence for a second class of S-adenosylmethionine riboswitches and other regulatory RNA motifs in alpha-proteobacteria. Genome Biol. 6:R70
    • (2005) Genome Biol. , vol.6
    • Corbino, K.A.1    Barrick, J.E.2    Lim, J.3    Welz, R.4    Tucker, B.J.5
  • 16
    • 0030856333 scopus 로고    scopus 로고
    • Metals, motifs, and recognition in the crystal structure of a 5S rRNA domain
    • Correll CC, Freeborn B, Moore PB, Steitz TA. 1997. Metals, motifs, and recognition in the crystal structure of a 5S rRNA domain. Cell 91:705-12
    • (1997) Cell , vol.91 , pp. 705-712
    • Correll, C.C.1    Freeborn, B.2    Moore, P.B.3    Steitz, T.A.4
  • 23
    • 58149138753 scopus 로고    scopus 로고
    • /-deoxyguanosine by the purine riboswitch
    • /-deoxyguanosine by the purine riboswitch. J. Mol. Biol. 385:938-48
    • (2009) J. Mol. Biol. , vol.385 , pp. 938-948
    • Edwards, A.L.1    Batey, R.T.2
  • 24
    • 78149300889 scopus 로고    scopus 로고
    • Structural basis for recognition of S-adenosylhomocysteine by riboswitches
    • Edwards AL, Reyes FE, Heroux A, Batey RT. 2010. Structural basis for recognition of S-adenosylhomocysteine by riboswitches. RNA 16:2144-55
    • (2010) RNA , vol.16 , pp. 2144-2155
    • Edwards, A.L.1    Reyes, F.E.2    Heroux, A.3    Batey, R.T.4
  • 25
    • 33748300801 scopus 로고    scopus 로고
    • Crystal structures of the thi-box riboswitch bound to thiamine pyrophosphate analogs reveal adaptive RNA-small molecule recognition
    • Edwards TE, Ferre-D'Amare AR. 2006. Crystal structures of the thi-box riboswitch bound to thiamine pyrophosphate analogs reveal adaptive RNA-small molecule recognition. Structure 14:1459-68
    • (2006) Structure , vol.14 , pp. 1459-1468
    • Edwards, T.E.1    Ferre-D'Amare, A.R.2
  • 27
    • 0038476616 scopus 로고    scopus 로고
    • The riboswitch-mediated control of sulfur metabolism in bacteria
    • Epshtein V, Mironov AS, Nudler E. 2003. The riboswitch-mediated control of sulfur metabolism in bacteria. Proc. Natl. Acad. Sci. USA 100:5052-56
    • (2003) Proc. Natl. Acad. Sci. USA , vol.100 , pp. 5052-5056
    • Epshtein, V.1    Mironov, A.S.2    Nudler, E.3
  • 28
    • 33644792751 scopus 로고    scopus 로고
    • The SMK box is a new SAM-binding RNA for translational regulation of SAM synthetase
    • Fuchs RT, Grundy FJ, Henkin TM. 2006. The SMK box is a new SAM-binding RNA for translational regulation of SAM synthetase. Nat. Struct. Mol. Biol. 13:226-33
    • (2006) Nat. Struct. Mol. Biol. , vol.13 , pp. 226-233
    • Fuchs, R.T.1    Grundy, F.J.2    Henkin, T.M.3
  • 29
    • 53049094260 scopus 로고    scopus 로고
    • Crystal structure of the lysine riboswitch regulatory mRNA element
    • Garst AD, Heroux A, Rambo RP, Batey RT. 2008. Crystal structure of the lysine riboswitch regulatory mRNA element. J. Biol. Chem. 283:22347-51
    • (2008) J. Biol. Chem. , vol.283 , pp. 22347-22351
    • Garst, A.D.1    Heroux, A.2    Rambo, R.P.3    Batey, R.T.4
  • 31
    • 33646768226 scopus 로고    scopus 로고
    • Thermodynamic and kinetic characterization of ligand binding to the purine riboswitch aptamer domain
    • Gilbert SD, Stoddard CD, Wise SJ, Batey RT. 2006. Thermodynamic and kinetic characterization of ligand binding to the purine riboswitch aptamer domain. J. Mol. Biol. 359:754-68
    • (2006) J. Mol. Biol. , vol.359 , pp. 754-768
    • Gilbert, S.D.1    Stoddard, C.D.2    Wise, S.J.3    Batey, R.T.4
  • 33
    • 0027234192 scopus 로고
    • TRNA as a positive regulator of transcription antitermination in B. subtilis
    • Grundy FJ, Henkin TM. 1993. tRNA as a positive regulator of transcription antitermination in B. subtilis. Cell 74:475-82
    • (1993) Cell , vol.74 , pp. 475-482
    • Grundy, F.J.1    Henkin, T.M.2
  • 34
    • 0142123125 scopus 로고    scopus 로고
    • The L box regulon: Lysine sensing by leader RNAs of bacterial lysine biosynthesis genes
    • Grundy FJ, Lehman SC, Henkin TM. 2003. The L box regulon: lysine sensing by leader RNAs of bacterial lysine biosynthesis genes. Proc. Natl. Acad. Sci. USA 100:12057-62
    • (2003) Proc. Natl. Acad. Sci. USA , vol.100 , pp. 12057-12062
    • Grundy, F.J.1    Lehman, S.C.2    Henkin, T.M.3
  • 36
    • 80052982281 scopus 로고    scopus 로고
    • The dynamic nature of RNA as key to understanding riboswitch mechanisms
    • Haller A, Souliere MF, Micura R. 2011. The dynamic nature of RNA as key to understanding riboswitch mechanisms. Acc. Chem. Res. 44:1339-48
    • (2011) Acc. Chem. Res. , vol.44 , pp. 1339-1348
    • Haller, A.1    Souliere, M.F.2    Micura, R.3
  • 37
    • 33746920364 scopus 로고    scopus 로고
    • Evidence for preorganization of the glmS ribozyme ligand binding pocket
    • Hampel KJ, Tinsley MM. 2006. Evidence for preorganization of the glmS ribozyme ligand binding pocket. Biochemistry 45:7861-71
    • (2006) Biochemistry , vol.45 , pp. 7861-7871
    • Hampel, K.J.1    Tinsley, M.M.2
  • 38
    • 79956101942 scopus 로고    scopus 로고
    • Molecular insights into the ligand-controlled organization of the SAM-I riboswitch
    • Heppell B, Blouin S, Dussault AM, Mulhbacher J, Ennifar E, et al. 2011. Molecular insights into the ligand-controlled organization of the SAM-I riboswitch. Nat. Chem. Biol. 7:384-92
    • (2011) Nat. Chem. Biol. , vol.7 , pp. 384-392
    • Heppell, B.1    Blouin, S.2    Dussault, A.M.3    Mulhbacher, J.4    Ennifar, E.5
  • 39
    • 80052602449 scopus 로고    scopus 로고
    • Long-range pseudoknot interactions dictate the regulatory response in the tetrahydrofolate riboswitch
    • Huang L, Ishibe-Murakami S, Patel DJ, Serganov A. 2011. Long-range pseudoknot interactions dictate the regulatory response in the tetrahydrofolate riboswitch. Proc. Natl. Acad. Sci. USA 108:14801-6
    • (2011) Proc. Natl. Acad. Sci. USA , vol.108 , pp. 14801-14806
    • Huang, L.1    Ishibe-Murakami, S.2    Patel, D.J.3    Serganov, A.4
  • 40
    • 78649970557 scopus 로고    scopus 로고
    • Structural insights into ligand recognition by a sensing domain of the cooperative glycine riboswitch
    • Huang L, Serganov A, Patel DJ. 2010. Structural insights into ligand recognition by a sensing domain of the cooperative glycine riboswitch. Mol. Cell 40:774-86
    • (2010) Mol. Cell , vol.40 , pp. 774-786
    • Huang, L.1    Serganov, A.2    Patel, D.J.3
  • 41
    • 71049194730 scopus 로고    scopus 로고
    • A mechanism for S-adenosyl methionine assisted formation of a riboswitch conformation: A small molecule with a strong arm
    • Huang W, Kim J, Jha S, Aboul-ela F. 2009. A mechanism for S-adenosyl methionine assisted formation of a riboswitch conformation: a small molecule with a strong arm. Nucleic Acids Res. 37:6528-39
    • (2009) Nucleic Acids Res. , vol.37 , pp. 6528-6539
    • Huang, W.1    Kim, J.2    Jha, S.3    Aboul-Ela, F.4
  • 42
    • 58549119994 scopus 로고    scopus 로고
    • The UA-handle: A versatile submotif in stable RNA architectures
    • Jaeger L, Verzemnieks EJ, Geary C. 2009. The UA-handle: a versatile submotif in stable RNA architectures. Nucleic Acids Res. 37:215-30
    • (2009) Nucleic Acids Res. , vol.37 , pp. 215-230
    • Jaeger, L.1    Verzemnieks, E.J.2    Geary, C.3
  • 43
    • 77951688391 scopus 로고    scopus 로고
    • Heterogeneity and dynamics of the ligand recognition mode in purine-sensing riboswitches
    • Jain N, Zhao L, Liu JD, Xia T. 2010. Heterogeneity and dynamics of the ligand recognition mode in purine-sensing riboswitches. Biochemistry 49:3703-14
    • (2010) Biochemistry , vol.49 , pp. 3703-3714
    • Jain, N.1    Zhao, L.2    Liu, J.D.3    Xia, T.4
  • 44
    • 79960114180 scopus 로고    scopus 로고
    • Comparison of a preQ1 riboswitch aptamer in metabolite-bound and free states with implications for gene regulation
    • Jenkins JL, Krucinska J, McCarty RM, Bandarian V, Wedekind JE. 2011. Comparison of a preQ1 riboswitch aptamer in metabolite-bound and free states with implications for gene regulation. J. Biol. Chem. 286:24626-37
    • (2011) J. Biol. Chem. , vol.286 , pp. 24626-24637
    • Jenkins, J.L.1    Krucinska, J.2    McCarty, R.M.3    Bandarian, V.4    Wedekind, J.E.5
  • 45
    • 62549154008 scopus 로고    scopus 로고
    • Structural insights into riboswitch control of the biosynthesis of queuosine, a modified nucleotide found in the anticodon of tRNA
    • Kang M, Peterson R, Feigon J. 2009. Structural insights into riboswitch control of the biosynthesis of queuosine, a modified nucleotide found in the anticodon of tRNA. Mol. Cell 33:784-90
    • (2009) Mol. Cell , vol.33 , pp. 784-790
    • Kang, M.1    Peterson, R.2    Feigon, J.3
  • 46
    • 73449116019 scopus 로고    scopus 로고
    • Design and antimicrobial action of purine analogues that bind guanine riboswitches
    • Kim JN, Blount KF, Puskarz I, Lim J, Link KH, et al. 2009. Design and antimicrobial action of purine analogues that bind guanine riboswitches. ACS Chem. Biol. 4:915-27
    • (2009) ACS Chem. Biol. , vol.4 , pp. 915-927
    • Kim, J.N.1    Blount, K.F.2    Puskarz, I.3    Lim, J.4    Link, K.H.5
  • 48
    • 78650028802 scopus 로고    scopus 로고
    • Analysis of metal ion dependence in glmS ribozyme self-cleavage and coenzyme binding
    • Klawuhn K, Jansen JA, Souchek J, Soukup GA, Soukup JK. 2010. Analysis of metal ion dependence in glmS ribozyme self-cleavage and coenzyme binding. Chembiochem 11:2567-71
    • (2010) Chembiochem , vol.11 , pp. 2567-2571
    • Klawuhn, K.1    Jansen, J.A.2    Souchek, J.3    Soukup, G.A.4    Soukup, J.K.5
  • 49
    • 62049086072 scopus 로고    scopus 로고
    • Cocrystal structure of a class i preQ1 riboswitch reveals a pseudoknot recognizing an essential hypermodified nucleobase
    • Klein DJ, Edwards TE, Ferre-DAmare AR. 2009. Cocrystal structure of a class I preQ1 riboswitch reveals a pseudoknot recognizing an essential hypermodified nucleobase. Nat. Struct. Mol. Biol. 16:343-44
    • (2009) Nat. Struct. Mol. Biol. , vol.16 , pp. 343-344
    • Klein, D.J.1    Edwards, T.E.2    Ferre-Damare, A.R.3
  • 50
    • 33748325570 scopus 로고    scopus 로고
    • Structural basis of glmS ribozyme activation by glucosamine-6-phosphate
    • Klein DJ, Ferre-DAmare AR. 2006. Structural basis of glmS ribozyme activation by glucosamine-6-phosphate. Science 313:1752-56
    • (2006) Science , vol.313 , pp. 1752-1756
    • Klein, D.J.1    Ferre-Damare, A.R.2
  • 51
  • 52
    • 34548591567 scopus 로고    scopus 로고
    • Requirement of helix P2.2 and nucleotide G1 for positioning the cleavage site and cofactor of the glmS ribozyme
    • Klein DJ, Wilkinson SR, Been MD, Ferre-DAmare AR. 2007. Requirement of helix P2.2 and nucleotide G1 for positioning the cleavage site and cofactor of the glmS ribozyme. J. Mol. Biol. 373:178-89
    • (2007) J. Mol. Biol. , vol.373 , pp. 178-189
    • Klein, D.J.1    Wilkinson, S.R.2    Been, M.D.3    Ferre-Damare, A.R.4
  • 53
    • 0038475947 scopus 로고    scopus 로고
    • On the occurrence of the T-loop RNA folding motif in large RNA molecules
    • Krasilnikov AS, Mondragon A. 2008. On the occurrence of the T-loop RNA folding motif in large RNA molecules. RNA 9:640-43
    • (2008) RNA , vol.9 , pp. 640-643
    • Krasilnikov, A.S.1    Mondragon, A.2
  • 54
    • 71449123530 scopus 로고    scopus 로고
    • Recognition of the bacterial second messenger cyclic diguanylate by its cognate riboswitch
    • Kulshina N, Baird NJ, Ferre-DAmare AR. 2009. Recognition of the bacterial second messenger cyclic diguanylate by its cognate riboswitch. Nat. Struct. Mol. Biol. 16:1212-27
    • (2009) Nat. Struct. Mol. Biol. , vol.16 , pp. 1212-1227
    • Kulshina, N.1    Baird, N.J.2    Ferre-Damare, A.R.3
  • 55
    • 38049025288 scopus 로고    scopus 로고
    • Chemical basis of glycine riboswitch cooperativity
    • Kwon M, Strobel SA. 2008. Chemical basis of glycine riboswitch cooperativity. RNA 14:25-34
    • (2008) RNA , vol.14 , pp. 25-34
    • Kwon, M.1    Strobel, S.A.2
  • 56
    • 34548761368 scopus 로고    scopus 로고
    • Ligand-induced folding of the thiM TPP riboswitch investigated by a structure-based fluorescence spectroscopic approach
    • Lang K, Rieder R, Micura R. 2007. Ligand-induced folding of the thiM TPP riboswitch investigated by a structure-based fluorescence spectroscopic approach. Nucleic Acids Res. 35:5370-78
    • (2007) Nucleic Acids Res. , vol.35 , pp. 5370-5378
    • Lang, K.1    Rieder, R.2    Micura, R.3
  • 57
    • 77955630859 scopus 로고    scopus 로고
    • An allosteric self-splicing ribozyme triggered by a bacterial second messenger
    • Lee ER, Baker JL, Weinberg Z, Sudarsan N, Breaker RR. 2010. An allosteric self-splicing ribozyme triggered by a bacterial second messenger. Science 329:845-48
    • (2010) Science , vol.329 , pp. 845-848
    • Lee, E.R.1    Baker, J.L.2    Weinberg, Z.3    Sudarsan, N.4    Breaker, R.R.5
  • 58
    • 77952700860 scopus 로고    scopus 로고
    • Real-time multidimensional NMR follows RNA folding with second resolution
    • Lee MK, Gal M, Frydman L, Varani G. 2010. Real-time multidimensional NMR follows RNA folding with second resolution. Proc. Natl. Acad. Sci. USA 107:9192-97
    • (2010) Proc. Natl. Acad. Sci. USA , vol.107 , pp. 9192-9197
    • Lee, M.K.1    Gal, M.2    Frydman, L.3    Varani, G.4
  • 59
    • 79851499341 scopus 로고    scopus 로고
    • Comparative study between transcriptionally-and translationally-acting adenine riboswitches reveals key differences in riboswitch regulatory mechanisms
    • Lemay JF, Desnoyers G, Blouin S, Heppell B, Bastet L, et al. 2011. Comparative study between transcriptionally-and translationally-acting adenine riboswitches reveals key differences in riboswitch regulatory mechanisms. PLoS Genet. 7:e1001278
    • (2011) PLoS Genet. , vol.7
    • Lemay, J.F.1    Desnoyers, G.2    Blouin, S.3    Heppell, B.4    Bastet, L.5
  • 60
    • 33847308180 scopus 로고    scopus 로고
    • Core requirements ofthe adenine riboswitch aptamer for ligand binding
    • Lemay JF, Lafontaine DA. 2007. Core requirements ofthe adenine riboswitch aptamer for ligand binding. RNA 13:339-50
    • (2007) RNA , vol.13 , pp. 339-350
    • Lemay, J.F.1    Lafontaine, D.A.2
  • 62
    • 33750149294 scopus 로고    scopus 로고
    • Characteristics of ligand recognition by a glmS self-cleaving ribozyme
    • Lim J, Grove BC, Roth A, Breaker RR. 2006. Characteristics of ligand recognition by a glmS self-cleaving ribozyme. Angew. Chem. Int. Ed. Engl. 45:6689-93
    • (2006) Angew. Chem. Int. Ed. Engl. , vol.45 , pp. 6689-6693
    • Lim, J.1    Grove, B.C.2    Roth, A.3    Breaker, R.R.4
  • 63
    • 33845971464 scopus 로고    scopus 로고
    • Structural transitions and thermodynamics of a glycine-dependent riboswitch from Vibrio cholerae
    • Lipfert J, Das R, Chu VB, Kudaravalli M, Boyd N, et al. 2007. Structural transitions and thermodynamics of a glycine-dependent riboswitch from Vibrio cholerae.J. Mol. Biol. 365:1393-406
    • (2007) J. Mol. Biol. , vol.365 , pp. 1393-1406
    • Lipfert, J.1    Das, R.2    Chu, V.B.3    Kudaravalli, M.4    Boyd, N.5
  • 64
    • 70350771280 scopus 로고    scopus 로고
    • A trans-acting riboswitch controls expression ofthe virulence regulator PrfA in Listeria monocytogenes
    • Loh E, Dussurget O, Gripenland J, Vaitkevicius K, Tiensuu T, et al. 2009. A trans-acting riboswitch controls expression ofthe virulence regulator PrfA in Listeria monocytogenes. Cell 139:770-79
    • (2009) Cell , vol.139 , pp. 770-779
    • Loh, E.1    Dussurget, O.2    Gripenland, J.3    Vaitkevicius, K.4    Tiensuu, T.5
  • 65
    • 53549089576 scopus 로고    scopus 로고
    • Crystal structures ofthe SAM-III/SMK riboswitch reveal the SAM-dependent translation inhibition mechanism
    • Lu C, Smith AM, Fuchs RT, Ding F, Rajashankar K, et al. 2008. Crystal structures ofthe SAM-III/SMK riboswitch reveal the SAM-dependent translation inhibition mechanism. Nat. Struct. Mol. Biol. 15:1076-83
    • (2008) Nat. Struct. Mol. Biol. , vol.15 , pp. 1076-1083
    • Lu, C.1    Smith, A.M.2    Fuchs, R.T.3    Ding, F.4    Rajashankar, K.5
  • 66
    • 0038210214 scopus 로고    scopus 로고
    • Riboswitches control fundamental biochemical pathways in Bacillussubtilis and other bacteria
    • Mandal M, Boese B, Barrick JE, Winkler WC, Breaker RR. 2003. Riboswitches control fundamental biochemical pathways in Bacillussubtilis and other bacteria. Cell 113:577-86
    • (2003) Cell , vol.113 , pp. 577-586
    • Mandal, M.1    Boese, B.2    Barrick, J.E.3    Winkler, W.C.4    Breaker, R.R.5
  • 67
    • 0842334528 scopus 로고    scopus 로고
    • Adenine riboswitches and gene activation by disruption of a transcription terminator
    • Mandal M, Breaker RR. 2004. Adenine riboswitches and gene activation by disruption of a transcription terminator. Nat. Struct. Mol. Biol. 11:29-35
    • (2004) Nat. Struct. Mol. Biol. , vol.11 , pp. 29-35
    • Mandal, M.1    Breaker, R.R.2
  • 68
    • 5044234799 scopus 로고    scopus 로고
    • A glycine-dependent riboswitch that uses cooperative binding to control gene expression
    • Mandal M, Lee M, Barrick JE, Weinberg Z, Emilsson GM, et al. 2004. A glycine-dependent riboswitch that uses cooperative binding to control gene expression. Science 306:275-79
    • (2004) Science , vol.306 , pp. 275-279
    • Mandal, M.1    Lee, M.2    Barrick, J.E.3    Weinberg, Z.4    Emilsson, G.M.5
  • 70
    • 0037453069 scopus 로고    scopus 로고
    • Transcription termination control ofthe S box system: Direct measurement of S-adenosylmethionine by the leader RNA
    • McDaniel BA, Grundy FJ, Artsimovitch I, Henkin TM. 2003. Transcription termination control ofthe S box system: direct measurement of S-adenosylmethionine by the leader RNA. Proc. Natl. Acad. Sci. USA 100:3083-88
    • (2003) Proc. Natl. Acad. Sci. USA , vol.100 , pp. 3083-3088
    • McDaniel, B.A.1    Grundy, F.J.2    Artsimovitch, I.3    Henkin, T.M.4
  • 72
    • 41649108068 scopus 로고    scopus 로고
    • Confirmation of a second natural preQ1 aptamer class in Streptococcaceae bacteria
    • Meyer MM, Roth A, Chervin SM, Garcia GA, Breaker RR. 2008. Confirmation of a second natural preQ1 aptamer class in Streptococcaceae bacteria. RNA 14:685-95
    • (2008) RNA , vol.14 , pp. 685-695
    • Meyer, M.M.1    Roth, A.2    Chervin, S.M.3    Garcia, G.A.4    Breaker, R.R.5
  • 73
    • 18744396047 scopus 로고    scopus 로고
    • Sensing small molecules by nascent RNA: A mechanism to control transcription in bacteria
    • Mironov AS, Gusarov I, Rafikov R, Lopez LE, Shatalin K, et al. 2002. Sensing small molecules by nascent RNA: a mechanism to control transcription in bacteria. Cell 111:747-56
    • (2002) Cell , vol.111 , pp. 747-756
    • Mironov, A.S.1    Gusarov, I.2    Rafikov, R.3    Lopez, L.E.4    Shatalin, K.5
  • 74
    • 33745628336 scopus 로고    scopus 로고
    • Structure of the S-adenosylmethionine riboswitch regulatory mRNA element
    • Montange RK, Batey RT. 2006. Structure of the S-adenosylmethionine riboswitch regulatory mRNA element. Nature 441:1172-75
    • (2006) Nature , vol.441 , pp. 1172-1175
    • Montange, R.K.1    Batey, R.T.2
  • 75
    • 48249104039 scopus 로고    scopus 로고
    • Riboswitches: Emerging themes in RNA structure and function
    • Montange RK, Batey RT. 2008. Riboswitches: emerging themes in RNA structure and function. Annu. Rev. Biophys. 37:117-33
    • (2008) Annu. Rev. Biophys. , vol.37 , pp. 117-133
    • Montange, R.K.1    Batey, R.T.2
  • 76
    • 77954079519 scopus 로고    scopus 로고
    • Novel riboswitch ligand analogs as selective inhibitors of guanine-related metabolic pathways
    • Mulhbacher J, Brouillette E, Allard M, Fortier LC, Malouin F, et al. 2010. Novel riboswitch ligand analogs as selective inhibitors of guanine-related metabolic pathways. PLoS Pathog. 6:e1000865
    • (2010) PLoS Pathog. , vol.6
    • Mulhbacher, J.1    Brouillette, E.2    Allard, M.3    Fortier, L.C.4    Malouin, F.5
  • 77
    • 34548726217 scopus 로고    scopus 로고
    • Ligand recognition determinants of guanine riboswitches
    • Mulhbacher J, Lafontaine DA. 2007. Ligand recognition determinants of guanine riboswitches. Nucleic Acids Res. 35:5568-80
    • (2007) Nucleic Acids Res. , vol.35 , pp. 5568-5580
    • Mulhbacher, J.1    Lafontaine, D.A.2
  • 78
    • 0036717041 scopus 로고    scopus 로고
    • Frequent occurrence of the T-loop RNA folding motif in ribosomal RNAs
    • Nagaswamy U, Fox GE. 2002. Frequent occurrence of the T-loop RNA folding motif in ribosomal RNAs. RNA 8:1112-19
    • (2002) RNA , vol.8 , pp. 1112-1119
    • Nagaswamy, U.1    Fox, G.E.2
  • 79
    • 1242320304 scopus 로고    scopus 로고
    • Coenzyme B12 riboswitches are widespread genetic control elements in prokaryotes
    • Nahvi A, Barrick JE, Breaker RR. 2004. Coenzyme B12 riboswitches are widespread genetic control elements in prokaryotes. Nucleic Acids Res. 32:143-50
    • (2004) Nucleic Acids Res. , vol.32 , pp. 143-150
    • Nahvi, A.1    Barrick, J.E.2    Breaker, R.R.3
  • 81
    • 80053216036 scopus 로고    scopus 로고
    • Single-molecule force spectroscopy of the add adenine riboswitch relates folding to regulatory mechanism
    • Neupane K, Yu H, Foster DA, Wang F, Woodside MT. 2011. Single-molecule force spectroscopy of the add adenine riboswitch relates folding to regulatory mechanism. Nucleic Acids Res. 39:7677-87
    • (2011) Nucleic Acids Res. , vol.39 , pp. 7677-7687
    • Neupane, K.1    Yu, H.2    Foster, D.A.3    Wang, F.4    Woodside, M.T.5
  • 83
    • 33846898497 scopus 로고    scopus 로고
    • Interplay of'induced fit' and preorga-nization in the ligand induced folding of the aptamer domain of the guanine binding riboswitch
    • Noeske J, Buck J, Furtig B, Nasiri HR, Schwalbe H, et al. 2007. Interplay of'induced fit' and preorga-nization in the ligand induced folding of the aptamer domain of the guanine binding riboswitch. Nucleic Acids Res. 35:572-83
    • (2007) Nucleic Acids Res. , vol.35 , pp. 572-583
    • Noeske, J.1    Buck, J.2    Furtig, B.3    Nasiri, H.R.4    Schwalbe, H.5
  • 84
    • 13444271576 scopus 로고    scopus 로고
    • An intermolecular base triple as the basis of ligand specificity and affinity in the guanine-and adenine-sensing riboswitch RNAs
    • Noeske J, Richter C, Grundl MA, Nasiri HR, Schwalbe H, et al. 2005. An intermolecular base triple as the basis of ligand specificity and affinity in the guanine-and adenine-sensing riboswitch RNAs. Proc. Natl. Acad. Sci. USA 102:1372-77
    • (2005) Proc. Natl. Acad. Sci. USA , vol.102 , pp. 1372-1377
    • Noeske, J.1    Richter, C.2    Grundl, M.A.3    Nasiri, H.R.4    Schwalbe, H.5
  • 85
    • 0346687595 scopus 로고    scopus 로고
    • The riboswitch control of bacterial metabolism
    • Nudler E, Mironov AS. 2004. The riboswitch control of bacterial metabolism. Trends Biochem. Sci. 29:11-17
    • (2004) Trends Biochem. Sci. , vol.29 , pp. 11-17
    • Nudler, E.1    Mironov, A.S.2
  • 86
    • 36248984806 scopus 로고    scopus 로고
    • Ligand-induced folding of the guanine-sensing riboswitch is controlled by a combined predetermined induced fit mechanism
    • Ottink OM, Rampersad SM, Tessari M, Zaman GJ, Heus HA, et al. 2007. Ligand-induced folding of the guanine-sensing riboswitch is controlled by a combined predetermined induced fit mechanism. RNA 13:2202-12
    • (2007) RNA , vol.13 , pp. 2202-2212
    • Ottink, O.M.1    Rampersad, S.M.2    Tessari, M.3    Zaman, G.J.4    Heus, H.A.5
  • 87
    • 77956148437 scopus 로고    scopus 로고
    • A bacterial mRNA leader that employs different mechanisms to sense disparate intracellular signals
    • Park SY, Cromie MJ, Lee EJ, Groisman EA. 2010. A bacterial mRNA leader that employs different mechanisms to sense disparate intracellular signals. Cell 142:737-48
    • (2010) Cell , vol.142 , pp. 737-748
    • Park, S.Y.1    Cromie, M.J.2    Lee, E.J.3    Groisman, E.A.4
  • 89
    • 70350111141 scopus 로고    scopus 로고
    • A variant riboswitch aptamer class for S-adenosylmethionine common in marine bacteria
    • Poiata E, Meyer MM, Ames TD, Breaker RR. 2009. A variant riboswitch aptamer class for S-adenosylmethionine common in marine bacteria. RNA 15:2046-56
    • (2009) RNA , vol.15 , pp. 2046-2056
    • Poiata, E.1    Meyer, M.M.2    Ames, T.D.3    Breaker, R.R.4
  • 90
    • 79952444960 scopus 로고    scopus 로고
    • Insights into metalloregulation by M-box riboswitch RNAs via structural analysis of manganese-bound complexes
    • Ramesh A, Wakeman CA, Winkler WC. 2011. Insights into metalloregulation by M-box riboswitch RNAs via structural analysis of manganese-bound complexes. J. Mol. Biol. 407:556-70
    • (2011) J. Mol. Biol. , vol.407 , pp. 556-570
    • Ramesh, A.1    Wakeman, C.A.2    Winkler, W.C.3
  • 91
    • 42549108780 scopus 로고    scopus 로고
    • A widespread riboswitch candidate that controls bacterial genes involved in molybdenum cofactor and tungsten cofactor metabolism
    • Regulski EE, Moy RH, Weinberg Z, Barrick JE, Yao Z, et al. 2008. A widespread riboswitch candidate that controls bacterial genes involved in molybdenum cofactor and tungsten cofactor metabolism. Mol. Microbiol. 68:918-32
    • (2008) Mol. Microbiol. , vol.68 , pp. 918-932
    • Regulski, E.E.1    Moy, R.H.2    Weinberg, Z.3    Barrick, J.E.4    Yao, Z.5
  • 92
    • 34447548824 scopus 로고    scopus 로고
    • Ligand-induced folding of the adenosine deaminase A-riboswitch and implications on riboswitch translational control
    • Rieder R, Lang K, Graber D, Micura R. 2007. Ligand-induced folding of the adenosine deaminase A-riboswitch and implications on riboswitch translational control. Chembiochem 8:896-902
    • (2007) Chembiochem , vol.8 , pp. 896-902
    • Rieder, R.1    Lang, K.2    Graber, D.3    Micura, R.4
  • 93
    • 77954627972 scopus 로고    scopus 로고
    • Folding of a transcriptionally acting preQ1 riboswitch
    • Rieder U, Kreutz C, Micura R. 2010. Folding of a transcriptionally acting preQ1 riboswitch. Proc. Natl. Acad. Sci. USA 107:10804-9
    • (2010) Proc. Natl. Acad. Sci. USA , vol.107 , pp. 10804-10809
    • Rieder, U.1    Kreutz, C.2    Micura, R.3
  • 94
    • 0345531094 scopus 로고    scopus 로고
    • Regulation of lysine biosynthesis and transport genes in bacteria: Yet another RNA riboswitch?
    • Rodionov DA, Vitreschak AG, Mironov AA, Gelfand MS. 2003. Regulation of lysine biosynthesis and transport genes in bacteria: yet another RNA riboswitch? Nucleic Acids Res. 31:6748-57
    • (2003) Nucleic Acids Res. , vol.31 , pp. 6748-6757
    • Rodionov, D.A.1    Vitreschak, A.G.2    Mironov, A.A.3    Gelfand, M.S.4
  • 95
    • 67650713931 scopus 로고    scopus 로고
    • The structural and functional diversity of metabolite-binding riboswitches
    • Roth A, Breaker RR. 2009. The structural and functional diversity of metabolite-binding riboswitches. Annu. Rev. Biochem. 78:305-34
    • (2009) Annu. Rev. Biochem. , vol.78 , pp. 305-334
    • Roth, A.1    Breaker, R.R.2
  • 96
    • 33645462033 scopus 로고    scopus 로고
    • Characteristics of the glmS ribozyme suggest only structural roles for divalent metal ions
    • Roth A, Nahvi A, Lee M, Jona I, Breaker RR. 2006. Characteristics of the glmS ribozyme suggest only structural roles for divalent metal ions. RNA 12:607-19
    • (2006) RNA , vol.12 , pp. 607-619
    • Roth, A.1    Nahvi, A.2    Lee, M.3    Jona, I.4    Breaker, R.R.5
  • 97
    • 34247181095 scopus 로고    scopus 로고
    • Ariboswitch selective for the queuosine precursor preQ1 contains an unusually small aptamer domain
    • Roth A, Winkler WC, Regulski EE, Lee BW, Lim J, et al. 2007. Ariboswitch selective for the queuosine precursor preQ1 contains an unusually small aptamer domain. Nat. Struct. Mol. Biol. 14:308-17
    • (2007) Nat. Struct. Mol. Biol. , vol.14 , pp. 308-317
    • Roth, A.1    Winkler, W.C.2    Regulski, E.E.3    Lee, B.W.4    Lim, J.5
  • 98
    • 55249114833 scopus 로고    scopus 로고
    • Structural insights into amino acid binding and gene control by a lysine riboswitch
    • Serganov A, Huang L, Patel DJ. 2008. Structural insights into amino acid binding and gene control by a lysine riboswitch. Nature 455:1263-67
    • (2008) Nature , vol.455 , pp. 1263-1267
    • Serganov, A.1    Huang, L.2    Patel, D.J.3
  • 99
    • 62249156218 scopus 로고    scopus 로고
    • Coenzyme recognition and gene regulation by a flavin mononucleotide riboswitch
    • Serganov A, Huang L, Patel DJ. 2009. Coenzyme recognition and gene regulation by a flavin mononucleotide riboswitch. Nature 458:233-37
    • (2009) Nature , vol.458 , pp. 233-237
    • Serganov, A.1    Huang, L.2    Patel, D.J.3
  • 100
    • 34548778155 scopus 로고    scopus 로고
    • Ribozymes, riboswitches and beyond: Regulation of gene expression without proteins
    • Serganov A, Patel DJ. 2007. Ribozymes, riboswitches and beyond: regulation of gene expression without proteins. Nat. Rev. Genet. 8:776-90
    • (2007) Nat. Rev. Genet. , vol.8 , pp. 776-790
    • Serganov, A.1    Patel, D.J.2
  • 101
    • 33745635350 scopus 로고    scopus 로고
    • Structural basis for gene regulation by a thiamine pyrophosphate-sensing riboswitch
    • Serganov A, Polonskaia A, Phan AT, Breaker RR, Patel DJ. 2006. Structural basis for gene regulation by a thiamine pyrophosphate-sensing riboswitch. Nature 441:1167-71
    • (2006) Nature , vol.441 , pp. 1167-1171
    • Serganov, A.1    Polonskaia, A.2    Phan, A.T.3    Breaker, R.R.4    Patel, D.J.5
  • 102
    • 10644250950 scopus 로고    scopus 로고
    • Structural basis for discriminative regulation of gene expression by adenine-and guanine-sensing mRNAs
    • Serganov A, Yuan YR, Pikovskaya O, Polonskaia A, Malinina L, et al. 2004. Structural basis for discriminative regulation of gene expression by adenine-and guanine-sensing mRNAs. Chem. Biol. 11:1729-41
    • (2004) Chem. Biol. , vol.11 , pp. 1729-1741
    • Serganov, A.1    Yuan, Y.R.2    Pikovskaya, O.3    Polonskaia, A.4    Malinina, L.5
  • 103
  • 106
    • 0032831634 scopus 로고    scopus 로고
    • Relationship between internucleotide linkage geometry and the stability of RNA
    • Soukup GA, Breaker RR. 1999. Relationship between internucleotide linkage geometry and the stability of RNA. RNA 5:1308-25
    • (1999) RNA , vol.5 , pp. 1308-1325
    • Soukup, G.A.1    Breaker, R.R.2
  • 108
    • 66449089224 scopus 로고    scopus 로고
    • The structural basis for recognition of the PreQ0 metabolite by an unusually small riboswitch aptamer domain
    • Spitale RC, Torelli AT, Krucinska J, Bandarian V, Wedekind JE. 2009. The structural basis for recognition of the PreQ0 metabolite by an unusually small riboswitch aptamer domain. J. Biol. Chem. 284:11012-16
    • (2009) J. Biol. Chem. , vol.284 , pp. 11012-11016
    • Spitale, R.C.1    Torelli, A.T.2    Krucinska, J.3    Bandarian, V.4    Wedekind, J.E.5
  • 109
    • 41649108293 scopus 로고    scopus 로고
    • Ligand-dependent folding of the three-way junction in the purine riboswitch
    • Stoddard CD, Gilbert SD, Batey RT. 2008. Ligand-dependent folding of the three-way junction in the purine riboswitch. RNA 14:675-84
    • (2008) RNA , vol.14 , pp. 675-684
    • Stoddard, C.D.1    Gilbert, S.D.2    Batey, R.T.3
  • 111
    • 0038136962 scopus 로고    scopus 로고
    • Metabolite-binding RNA domains are present in the genes of eukaryotes
    • Sudarsan N, Barrick JE, Breaker RR. 2003. Metabolite-binding RNA domains are present in the genes of eukaryotes. RNA 9:644-47
    • (2003) RNA , vol.9 , pp. 644-647
    • Sudarsan, N.1    Barrick, J.E.2    Breaker, R.R.3
  • 112
    • 33749986680 scopus 로고    scopus 로고
    • Tandem riboswitch architectures exhibit complex gene control functions
    • Sudarsan N, Hammond MC, Block KF, Welz R, Barrick JE, et al. 2006. Tandem riboswitch architectures exhibit complex gene control functions. Science 314:300-4
    • (2006) Science , vol.314 , pp. 300-304
    • Sudarsan, N.1    Hammond, M.C.2    Block, K.F.3    Welz, R.4    Barrick, J.E.5
  • 113
    • 47749152941 scopus 로고    scopus 로고
    • Riboswitches in eubacteria sense the second messenger cyclic di-GMP
    • Sudarsan N, Lee ER, Weinberg Z, Moy RH, Kim JN, et al. 2008. Riboswitches in eubacteria sense the second messenger cyclic di-GMP. Science 321:411-13
    • (2008) Science , vol.321 , pp. 411-413
    • Sudarsan, N.1    Lee, E.R.2    Weinberg, Z.3    Moy, R.H.4    Kim, J.N.5
  • 114
    • 0242298623 scopus 로고    scopus 로고
    • An mRNA structure in bacteria that controls gene expression by binding lysine
    • Sudarsan N, Wickiser JK, Nakamura S, Ebert MS, Breaker RR. 2003. An mRNA structure in bacteria that controls gene expression by binding lysine. Genes Dev. 17:2688-97
    • (2003) Genes Dev. , vol.17 , pp. 2688-2697
    • Sudarsan, N.1    Wickiser, J.K.2    Nakamura, S.3    Ebert, M.S.4    Breaker, R.R.5
  • 115
    • 46049091176 scopus 로고    scopus 로고
    • Structural basis of thiamine pyrophosphate analogues binding to the eukaryotic riboswitch
    • Thore S, Frick C, Ban N. 2008. Structural basis of thiamine pyrophosphate analogues binding to the eukaryotic riboswitch. J. Am. Chem. Soc. 130:8116-17
    • (2008) J. Am. Chem. Soc. , vol.130 , pp. 8116-8117
    • Thore, S.1    Frick, C.2    Ban, N.3
  • 116
    • 33744469562 scopus 로고    scopus 로고
    • Structure of the eukaryotic thiamine pyrophosphate riboswitch with its regulatory ligand
    • Thore S, Leibundgut M, Ban N. 2006. Structure of the eukaryotic thiamine pyrophosphate riboswitch with its regulatory ligand. Science 312:1208-11
    • (2006) Science , vol.312 , pp. 1208-1211
    • Thore, S.1    Leibundgut, M.2    Ban, N.3
  • 117
    • 33947728975 scopus 로고    scopus 로고
    • Trans-acting glmS catalytic riboswitch: Locked and loaded
    • Tinsley RA, Furchak JR, Walter NG. 2007. Trans-acting glmS catalytic riboswitch: locked and loaded. RNA 13:468-77
    • (2007) RNA , vol.13 , pp. 468-477
    • Tinsley, R.A.1    Furchak, J.R.2    Walter, N.G.3
  • 118
    • 80054074740 scopus 로고    scopus 로고
    • The structure of a tetrahydrofolate-sensing riboswitch reveals two ligand binding sites in a single aptamer
    • Trausch JJ, Ceres P, Reyes FE, Batey RT. 2011. The structure of a tetrahydrofolate-sensing riboswitch reveals two ligand binding sites in a single aptamer. Structure 19:1413-23
    • (2011) Structure , vol.19 , pp. 1413-1423
    • Trausch, J.J.1    Ceres, P.2    Reyes, F.E.3    Batey, R.T.4
  • 119
    • 79960991166 scopus 로고    scopus 로고
    • Constitutive regulatory activity of an evolutionarily excluded riboswitch variant
    • Tremblay R, Lemay JF, Blouin S, Mulhbacher J, Bonneau E, et al. 2011. Constitutive regulatory activity of an evolutionarily excluded riboswitch variant. J. Biol. Chem. 286:27406-15
    • (2011) J. Biol. Chem. , vol.286 , pp. 27406-27415
    • Tremblay, R.1    Lemay, J.F.2    Blouin, S.3    Mulhbacher, J.4    Bonneau, E.5
  • 120
    • 80455178803 scopus 로고    scopus 로고
    • Molecular sensing by the aptamer domain of the FMN riboswitch: A general model for ligand binding by conformational selection
    • Vicens Q, Mondragón E, Batey RT. 2011. Molecular sensing by the aptamer domain of the FMN riboswitch: a general model for ligand binding by conformational selection. Nucleic Acids Res. 39:8586-98
    • (2011) Nucleic Acids Res. , vol.39 , pp. 8586-8598
    • Vicens, Q.1    Mondragón, E.2    Batey, R.T.3
  • 121
    • 85011940612 scopus 로고    scopus 로고
    • Riboswitch-mediated control of gene expression in eukaryotes
    • Wachter A. 2010. Riboswitch-mediated control of gene expression in eukaryotes. RNA Biol. 7:67-76
    • (2010) RNA Biol. , vol.7 , pp. 67-76
    • Wachter, A.1
  • 122
    • 69349104590 scopus 로고    scopus 로고
    • Multiple metal-binding cores are required for metal-loregulation by M-box riboswitch RNAs
    • Wakeman CA, Ramesh A, Winkler WC. 2009. Multiple metal-binding cores are required for metal-loregulation by M-box riboswitch RNAs. J. Mol. Biol. 392:723-35
    • (2009) J. Mol. Biol. , vol.392 , pp. 723-735
    • Wakeman, C.A.1    Ramesh, A.2    Winkler, W.C.3
  • 123
    • 42149091618 scopus 로고    scopus 로고
    • Riboswitches that sense S-adenosylmethionine and S-adenosylhomocysteine
    • Wang JX, Breaker RR. 2008. Riboswitches that sense S-adenosylmethionine and S-adenosylhomocysteine. Biochem. Cell Biol. 86:157-68
    • (2008) Biochem. Cell Biol. , vol.86 , pp. 157-168
    • Wang, J.X.1    Breaker, R.R.2
  • 124
    • 79952362042 scopus 로고    scopus 로고
    • The glmS riboswitch integrates signals from activating and inhibitory metabolites in vivo
    • Watson PY, Fedor MJ. 2011. The glmS riboswitch integrates signals from activating and inhibitory metabolites in vivo. Nat. Struct. Mol. Biol. 18:359-63
    • (2011) Nat. Struct. Mol. Biol. , vol.18 , pp. 359-363
    • Watson, P.Y.1    Fedor, M.J.2
  • 125
    • 40849104495 scopus 로고    scopus 로고
    • The aptamer core of SAM-IV riboswitches mimics the ligand-binding site of SAM-I riboswitches
    • Weinberg Z, Regulski EE, Hammond MC, Barrick JE, Yao Z, et al. 2008. The aptamer core of SAM-IV riboswitches mimics the ligand-binding site of SAM-I riboswitches. RNA 14:822-28
    • (2008) RNA , vol.14 , pp. 822-828
    • Weinberg, Z.1    Regulski, E.E.2    Hammond, M.C.3    Barrick, J.E.4    Yao, Z.5
  • 126
    • 77951606278 scopus 로고    scopus 로고
    • Comparative genomics reveals 104 candidate structured RNAs from bacteria, archaea, and their metagenomes
    • Weinberg Z, Wang JX, Bogue J, Yang J, Corbino K, et al. 2010. Comparative genomics reveals 104 candidate structured RNAs from bacteria, archaea, and their metagenomes. Genome Biol. 11:R31
    • (2010) Genome Biol. , vol.11
    • Weinberg, Z.1    Wang, J.X.2    Bogue, J.3    Yang, J.4    Corbino, K.5
  • 127
  • 128
    • 15944382675 scopus 로고    scopus 로고
    • The speed of RNA transcription and metabolite binding kinetics operate an FMN riboswitch
    • Wickiser JK, Winkler WC, Breaker RR, Crothers DM. 2005. The speed of RNA transcription and metabolite binding kinetics operate an FMN riboswitch. Mol. Cell 18:49-60
    • (2005) Mol. Cell , vol.18 , pp. 49-60
    • Wickiser, J.K.1    Winkler, W.C.2    Breaker, R.R.3    Crothers, D.M.4
  • 130
    • 0037206833 scopus 로고    scopus 로고
    • Thiamine derivatives bind messenger RNAs directly to regulate bacterial gene expression
    • Winkler W, Nahvi A, Breaker RR. 2002. Thiamine derivatives bind messenger RNAs directly to regulate bacterial gene expression. Nature 419:952-56
    • (2002) Nature , vol.419 , pp. 952-956
    • Winkler, W.1    Nahvi, A.2    Breaker, R.R.3
  • 131
    • 27144527479 scopus 로고    scopus 로고
    • Regulation of bacterial gene expression by riboswitches
    • Winkler WC, Breaker RR. 2005. Regulation of bacterial gene expression by riboswitches. Annu. Rev. Microbiol. 59:487-517
    • (2005) Annu. Rev. Microbiol. , vol.59 , pp. 487-517
    • Winkler, W.C.1    Breaker, R.R.2
  • 133
    • 1642586299 scopus 로고    scopus 로고
    • Control of gene expression by a natural metabolite-responsive ribozyme
    • Winkler WC, Nahvi A, Roth A, Collins JA, Breaker RR. 2004. Control of gene expression by a natural metabolite-responsive ribozyme. Nature 428:281-86
    • (2004) Nature , vol.428 , pp. 281-286
    • Winkler, W.C.1    Nahvi, A.2    Roth, A.3    Collins, J.A.4    Breaker, R.R.5
  • 135
    • 78049276834 scopus 로고    scopus 로고
    • Ribozymes and riboswitches: Modulation of RNA function by small molecules
    • Zhang J, Lau MW, Ferre-D'Amare AR. 2010. Ribozymes and riboswitches: modulation of RNA function by small molecules. Biochemistry 49:9123-31
    • (2010) Biochemistry , vol.49 , pp. 9123-9131
    • Zhang, J.1    Lau, M.W.2    Ferre-D'Amare, A.R.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.