A high pH based reversed-phase high performance liquid chromatographic method for the analysis of aminoglycoside plazomicin and its impurities

Journal of Pharmaceutical and Biomedical Analysis

Volumn 66, Issue , 2012, Pages 75-84

  Tan, Li ^a   Wlasichuk, Kenneth B ^a   Schmidt, Donald E ^a   Campbell, Robert L ^a   Hirtzer, Pam ^b   Cheng, Lisa ^c   Karr, Dane E ^a  

^a Achaogen Inc   (United States)

^b PharmDev Associates LLC   (United States)

^c Biopharm Consulting Services   (United States)

Author keywords

Aminoglycoside; High pH based mobile phase; Mass spectrometry; Plazomicin (ACHN 490); RP HPLC

Indexed keywords

ACETONITRILE; AMMONIUM HYDROXIDE; PLAZOMICIN; WATER;

ARTICLE; COLUMN CHROMATOGRAPHY; DRUG DEGRADATION; DRUG DETERMINATION; DRUG IMPURITY; DRUG PURITY; PH; PRIORITY JOURNAL; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; ULTRAVIOLET SPECTROSCOPY;

ANTI-BACTERIAL AGENTS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DRUG CONTAMINATION; HYDROGEN-ION CONCENTRATION; LIMIT OF DETECTION; MASS SPECTROMETRY; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; SISOMICIN;

EID: 84861224930     PISSN: 07317085     EISSN: 1873264X     Source Type: Journal    
DOI: 10.1016/j.jpba.2012.03.003     Document Type: Article

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