Lymphocyte composition and distribution in inflammatory, well-differentiated retroperitoneal liposarcoma: Clues to a potential adaptive immune response and therapeutic implications

American Journal of Surgical Pathology

Volumn 36, Issue 6, 2012, Pages 941-944

  Tseng, William W ^a   Demicco, Elizabeth G ^a   Lazar, Alexander J ^a   Lev, Dina C ^a   Pollock, Raphael E ^a  

^a UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

TUMOR ANTIGEN;

ADAPTIVE IMMUNITY; ADULT; AGED; FEMALE; HUMAN; IMMUNOLOGY; IMMUNOTHERAPY; INFLAMMATION; LETTER; LIPOSARCOMA; MALE; MIDDLE AGED; PATHOLOGY; RETROPERITONEAL TUMOR; RETROSPECTIVE STUDY; TUMOR ASSOCIATED LEUKOCYTE;

ADAPTIVE IMMUNITY; ADULT; AGED; ANTIGENS, NEOPLASM; FEMALE; HUMANS; IMMUNOTHERAPY; INFLAMMATION; LIPOSARCOMA; LYMPHOCYTES, TUMOR-INFILTRATING; MALE; MIDDLE AGED; RETROPERITONEAL NEOPLASMS; RETROSPECTIVE STUDIES;

EID: 84861232006     PISSN: 01475185     EISSN: 15320979     Source Type: Journal    
DOI: 10.1097/PAS.0b013e31824f2594     Document Type: Letter

References (20)

1. Argani P, Facchetti F, Inghirami G, et al. Lymphocyte-rich well-differentiated liposarcoma: report of nine cases. Am J Surg Pathol. 1997;21:884-895. (Pubitemid 27402807)
2. Calabrò L, Danielli R, Sigalotti L, et al. Clinical studies with anti-CTLA-4 antibodies in non-melanoma indications. Semin Oncol. 2010;37:460-467.
3. Dieu-Nosjean MC, Antoine M, Danel C, et al. Long-term survival for patients with non-small-cell lung cancer with intratumoral lymphoid structures. J Clin Oncol. 2008;26:4410-4417.
4. Dodd LG. Update on liposarcoma: a review for cytopathologists. Diagn Cytopathol. 2011. [Epub ahead of print].
5. Gajewski TF. Cancer immunotherapy. Mol Oncol. 2012. [Epub ahead of print].
6. Gooden MJ, de Bock GH, Leffers N, et al. The prognostic influence of tumourinfiltrating lymphocytes in cancer: a systematic review with meta-analysis. Br J Cancer. 2011;105:93-103.
7. Hodi FS, O'Day SJ, McDermott DF, et al. Improved survival with ipilimumab in patients with metastatic melanoma. N Engl J Med. 2010;363:711-723.
8. Kawano R, Nishie A, Yoshimitsu K, et al. Retroperitoneal well-differentiated inflammatory liposarcoma: a diagnostic dilemma. Radiat Med. 2008;26:450-453.
9. Kirk CJ, Hartigan-O'Connor D, Mulé JJ. The dynamics of the T-cell antitumor response: chemokine-secreting dendritic cells can prime tumor-reactive T cells extranodally. Cancer Res. 2001;61:8794-8802. (Pubitemid 34013893)
10. Kraus MD, Guillou L, Fletcher CD. Well-differentiated inflammatory liposarcoma: an uncommon and easily overlooked variant of a common sarcoma. Am J Surg Pathol. 1997;21:518-527. (Pubitemid 27213065)
11. Lahat G, Anaya DA, Wang X, et al. Resectable well-differentiated versus dedifferentiated liposarcomas: two different diseases possibly requiring different treatment approaches. Ann Surg Oncol. 2008;15: 1585-1593.
12. 4+ T reg cells. J Exp Med. 2006;203: 1701-1711. (Pubitemid 44036276)
13. Nathan H, Raut CP, Thornton K, et al. Predictors of survival after resection of retroperitoneal sarcoma: a populationbased analysis and critical appraisal of the AJCC staging system. Ann Surg. 2009;250: 970-976.
14. Rosenberg SA. Cell transfer immunotherapy for metastatic solid cancer-what clinicians need to know. Nat Rev Clin Oncol. 2011;8:577-585.
15. Singer S, Antonescu CR, Riedel E, et al. Histologic subtype and margin of resection predict pattern of recurrence and survival for retroperitoneal liposarcoma. Ann Surg. 2003;238:358-370.
16. Talmadge JE. Immune cell infiltration of primary and metastatic lesions: mechanisms and clinical impact. Semin Cancer Biol. 2011;21:131-138.
17. Tarhini A, Lo E, Minor DR. Releasing the brake on the immune system: ipilimumab in melanoma and other tumors. Cancer Biother Radiopharm. 2010;25: 601-613.
18. Ueno H, Klechevsky E, Morita R, et al. Dendritic cell subsets in health and disease. Immunol Rev. 2007;219:118-142. (Pubitemid 47393528)
19. Willems SM, Szuhai K, Hartgrink H, et al. CT-guided, COBRA-FISHassisted diagnosis of well-differentiated liposarcoma (inflammatory subtype) of the retroperitoneum. Histopathology. 2007;51:422-426. (Pubitemid 47301620)
20. Wu HH, Harshbarger KE, McCandless DG. Fine-needle aspiration cytology of well-differentiated inflammatory liposarcoma: a case report with histologic follow-up. Diagn Cytopathol. 1999;20:229-232. (Pubitemid 29162829)