Accuracy and reliability of microbubble ultrasound measurements for the non-invasive assessment of hepatic fibrosis in chronic hepatitis C

Hepatology Research

Volumn 42, Issue 5, 2012, Pages 515-522

  Cobbold, Jeremy F L ^a   Patel, Dhupal ^a   Fitzpatrick, Julie A ^a   Patel, Nayna ^c   Crossey, Mary M E ^a   AbdAlla, Mohamed Saad ^a,e   Goldin, Robert D ^b   Vennart, William ^d   Thomas, Howard C ^a   Taylor Robinson, Simon D ^a  

^a Section of Hepatology and Gastroenterology   (United Kingdom)

^b IMPERIAL COLLEGE LONDON   (United Kingdom)

^c IMPERIAL COLLEGE HEALTHCARE NHS TRUST   (United Kingdom)

^d PFIZER GLOBAL RESEARCH AND DEVELOPMENT   (United Kingdom)

^e National Liver Institute   (Egypt)

Author keywords

Fibrosis; Hepatic vein transit time; Hepatitis C; Microbubble contrast; Non invasive; Ultrasound

Indexed keywords

ADULT; AGED; ARTICLE; DIAGNOSTIC ACCURACY; DIAGNOSTIC VALUE; DISEASE SEVERITY; ECHOGRAPHY; FEMALE; GASTROINTESTINAL TRANSIT; HEPATIC TRANSIT TIME; HEPATIC VEIN TRANSIT TIME; HEPATITIS C; HUMAN; INTERMETHOD COMPARISON; LIVER CIRRHOSIS; LIVER FIBROSIS; MAJOR CLINICAL STUDY; MALE; MICROBUBBLE; PREDICTIVE VALUE; PRIORITY JOURNAL;

EID: 84861324301     PISSN: 13866346     EISSN: 1872034X     Source Type: Journal    
DOI: 10.1111/j.1872-034X.2011.00948.x     Document Type: Article

References (18)

1. Regev A, Berho M, Jeffers LJ et al. Sampling error and intraobserver variation in liver biopsy in patients with chronic hepatitis C virus infection. Am J Gastroenterol 2002;97: 2614-8.
2. Lim AKP, Taylor-Robinson SD, Patel N et al. Hepatic vein transit times using a microbubble agent can predict disease severity non-invasively in patients with hepatitis C. Gut 2005; 54: 128-33.
3. Castera L, Giada S, Le Bail B et al. Prospective comparison of two algorithms combining non-invasive methods for staging liver fibrosis in chronic hepatitis C. J Hepatol 2010;52: 191-8.
4. Friedrich-Rust M, Ong MF, Martens S et al. Performance of transient elastography for the staging of liver fibrosis: a meta-analysis. Gastroenterology 2008; 134: 960-74.
5. Shaheen AA, Myers RP. Diagnostic accuracy of the aspartate aminotransferase-to-platelet ratio index for the prediction of hepatitis C related fibrosis: a systematic review. Hepatology 2007; 46: 912-21.
6. Albrecht T, Blomley MJK, Cosgrove DO et al. Non-invasive diagnosis of hepatic cirrhosis by transit-time analysis of an ultrasound contrast agent. Lancet 1999; 353: 1579-83.
7. Blomley MJK, Lim AKP, Harvey CJ et al. Liver microbubble transit time compared with histology and Child-Pugh score in diffuse liver disease: a cross sectional study. Gut 2003; 52: 1188-93.
8. Hirota M, Kaneko T, Sugimoto H. Intrahepatic circulatory time analysis of an ultrasound contrast agent in liver cirrhosis. Liver Int 2005; 25: 337-42.
9. Abbattista T, Ridolfi F, Ciabattoni E et al. Diagnosis of liver cirrhosis by transit-time analysis at contrast enhanced ultrasound. Radiol Med 2008; 113: 860-74.
10. Cobbold JFL, Crossey MME, Colman P et al. Optimal combinations of ultrasound-based and serum markers of disease severity in patients with chronic hepatitis C. J Viral Hepat 2010; 17: 537-45.
11. Lim AKP, Patel N, Eckersley RJ et al. Hepatic vein transit time of SonoVue: a comparative study with Levovist. Radiology 2006; 240 (1): 130-5.
12. Ridolfi F, Abbattista T, Marini F et al. Contrast-enhanced ultrasound to evaluate the severity of chronic hepatitis C. Dig Liver Dis 2007; 39: 929-35.
13. Sugimoto H, Kaneko T, Hirota M, Tezel E, Nakao A. Earlier hepatic vein transit-time measured by contrast ultrasonography reflects intrahepatic haemodynamic changes accompanying cirrhosis. J Hepatol 2002; 37: 578-83.
14. Ishak K, Baptista A, Bianchi L et al. Histological grading and staging of chronic hepatitis. J Hepatol 1995; 22:696-9.
15. Fraquelli M, Rigamonti C, Casazza G et al. Reproducibility of transient elastography in the evaluation of liver fibrosis in patients with chronic liver disease. Gut 2007; 56:968-73.
16. Hanley JA, McNeil BJ. A method of comparing the areas under receiver operating characteristic curves derived from the same cases. Radiology 1983; 148: 839-43.
17. Ishibashi H, Maruyama H, Takahashi M, Fujiwara K, Imazeki F, Yokosuka O. Assessment of hepatic fibrosis by analysis of the dynamic behaviour of microbubbles during contrast ultrasound. Liver Int 2010; 30: 1355-63.
18. Staub F, Tournoux-Facon C, Roumy J et al. Liver fibrosis staging with contrast-enhanced ultrasonography: prospective multicentre study compared with METAVIR scoring. Eur Radiol 2009; 19: 1991-7.