Differences in body fat distribution assessed by ultrasonography in patients receiving antiretroviral drugs

Revista da Associacao Medica Brasileira

Volumn 58, Issue 2, 2012, Pages 197-203

  Signorini, Dario Jose Hart Pontes ^a   de Oliveira Netto, Ana Maria Schmidt ^b   Monteiro, Michelle Carreira Miranda ^c   Signorini, Dario Hart ^d   Codeço, Cláudia Torres ^e   Bastos, Francisco I ^f   Gabbay, Sergio ^g   de Fátima Castro de Andrade, Marion ^h  

^a FEDERAL UNIVERSITY OF THE STATE OF RIO DE JANEIRO   (Brazil)

^b PONTIFICAL CATHOLIC UNIVERSITY OF RIO DE JANEIRO   (Brazil)

^c HOSPITAL UNIVERSITÁRIO GAFFRÉE E GUINLE   (Brazil)

^d ESTÁCIO DE SÁ UNIVERSITY   (Brazil)

^e INSTITUTO OSWALDO CRUZ   (Brazil)

^f Oswaldo Cruz Foundation   (Brazil)

^g STATE UNIVERSITY OF RIO DE JANEIRO   (Brazil)

^h FEDERAL UNIVERSITY OF RIO DE JANEIRO   (Brazil)

Author keywords

Cross sectional studies; Highly active anti retroviral therapy; HIV infection; HIV related lipodystrophy syndrome

Indexed keywords

ANTIRETROVIRUS AGENT;

ADULT; ARTICLE; BODY FAT DISTRIBUTION; ECHOGRAPHY; FEMALE; HIGHLY ACTIVE ANTIRETROVIRAL THERAPY; HIV ASSOCIATED LIPODYSTROPHY; HUMAN; MALE; SEX DIFFERENCE; SKINFOLD THICKNESS; STATISTICAL MODEL;

ADULT; ANTI-RETROVIRAL AGENTS; ANTIRETROVIRAL THERAPY, HIGHLY ACTIVE; BODY FAT DISTRIBUTION; FEMALE; HIV-ASSOCIATED LIPODYSTROPHY SYNDROME; HUMANS; LINEAR MODELS; MALE; SEX FACTORS; SKINFOLD THICKNESS;

EID: 84861311361     PISSN: 01044230     EISSN: None     Source Type: Journal    
DOI: 10.1590/S0104-42302012000200015     Document Type: Article

References (32)

1. Signorini DJHP, Codeço CT, Carvalho MS, Campos DP, Monteiro MCM, Andrade MFC, et al. Effect of sociodemographic, clinical-prophylactic and therapeutic procedures on survival of AIDS patients assisted in a Brazilian outpatient clinic. Rev Bras Epidemiol. 2005;8(3)253-61.
2. Marconi VC, Grandits GA, Weintrob AC, Chun H, Landrum ML, Ganesan A, et al. Outcomes of highly active antiretroviral therapy in the context of universal access to healthcare: the U.S. Military HIV Natural History Study. AIDS Res Ther. 2010;7(1):14.
3. Diehl LA, Dias JR, Paes AC, Thomazini MC, Garcia LR, Cinagawa E, et al. Prevalence of HIV-associated lipodystrophy in Brazilian outpatients: relation with metabolic syndrome and cardiovascular risk factors. Arq Bras Endocrinol Metab. 2008;52(4):658-67.
4. Signorini DJ, Monteiro MC, Signorini DH, Eyer-Silva WA. Prevalence and determinant factors to lipid abnormalities among HIV-infected patients: a cross-sectional study of 812 patients. Arq Bras Endocrinol Metabol. 2010;54(6):583.
5. Santos CP, Felipe YX, Braga PE, Ramos D, Lima RO, Segurado AC. Self-perception of body changes in persons living with HIV/AIDS: prevalence and associated factors. AIDS. 2005;19(Suppl 4):S14-21.
6. Lichtenstein KA, Ward DJ, Moorman AC, Delaney KM, Young B, Palella FJ Jr, et al. Clinical assessment of HIV-associated lipodystrophy in an ambulatory population. AIDS. 2001;15(11):1389-98.
7. Gelenske T, Bandeira EFFA, Alencar Ximenes RA, Lacerda de Melo HR, Militao de Albuquerque MD, Carvalho EH, et al. Risk factors in human immunodeficiency virus/acquired immunodeficiency syndrome patients undergoing antiretroviral therapy in the state of Pernambuco, Brazil: a case-control study. Metab Syndr Relat Disord. 2010;8(3):271-7.
8. Safrin S, Grunfeld C. Fat distribution and metabolic changes in patients with HIV infection. AIDS.1999;13(18):2493-505.
9. Huang JS, Becerra K, Fernandez S, Lee D, Mathews WC. The impact of HIV-associated lipodystrophy on healthcare utilization and costs. AIDS Res Ther. 2008;5:14.
10. Associação Médica Brasileira, aSdE, Conselho Federal de Medicina, Federação Nacional dos Médicos. Classificação Brasileira Hierarquizada de Procedimentos Médicos (CBHPM). São Paulo; 2010. [cited 2011]. Available from: http://www.amb.org.br/teste/cbhpm/cbhpm_2010.pdf.
11. Martinez E, Bianchi L, Garcia-Viejo MA, Bru C, Gatell JM. Sonographic assessment of regional fat in HIV-1-infected people. Lancet. 2000;356(9239):1412-3.
12. Brasil. Recomendações para terapia antirretroviral em adultos infectados pelo HIV, 2008. [cited 2011 feb 2]. Available from: http://www.aids.gov.br/sites/default/files/consensoAdulto005c_2008montado.pdf.
13. Jones JL, Hanson DL, Dworkin MS, Alderton DL, Fleming PL, Kaplan MD, et al. Division of HIV/AIDS Prevention Surveillance and Epidemiology. Surveillance for AIDS-defining opportunistic illnesses, 1992-1997. Available from: http://www.cdc.gov/mmwr/preview/mmwrhtml/00056917.htm.
14. Radominski RB, Vezozzo DP, Cerri GG, Halpern A. O uso da ultrassonografia na avaliação da distribuição de gordura abdominal. Arq Bras Endocrinol Metab. 2000;44(1):5-12.
15. Dalgaard P. Introductory statistics with R. New York: Springer; 2002.
16. Team RDC. R: a language and environment for statistical computing. 2.11. Vienna: R Foundation for Statistical Computing; 2011.
17. UNAIDS/WHO. Joint United Nations Programme on HIV/AIDS WHO. UNAIDS report on the global AIDS epidemic 2010. 2010.
18. Boletim Epidemiológico Aids. DST (Versão Preliminar). Brasília (DF); 2010. [cited 2011 feb 2]. Available from: http://www.aids.gov.br/sites/default/files/publicacao/2010/boletim2010_preliminar_pdf_34434.pdf.
19. Ministério da Saúde. DST. AIDS hepatites virais. Brasília (DF): Ministério da Saúde; 2011. [cited 2011 feb 4]. Available from: http://www.aids.gov.br/pagina/quais-sao-os-antirretrovirais.
20. Villarroya F, Domingo P, Giralt M. Drug-induced lipotoxicity: lipodystrophy associated with HIV-1 infection and antiretroviral treatment. Biochim Biophys Acta. 2010;1801(3):392-9.
21. Monnerat BZ, Cerutti Junior C, Canicali SC, Motta TR. Clinical and biochemical evaluation of HIV-related lipodystrophy in an ambulatory population from the Hospital Universitario Cassiano Antonio de Morais, Vitoria, ES, Brazil. Braz J Infect Dis. 2008;12(4):364-8.
22. Kotler DP, Thea DM, Heo M, Allison DB, Engelson ES, Wang J, et al. Relative influences of sex, race, environment, and HIV infection on body composition in adults. Am J Clin Nutr. 1999;69(3):432-9.
23. Tien PC, Benson C, Zolopa AR, Sidney S, Osmond D, Grunfeld C. The study of fat redistribution and metabolic change in HIV infection (FRAM): methods, design, and sample characteristics. Am J Epidemiol. 2006;163(9):860-9.
24. Carr A, Emery S, Law M, Puls R, Lundgren JD, Powderly WG. An objective case definition of lipodystrophy in HIV-infected adults: a case-control study. Lancet. 2003;361(9359):726-35.
25. Martinez E, Milinkovic A, Bianchi L, Gatell JM. Considerations about the value of sonography for the measurement of regional body fat. AIDS. 2006;20(3):465-6.
26. Padilla S, Gallego JA, Masia M, Ardoy F, Hernandez I, Gutierrez F. Ultrasonography and anthropometry for measuring regional body fat in HIV-infected patients. Current HIV Res. 2007;5(5):459-66.
27. Guimarães MM, Oliveira AR Jr, Penido MG, Queiroz LC, Goulart EM, Greco DB, et al. Ultrasonographic measurement of intra-abdominal fat thickness in HIV-infected patients treated or not with antiretroviral drugs and its correlation to lipid and glycemic profiles. Ann Nutr Metab. 2007;51(1):35-41.
28. Asensi V, Martin-Roces E, Carton J, Collazos J, Maradona J, Alonso A, et al. Perirenal fat diameter measured by echography could be an early predictor of lipodystrophy in HIV type 1-infected patients receiving highly active antiretroviral therapy. Clin Infect Dis. 2004;39(2):240-7.
29. Gulizia R, Vercelli A, Gervasoni C, Ortu M, Calliada F, Troia G, et al. Controversy concerning role of ultrasonographic lipoatrophy assessments in HIV patients. AIDS. 2006;20(5):789-90.
30. Carey D, Wand H, Martin A, Rothwell S, Emery S, Cooper DA, et al. Evaluation of ultrasound for assessing facial lipoatrophy in a randomized, placebo-controlled trial. AIDS. 2005;19(12):1325-7.
31. Asensi V, Martin-Roces E, Collazos J, Carton JA, Maradona JA, Alonso A, et al. Association between physical and echographic fat thickness assessments and a lipodystrophy grading scale in lipodystrophic HIV patients: practical implications. AIDS Res Hum Retroviruses. 2006;22(9):830-6.
32. Nunn AS, da Fonseca EM, Bastos FI, Gruskin S. AIDS treatment in Brazil: impacts and challenges. Health Aff (Millwood). 2009;28(4):1103-13.