Selective Gαi subunits as novel direct activators of transient receptor potential canonical (TRPC)4 and TRPC5 channels

Journal of Biological Chemistry

Volumn 287, Issue 21, 2012, Pages 17029-17039

  Jeon, Jae Pyo ^a   Hong, Chansik ^a   Park, Eun Jung ^a   Jeon, Ju Hong ^a   Cho, Nam Hyuk ^a   Kim, In Gyu ^a   Choe, Han ^b   Muallem, Shmuel ^c   Kim, Hyun Jin ^d   So, Insuk ^a  

^a Seoul National University College of Medicine   (South Korea)

^b University of Ulsan College of Medicine   (South Korea)

^c NATIONAL INSTITUTES OF HEALTH   (United States)

^d Sungkyunkwan University School of Medicine   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

C TERMINUS; CELLULAR FUNCTION; CONSTITUTIVELY ACTIVES; DIRECT INTERACTIONS; G PROTEIN; MOLECULAR MECHANISM; PERMEABLE CHANNELS; STRUCTURAL MODELING; TRANSIENT RECEPTOR POTENTIALS;

PROTEINS;

AMINO ACIDS;

G ALPHA I 2 SUBUNIT PROTEIN; G ALPHA I 3 SUBUNIT PROTEIN; G ALPHA Q SUBUNIT PROTEIN; G PROTEIN COUPLED RECEPTOR; MUSCARINIC M2 RECEPTOR; TRANSIENT RECEPTOR POTENTIAL CHANNEL 4; TRANSIENT RECEPTOR POTENTIAL CHANNEL 5; UNCLASSIFIED DRUG;

AMINO ACID COMPOSITION; ANIMAL TISSUE; ARTICLE; CARBOXY TERMINAL SEQUENCE; CHANNEL GATING; CONTROLLED STUDY; EMBRYO; HUMAN; HUMAN CELL; MOLECULAR DYNAMICS; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; PROTEIN SUBUNIT; RAT; STRUCTURE ACTIVITY RELATION;

GTP-BINDING PROTEIN ALPHA SUBUNIT, GI2; GTP-BINDING PROTEIN ALPHA SUBUNITS, GQ-G11; HEK293 CELLS; HUMANS; MUTATION; PROTEIN STRUCTURE, TERTIARY; RECEPTOR, MUSCARINIC M2; TRPC CATION CHANNELS;

EID: 84861207858     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M111.326553     Document Type: Article

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