Development and validation of an HPLC/UV assay for separation and quantification of peptide antigens from a liposomal vaccine delivery platform

Journal of Pharmaceutical and Biomedical Analysis

Volumn 66, Issue , 2012, Pages 176-182

  Penwell, Andrea ^a   Sharp, Kendall ^a   Mansour, Marc ^a   Sammatur, Leeladhar ^a  

^a Immunovaccine Inc   (Canada)

Author keywords

DepoVax ; Liposome formulation; Peptide; Reversed phase HPLC; Validation

Indexed keywords

ANTIGEN; BICARBONATE; BUTANOL; CANCER VACCINE; DEPOVAX; DPX 0907; LIPID; LIPOSOME; PEPTIDE; PEPTIDE ANTIGEN; PLACEBO; UNCLASSIFIED DRUG; WATER;

ACCURACY; ANALYTIC METHOD; ARTICLE; BREAST CANCER; CANCER PATIENT; CHEMICAL COMPOSITION; CONCENTRATION (PARAMETERS); DRUG ANALYSIS; DRUG FORMULATION; DRUG ISOLATION; DRUG RELEASE; DRUG SOLUBILITY; DRUG STABILITY; HUMAN; HYDROPHILICITY; HYDROPHOBICITY; LIMIT OF QUANTITATION; LIPOSOMAL DELIVERY; LIQUID LIQUID EXTRACTION; OVARY CANCER; PATENT; PHASE 1 CLINICAL TRIAL; PRIORITY JOURNAL; PROSTATE CANCER; REPRODUCIBILITY; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; ULTRAVIOLET SPECTROSCOPY; VALIDATION PROCESS;

ANTIGENS; CANCER VACCINES; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; LIPOSOMES; PEPTIDES; REPRODUCIBILITY OF RESULTS;

EID: 84861225907     PISSN: 07317085     EISSN: 1873264X     Source Type: Journal    
DOI: 10.1016/j.jpba.2012.03.046     Document Type: Article

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