Effects of peroxisome proliferator-activated receptor-γ agonists on the generation of microparticles by monocytes/macrophages

Cardiovascular Research

Volumn 94, Issue 3, 2012, Pages 537-544

  Neri, Tommaso ^a   Cordazzo, Cinzia ^a   Carmazzi, Yuri ^a   Petrini, Silvia ^a   Bala, Cristina ^a   Stefanelli, Fabio ^a   Amoruso, Angela ^b   Brunelleschi, Sandra ^b   Breschi, Maria Cristina ^a   Pedrinelli, Roberto ^a   Paggiaro, Pierluigi ^a   Celi, Alessandro ^a  

^a UNIVERSITY OF PISA   (Italy)

^b UNIVERSITY OF EASTERN PIEDMONT   (Italy)

Author keywords

Extracellular signal regulated kinase activation; Microparticles; Monocyte macrophage; Peroxisome proliferator activated receptor ; Thrombosis

Indexed keywords

15 DEOXY DELTA12,14 PROSTAGLANDIN J2; 2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 2 CHLORO 5 NITROBENZANILIDE; BLOOD CLOTTING FACTOR 10A; CALCIUM ION; EGTAZIC ACID; FLUORESCENT DYE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PHOSPHATIDYLSERINE; PIOGLITAZONE; ROSIGLITAZONE; THROMBOPLASTIN;

ARTICLE; BLOOD CLOTTING; CALCIUM CELL LEVEL; CALCIUM MOBILIZATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG EFFECT; ENZYME PHOSPHORYLATION; HUMAN; HUMAN CELL; MACROPHAGE; MEMBRANE MICROPARTICLE; MICROPARTICLE ENZYME IMMUNOASSAY; MONOCYTE; NORMAL HUMAN; PRIORITY JOURNAL; THROMBOCYTE; WESTERN BLOTTING;

APOPTOSIS; CELL-DERIVED MICROPARTICLES; CELLS, CULTURED; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; HUMANS; MACROPHAGES; MITOGEN-ACTIVATED PROTEIN KINASES; MONOCYTES; PPAR GAMMA; SIGNAL TRANSDUCTION; THIAZOLIDINEDIONES;

EID: 84861372961     PISSN: 00086363     EISSN: 17553245     Source Type: Journal    
DOI: 10.1093/cvr/cvs125     Document Type: Article

References (37)

1. Hugel B, Martinez MC, Kunzelmann C, Freyssinet JM. Membrane microparticles: two sides of the coin. Physiology (Bethesda) 2005;20:22-27. (Pubitemid 40363367)
2. Ardoin SP, Shanahan JC, Pisetsky DS. The role of microparticles in inflammation and thrombosis. Scand J Immunol 2007;66:159-165. (Pubitemid 47063209)
3. Distler JHW, Distler O. Inflammation: microparticles and their roles in inflammatory arthritides. 2010;6:385-386.
4. Morel O, Toti F, Hugel B, Bakouboula B, Camoin-Jau L, Dignat-George F et al. Procoagulant microparticles: disrupting the vascular homeostasis equation? Arterioscler Thromb Vasc Biol 2006;26:2594-2604.
5. Leroyer AS, Anfosso F, Lacroix R, Sabatier F, Simoncini S, Njock SM et al. Endothelialderived microparticles: biological conveyors at the crossroad of inflammation, thrombosis and angiogenesis. Thromb Haemost 2010;104:456-463.
6. Furie B, Furie BC. Molecular and cellular biology of blood coagulation. N Engl J Med 1992;326:800-806.
7. Sims PJ, Wiedmer T, Esmon CT, Weiss HJ, Shattil SJ. Assembly of the platelet prothrombinase complex is linked to vesiculation of the platelet plasma membrane. Studies in Scott syndrome: an isolated defect in platelet procoagulant activity. J Biol Chem 1989;264:17049-17057. (Pubitemid 19255533)
8. Furie B. Pathogenesis of thrombosis. Hematology Am Soc Hematol Educ Program 2009; 2009:255-258.
9. Satta N, Toti F, Feugeas O, Bohbot A, Dachary-Prigent J, Eschwege V et al. Monocyte vesiculation is a possible mechanism for dissemination of membrane-associated procoagulant activities and adhesion molecules after stimulation by lipopolysaccharide. J Immunol 1994;153:3245-3255. (Pubitemid 24292551)
10. Lechner D, Weltermann A. Circulating tissue factor-exposing microparticles. Thromb Res 2008;122(Suppl. 1):S47-S54.
11. Nemerson Y. Tissue factor and hemostasis. Blood 1988;71:1-8. (Pubitemid 18050383)
12. Giesen PLA, Rauch U, Bohrmann B, Kling D, Roque M, Fallon JT et al. Blood-borne tissue factor: another view of thrombosis. Proc Natl Acad Sci USA 1999;96:2311-2315. (Pubitemid 29117911)
13. Mackman N, Tilley RE, Key NS. Role of the extrinsic pathway of blood coagulation in hemostasis and thrombosis. Arterioscler Thromb Vasc Biol 2007;27:1687-1693. (Pubitemid 47207163)
14. Falati S, Liu Q, Gross P, Merrill-Skoloff G, Chou J, Vandendries E et al. Accumulation of tissue factor into developing thrombi in vivo is dependent upon microparticle Pselectin glycoprotein ligand 1 and platelet P-selectin. J Exp Med 2003;197:1585-1598. (Pubitemid 36682554)
15. Celi A, Lorenzet R, Furie BC, Furie B. Microparticles and a P-selectin-mediated pathway of blood coagulation. Dis Markers 2004;20:347-352. (Pubitemid 40392421)
16. Mallat Z, Benamer H, Hugel B, Benessiano J, Steg PG, Freyssinet J-M et al. elevated levels of shed membrane microparticles with procoagulant potential in the peripheral circulating blood of patients with acute coronary syndromes. Circulation 2000;101:841-843. (Pubitemid 30117876)
17. Boulanger CM, Amabile N, Tedgui A. Circulating microparticles: a potential prognostic marker for atherosclerotic vascular disease. Hypertension 2006;48:180-186. (Pubitemid 44309805)
18. VanWijk MJ, VanBavel E, Sturk A, Nieuwland R. Microparticles in cardiovascular diseases. Cardiovasc Res 2003;59:277-287. (Pubitemid 37272022)
19. Pasquet JM, Dachary-Prigent J, Nurden AT. Calcium influx is a determining factor of calpain activation and microparticle formation in platelets. Eur J Biochem 1996;239: 647-654. (Pubitemid 26253036)
20. Semple RK, Chatterjee VK, O'Rahilly S. PPARg and human metabolic disease. J Clin Invest 2006;116:581-589.
21. http://www.fda.gov/Safety/MedWatch/SafetyInformation/ SafetyAlertsforHumanMedicalProducts/ucm226994.htm (4 July 2011).
22. http://www.ema.europa.eu/ema/index.jsp?curl=pages/medicines/human/ public-health-alerts/2010/09/human-pha-detail-000020.jsp&murl=menus/ medicines/medicines.jsp&mid=WC0b01ac058001d126&source= homeMedSearch&category=human (4 July 2011).
23. Nissen SE, Wolski K. Effect of rosiglitazone on the risk of myocardial infarction and death from cardiovascular causes. N Engl J Med 2007;356:2457-2471. (Pubitemid 46919772)
24. Singh N, Webb R, Adams R, Evans SA, Al-Mosawi A, Evans M et al. The PPAR-g activator, Rosiglitazone, inhibits actin polymerisation in monocytes: involvement of Akt and intracellular calcium. Biochem Biophys Res Commun 2005;333:455-462. (Pubitemid 40848313)
25. Cerri C, Chimenti D, Conti I, Neri T, Paggiaro P, Celi A. Monocyte/macrophagederived microparticles up-regulate inflammatory mediator synthesis by human airway epithelial cells. J Immunol 2006;177:1975-1980. (Pubitemid 44092538)
26. Celi A, Pellegrini G, Lorenzet R, Blasi AD, Ready N, Furie BC et al. P-selectin induces the expression of tissue factor on monocytes. Proc Natl Acad Sci USA 1994;91:8767-8771.
27. Di Stefano R, Barsotti MC, Armani C, Santoni T, Lorenzet R, Balbarini A et al. Human peripheral blood endothelial progenitor cells synthesize and express functionally active tissue factor. Thromb Res 2009;123:925-930.
28. Laemmli UK. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 1970;227:680-685.
29. Galli A, Ceni E, Crabb DW, Mello T, Salzano R, Grappone C et al. Antidiabetic thiazolidinediones inhibit invasiveness of pancreatic cancer cells via PPARg independent mechanisms. Gut 2004;53:1688-1697. (Pubitemid 39434116)
30. Derlacz RA, Hyc K, Usarek M, Jagielski AK, Drozak J, Jarzyna R. PPAR-g-independent inhibitory effect of rosiglitazone on glucose synthesis in primary cultured rabbit kidney-cortex tubules. Biochem Cell Biol 2008;86:396-404.
31. Mughal RS, Warburton P, O'Regan DJ, Ball SG, Turner NA, Porter KE. Peroxisome proliferator-activated receptor gamma-independent effects of thiazolidinediones on human cardiac myofibroblast function. Clin Exp Pharmacol Physiol 2009;36:478-486.
32. Huang WC, Chio CC, Chi KH, Wu HM, Lin WW. Superoxide anion-dependent Raf/MEK/ERK activation by peroxisome proliferator activated receptor g agonists 15-deoxy-D12,14-prostaglandin J2, ciglitazone, and GW1929. Exp Cell Res 2002;277: 192-200.
33. Cauwenberghs S, Feijge MA, Harper AG, Sage SO, Curvers J, Heemskerk JW. Shedding of procoagulant microparticles from unstimulated platelets by integrin-mediated destabilization of actin cytoskeleton. FEBS Lett 2006;580:5313-5320. (Pubitemid 44415813)
34. Li M, Yu D, Williams KJ, Liu ML. Tobacco smoke induces the generation of procoagulant microvesicles from human monocytes/macrophages. Arterioscler Thromb Vasc Biol 2010;30:1818-1824.
35. Franklin RA, Atherfold PA, McCubrey JA. Calcium-induced ERK activation in human T lymphocytes occurs via p56(Lck) and CaM-kinase. Mol Immunol 2000;37:675-683. (Pubitemid 32112655)
36. Montiel M, Quesada J, Jimenez E. Activation of calcium-dependent kinases and epidermal growth factor receptor regulate muscarinic acetylcholine receptor-mediated MAPK/ERK activation in thyroid epithelial cells. Cell Signal 2007;19:2138-2146. (Pubitemid 47353816)
37. Majeed Y, Bahnasi Y, Seymour VAL, Wilson LA, Milligan CJ, Agarwal AK et al. Rapid and contrasting effects of rosiglitazone on transient receptor potential TRPM3 and TRPC channels. Mol Pharmacol 2011;79:1023-1030.