The presence of a second rat has only subtle effects on the location-specific firing of hippocampal place cells

Hippocampus

Volumn 22, Issue 6, 2012, Pages 1405-1416

  Zynyuk, Larysa ^a   Huxter, John ^b   Muller, Robert U ^c   Fox, Steven E ^c  

^a UNIVERSITY OF BRISTOL   (United Kingdom)

^b PFIZER GLOBAL RESEARCH AND DEVELOPMENT   (United Kingdom)

^c SUNY Downstate Medical Center   (United States)

Author keywords

Animal to animal distance; Cognitive map; Hippocampal pyramidal cells; Social interaction; Spatial navigation

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN MAPPING; CONTROLLED STUDY; EXCITABILITY; HIPPOCAMPUS; HISTOLOGY; LOCOMOTION; MALE; NONHUMAN; PRIORITY JOURNAL; PYRAMIDAL NERVE CELL; RAT; RUNNING; SENSE OF COHERENCE; SOCIAL INTERACTION; SPATIAL DISCRIMINATION;

ACTION POTENTIALS; ANIMALS; ENVIRONMENT; HIPPOCAMPUS; MALE; RATS; RATS, LONG-EVANS; SPATIAL BEHAVIOR;

EID: 84861339342     PISSN: 10509631     EISSN: 10981063     Source Type: Journal    
DOI: 10.1002/hipo.20977     Document Type: Article

References (17)

1. Ho SA, Hori E, Kobayashi T, Umeno K, Tran AH, Ono T, Nishijo H. 2008. Hippocampal place cell activity during chasing of a moving object associated with reward in rats. Neuroscience 157: 254-270.
2. Markus, EJ, Qin, YL, Leonard, B, Skaggs, WE, McNaughton, BL, Barnes, CA. 1995. Interactions between location and task affect the spatial and directional firing of hippocampal neurons. J Neurosci, 15: 7079-7094.
3. Muller, RU. 1996. A quarter of a century of place cells. Neuron, 17: 813-822.
4. Muller RU, Kubie JL, Ranck JB. 1987. Spatial firing patterns of hippocampal complex-spike cells in a fixed environment. J Neurosci 7: 1935-1950.
5. Muller RU, Kubie JL, Bostock EM, Taube JS, Quirk GJ. 1991. Spatial firing correlates of neurons in the hippocampal formation of freely moving rats. In: Paillard J, editor. Brain and Space. Oxford: Oxford UP. pp 296-333.
6. O'Keefe J. 2007. Hippocampal neurophysiology in the behaving animal. In Andersen P et al, editors. The Hippocampus Book. Oxford: Oxford Univ. Press.
7. O'Keefe J, Conway DH. 1978. Hippocampal place units in the freely moving rat: Why they fire where they fire. Exp Brain Res 31: 573-590.
8. O'Keefe J, Speakman A. 1987. Single unit activity in the rat hippocampus during a spatial memory task. Exp Brain Res 68: 1-27.
9. Olypher AV, Lansky P, Muller RU, Fenton AA. 2003. Quantifying location-specific information in the discharge of rat hippocampal place cells. J Neurosci Methods 127: 123-135.
10. Parron C, Poucet B, Save E. 2006. Cooperation between the hippocampus and the entorhinal cortex in spatial memory: A disconnection study. Behav Brain Res 170: 99-109.
11. Rivard B, Li Y, Lenck-Santini PP, Poucet B, Muller RU. 2004. Representation of objects in space by two classes of hippocampal pyramidal cells. J Gen Physiol 124: 9-25.
12. Save E, Poucet B, Foreman N, Buhot MC. 1992. Object exploration and reactions to spatial and non-spatial changes in hooded rats following damage to parietal cortex or hippocampal formation. Behav Neurosci 10: 447-456.
13. Silverman JL, Yang M, Lord C, Crawley JN. 2010. Behavioural phenotyping assays for mouse models of autism. Nat Rev Neurosci 11: 490-502.
14. Solstad T, Boccara CN, Kropff E, Moser M, Moser EI. 2008. Representation of geometric borders in the entorhinal cortex. Science 322(5909): 1865-1868.
15. Telensky P, Svoboda J, Blahna K, Bures J, Kubik S, Stuchlik A. 2011. Functional inactivation of the rat hippocampus disrupts avoidance of a moving object. PNAS 108: 5414-5418.
16. Uekita T, Okanoya K. 2011. Hippocampus lesions induced deficits in social and spatial recognition in Octodon degus. Behav Brain Res 219: 302-309.
17. Young JW, Zhou X, Geyer MA. 2010. Animal models of schizophrenia. Cogn Affect Behav Neurosci 4: 391-433.