Incidence of tuberculosis and early mortality in a large cohort of HIV infected patients receiving antiretroviral therapy in a tertiary hospital in Addis Ababa, Ethiopia

Transactions of the Royal Society of Tropical Medicine and Hygiene

Volumn 106, Issue 6, 2012, Pages 363-370

  Kassa, Aragie ^a   Teka, Azmera ^b   Shewaamare, Aster ^c   Jerene, Degu ^d  

^a FEDERAL MINISTRY OF HEALTH   (Ethiopia)

^b Siba Consulting and Research Firm   (Ethiopia)

^c Zewdiu Memorial Hospital   (Ethiopia)

^d HIV/AIDS Prevention and Control Office   (Ethiopia)

Author keywords

CD4; HAART; HIV; TB; TB HIV; WHO clinical stage

Indexed keywords

EFAVIRENZ; LAMIVUDINE; NEVIRAPINE; STAVUDINE; TENOFOVIR DISOPROXIL;

ADOLESCENT; ADULT; ARTICLE; CD4+ T LYMPHOCYTE; COHORT ANALYSIS; CONTROLLED STUDY; DISEASE ASSOCIATION; DISEASE REGISTRY; EARLY MORTALITY; ETHIOPIA; FEMALE; HIGHLY ACTIVE ANTIRETROVIRAL THERAPY; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTED PATIENT; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; INCIDENCE; INFECTION RISK; LUNG TUBERCULOSIS; MAJOR CLINICAL STUDY; MALE; MEDICAL RECORD; MIXED INFECTION; PATIENT CARE; PATIENT INFORMATION; PATIENT MONITORING; RISK FACTOR; TERTIARY HEALTH CARE; TIME OF DEATH; TREATMENT DURATION; WORLD HEALTH ORGANIZATION;

ADULT; AIDS-RELATED OPPORTUNISTIC INFECTIONS; ANTI-HIV AGENTS; ANTIRETROVIRAL THERAPY, HIGHLY ACTIVE; CD4 LYMPHOCYTE COUNT; COHORT STUDIES; EARLY DIAGNOSIS; ETHIOPIA; FEMALE; HIV SEROPOSITIVITY; HOSPITAL MORTALITY; HUMANS; INCIDENCE; MALE; MIDDLE AGED; RETROSPECTIVE STUDIES; RISK FACTORS; TUBERCULOSIS;

EID: 84861340576     PISSN: 00359203     EISSN: 18783503     Source Type: Journal    
DOI: 10.1016/j.trstmh.2012.03.002     Document Type: Article

References (27)

1. Whalen C.C., Nsubuga P., Okwera A., et al. Impact of pulmonary tuberculosis on survival of HIV infected adults: a prospective epidemiologic study in Uganda. AIDS 2000, 14:1219-1228.
2. Badri M., Ehrilch R., Wood R., Pulerwitz T., Maartens G. Association between tuberculosis and HIV disease progression in a high tuberculosis prevalence area. Int J Tuber Lung Dis 2001, 5:225-232.
3. Gopal S., Horst C.V.D. Tuberculosis and HIV: dense macabre. AIDS 2010, 24:1953-1954.
4. Corbett E.L., Marston B., Churchyard G.J., Cock K.M.D. Tuberculosis in sub-Saharan Africa: opportunities, challenges, and change in the era of antiretroviral treatment. Lancet 2006, 367:926-937.
5. Badri M., Douglas W., Wood R. Effect of highly active antiretroviral therapy on incidence of tuberculosis in South Africa: a cohort study. Lancet 2002, 359:2059-2064.
6. Girardi E., Sabin C.A., Monforte A.D., et al. Incidence of tuberculosis among HIV-infected patients receiving highly active antiretroviral therapy in Europe and North America. Clin Infect Dis 2005, 41:1772-1782.
7. Lawn S.D., Motasim B., Wood R. Tuberculosis among HIV-infected patients receiving HAART: long term incidence and risk factors in a South African cohort. AIDS 2005, 19:2109-2116.
8. Moore D., Liechty C., Ekwaru P., et al. Prevalence, incidence and mortality associated with tuberculosis in HIV-infected patients initiating antiretroviral therapy in rural Uganda. AIDS 2007, 21:713-719.
9. Mocroft A., Ledergerber B., Katlama C., et al. Decline in the AIDS and death rates in the Euro SIDA study: an observational study. Lancet 2003, 362:22-29.
10. Komati S., Shaw P.A., Stubbs N., et al. Tuberculosis risk factors and mortality for HIV-infected persons receiving antiretroviral therapy in South Africa. AIDS 2010, 24:1849-1855.
11. Lawn S.D., Linda G.B., Wood R. How effectively does HAART restore immune responses to mycobacterium tuberculosis? Implications for tuberculosis control. AIDS 2005, 19:1113-1124.
12. Lopes G.S., Felix de Pinho A., Harrison L.H., Schechter M. Reduced risk of tuberculosis among Brazilian patients with advanced Human Immunodeficiency Virus infection treated with highly active antiretroviral therapy. Clin Infect Dis 2002, 34:543-546.
13. Grinsztejn B., Veloso V.G., Friedman R.K., et al. Early mortality and cause of deaths in patients using HAART in Brazil and the United States. AIDS 2009, 23:2107-2114.
14. Breen R.A.M., Smith C.J., Cropley I., Johnson M.A., Lipman M. Does immune reconstitution syndrome promote active tuberculosis in patients receiving highly active antiretroviral therapy?. AIDS 2005, 19:1201-1206.
15. Girardi E., Antonucci G., Vanacore P., et al. Impact of combination antiretroviral therapy on the risk of tuberculosis among persons with HIV infection. AIDS 2000, 14:1985-1991.
16. Lawn S.D., Little F., Bekker L.G., et al. Changing mortality risk associated with CD4 cell response to antiretroviral therapy in South Africa. AIDS 2009, 23:335-342.
17. Grubb J.R., Moorman A.C., Baker R.K., Masur H. HOPS investigators. The changing spectrum of pulmonary disease in patients with HIV infection on antiretroviral therapy. AIDS 2006, 20:1095-1107.
18. Ethiopia. Federal Ministry of Health. Implementation guideline for TB/HIV collaborative activities in Ethiopia. 2nd ed. Addis Ababa: MoH; 2007.
19. Lawn S.D., Landon M., David E., Linda G.B., Wood R. Short-term and long-term risk of tuberculosis associated with CD4 cell recovery during antiretroviral therapy in South Africa. AIDS 2009, 23:1717-1725.
20. Zhou J., Elliott J., Li P.C., et al. Risk and prognostic significance of tuberculosis in patients from The TREAT Asia HIV Observational Database. BMC Infect Dis 2009, 9:46.
21. Moh R., Danel C., Messou E., et al. Incidence and determinants of mortality and morbidity following early antiretroviral therapy initiation in HIV-infected adults in West Africa. AIDS 2007, 21:2483-2491.
22. Jerene D., Næss A., Lindtjørn B. Antiretroviral therapy at a district hospital in Ethiopia prevents death and tuberculosis in a cohort of HIV patients. Aids Res Ther 2006, 3:856-863.
23. Lawn S.D., Wood R. Incidence of tuberculosis during HAART in high-income and low-income countries. Clin Infect Dis 2005, 41:1783-1786.
24. Etard J.F., Ndiaye I., Mieg M.T., et al. Mortality and causes of death in adults receiving highly active antiretroviral therapy in Senegal: a 7-year cohort study. AIDS 2006, 20:1181-1189.
25. Kassa A., Teka A., Assefa Y., et al. Evaluation of collaborative TB/HIV activities in a general hospital in Addis Ababa, Ethiopia. BMC Research Notes 2012, 5:67.
26. Harries A.D., Hargreaves N.J., Kemp J., et al. Deaths from tuberculosis in sub-Saharan African countries with a high prevalence of HIV-1. Lancet 2001, 357:1519-1523.
27. Leung Yu J.K., Cheng Chen S.C., Wang K.Y., et al. True outcomes for patients on antiretroviral therapy who are "lost to follow-up" in Malawi. Bull World Health Organ 2007, 85:550-554.