Low-modulus PMMA bone cement modified with castor oil

Bio-Medical Materials and Engineering

Volumn 21, Issue 5-6, 2011, Pages 323-332

  López, Alejandro ^a   Hoess, Andreas ^a   Thersleff, Thomas ^a   Ott, Marjam ^a   Engqvist, Hkan ^a   Persson, Cecilia ^a  

^a UPPSALA UNIVERSITY   (Sweden)

Author keywords

Bone cement; castor oil; cytotoxicity; low modulus; PMMA

Indexed keywords

BIOMECHANICAL DATA; CANCELLOUS BONE; CASTOR OIL; CELL VIABILITY; COMPLEX VISCOSITY; HIGH INJECTION; LOW-MODULUS; OSTEOBLAST-LIKE CELLS; OSTEOPOROTIC; PMMA; PMMA BONE CEMENT; POLYMERIZATION REACTION; POLYMERIZATION TEMPERATURE; SETTING TIME; VERTEBRAL FRACTURES; VERTEBROPLASTY; WORST CASE SCENARIO; YOUNG'S MODULUS;

BIOMECHANICS; CELL CULTURE; CYTOTOXICITY; ELASTIC MODULI; ELASTICITY; PLASTICIZERS; POLYMERIZATION; VEGETABLE OILS; YIELD STRESS;

BONE CEMENT;

BIOMATERIAL; BONE CEMENT; CASTOR OIL; PLASTICIZER; POLY(METHYL METHACRYLATE);

ARTICLE; CELL CULTURE; CELL SURVIVAL; CHEMISTRY; COMPRESSIVE STRENGTH; CYTOLOGY; DRUG EFFECT; EVALUATION; HUMAN; MATERIALS TESTING; OSTEOBLAST; PHYSIOLOGY; SURFACE PROPERTY; SYNTHESIS; YOUNG MODULUS;

BONE CEMENTS; CASTOR OIL; CELL SURVIVAL; CELLS, CULTURED; COATED MATERIALS, BIOCOMPATIBLE; COMPRESSIVE STRENGTH; ELASTIC MODULUS; HUMANS; MATERIALS TESTING; OSTEOBLASTS; PLASTICIZERS; POLYMETHYL METHACRYLATE; SURFACE PROPERTIES;

EID: 84861405349     PISSN: 09592989     EISSN: None     Source Type: Journal    
DOI: 10.3233/BME-2012-0679     Document Type: Article

References (34)

1. G. Lewis, Injectable bone cements for use in vertebroplasty and kyphoplasty: State-of-the-art review, Journal of Biomedical Materials Research Part B: Applied Biomaterials 76B (2006), 456-468. (Pubitemid 43168280)
2. M.A. Liebschner,W.S. Rosenberg and T.M. Keaveny, Effects of bone cement volume and distribution on vertebral stiffness after vertebroplasty, Spine 26 (2001), 1547-1554. (Pubitemid 32646125)
3. P.F. Heini, U. Berlemann, M. Kaufmann, K. Lippuner, C. Fankhauser and P. van Landuyt, Augmentation of mechanical properties in osteoporotic vertebral bones - a biomechanical investigation of vertebroplasty efficacy with different bone cements, European Spine Journal 10 (2001), 164-171. (Pubitemid 32337046)
4. G. Baroud, J. Nemes, S.J. Ferguson and T. Steffen, Material changes in osteoporotic human cancellous bone following infiltration with acrylic bone cement for a vertebral cement augmentation, Computer Methods in Biomechanics and Biomedical Engineering 6 (2003), 133-139.
5. L. Hernandez, M.E. Muñoz, I. Goñi and M. Gurruchaga, New injectable and radiopaque antibiotic loaded acrylic bone cements, Journal of Biomedical Materials Research Part B: Applied Biomaterials 87B (2008), 312-320.
6. S.M. Kurtz, M.L. Villarraga, K. Zhao and A.A. Edidin, Static and fatigue mechanical behavior of bone cement with elevated barium sulfate content for treatment of vertebral compression fractures, Biomaterials 26 (2005), 3699-3712. (Pubitemid 40038165)
7. A. Boger, M. Bohner, P. Heini, S. Verrier and E. Schneider, Properties of an injectable low modulus PMMA bone cement for osteoporotic bone, Journal of Biomedical Materials Research Part B: Applied Biomaterials 86B (2008), 474-482.
8. A. Nazarian, D. von Stechow, D. Zurakowski, R. Müller and B. Snyder, Bone volume fraction explains the variation in strength and stiffness of cancellous bone affected by metastatic cancer and osteoporosis, Calcified Tissue International 83 (2008), 368-379.
9. F. Grados, C. Depriester, G. Cayrolle, N. Hardy, H. Deramond and P. Fardellone, Long-term observations of vertebral osteoporotic fractures treated by percutaneous vertebroplasty, SAS Journal 3 (2009), 118-122.
10. A.A. Uppin, J.A. Hirsch, L.V. Centenera, B.A. Pfiefer, A.G. Pazianos and I.S. Choi, Occurrence of new vertebral body fracture after percutaneous vertebroplasty in patients with osteoporosis, Radiology 226 (2003), 119-124. (Pubitemid 36163918)
11. A.T. Trout, D.F. Kallmes and T.J. Kaufmann, New fractures after vertebroplasty: adjacent fractures occur significantly sooner, AJNR Am. J. Neuroradiol. 27 (2006), 217-223. (Pubitemid 46939916)
12. W.-J. Chen, Y.-H. Kao, S.-C. Yang, S.-W. Yu, Y.-K. Tu and K.-C. Chung, Impact of cement leakage into disks on the development of adjacent vertebral compression fractures, Journal of Spinal Disorders & Techniques 23 (2010), 35-39.
13. G. Baroud, P. Heini, J. Nemes, M. Bohner, S. Ferguson and T. Steffen, Biomechanical explanation of adjacent fractures following vertebroplasty letter, Radiology 229 (2003), 606-608 Radiology 229 (2003), 606-608. (Pubitemid 37310856)
14. G. Baroud, J. Nemes, P. Heini and T. Steffen, Load shift of the intervertebral disc after a vertebroplasty: a finite-element study, European Spine Journal 12 (2003), 421-426. (Pubitemid 37108414)
15. U. Berlemann, S.J. Ferguson, L.-P. Nolte and P.F. Heini, Adjacent vertebral failure after vertebroplasty: a biomechanical investigation, J. Bone Joint Surg. Br. 84-B (2002), 748-752. (Pubitemid 34846392)
16. R.Wilcox, The biomechanical effect of vertebroplasty on the adjacent vertebral body: a finite element study, Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine 220 (2006), 565-572.
17. C.A.H. Klazen, A. Venmans, J. De Vries et al., Percutaneous vertebroplasty is not a risk factor for new osteoporotic compression fractures: results from VERTOS II, American Journal of Neuroradiology 31 (2010), 1447-1450.
18. A. Boger, P. Heini, M. Windolf and E. Schneider, Adjacent vertebral failure after vertebroplasty: a biomechanical study of low-modulus PMMA cement, European Spine Journal 16 (2007), 2118-2125. (Pubitemid 350276084)
19. A. Boger, A. Bisig, M. Bohner, P. Heini and E. Schneider, Variation of the mechanical properties of PMMA to suit osteoporotic cancellous bone, Journal of Biomaterials Science, Polymer Edition 19 (2008), 1125-1142.
20. S. Beck and A. Boger, Evaluation of the particle release of porous PMMA cements during curing, Acta Biomater. 5 (2009), 2503-2507.
21. W.M. Lam, H.B. Pan, M.K. Fong et al., In vitro characterization of low modulus linoleic acid coated strontium-substituted hydroxyapatite containing PMMA bone cement, Journal of Biomedical Materials Research Part B: Applied Biomaterials 96B (2010), 76-83.
22. D. Martinz and J. Quadros, Compounding PVC with renewable materials, Plastics, Rubber and Composites 37 (2008), 459-464.
23. T.R. Kukreja, R.C. Chauhan, S. Choe and P.P. Kundu, Effect of the doses and nature of vegetable oil on carbon black/rubber interactions: Studies on castor oil and other vegetable oils, Journal of Applied Polymer Science 87 (2003), 1574-1578. (Pubitemid 36103705)
24. P. Raju, V. Nandanan and S.K.N. Kutty, A study on the use of castor oil as plasticizer in natura rubber compounds, Progress in Rubber, Plastics and Recycling Technology 23 (2007), 169-180. (Pubitemid 47186784)
25. Final report on the safety assessment of Ricinus communis (castor) seed oil, hydrogenated castor oil, glyceryl ricinoleate, glyceryl ricinoleate se, ricinoleic acid, potassium ricinoleate, sodium ricinoleate, zinc ricinoleate, cetyl ricinoleate, ethyl ricinoleate, glycol ricinoleate, isopropyl ricinoleate, methyl ricinoleate, and octyldodecyl ricinoleate, International Journal of Toxicology 26 (2007), 31-77.
26. V. Sharma and P.P. Kundu, Addition polymers from natural oils - a review, Progress in Polymer Science 31 (2006), 983-1008. (Pubitemid 44738011)
27. ASTM F451-08, ASTM International, West Conshohocken, PA, USA, 2008.
28. D.F. Farrar and J. Rose, Rheological properties of PMMA bone cements during curing, Biomaterials 22 (2001), 3005- 3013. (Pubitemid 32768708)
29. ISO-10993, ISO, 2001.
30. R.A. Eriksson and T. Albrektsson, The effect of heat on bone regeneration: An experimental study in the rabbit using the bone growth chamber, Journal of Oral and Maxillofacial Surgery 42 (1984), 705-711. (Pubitemid 15215826)
31. R.A. Eriksson, T. Albrektsson and B. Magnusson, Assessment of bone viability after heat trauma: a histological, histochemical and vital microscopic study in the rabbit, Journal of Plastic and Reconstructive Surgery and Hand Surgery 18 (1984), 261-268. (Pubitemid 15167563)
32. R. Schmidt, B. Cakir, T. Mattes, M. Wegener, W. Puhl and M. Richter, Cement leakage during vertebroplasty: an underestimated problem?, European Spine Journal 14 (2005), 466-473. (Pubitemid 40922194)
33. R. Lador, N. Dreiangel, P.J. Ben-Galim and J.A. Hipp, A pictorial classification atlas of cement extravasation with vertebral augmentation, The Spine Journal 10 (2010), 1118-1127.
34. M. Loeffel, S.J. Ferguson, L.-P. Nolte and J.H. Kowal, Vertebroplasty: experimental characterization of polymethylmethacrylate bone cement spreading as a function of viscosity, bone porosity, and flow rate, Spine 33 (2008), 1352-1359.