Antiepileptic drugs and suicide

The Neuropsychiatry of Epilepsy, Second Edition

Volumn , Issue , 2011, Pages 143-152

  Trimble, Michael R ^a  

^a NONE

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EID: 84861357033     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1017/CBO9780511977145.014     Document Type: Chapter

References (58)

1. Andersohn F, Schade R, Willich SN, Garbe E (2010) Use of antiepileptic drugs in epilepsy and the risk of self-harm or suicidal behavior. Neurology, 75, 335-340.
2. Arana A, Wentworth CE, Ayuso-Mateos JL, Arellano FM (2010) Suicide-related events in patients treated with antiepileptic drugs. The New England Journal of Medicine, 363, 542-551.
3. Barraclough B (1981) Suicide and epilepsy. In: Reynolds EH, Trimble MR (eds) Epilepsy and Psychiatry. Churchill Livingstone, Edinburgh, pp. 72-76.
4. Bell GS, Mula M, Sander JW (2009) Suicidality in people taking antiepileptic drugs. CNS Drugs, 23, 281-292.
5. Ben-Menachem E, Persson LI, Hedner T (1992) Selected CSF biochemistry and Gabapentin concentrations in the CSF and plasma in patients with partial seizures after a single oral dose of Gabapentin. Epilepsy Research, 11, 45-49.
6. Ben-Menachem E, Söderfelt B, Hamberger A, et al. (1995) Seizure frequency and CSF parameters in a double-blind placebo controlled trial of gabapentin in patients with intractable complex partial seizures. Epilepsy Research, 21, 231-236.
7. Berrettini WH, Nurnburger JI, Hare TA, et al. (1983) Reduced plasma and CSF GABA in affective illness: effect of lithium carbonate. Biological Psychiatry, 18, 185-194.
8. Bertrand S, Ng GYK, Purisai MG, et al. (2001) The anticonvulsant, antihyperalgesic agent gabapentin is an agonist at brain GABA type B receptors negatively coupled to voltage dependent calcium channels. Journal of Pharmacology and Experimental Therapeutics, 298, 15-24.
9. Blumer D (2004) Epilepsy and suicide. In: Trimble MR, Schmitz B (eds) The Neuropsychiatry of Epilepsy. Cambridge University Press, Cambridge, pp. 107-116.
10. Bowery NG (1997) Pharmacology of mammalian GABAb receptors. In: Enna SJ, Bowery NG (eds) The GABA Receptors. Humana Press, New Jersey.
11. Brent DA (1986) Over representation of epileptics in a consecutive series of suicide attempts seen at a children’s hospital, 1978-1983. Journal of the American Academy of Child Psychiatry, 25, 242-246.
12. Cardenas JF, Rho JM, Ng YT (2010) Reversible lamotrigine- induced neurobehavioral disturbances in children with epilepsy. Journal of Child Neurology, 25(2), 182-187.
13. Christensen J, Vestergaard M, Mortensen PB, et al. (2007) Epilepsy and risk of suicide: a population- based case-control study. Lancet Neurology, 6(8), 693-698.
14. Collins JC, McFarland BH (2008) Divalproex, lithium, and suicide among medicaid patients with bipolar disorder. Journal of Affective Disorders, 107, 23-28.
15. Cugley AL, Swartz BE (1995) Gabapentin-associated mood changes. Epilepsia, 36 (Suppl 4), 3.61.
16. Faubion MD, Christman DS (2007) Suicide attempts following initiation of topiramate. American Journal of Psychiatry, 164, 682-683.
17. FDA, US Department of Health and Human Services (2008) Statistical review and evaluation: antiepileptic drugs and suicidality, 23 May, 2008, Washington, p. 24.
18. Gibbons RD, Hur K, Brown H, Mann J (2009) Relationship between antiepileptic drugs and suicide attempts in patients with bipolar disorder. Archives of General Psychiatry, 66, 1354-1360.
19. Goodwin FK, Fireman B, Simon GE, et al. (2003) Suicide risk in bipolar disorder during treatment with lithium and divalproex. JAMA, 290, 1467-1473.
20. Gotz TJ, Fuerstein A, Lais A, Meyer D (1993) Effects of gabapentin on release of GABA from slices of rat neostriatum. Arzneim-Forschung 43, 636-638.
21. Gomer B, Wagner K, Frings L, et al. (2010) The influence of antiepileptic drugs on cognition: a comparison of leveteracetam with topiramate. Epilepsy and Behaviour, 10, 486-494.
22. Gryder DS, Rogawski MA, (2003) Selective anatagonism of GluR5 kainate-receptor-mediated synaptic currents by topiramate in rat basolateral amygdala neurones. Journal of Neuroscience, 23, 7069-7074.
23. Hawton K, Fagg J, Marsack P (1980) Association between epilepsy and attempted suicide. Journal of Neurology and Neurosurgery and Psychiatry, 43, 168-170.
24. Hesdorffer DC, Kanner AM (2009) The FDA alert on suicidality and antiepileptic drugs: fire or false alarm. Epilepsia, 50, 978-986.
25. Hesdorffer DC, Hauser WA, Olafsson E, et al. (2006) Depression and suicide attempt as risk factors for incident unprovoked seizures. Annals of Neurology, 59(1), 35-41.
26. Honmou O, Kocsis JD, Richerson GB (1995) Gabapentin potentiates the conductance increase induced by nipecotic acid in CA1 pyramidal neurons in vitro. Epilepsy Research, 20, 193-202.
27. Jansen JFA, Aldenkamp AP, Marian Majoie HJ, et al. (2006) Functional MRI reveals declined prefrontal cortex activation in patients with epilepsy on topiramate therapy. Epilepsy and Behaviour, 2006, 9, 181-185.
28. Kalinin VV, Polyanskiy DA (2005) Gender and suicidality prediction in epilepsy. Epilepsy and Behaviour, 7, 657-663.
29. Kanemoto K, Kawasaki J, Kawai I (1996) Postictal psychosis: a comparison with acute interictal and chronic psychoses. Epilepsia, 37, 551-556.
30. Keele NB (2005) The role of serotonin in impulsive and aggressive behaviors associated with epilepsy-like neuronal hyperexcitability in the amygdala. Epilepsy and Behavior, 7, 325-335.
31. Kuzniecky R, Pan J, Martin R, et al. (2002) Modulation of cerebral GABA by topiramate, lamotrigine and gabapentin in healthy adults. Neurology, 58, 368-372.
32. Levinson DF, Devinsky O (1999) Psychiatric adverse events during vigabatrin therapy. Neurology, 53(7), 1503-1511.
33. Loescher W, Hoenack D, Taylor CP (1991) Gabapentin increases aminooxyacetic acid induced GABA accumulation in several regions of rat brain. Neuroscience Letters, 128, 150-154.
34. Mann JJ, Malone KM (1997) Cerebrospinal fluid amines and higher-lethality suicide attempts in depressed in-patients. Biological Psychiatry, 41, 162-171.
35. Mehlman PT, Higley JD, Faucher I, et al. (1994) Low CSF 5-HIAA concentrations and severe aggression and impaired impulse control in non-human primates. American Journal of Psychiatry, 151, 1485-1491.
36. Miczek KA, Altman JL, Appel JB, Boggan WO (1975) para-chlorophenylalanine, serotonin, and killing behavior. Pharmacology, Biochemistry and Behavior, 3, 355-361.
37. Mula M, Trimble MR, Lhatto SD, Sander JWAS (2003a) Topiramate and psychiatric adverse events in patients with epilepsy. Epilepsia, 44, 456-463.
38. Mula M, Trimble MR, Thompson P, et al. (2003b) Topiramate and word finding difficulties in patients with epilepsy. Neurology, 60, 1104-1107.
39. Mula M, Trimble MR, Yuen A, et al. (2003c) Psychiatric adverse events during levetiracetam therapy. Neurology, 61, 704-706.
40. Mula M, Sander JW (2007a) Negative effects of antiepileptic drugs on mood in patients with epilepsy. Drug Safety, 30, 555-567.
41. Mula M, Sander JW (2007b) Suicidal ideation in epilepsy and levetiracetam therapy. Epilepsy and Behaviour, 11, 130-132.
42. Nishikawa T, Scatton B (1983) Evidence for a GABAergic inhibitory influence on serotonergic neurons originating from the dorsal raphe. Brain Research, 279, 325-329.
43. Olesen JB, Hansen PR, Erdal J, et al. (2010) Antiepileptic drugs and the risk of suicide: a nationwide study. Pharmacoepidemiology and Drug Safety, 19(5), 518-524.
44. Parker DAS, Ong J, Marino V, Kerr DIB (2004) Gabapentin activates presynaptic GABAb heteroreceptors in rat cortical slices. European Journal of Pharmacology, 495, 137-143.
45. Patorno E, Bohn RL, Wahl PM, et al. (2010) Anticonvulsant medications and risk of suicide, attempted suicide or violent death. JAMA, 303, 1401-1409.
46. Petroff OA, Hyder F, Mattson RH, Rothman DL (1999) Topiramate increases brain GABA, homocarnisine and pyrrolidinone in patients with epilepsy. Neurology, 52, 473-478.
47. Petroff OA, Hyder F, Rothman DL, Mattson RH (2000a) Effects of Gabapentin on brain GABA, homocarnosine and pyrrolidinone in epilepsy patients. Epilepsia, 41, 675-680.
48. Petroff OA, Mattson RH, Rothman DL (2000b) Proton MRS: GABA and glutamate. Advances in Neurology, 83, 261-271. Review.
49. Petty F (1995) GABA and mood disorders: a brief review and hypothesis. Journal of Affective Disorders, 34, 275-281.
50. Ring HA, Crellin R, Kirker S, Reynolds EH (1993) Vigabatrin and depression. Journal of Neurology, Neurosurgery and Psychiatry, 56(8), 925-928.
51. Sanacora G, Gueorguieva R, Epperson CN, et al. (2004) Sub-type specific alterations of GABA and glutamate in major depression. Archives of General Psychiatry, 62, 705-713.
52. Schmitz B (2002) The effects of antiepileptic drugs on behavior. In: Trimble M and Schmitz B (eds) The Neuropsychiatry of Epilepsy. Cambridge University Press, Cambridge, pp. 241-255.
53. Schmitz B (2006) Effects of antiepileptic drugs on mood and behaviour. Epilepsia, 47 (Suppl 2), 28-33.
54. Sills GJ (2006) The mechanisms of action of gabapentin and pregabalin. Current Opinion in Pharmacology, 6, 108-113.
55. Stanley B, Molcho A, Stanley M, et al. (2000) Association of aggressive behavior with altered serotonergic function in patients who are not suicidal. American Journal of Psychiatry, 157, 609-614.
56. Stanley M, Mann JJ (1983) Increased serotonin-2 binding sites in frontal cortex of suicide victims. Lancet, i, 214-216.
57. Thomas L, Trimble MR, Schmitz B, Ring H (1996) Vigabatrin and behavior disorders: a retrospective survey. Epilepsy Research, 25, 21-27.
58. Trimble MR, George MS (2010) Biological Psychiatry, 3rd edn. Wiley-Blackwell, Oxford.