메뉴 건너뛰기




Volumn 12, Issue 5, 2012, Pages 547-549

The roadmap of TRAIL apoptotic pathway-targeted cancer therapies: What is next?

Author keywords

apoptosis; cancer; death receptor; monoclonal antibody; target agents; TRAIL

Indexed keywords

BEVACIZUMAB; CARBOPLATIN; DROZITUMAB; DULANERMIN; LEXATUMUMAB; MAPATUMUMAB; PACLITAXEL; RECOMBINANT TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND; TIGATUZUMAB; TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND;

EID: 84861303356     PISSN: 14737140     EISSN: 17448328     Source Type: Journal    
DOI: 10.1586/era.12.33     Document Type: Review
Times cited : (1)

References (20)
  • 1
    • 0032575714 scopus 로고    scopus 로고
    • Death receptors: Signaling and modulation
    • Ashkenazi A, Dixit VM. Death receptors: signaling and modulation. Science 281(5381), 1305-1308 (1998).
    • (1998) Science , vol.281 , Issue.5381 , pp. 1305-1308
    • Ashkenazi, A.1    Dixit, V.M.2
  • 2
    • 0033169230 scopus 로고    scopus 로고
    • 2 8 A resolution crystal structure of human TRAIL, a cytokine with selective antitumor activity
    • Cha SS, Kim MS, Choi YH et al. 2.8 A resolution crystal structure of human TRAIL, a cytokine with selective antitumor activity. Immunity 11(2), 253-261 (1999).
    • (1999) Immunity , vol.11 , Issue.2 , pp. 253-261
    • Cha, S.S.1    Kim, M.S.2    Choi, Y.H.3
  • 3
    • 0032713075 scopus 로고    scopus 로고
    • Safety and antitumor activity of recombinant soluble Apo2 ligand
    • Ashkenazi A, Pai RC, Fong S et al. Safety and antitumor activity of recombinant soluble Apo2 ligand. J. Clin. Invest. 104(2), 155-162 (1999).
    • (1999) J. Clin. Invest. , vol.104 , Issue.2 , pp. 155-162
    • Ashkenazi, A.1    Pai, R.C.2    Fong, S.3
  • 4
    • 0032929520 scopus 로고    scopus 로고
    • Tumoricidal activity of tumor necrosis factor-related apoptosis-inducing ligand in vivo
    • Walczak H, Miller RE, Ariail K et al. Tumoricidal activity of tumor necrosis factor-related apoptosis-inducing ligand in vivo. Nat. Med. 5(2), 157-163 (1999).
    • (1999) Nat. Med. , vol.5 , Issue.2 , pp. 157-163
    • Walczak, H.1    Miller, R.E.2    Ariail, K.3
  • 5
    • 0034022160 scopus 로고    scopus 로고
    • Apoptosis induced in normal human hepatocytes by tumor necrosis factor-related apoptosis-inducing ligand
    • Jo M, Kim TH, Seol DW et al. Apoptosis induced in normal human hepatocytes by tumor necrosis factor-related apoptosis-inducing ligand. Nat. Med. 6(5), 564-567 (2000).
    • (2000) Nat. Med. , vol.6 , Issue.5 , pp. 564-567
    • Jo, M.1    Kim, T.H.2    Seol, D.W.3
  • 6
    • 0034026719 scopus 로고    scopus 로고
    • Steering anti-cancer drugs away from the TRAIL
    • Nagata S. Steering anti-cancer drugs away from the TRAIL. Nat. Med. 6(5), 502-503 (2000).
    • (2000) Nat. Med. , vol.6 , Issue.5 , pp. 502-503
    • Nagata, S.1
  • 7
    • 0035050960 scopus 로고    scopus 로고
    • Differential hepatocyte toxicity of recombinant Apo2L/TRAIL versions
    • Lawrence D, Shahrokh Z, Marsters S et al. Differential hepatocyte toxicity of recombinant Apo2L/TRAIL versions. Nat. Med. 7(4), 383-385 (2001).
    • (2001) Nat. Med. , vol.7 , Issue.4 , pp. 383-385
    • Lawrence, D.1    Shahrokh, Z.2    Marsters, S.3
  • 8
    • 9244237679 scopus 로고    scopus 로고
    • TRAIL inhibits tumor growth but is nontoxic to human hepatocytes in chimeric mice
    • Hao C, Song JH, Hsi B et al. TRAIL inhibits tumor growth but is nontoxic to human hepatocytes in chimeric mice. Cancer Res. 64(23), 8502-8506 (2004).
    • (2004) Cancer Res. , vol.64 , Issue.23 , pp. 8502-8506
    • Hao, C.1    Song, J.H.2    Hsi, B.3
  • 10
    • 77956414973 scopus 로고    scopus 로고
    • Phase I dose-escalation study of recombinant human Apo2L/TRAIL, a dual proapoptotic receptor agonist, in patients with advanced cancer
    • Herbst RS, Eckhardt SG, Kurzrock R et al. Phase I dose-escalation study of recombinant human Apo2L/TRAIL, a dual proapoptotic receptor agonist, in patients with advanced cancer. J. Clin. Oncol. 28(17), 2839-2846 (2010).
    • (2010) J. Clin. Oncol. , vol.28 , Issue.17 , pp. 2839-2846
    • Herbst, R.S.1    Eckhardt, S.G.2    Kurzrock, R.3
  • 11
    • 77951894266 scopus 로고    scopus 로고
    • Phase 1b study of dulanermin (recombinant human Apo2L/TRAIL) in combination with paclitaxel, carboplatin, and bevacizumab in patients with advanced non-squamous non-small-cell lung cancer
    • Soria JC, Smit E, Khayat D et al. Phase 1b study of dulanermin (recombinant human Apo2L/TRAIL) in combination with paclitaxel, carboplatin, and bevacizumab in patients with advanced non-squamous non-small-cell lung cancer. J. Clin. Oncol. 28(9), 1527-1533 (2010).
    • (2010) J. Clin. Oncol. , vol.28 , Issue.9 , pp. 1527-1533
    • Soria, J.C.1    Smit, E.2    Khayat, D.3
  • 12
    • 81755161607 scopus 로고    scopus 로고
    • Randomized Phase II study of dulanermin in combination with paclitaxel, carboplatin, and bevacizumab in advanced non-small-cell lung cancer
    • Soria JC, Mark Z, Zatloukal P et al. Randomized Phase II study of dulanermin in combination with paclitaxel, carboplatin, and bevacizumab in advanced non-small-cell lung cancer. J. Clin. Oncol. 29(33), 4442-4451 (2011).
    • (2011) J. Clin. Oncol. , vol.29 , Issue.33 , pp. 4442-4451
    • Soria, J.C.1    Mark, Z.2    Zatloukal, P.3
  • 13
    • 17944376030 scopus 로고    scopus 로고
    • Tumoricidal activity of a novel anti-human DR5 monoclonal antibody without hepatocyte cytotoxicity
    • Ichikawa K, Liu W, Zhao L et al. Tumoricidal activity of a novel anti-human DR5 monoclonal antibody without hepatocyte cytotoxicity. Nat. Med. 7(8), 954-960 (2001).
    • (2001) Nat. Med. , vol.7 , Issue.8 , pp. 954-960
    • Ichikawa, K.1    Liu, W.2    Zhao, L.3
  • 14
    • 34248187996 scopus 로고    scopus 로고
    • Phase I pharmacokinetic and biologic correlative study of mapatumumab, a fully human monoclonal antibody with agonist activity to tumor necrosis factor-related apoptosis-inducing ligand receptor-1
    • Tolcher AW, Mita M, Meropol NJ et al. Phase I pharmacokinetic and biologic correlative study of mapatumumab, a fully human monoclonal antibody with agonist activity to tumor necrosis factor-related apoptosis-inducing ligand receptor-1. J. Clin. Oncol. 25(11), 1390-1395 (2007).
    • (2007) J. Clin. Oncol. , vol.25 , Issue.11 , pp. 1390-1395
    • Tolcher, A.W.1    Mita, M.2    Meropol, N.J.3
  • 15
    • 35948952826 scopus 로고    scopus 로고
    • Phase 1 and pharmacokinetic study of lexatumumab in patients with advanced cancers
    • Plummer R, Attard G, Pacey S et al. Phase 1 and pharmacokinetic study of lexatumumab in patients with advanced cancers. Clin. Cancer Res. 13(20), 6187-6194 (2007).
    • (2007) Clin. Cancer Res. , vol.13 , Issue.20 , pp. 6187-6194
    • Plummer, R.1    Attard, G.2    Pacey, S.3
  • 16
    • 76749110412 scopus 로고    scopus 로고
    • A Phase I safety and pharmacokinetic study of the death receptor 5 agonistic antibody PRO95780 in patients with advanced malignancies
    • Camidge DR, Herbst RS, Gordon MS et al. A Phase I safety and pharmacokinetic study of the death receptor 5 agonistic antibody PRO95780 in patients with advanced malignancies. Clin. Cancer Res. 16(4), 1256-1263 (2010).
    • (2010) Clin. Cancer Res. , vol.16 , Issue.4 , pp. 1256-1263
    • Camidge, D.R.1    Herbst, R.S.2    Gordon, M.S.3
  • 17
    • 76349085626 scopus 로고    scopus 로고
    • Phase II trial of mapatumumab, a fully human agonistic monoclonal antibody that targets and activates the tumour necrosis factor apoptosis-inducing ligand receptor-1 (TRAIL-R1), in patients with refractory colorectal cancer
    • Trarbach T, Moehler M, Heinemann V et al. Phase II trial of mapatumumab, a fully human agonistic monoclonal antibody that targets and activates the tumour necrosis factor apoptosis-inducing ligand receptor-1 (TRAIL-R1), in patients with refractory colorectal cancer. Br. J. Cancer 102(3), 506-512 (2010).
    • (2010) Br. J. Cancer , vol.102 , Issue.3 , pp. 506-512
    • Trarbach, T.1    Moehler, M.2    Heinemann, V.3
  • 18
    • 62449168519 scopus 로고    scopus 로고
    • TRAIL agonists on clinical trials for cancer therapy: The promises and the challenges
    • Bellail AC, Qi L, Mulligan P, Chhabra V, Hao C. TRAIL agonists on clinical trials for cancer therapy: the promises and the challenges. Rev. Recent Clin. Trials 4(1), 34-41 (2009).
    • (2009) Rev. Recent Clin. Trials , vol.4 , Issue.1 , pp. 34-41
    • Bellail, A.C.1    Qi, L.2    Mulligan, P.3    Chhabra, V.4    Hao, C.5
  • 19
    • 0034989624 scopus 로고    scopus 로고
    • In vitro susceptibility to TRAIL-induced apoptosis of acute leukemia cells in the context of TRAIL receptor gene expression and constitutive NF-kappa B activity
    • Wuchter C, Krappmann D, Cai Z et al. In vitro susceptibility to TRAIL-induced apoptosis of acute leukemia cells in the context of TRAIL receptor gene expression and constitutive NF-kappa B activity. Leukemia 15(6), 921-928 (2001).
    • (2001) Leukemia , vol.15 , Issue.6 , pp. 921-928
    • Wuchter, C.1    Krappmann, D.2    Cai, Z.3
  • 20
    • 84861325324 scopus 로고    scopus 로고
    • A20 ubiquitin ligase-mediated polyubiquitination of RIP1 inhibits caspase-8 cleavage and TRAIL-induced apoptosis in glioblastoma
    • Bellail AC, Olson JJ, Yang X, Chen ZJ, Hao C. A20 ubiquitin ligase-mediated polyubiquitination of RIP1 inhibits caspase-8 cleavage and TRAIL-induced apoptosis in glioblastoma. Cancer Discov. 2(2), 140-155 (2012).
    • (2012) Cancer Discov. , vol.2 , Issue.2 , pp. 140-155
    • Bellail, A.C.1    Olson, J.J.2    Yang, X.3    Chen, Z.J.4    Hao, C.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.