Brain-derived neurotrophic factor Val66Met polymorphism and obsessive-compulsive symptoms in Egyptian schizophrenia patients

Journal of Psychiatric Research

Volumn 46, Issue 6, 2012, Pages 762-766

  Hashim, Haytham M ^a   Fawzy, Nagy ^a   Fawzi, Mohab M ^a   Karam, Rehab A ^a  

^a ZAGAZIG UNIVERSITY   (Egypt)

Author keywords

Brain derived neurotrophic factor; Obsessive compulsive symptoms; Schizophrenia

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR;

ADULT; ARTICLE; CONTROLLED STUDY; DISEASE SEVERITY; DNA POLYMORPHISM; FEMALE; GENOTYPE; HUMAN; MAJOR CLINICAL STUDY; MALE; OBSESSIVE COMPULSIVE DISORDER; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; RATING SCALE; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; SCHIZOPHRENIA; YALEE BROWN OBSESSIVE COMPULSIVE SCALE;

EID: 84861220863     PISSN: 00223956     EISSN: 18791379     Source Type: Journal    
DOI: 10.1016/j.jpsychires.2012.03.007     Document Type: Article

References (48)

1. Andreasen N.C., Endicott J., Spitzer R.L., Winokur G. The family history method using diagnostic criteria. Reliability and validity. Archives of General Psychiatry 1977, 34(10):1229-1235.
2. Angelucci F., Mathe A.A., Aloe L. Brain-derived neurotrophic factor and tyrosine kinase receptor TRKB in rat brain are significantly altered after haloperidol and risperidone administration. Journal of Neuroscience Research 2000, 60:783-794.
3. Berman A., Merson A., Viegner B., Losonczy M.F., Pappas D., Green A.I. Obsessions and compulsions as a distinct cluster of symptoms in schizophrenia: a neuropsychological study. Journal of Nervous and Mental Disease 1998, 186:150-156.
4. Berman I., Kalinowski A., Berman S.M., Lengua J., Green A.I. Obsessive and compulsive symptoms. in schizophrenia. Comprehensive Psychiatry 1995, 36:6-10.
5. Berrios G.E. Obsessive-compulsive disorder: its conceptual history in France during the 19th century. Comprehensive Psychiatry 1989, 30:283-295.
6. Blacker D. Psychiatric rating scales. Kaplan and Sadock's Comprehensive Textbook of Psychiatry 2000, 755-783. Lippincott Williams and Wilkins, Philadelphia. B.J. Sadock, V.A. Sadock (Eds.).
7. Chang H.A., Lu R.B., Shy M.J., Chang C.C., Lee M.S., Huang S.Y. Brain-derived neurotrophic factor Val66Met polymorphism: association with psychopathological symptoms of schizophrenia?. The Journal of Neuropsychiatry and Clinical Neurosciences 2009, 21:30-37.
8. Chen Q.Y., Chen Q., Feng G.Y., Wan C.L., Lindpaintner K., Wang L.J., et al. Association between the brain derived neurotrophic factor (BDNF) gene and schizophrenia in the Chinese population. Neuroscience Letters 2006, 397:285-290.
9. Durany N., Michel T., Zöchling R., Boissl K.W., Cruz-Sánchez F.F., Riederer P., et al. Brain-derived neurotrophic factor and neurotrophin 3 in schizophrenic psychoses. Schizophrenia Research 2001, 52(1-2):79-86.
10. de Haan L., Beuk N., Hoogenboom B., Dingemans P., Linszen D. Obsessive-compulsive symptoms during treatment with olanzapine and risperidone: a prospective study of 113 patients with recent-onset schizophrenia or related disorders. Journal of Clinical Psychiatry 2002, 63(2):104-107.
11. Egan M.F., Kojima M., Callicott J.H., Goldberg T.E., Kolachana B.S., Bertolino A., et al. The BDNF Val66Met polymorphism affects activity-dependent secretion of BDNF and human memory and hippocampal function. Cell 2003, 112:257-269.
12. Fanous A.H., Kendler K.S. Genetic heterogeneity, modifier genes, and quantitative phenotypes in psychiatric illness: searching for a framework. Molecular Psychiatry 2005, 10:6-13.
13. Fawzi M.H., Fawzi M.M., Khedr H.H., Fawzi M.M. Tobacco smoking in Egyptian schizophrenia patients with and without obsessive-compulsive symptoms. Schizophrenia Research 2007, 95:236-246.
14. Goodman W.K., Price L.H., Rasmussen S.A., Mazure C., Fleischmann R.L., Hill C.L., et al. The Yale-Brown obsessive compulsive scale I: development, use and reliability. Archives of General Psychiatry 1989, 46(11):1006-1011.
15. Guillin O., Griffon N., Bezard E., Leriche L., Diaz J., Gross C., et al. BDNF controls dopamine D3 receptor expression and triggers behavioral sensitization. Nature 2001, 411:86-89.
16. Guillin O., Griffon N., Bezard E., et al. Brain-derived neurotrophic factor controls dopamine D3 receptor expression: therapeutic implications in Parkinson's disease. European Journal of Pharmacology 2003, 480(1-3):89-95.
17. Hall D., Dhilla A., Charalambous A., Gogos J.A., Karayiorgou M. Sequence variants of the brain-derived neurotrophic factor (BDNF) gene are strongly associated with obsessive compulsive disorder. American Journal of Human Genetics 2003, 73:370-376.
18. Hanson I.M., Seawright A., van Heyningen V. The human BDNF gene maps between FSHB and HVBS1 at the boundary of 11p13-p14. Genomics 1992, 13:1331-1333.
19. Helen M., Hung-Teh Kao Chao, Porton Barbara BDNF Val66Met variant and age of onset in schizophrenia. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics 2008, 147B(4):505-506.
20. Hemmings S.M., Kinnear C.J., Van der Merwe L., Lochner C., Corfield V.A., Moolman-Smook J.C., et al. Investigating the role of the brain-derived neurotrophic factor (BDNF) val66met variant in obsessive-compulsive disorder (OCD). The World Journal of Biological Psychiatry 2008, 9(2):126-134.
21. Hennigan A., O'Callaghan R.M., Kelly A.M. Neurotrophins and their receptors: roles in plasticity, neurodegeneration and neuroprotection. Biochemical Society Transactions 2007, 35:424-427.
22. Katerberg H., Lochner C., Cath D.C., de Jonge P., Bochdanovits Z., Moolman-Smook J.C., et al. The role of the Brain-Derived Neurotrophic Factor (BDNF) val66met variant in the phenotypic expression of Obsessive-Compulsive Disorder (OCD). American Journal of Medical Genetics Part B 2009, 150B(8):1050-1062.
23. Kayahan B., Ozturk O., Veznedaroglu B., Eraslan D. Obsessive-compulsive symptoms in schizophrenia: prevalence and clinical correlates. Psychiatry and Clinical Neurosciences 2005, 59(3):291-295.
24. Levine E.S., Kolb J.E. Brain-derived neurotrophic factor increases activity of NR2B-containing N-methyl-D-aspartate receptors in excised patches from hippocampal neurons. Journal of Neuroscience Research 2000, 62:357-362.
25. Lysaker P.H., Marks K.A., Picone J.B., Rollins A.L., Fastenau P.S., Bond G.R. Obsessive and compulsive symptoms in schizophrenia: clinical and neurocognitive correlates. Journal of Nervous and Mental Disease 2000, 188(2):78-83.
26. Lysaker P.H., Bryson G.J., Marks K.A., Greig T.C., Bell M.D. Association of obsessions and compulsions in schizophrenia with neurocognition and negative symptoms. Journal of Neuropsychiatry and Clinical Neurosciences 2002, 14(4):449-453.
27. Lysaker P.H., Lancaster R.S., Nees M.A., Davis L.W. Patterns of obsessive-compulsive symptoms and social function in schizophrenia. Psychiatry Research 2004, 125(2):139-146.
28. Mamounas L.A., Altar C.A., Blue M.E., Kaplan D.R., Tessarollo L., Lyons W.E. BDNF promotes the regenerative sprouting, but not survival, of injured serotonergic axons in the adult rat brain. Journal of Neuroscience 2000, 20:771-782.
29. Mossner R., Walitza S., Lesch K.P., Geller F., Barth N., Remschmidt H., et al. Brain-derived neurotrophic factor V66M polymorphism in childhood-onset obsessive-compulsive disorder. International Journal of Neuropsychopharmacology 2005, 8:133-136.
30. Naoe Y., Shinkai T., Hori H., Fukunaka Y., Utsunomiya K., Sakata S., et al. No association between the brain-derived neurotrophic factor (BDNF) Val66Met polymorphism and schizophrenia in Asian populations: evidence from a case-control study and meta-analysis. Neuroscience Letters 2007, 415(2):108-112.
31. Nasreldin M., Ahmed A., Amer D. Assessment of the quality of life in a sample of Egyptian obsessive-compulsive disorder patients. Egyptian Journal of Psychiatry 2004, 23(2):189-198.
32. Neves-Pereira M., Mundo E., Muglia P., King N., Macciardi F., Kennedy J.L. The brain-derived neurotrophic factor gene confers susceptibility to bipolar disorder: Evidence from a family-based association study. American Journal of Human Genetics 2002, 71(3):651-655.
33. Neves-Pereira M., Cheung J.K., Pasdar A., Zhang F., Breen G., Yates P., et al. BDNF gene is a risk factor for schizophrenia in a Scottish population. Molecular Psychiatry 2005, 10(2):208-212.
34. Niehaus D.J., Koen L., Muller J., Laurent C., Stein D.J., Lochner C., et al. Obsessive compulsive disorder-prevalence in Xhosa-speaking schizophrenia patients. South African Medical Journal 2005, 95(2):120-122.
35. Numata S., Ueno S., Iga J., Yamauchi K., Hongwei S., Ohta K., et al. Brain-Derived Neurotrophic Factor (BDNF) Val66Met polymorphism in schizophrenia is associated with age at onset and symptoms. Neuroscience Letters 2006, 401(1-2):1-5.
36. Okasha A., Lotaief F., Ashour A.M., el Mahalawy N., Seif el Dawla A., el-Kholy G. The prevalence of obsessive compulsive symptoms in a sample of Egyptian psychiatric patients. Encephale 2000, 26(4):1-10.
37. Okasha A., Saad A., Khalil A.H., El Dawla A.S., Yehia N. Phenomenology of obsessive-compulsive disorder: a transcultural study. Comprehensive Psychiatry 1994, 35(3):191-197.
38. Ongur D., Goff D.C. Obsessive-compulsive symptoms in schizophrenia: associated clinical features, cognitive function and medication status. Schizophrenia Research 2005, 75(2-3):349-362.
39. Owen M.J., O'Donovan M., Gottesman I. Psychiatric genetics and genomics 2003, Oxford University Press, Oxford, 247-266.
40. Poyurovsky M., Fuchs C., Weizman A. Obsessive-compulsive disorder in patients with first-episode schizophrenia. American Journal of Psychiatry 1999, 156(12):1998-2000.
41. Ribasés M., Gratacòs M., Armengol L., de Cid R., Badía A., Jiménez L., et al. Met66 in the brain-derived neurotrophic factor (BDNF) precursor is associated with anorexia nervosa restrictive type. Molecular Psychiatry 2003, 8(8):745-751.
42. Rosa A., Cuesta M.J., Fatjó-Vilas M., Peralta V., Zarzuela A., Fañanás L. The Val66Met polymorphism of the brain-derived neurotrophic factor gene is associated with risk for psychosis: evidence from a family-based association study. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics 2006, 141:135-138.
43. Sevincok L., Akoglu A., Arslantas H. Schizo-obsessive and obsessive-compulsive disorder: comparison of clinical characteristics and neurological soft signs. Psychiatry Research 2006, 145(2-3):241-248.
44. Skibinska M., Hauser J., Czerski P.M., Leszczynska-Rodziewicz A., Kosmowska M., Kapelski P., et al. Association analysis of Brain-Derived Neurotrophic Factor (BDNF) gene Val66Met polymorphism in schizophrenia and bipolar affective disorder. World Journal of Biological Psychiatry 2004, 5(4):215-220.
45. Sklar P., Gabriel S.B., McInnis M.G., Bennett P., Lim Y.M., Tsan G., et al. Family-based association study of 76 candidate genes in bipolar disorder: BDNF is a potential risk locus. Molecular Psychiatry 2002, 7(6):579-593.
46. SPSS for Windows Statistical Package for the Social Sciences, version 11.0.1 2001, SPSS Inc., Chicago.
47. Szeszko P.R., Lipsky R., Mentschel C., Robinson D., Gunduz-Bruce H., Sevy S., et al. Brain-derived neurotrophic factor val66met polymorphism and volume of the hippocampal formation. Molecular Psychiatry 2005, 10(7):631-636.
48. Takahashi M., Shirakawa O., Toyooka K., Kitamura N., Hashimoto T., Maeda K., et al. Abnormal expression of brain-derived neurotrophic factor and its receptor in the corticolimbic system of schizophrenic patients. Molecular Psychiatry 2000, 5(3):293-300.