Somatic mutation of STAG2, an aneuploidy-related gene, is rare in acute leukemias

Leukemia and Lymphoma

Volumn 53, Issue 6, 2012, Pages 1234-1235

  Chung, Nak Gyun ^a   Kim, Min Sung ^a   Yoo, Nam Jin ^a   Lee, Sug Hyung ^a  

^a The Catholic University of Korea   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

ACUTE GRANULOCYTIC LEUKEMIA; ACUTE LEUKEMIA; ACUTE LYMPHOBLASTIC LEUKEMIA; ALLELE; ANEUPLOIDY; GENE; HUMAN; LETTER; PRIORITY JOURNAL; SOMATIC MUTATION; STAG2 GENE;

ACUTE DISEASE; ADULT; AGE OF ONSET; ANEUPLOIDY; ANTIGENS, NUCLEAR; ASIAN CONTINENTAL ANCESTRY GROUP; CASE-CONTROL STUDIES; CHILD; DNA MUTATIONAL ANALYSIS; GENE FREQUENCY; HUMANS; LEUKEMIA; MUTATION; REPUBLIC OF KOREA;

EID: 84861386930     PISSN: 10428194     EISSN: 10292403     Source Type: Journal    
DOI: 10.3109/10428194.2011.645819     Document Type: Letter

References (5)

1. Holland AJ, Cleveland DW. Boveri revisited: chromosomal instability, aneuploidy and tumorigenesis. Nat Rev Mol Cell Biol 2009;10:478-487.
2. Solomon DA, Kim T, Diaz-Martinez LA, et al. Mutational inactivation of STAG2 causes aneuploidy in human cancer. Science 2011;333:1039-1043.
3. Walter MJ, Payton JE, Ries RE, et al. Acquired copy number alterations in adult acute myeloid leukemia genomes. Proc Natl Acad Sci USA 2009;106:12950-12955.
4. Rocquain J, Gelsi-Boyer V, Adélaïde J, et al. Alteration of cohesion genes in myeloid diseases. Am J Hematol 2010;85:717-719.
5. Lee JW, Soung YH, Kim SY, et al. PIK3CA gene is frequently mutated in breast carcinomas and hepatocellular carcinomas. Oncogene 2005;24:1477-1480. (Pubitemid 40343128)