A tissue-engineered bioabsorbable nerve conduit created by three-dimensional culture of induced pluripotent stem cell-derived neurospheres

Bio-Medical Materials and Engineering

Volumn 21, Issue 5-6, 2011, Pages 333-339

  Uemura, Takuya ^a   Takamatsu, Kiyohito ^b   Ikeda, Mikinori ^a   Okada, Mitsuhiro ^a   Kazuki, Kenichi ^b   Ikada, Yoshito ^c   Nakamura, Hiroaki ^a  

^a OSAKA CITY UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b OSAKA CITY GENERAL HOSPITAL   (Japan)

^c NARA MEDICAL UNIVERSITY   (Japan)

Author keywords

induced pluripotent stem cells; Nerve conduits; peripheral nerve; regenerative medicine; tissue engineering

Indexed keywords

BIOABSORBABLE; BIOABSORBABLE POLYMER; CAPROLACTONE; GLIAL CELLS; IMMUNOHISTOCHEMISTRY; IN-VITRO; INNER SURFACES; L-LACTIDE; NERVE CONDUITS; NEUROSPHERES; PERIPHERAL NERVES; PLURIPOTENT; PLURIPOTENT STEM CELLS; REGENERATIVE MEDICINE; SCHWANN CELLS; THREE-DIMENSIONAL CULTURE;

CELL CULTURE; NEURONS; STEM CELLS; THREE DIMENSIONAL; TISSUE; TISSUE ENGINEERING;

SCAFFOLDS (BIOLOGY);

IPS;

POLYMER; TISSUE SCAFFOLD;

ARTICLE; BIODEGRADABLE IMPLANT; CELL CULTURE; CELL DIFFERENTIATION; CHEMISTRY; CULTURE TECHNIQUE; CYTOLOGY; DRUG EFFECT; EVALUATION; HUMAN; INSTRUMENTATION; METHODOLOGY; MULTICELLULAR SPHEROID; NERVE CELL; NERVE REGENERATION; PHYSIOLOGY; PLURIPOTENT STEM CELL; POROSITY; TISSUE ENGINEERING; TISSUE REGENERATION;

ABSORBABLE IMPLANTS; CELL CULTURE TECHNIQUES; CELL DIFFERENTIATION; CELLS, CULTURED; GUIDED TISSUE REGENERATION; HUMANS; INDUCED PLURIPOTENT STEM CELLS; NERVE REGENERATION; NEURONS; POLYMERS; POROSITY; SPHEROIDS, CELLULAR; TISSUE ENGINEERING; TISSUE SCAFFOLDS;

EID: 84861398650     PISSN: 09592989     EISSN: None     Source Type: Journal    
DOI: 10.3233/BME-2012-0680     Document Type: Article

References (30)

1. J. Isaacs, Treatment of acute peripheral nerve injuries: current concepts, J. Hand. Surg. Am. 35 (2010), 491-497.
2. A. Pabari, S.Y. Yang, A.M. Seifalian and A. Mosahebi, Modern surgical management of peripheral nerve gap, J. Plast. Reconstr. Aesthet. Surg. 63 (2010), 1941-1948.
3. L.B. Dahlin and G. Lundborg, Use of tubes in peripheral nerve repair, Neurosurg. Clin. N. Am. 12 (2001), 341-352. (Pubitemid 32397174)
4. X. Jiang, S.H. Lim, H.Q. Mao and S.Y. Chew, Current applications and future perspectives of artificial nerve conduits, Exp. Neurol. 223 (2010), 86-101.
5. G.C. de Ruiter, M.J. Malessy, M.J. Yaszemski, A.J. Windebank and R.J. Spinner, Designing ideal conduits for peripheral nerve repair, Neurosurg. Focus. 26 (2009), E5.
6. B. Battiston, P. Tos, T.R. Cushway and S. Geuna, Nerve repair by means of vein filled with muscle grafts I. Clinical results, Microsurgery 20 (2000), 32-36. (Pubitemid 30053971)
7. G. Lundborg, L.B. Dahlin, N. Danielsen, R.H. Gelberman, F.M. Longo, H.C. Powell and S. Varon, Nerve regeneration in silicone chambers: influence of gap length and of distal stump components, Exp. Neurol. 76 (1982), 361-375. (Pubitemid 12112361)
8. M. Koshimune, K. Takamatsu, H. Nakatsuka, K. Inui, Y. Yamano and Y. Ikada, Creating bioabsorbable Schwann cell coated conduits through tissue engineering, Biomed. Mater. Eng. 13 (2003), 223-229. (Pubitemid 37039709)
9. V. Guénard, N. Kleitman, T.K. Morrissey, R.P. Bunge and P. Aebischer, Syngeneic Schwann cells derived from adult nerves seeded in semipermeable guidance channels enhance peripheral nerve regeneration, J. Neurosci. 12 (1992), 3310- 3320.
10. T. Hadlock, C. Sundback, D. Hunter, M. Cheney and J.P. Vacanti, A polymer foam conduit seeded with Schwann cells promotes guided peripheral nerve regeneration, Tissue. Eng. 6 (2000), 119-127. (Pubitemid 30227168)
11. K. Takahashi and S. Yamanaka, Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors, Cell 126 (2006), 663-676. (Pubitemid 44233629)
12. K. Okita, T. Ichisaka and S. Yamanaka, Generation of germline-competent induced pluripotent stem cells, Nature 448 (2007), 313-317. (Pubitemid 47080336)
13. K. Miura, Y. Okada, T. Aoi, A. Okada, K. Takahashi, K. Okita, M. Nakagawa, M. Koyanagi, K. Tanabe, M. Ohnuki, D. Ogawa, E. Ikeda, H. Okano and S. Yamanaka, Variation in the safety of induced pluripotent stem cell lines, Nat. Biotechnol. 27 (2009), 743-745.
14. Y. Okada, A. Matsumoto, T. Shimazaki, R. Enoki, A. Koizumi, S. Ishii, Y. Itoyama, G. Sobue and H. Okano, Spatiotemporal recapitulation of central nervous system development by murine embryonic stem cell-derived neural stem/progenitor cells, Stem. Cells 26 (2008), 3086-3098.
15. M. Nakagawa,M. Koyanagi, K. Tanabe, K. Takahashi, T. Ichisaka, T. Aoi, K. Okita, Y.Mochiduki, N. Takizawa and S. Yamanaka, Generation of induced pluripotent stem cells without Myc from mouse and human fibroblasts, Nat. Biotechnol. 26 (2008), 101-106.
16. F. Sun, K. Zhou, W.J. Mi and J.H. Qiu, Combined use of decellularized allogeneic artery conduits with autologous transdifferentiated adipose-derived stem cells for facial nerve regeneration in rats, Biomaterials 32 (2011), 8118-8128.
17. H. Lin, F. Liu, C. Zhang, Z. Zhang, Z. Kong, X. Zhang and R.M. Hoffman, Characterization of nerve conduits seeded with neurons and Schwann cells derived from hair follicle neural crest stem cells, Tissue. Eng. Part A 17 (2011), 1691-1698.
18. Q. Ao, C.K. Fung, A.Y. Tsui, S. Cai, H.C. Zuo, Y.S. Chan and D.K. Shum, The regeneration of transected sciatic nerves of adult rats using chitosan nerve conduits seeded with bone marrow stromal cell-derived Schwann cells, Biomaterials 32 (2011), 787-796.
19. L. Cui, J. Jiang, L. Wei, X. Zhou, J.L. Fraser, B.J. Snider and S.P. Yu, Transplantation of embryonic stem cells improves nerve repair and functional recovery after severe sciatic nerve axotomy in rats, Stem. Cells 26 (2008), 1356-1365.
20. C. Marchesi, M. Pluderi, F. Colleoni, M. Belicchi, M. Meregalli, A. Farini, D. Parolini, L. Draghi, M.E. Fruguglietti, M. Gavina, L. Porretti, A. Cattaneo, M. Battistelli, A. Prelle, M. Moggio, S. Borsa, L. Bello, D. Spagnoli, S.M. Gaini, M.C. Tanzi, N. Bresolin, N. Grimoldi and Y. Torrente, Skin-derived stem cells transplanted into resorbable guides provide functional nerve regeneration after sciatic nerve resection, Glia 55 (2007), 425-438.
21. L. Zheng and H.F. Cui, Use of chitosan conduit combined with bone marrow mesenchymal stem cells for promoting peripheral nerve regeneration, J. Mater. Sci. Mater. Med. 21 (2010), 1713-1720.
22. K.H. Tse, M. Sun, C. Mantovani, G. Terenghi, S. Downes and P.J. Kingham, In vitro evaluation of polyester-based scaffolds seeded with adipose derived stem cells for peripheral nerve regeneration, J. Biomed. Mater. Res. A 95 (2010), 701-708.
23. X. Wang, E. Luo, Y. Li and J. Hu, Schwann-like mesenchymal stem cells within vein graft facilitate facial nerve regeneration and remyelination, Brain. Res. 1383 (2011), 71-80.
24. G. Liu, Y. Cheng, S. Guo, Y. Feng, Q. Li, H. Jia, Y. Wang, L. Tong and X. Tong, Transplantation of adipose-derived stem cells for peripheral nerve repair, Int. J. Mol. Med. 28 (2011), 565-572.
25. A. Wang, Z. Tang, I.H. Park, Y. Zhu, S. Patel, G.Q. Daley and S. Li, Induced pluripotent stem cells for neural tissue engineering, Biomaterials 32 (2011), 5023-5032.
26. R.H. Shin, P.F. Friedrich, B.A. Crum, A.T. Bishop and A.Y. Shin, Treatment of a segmental nerve defect in the rat with use of bioabsorbable synthetic nerve conduits: a comparison of commercially available conduits, J. Bone. Joint. Surg. Am. 91 (2009), 2194-2204.
27. Y. Okada, T. Shimazaki, G. Sobue and H. Okano, Retinoic-acid- concentration-dependent acquisition of neural cell identity during in vitro differentiation of mouse embryonic stem cells, Dev. Biol. 275 (2004), 124-142. (Pubitemid 39302616)
28. G. Kumagai, Y. Okada, J. Yamane, N. Nagoshi, K. Kitamura, M. Mukaino, O. Tsuji, K. Fujiyoshi, H. Katoh, S. Okada, S. Shibata, Y. Matsuzaki, S. Toh, Y. Toyama, M. Nakamura and H. Okano, Roles of ES cell-derived gliogenic neural stem/progenitor cells in functional recovery after spinal cord injury, PLoS One 4 (2009), e7706.
29. O. Tsuji, K. Miura, Y. Okada, K. Fujiyoshi,M.Mukaino, N. Nagoshi, K. Kitamura, G. Kumagai,M. Nishino, S. Tomisato, H. Higashi, T. Nagai, H. Katoh, K. Kohda, Y. Matsuzaki, M. Yuzaki, E. Ikeda, Y. Toyama, M. Nakamura, S. Yamanaka and H. Okano, Therapeutic potential of appropriately evaluated safe-induced pluripotent stem cells for spinal cord injury, Proc. Natl. Acad. Sci. USA 107 (2010), 12704-12709.
30. M. Wernig, A. Meissner, J.P. Cassady and R. Jaenisch, c-Myc is dispensable for direct reprogramming of mouse fibroblasts, Cell. Stem. Cell. 2 (2008), 10-12.