Endothelium-dependent and independent vasorelaxation induced by an n-butanolic fraction of bark of Scutia buxifolia Reiss (Rhamanaceae)

Journal of Ethnopharmacology

Volumn 141, Issue 3, 2012, Pages 997-1004

  Da Silva, Rita De C V De A F ^a   Crestani, Sandra ^a   De Souza, Priscila ^a   Boligon, Aline A ^b   Athayde, Margareth L ^b   Santos, Adair R S ^c   Marques, Maria Consuelo Andrade ^a   Kassuya, Cândida A L ^d   Da Silva Santos, José Eduardo ^c  

^a FEDERAL UNIVERSITY OF PARANÁ   (Brazil)

^b FEDERAL UNIVERSITY OF SANTA MARIA   (Brazil)

^c FEDERAL UNIVERSITY OF SANTA CATARINA   (Brazil)

^d UFGD   (Brazil)

Author keywords

Aorta; Endothelium; Hypertension; Nitric oxide pathway; Potassium channel

Indexed keywords

1H 1,2,4 OXADIAZOLO[4,3 A]QUINOXALIN 1 ONE; 4 AMINOPYRIDINE; BUTANOL; GLIBENCLAMIDE; IBERIOTOXIN; N(G) NITROARGININE METHYL ESTER; PHENYLEPHRINE; PLANT EXTRACT; SCUTIA BUXIFOLIA EXTRACT; TETRYLAMMONIUM; UNCLASSIFIED DRUG;

ANIMAL TISSUE; AORTA CONSTRICTION; ARTERY DILATATION; ARTERY ENDOTHELIUM; ARTICLE; BARK; BRAZIL; CONTROLLED STUDY; DRUG ANTAGONISM; DRUG MECHANISM; ETHNOPHARMACOLOGY; MALE; NONHUMAN; PLANT LEAF; RAT; RHAMNACEAE; SCUTIA BUXIFOLIA; TRADITIONAL MEDICINE; VASCULAR RING;

1-BUTANOL; ANIMALS; AORTA, THORACIC; CALCIUM; CYCLIC GMP; ENDOTHELIUM, VASCULAR; MALE; NITRIC OXIDE; PLANT BARK; PLANT EXTRACTS; PLANT LEAVES; POTASSIUM CHANNELS, CALCIUM-ACTIVATED; RATS; RATS, WISTAR; RHAMNACEAE; VASOCONSTRICTION; VASODILATOR AGENTS;

RATTUS; SCUTIA BUXIFOLIA;

EID: 84861330544     PISSN: 03788741     EISSN: 18727573     Source Type: Journal    
DOI: 10.1016/j.jep.2012.03.045     Document Type: Article

References (16)

1. A.A. Boligon, A.C. Feltrin, M.M. Machado, V. Janovik, and M.L. Athayde HPLC analysis and phytoconstituents isolated from ethyl acetate fraction of Scutia buxifolia reiss leaves Latin American Journal of Pharmacy 28 2009 121 124
2. A.A. Boligon, R.P. Pereira, A.C. Feltrin, M.M. Machado, V. Janovik, J.B.T. Rocha, and M.L. Athayde Antioxidant activities of flavonol derivatives from the leaves and stem bark of Scutia buxifolia Reiss Bioresource Technology 100 2009 6592 6598
3. A.A. Boligon, V. Janovik, A.C. Feltrin, M.M. Machado, J.K. Frohlich, and M.L. Athayde Phytoconstituents isolated from dichloromethane fraction of Scutia buxifolia Reissek stem bark Latin American Journal of Pharmacy 29 2010 450 453
4. A.A. Boligon, V. Janovik, J.K. Frohlich, T.B. Spader, A.L. Forbrig Froeder, S.H. Alves, and M.L. Athayde Antimicrobial and cytotoxic activities of leaves, twigs and stem bark of Scutia buxifolia Reissek Natural Product Research 2011 1 6
5. A.A. Boligon, V. Agertt, V. Janovik, R.C. Cruz, M.M.A. Campos, D. Guillaume, M.L. Athayde, and A.R.S. dos Santos Antimycobacterial activity of the fractions and compounds from Scutia buxifolia Revista Brasileira de Farmacognosia 22 2012 45 52
6. M. Feletou, and P.M. Vanhoutte Endothelium-dependent hyperpolarization of canine coronary smooth muscle British Journal of Pharmacology 93 1988 515 524
7. R.F. Furchgott, and J.V. Zawadzki The obligatory role of endothelial cells in the relaxation of arterial smooth muscle by acetylcholine Nature 288 1980 373 376
8. S.B. Guild, S. Jenkinson, and T.C. Muir Noradrenaline-stimulated inositol phosphate accumulation in arteries from spontaneously-hypertensive rats British Journal of Pharmacology 106 1992 859 864
9. G. Maldaner, P. Marangon, V. Ilha, M.S.B. Caro, R.A. Burrow, I.I. Dalcol, and A.F. Morel Cyclopeptide alkaloids from Scutia buxifolia Reiss Phytochemistry 72 2011 804 809
10. G. Mancia, G. De Backer, and A. Dominiczak Guidelines for the management of arterial hypertension: the task force for the management of arterial hypertension of the European Society of Hypertension and of the European Society of Cardiology Journal of Hypertension 25 2007 1105 1187
11. A.S. Menezes, M.A. Mostardeiro, N. Zanatta, and A.F. Morel Scutianine-J, a cyclopeptidic alkaloid isolated from Scutia buxifolia Phytochemistry 38 1995 783 786
12. S. Moncada, and E.A. Higgs The discovery of nitric oxide and its role in vascular biology British Journal of Pharmacology 147 2006 S193 S201
13. S. Moncada, and J.R. Vane Pharmacology and endogenous roles of prostaglandin endoperoxides, thromboxane A2, and prostacyclin Pharmacological Reviews 30 1978 293 331
14. A.F. Morel, G. Maldaner, V. Ilha, F. Missau, U.F. Silva, and I.I. Dalcol Cyclopeptide alkaloids from Scutia buxifolia Reiss and their antimicrobial activity Phytochemistry 66 2005 2571 2576
15. Y.D. Rattmann, M.R. Terluk, W.M. Souza, C.A. Santos, M.W. Biavatti, L.B. Torres, S. Mesia-Vela, L. Rieck, J.E. da Silva-Santos, and M.C. Marques Effects of alkaloids of Himatanthus lancifolius (Muell. Arg.) Woodson, Apocynaceae, on smooth muscle responsiveness Journal of Ethnopharmacology 100 2005 268 275
16. R. Wasicky, M. Wasicky, and R. Joachimovits Erstuntersuchungen na Coronilha-Scutia buxifolia Reissek Planta Medica 12 1964 13 25