Acute and subacute toxicity and genotoxicity of schizonepetin, a naturally occurring monoterpene with antiviral activity

Food and Chemical Toxicology

Volumn 50, Issue 7, 2012, Pages 2256-2262

  Liu, Dongliang ^a   Geng, Ting ^a   Zhang, Li ^a   Yao, Weifeng ^a   Ding, Anwei ^a   Shan, Mingqiu ^a  

^a NANJING UNIVERSITY OF CHINESE MEDICINE   (China)

Author keywords

Genotoxicity; Safety; Schizonepetin; Toxicity

Indexed keywords

CHOLESTEROL; PLANT MEDICINAL PRODUCT; SCHIZONEPETIN; UNCLASSIFIED DRUG;

ACUTE TOXICITY; ADVERSE OUTCOME; AMES TEST; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIVIRAL ACTIVITY; ARTICLE; ASCITES; BODY WEIGHT; CHINESE HAMSTER; CHOLESTEROL BLOOD LEVEL; CHROMOSOME ABERRATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG EFFECT; DRUG SAFETY; DRUG STRUCTURE; FEMALE; GENOTOXICITY; HEMOGLOBIN DETERMINATION; INTESTINAL BLEEDING; LD 50; LUNG ALVEOLUS CELL; MALE; MEAN CORPUSCULAR VOLUME; MICRONUCLEUS TEST; MOTOR DYSFUNCTION; MOUSE; MUTAGENICITY; NONHUMAN; PERITONITIS; PTOSIS; RAT; REFLEX DISORDER; SALMONELLA TYPHIMURIUM; TOXICITY TESTING;

ANIMALS; ANTIVIRAL AGENTS; FEMALE; LETHAL DOSE 50; MALE; MICE; MICE, INBRED ICR; MONOTERPENES; MUTAGENICITY TESTS; NO-OBSERVED-ADVERSE-EFFECT LEVEL; SALMONELLA TYPHIMURIUM; TOXICITY TESTS, ACUTE; TOXICITY TESTS, SUBACUTE;

CRICETULUS GRISEUS; MAMMALIA; MUS; RATTUS; SALMONELLA TYPHIMURIUM;

EID: 84861332968     PISSN: 02786915     EISSN: 18736351     Source Type: Journal    
DOI: 10.1016/j.fct.2012.03.002     Document Type: Article

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