Association of cluster of differentiation 36 gene variant rs1761667 (G>A) with metabolic syndrome in Egyptian adults

Saudi Medical Journal

Volumn 33, Issue 5, 2012, Pages 489-494

  Bayoumy, Nervana M ^a   El Shabrawi, Mohamed M ^b   Hassan, Hamdi H ^b  

^a KING KHALID UNIVERSITY HOSPITAL   (Saudi Arabia)

^b Suez Canal University Faculty of Medicine   (Egypt)

Author keywords

[No Author keywords available]

Indexed keywords

CD36 ANTIGEN;

ADULT; ALLELE; ARTICLE; BLOOD SAMPLING; CASE CONTROL STUDY; CONFIDENCE INTERVAL; CONTROLLED STUDY; DNA EXTRACTION; DYSLIPIDEMIA; EGYPT; FEMALE; GENE CLUSTER; GENETIC VARIABILITY; GENOTYPE; HETEROZYGOTE; HUMAN; HUMAN TISSUE; MAJOR CLINICAL STUDY; MALE; METABOLIC SYNDROME X; REAL TIME POLYMERASE CHAIN REACTION; RISK; SINGLE NUCLEOTIDE POLYMORPHISM; SYSTOLIC BLOOD PRESSURE; WAIST CIRCUMFERENCE;

ADULT; AGE DISTRIBUTION; ALLELES; ANTIGENS, CD36; CASE-CONTROL STUDIES; CLUSTER ANALYSIS; CONFIDENCE INTERVALS; EGYPT; FEMALE; GENETIC PREDISPOSITION TO DISEASE; GENETIC VARIATION; GENOTYPE; HUMANS; INCIDENCE; MALE; METABOLIC SYNDROME X; MIDDLE AGED; ODDS RATIO; POLYMORPHISM, SINGLE NUCLEOTIDE; REAL-TIME POLYMERASE CHAIN REACTION; REFERENCE VALUES; SEX DISTRIBUTION;

EID: 84861210546     PISSN: 03795284     EISSN: 16583175     Source Type: Journal    
DOI: None     Document Type: Article

References (43)

1. Alberti KG, Zimmet P, Shaw J. The metabolic syndrome-a new worldwide definition. Lancet 2005; 366: 1059-1062.
2. Reaven GM. Banting lecture 1988. Role of insulin resistance in human disease. Diabetes 1988; 37: 1595-1607.
3. National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III). Third Report of the National Cholesterol Education Program (NCEP) Expert Panel. Circulation 2002; 106: 3143-3421.
4. Grundy SM, Cleeman JI, Daniels SR, Donato KA, Eckel RH, Franklin BA, et al. Diagnosis and management of the metabolic syndrome: an American Heart Association/National Heart, Lung, and Blood Institute Scientific Statement. Circulation 2005; 112: 2735-2752.
5. Gami AS, Witt BJ, Howard DE, Erwin PJ, Gami LA, Somers VK, et al. Metabolic syndrome and risk of incident cardiovascular events and death: a systematic review and meta-analysis of longitudinal studies. J Am Coll Cardiol 2007; 49: 403-414.
6. Kassi E, Pervanidou P, Kaltsas G, Chrousos G. Metabolic syndrome: definitions and controversies. BMC Medicine 2011; 9: 48-60.
7. Ford ES, Giles WH, Mokdad AH. Increasing prevalence of the metabolic syndrome among U.S. adults. Diabetes Care 2004; 27: 2444-2449.
8. Arikan I, Metintas S, Kalyoncu C, Colak O, Arikan U. Evaluation of metabolic syndrome prevalence in semi-rural areas of Central Anatolia, Turkey. Saudi Med J 2009; 30: 1073-1080.
9. Al-Nozha M, Al-Khadra A, Arafah M, Al-Maatouq M, Khalil M, Khan N, et al. Saudi Med J 2005; 26: 1918-1925.
10. Bamashmoos M, Al-Serouri A, Al-Hoothi E, Ali F, Al-Garradi A, Al-Shormani A, et al. Metabolic syndrome among obese patients attending the medical clinics of the three teaching hospitals at Sana'a City, Yemen. Functional Food in Health and Disease 2011; 6: 214-221.
11. Kelishadi R. Childhood overweight, obesity, and the metabolic syndrome in developing countries. Epidemiol Rev 2007; 29: 62-76.
12. Musaiger AO, Al Hazzaa HM, Al-Qahtani A, Elati J, Ramadan J, AboulElla NA. Strategy to combat obesity and to promote physical activity in Arab countries. Diabetes Metab Syndr Obes 2011; 4: 89-97.
13. Eckel R, Grudy S, Zimmet P. The metabolic syndrome. Lancet 2005; 365: 1415-1428.
14. Collot-Teixeira S, Martin J, McDermott-Roe C, Poston R, McGregor JL. CD36 and macrophages in atherosclerosis. Cardiovasc Res 2007; 75: 468-477.
15. Silverstein RL. Inflammation, atherosclerosis, and arterial thrombosis: role of the scavenger receptor CD36. Cleve Clin J Med 2009; 76 (Suppl 2): S27-S30.
16. Glatz F, Luiken J, Bonen, A. Membrane fatty acid transporters as regulators of lipid metabolism: implications for metabolic disease. Physiol Rev 2010; 90: 367-417.
17. Koonen D, Jensen M, Handberg A. Soluble CD36- a marker of the (pathophysiological) role of CD36 in the metabolic syndrome? Arch Physiol Biochem 2011; 117: 57-63.
18. Yildirim A, Akkus M, Nergiz Y, Yuruker S. Immunohistochemical analysis of CD31, CD36, and CD44 antigens in human omentum. Saudi Med J 2004; 25: 308-312.
19. Febbraio M, Silverstein R. CD36: implications in cardiovascular disease. Int J Biochem Cell Biol 2007; 39: 2012-2030.
20. Thorne R, Mhaidat N, Ralston K, Burns G. CD36 is a receptor for oxidized high density lipoprotein: implications for the development of atherosclerosis. FEBS Lett 2007; 581: 1227-1232.
21. Kontrova K, Zidkova J, Bartos B, Skop V, Sajdok J, Kazdova L. CD36 regulates fatty acid composition and sensitivity to insulin in 3T3-L1 adipocytes. Physiol Res 2007; 56: 493-496.
22. Yamashita S, Hirano K, Kuwasako T. Physiological and pathological roles of a multi-ligand receptor CD36 in atherogenesis; insights from CD36-deficient patients. Mol Cell Biochem 2007; 299: 19-22.
23. Rac M, Safranow K, Poncyljusz W. Molecular basis of human CD36 gene mutations. Mol Med 2007; 13: 288-296.
24. An P, Freedman BI, Hanis CL, Chen YD, Weder AB, Schork NJ, et al. Genome-wide linkage scans for fasting glucose, insulin, and insulin resistance in the National Heart, Lung, and Blood Institute Family Blood Pressure Program: Evidence of linkages to chromosome 7q36 and 19q13 from meta-analysis. Diabetes 2005; 554: 909-914.
25. Arya R, Blangero J, Williams K, Almasy L, Dyer TD, Leach RJ, et al. Factors of insulin resistance syndrome-related phenotypes are linked to genetic locations on chromosomes 6 and 7 in nondiabetic Mexican-Americans. Diabetes 2002; 51: 841-847.
26. Malhotra A, Elbein S, Ng M, Duggirala R, Arya R, Imperatore G, et al. Meta-analysis of genome-wide linkage studies of quantitative lipid traits in families ascertained for type 2 diabetes. Diabetes 2007; 56: 890-896.
27. Monisha B, Sunaina G, Madhukar S, Hemant KB, Agarwal CG. Association of CD36 gene variants rs1761667 (G > A) and rs1527483 (C>T) with Type 2 diabetes in North Indian population. International Journal of Diabetes Mellitus 2010; 2: 179-183.
28. GenBank: Z32764. Protocol designed by ARIC DNA Laboratory: COLLEGEN TYPE 1 RECEPTOR (CD36) TAQMAN; ARIC DNA Lab (10/9/01).
29. Alkharfy M, Al-Daghri N, Al-Attas O, Alokail M, Mohammed A, Vinodson B. Variants of endothelial nitric oxide synthase gene are associated with components of metabolic syndrome in an Arab population. Endocr J 2012; 59: 253-263.
30. Kashiwagi H, Tomiyama Y, Nozaki S, Kiyoi T, Tadokoro S, Matsumoto K. Analysis of genetic abnormalities in types I CD36 deficiency in Japan: identification and cell biological characterization of two novel mutations that cause CD36 deficiency in man. Hum Genet 2001; 108: 459-466.
31. Kintaka T, Tanaka T, Imai M, Adachi I, Narabayashi I, Kitaura Y. CD36 genotype and long-chain fatty acid uptake in the heart. Circ J 2002; 66: 819-825.
32. Love-Gregory L, Sherva R, Schappe T, Qi JS, McCrea J, Klein S, et al. Common CD36 SNPs reduce protein expression and may contribute to a protective atherogenic profile. Hum Mol Genet 2011; 20:193-201.
33. Lepretre F, Linton K, Lacquemant C, Vatin V, Samson C, Dina C. Genetic study of the CD36 gene in a French diabetic population. Diab Metab 2004; 30: 459-463.
34. Love-Gregory L, Sherva R, Sun L, Wasson J, Schappe T, Doria A, et al. Variants in the CD36 gene associate with the metabolic syndrome and high density lipoprotein cholesterol. Hum Mol Genet 2008; 17:1695-1704.
35. Noel S, Lai C, Mattei J, Parnell L, Ordovas J, Tuker K. Variants of the CD36 Gene and Metabolic Syndrome in Boston Puerto Rican Adults. Atherosclerosis 2010; 211: 210-215.
36. Ma X, Bacci S, Mlynarski W, Gottardo L, Soccio T, Menzaghi C. A common haplotype at the CD36 locus is associated with high free fatty acid levels and increased cardiovascular risk in Caucasians. Hum Mol Genet 2004; 13: 2197-2205.
37. Zadeh-Vakili A, Faam B, Daneshpour MS, Hedayati M, Azizi F. Association of CD36 Gene Variants and Metabolic Syndrome in Iranians. Genet Test Mol Biomarkers 2011 Nov 2 [Epub ahead of print]
38. Goyenechea E, Collins LJ, Parra D, Liu G, Snieder H, Swaminathan R, et al. CD36 gene promoter polymorphisms are associated with low density lipoproteincholesterol in normal twins and after a low-calorie diet in obese subjects. Twin Res Hum Genet 2008; 11: 621-628.
39. Corpeleijn E, van der Kallen C, Kruijshoop M, Magagnin M, de Bruin T, Feskens E. Direct association of a promoter polymorphism in the CD36/FAT fatty acid transporter gene with Type 2 diabetes mellitus and insulin resistance. Diab Med 2006; 23: 907-911.
40. Kashyap S, Ioachimescu A, Gornik H, Gopan T, Davidson M, Makdissi A. Lipid-induced insulin resistance is associated with increased monocyte expression of scavenger receptor CD36 and internalization of oxidized LDL. Obesity (Silver Spring) 2009; 17: 2142-2148.
41. Koonen D, Jacobs R, Febbraio M, Young M, Soltys C, Ong H, et al. Increased hepatic CD36 expression contributes to dyslipidemia associated with diet-induced obesity. Diabetes 2007; 56: 2863-2871.
42. Louis G, Bruno P, Frédéique T, Kathy B, Bertrand J, Athanase B. Recent advances in metabolic syndrome and cardiovascular disease. Cardiovasc Dis 2008; 101: 577-583.
43. Pravenec M, Kurtz T. Molecular genetics of experimental hypertension and the metabolic syndrome: from gene pathways to new therapies. Hypertension 2007; 49: 941-952.