Evaluation of polymorphisms in EWSR1 and risk of Ewing sarcoma: A report from the childhood cancer survivor study

Pediatric Blood and Cancer

Volumn 59, Issue 1, 2012, Pages 52-56

  Dubois, Steven G ^a   Goldsby, Robert ^a   Segal, Mark ^a   Woo, Jonathan ^a   Copren, Kirsten ^b   Kane, John P ^a   Pullinger, Clive R ^c   Matthay, Katherine K ^a   Witte, John ^a   Lessnick, Stephen L ^d   Robison, Leslie L ^e   Bhatia, Smita ^f   Strong, Louise C ^g  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d UNIVERSITY OF UTAH   (United States)

^e ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

^f MD Anderson Cancer Center ^*  (United States)

^g UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

Author keywords

Ewing sarcoma; EWSR1; Genetic epidemiology; Single nucleotide polymorphism

Indexed keywords

DNA; RNA BINDING PROTEIN EWS; RNA BINDING PROTEIN EWSR1; UNCLASSIFIED DRUG;

AFRICAN AMERICAN; ARTICLE; CANCER DIAGNOSIS; CANCER RISK; CANCER SURVIVOR; CONTROLLED STUDY; EWING SARCOMA; GENE FREQUENCY; GENE LINKAGE DISEQUILIBRIUM; GENE SEQUENCE; GENETIC VARIABILITY; GENOTYPING TECHNIQUE; HUMAN; INTRON; MAJOR CLINICAL STUDY; NEPHROBLASTOMA; PRIORITY JOURNAL; SINGLE NUCLEOTIDE POLYMORPHISM;

ADOLESCENT; ALLELES; BONE NEOPLASMS; CALMODULIN-BINDING PROTEINS; CHILD; CHILD, PRESCHOOL; FEMALE; FOLLOW-UP STUDIES; GENE FREQUENCY; GENETIC PREDISPOSITION TO DISEASE; HUMANS; INTRONS; MALE; POLYMORPHISM, SINGLE NUCLEOTIDE; REGISTRIES; RETROSPECTIVE STUDIES; RISK FACTORS; RNA-BINDING PROTEINS; SARCOMA, EWING; WILMS TUMOR;

EID: 84861206432     PISSN: 15455009     EISSN: 15455017     Source Type: Journal    
DOI: 10.1002/pbc.23263     Document Type: Article

References (21)

1. Gurney JG, Swensen AR, Bulterys M. Malignant bone tumors. In: Ries L, Smith M, Gurney JG, et al., editors. Cancer incidence and survival among children and adolescents: United StatesSEER Program 1975-1995. Bethesda: National Cancer Institute; 1999. pp. 99-110.
2. Hutter RV, Francis KC, Foote FW Jr. Ewing's sarcoma in siblings: Report of the second known occurrence. Am J Surg 1964; 107: 598-603.
3. Joyce MJ, Harmon DC, Mankin HJ, et al. Ewing's sarcoma in female siblings. A clinical report and review of the literature. Cancer 1984; 53: 1959-1962.
4. Zamora P, Garcia de Paredes ML, Gonzalez Baron M, et al. Ewing's tumor in brothers. An unusual observation. Am J Clin Oncol 1986; 9: 358-360.
5. Delattre O, Zucman J, Melot T, et al. The Ewing family of tumors-A subgroup of small-round-cell tumors defined by specific chimeric transcripts. N Engl J Med 1994; 331: 294-299.
6. Arvand A, Denny CT. Biology of EWS/ETS fusions in Ewing's family tumors. Oncogene 2001; 20: 5747-5754.
7. Teitell MA, Thompson AD, Sorensen PH, et al. EWS/ETS fusion genes induce epithelial and neuroectodermal differentiation in NIH 3T3 fibroblasts. Lab Invest 1999; 79: 1535-1543.
8. Thompson AD, Teitell MA, Arvand A, et al. Divergent Ewing's sarcoma EWS/ETS fusions confer a common tumorigenic phenotype on NIH3T3cells. Oncogene 1999; 18: 5506-5513.
9. Delattre O, Zucman J, Plougastel B, et al. Gene fusion with an ETS DNA-binding domain caused by chromosome translocation in human tumours. Nature 1992; 359: 162-165.
10. Zucman J, Delattre O, Desmaze C, et al. Cloning and characterization of the Ewing's sarcoma and peripheral neuroepithelioma t(11;22) translocation breakpoints. Genes Chromosomes Cancer 1992; 5: 271-277.
11. Zucman J, Melot T, Desmaze C, et al. Combinatorial generation of variable fusion proteins in the Ewing family of tumours. EMBO J 1993; 12: 4481-4487.
12. Zucman-Rossi J, Batzer MA, Stoneking M, et al. Interethnic polymorphism of EWS intron 6: Genome plasticity mediated by Alu retroposition and recombination. Hum Genet 1997; 99: 357-363.
13. Robison LL, Armstrong GT, Boice JD, et al. The Childhood Cancer Survivor Study: A National Cancer Institute-supported resource for outcome and intervention research. J Clin Oncol 2009; 27: 2308-2318.
14. Ginsberg JP, Goodman P, Leisenring W, et al. Long-term survivors of childhood Ewing sarcoma: Report from the childhood cancer survivor study. J Natl Cancer Inst 2010; 102: 1272-1283.
15. Gurney JG, Severson RK, Davis S, et al. Incidence of cancer in children in the United States. Sex-, race-, and 1-year age-specific rates by histologic type. Cancer 1995; 75: 2186-2195.
16. Linabery AM, Ross JA, Trends in childhood cancer incidence in the U.S. (1992-2004). Cancer 2008; 112: 416-432.
17. Zamar D, McNeney B, Graham J, elrm: Software implementing exact-like inference for logistic regression models. J Stat Softw 2007; 21: 1-18.
18. R: A language and environment for statistical computing. Vienna: R Foundation for Statistical Computing; 2008.
19. Dabney A, Storey JD, Warnes GR. Q-value estimation for false discovery rate control. R package version 1.1.
20. Storey JD, Tibshirani R. Statistical significance for genomewide studies. Proc Natl Acad Sci USA 2003; 100: 9440-9445.
21. Cui J. GENHWCCI: Stata module to calculate Hardy-Weinberg equilibrium test in case-control studies. Boston College Department of Economics; 2004.