Programmed cell death in Saccharomyces cerevisiae is hampered by the deletion of GUP1 gene

BMC Microbiology

Volumn 12, Issue , 2012, Pages

  Tulha, Joana ^a   Faria Oliveira, Fábio ^a   Lucas, Cndida ^a   Ferreira, Célia ^a  

^a UNIVERSITY OF MINHO   (Portugal)

Author keywords

[No Author keywords available]

Indexed keywords

ACETIC ACID; ACYLTRANSFERASE; FUNGAL ENZYME; GUP1 PROTEIN; PHOSPHATIDYLSERINE; REACTIVE OXYGEN METABOLITE; UNCLASSIFIED DRUG; CARRIER PROTEIN; GUP1 PROTEIN, S CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEIN;

APOPTOSIS; ARTICLE; CHROMATIN CONDENSATION; CHRONOLOGY; CONTROLLED STUDY; FUNGUS MUTANT; GENE DELETION; LIFESPAN; MITOCHONDRIAL MEMBRANE; NONHUMAN; OXIDATIVE STRESS; SACCHAROMYCES CEREVISIAE; WILD TYPE; CELL MEMBRANE; CYTOLOGY; GENETICS; NECROSIS; TIME;

METAZOA; SACCHAROMYCES CEREVISIAE;

ACETIC ACID; APOPTOSIS; GENE DELETION; MEMBRANE MICRODOMAINS; MEMBRANE TRANSPORT PROTEINS; NECROSIS; REACTIVE OXYGEN SPECIES; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; TIME FACTORS;

EID: 84861203343     PISSN: None     EISSN: 14712180     Source Type: Journal    
DOI: 10.1186/1471-2180-12-80     Document Type: Article

References (72)

1. A yeast mutant showing diagnostic markers of early and late apoptosis. Madeo F, Frohlich E, Frohlich KU, J Cell Biol 1997 139 3 729 734 10.1083/jcb.139.3.729 9348289
2. Mammalian Bax triggers apoptotic changes in yeast. Ligr M, Madeo F, Frohlich E, Hilt W, Frohlich KU, Wolf DH, FEBS Lett 1998 438 1-2 61 65 9821959
3. Oxygen stress: a regulator of apoptosis in yeast. Madeo F, Frohlich E, Ligr M, Grey M, Sigrist SJ, Wolf DH, Frohlich KU, J Cell Biol 1999 145 4 757 767 10.1083/jcb.145.4.757 10330404
4. Saccharomyces cerevisiae commits to a programmed cell death process in response to acetic acid. Ludovico P, Sousa MJ, Silva MT, Leao C, Corte-Real M, Microbiology 2001 147 Pt 9 2409 2415 11535781
5. Yeast apoptosis-from genes to pathways. Frohlich KU, Fussi H, Ruckenstuhl C, Semin Cancer Biol 2007 17 2 112 121 10.1016/j.semcancer.2006.11.006 17207637
6. Chronological aging leads to apoptosis in yeast. Herker E, Jungwirth H, Lehmann KA, Maldener C, Frohlich KU, Wissing S, Buttner S, Fehr M, Sigrist S, Madeo F, J Cell Biol 2004 164 4 501 507 10.1083/jcb.200310014 14970189
7. Physiological regulation of yeast cell death in multicellular colonies is triggered by ammonia. Vachova L, Palkova Z, J Cell Biol 2005 169 5 711 717 10.1083/jcb.200410064 15939758
8. Apoptosis in yeast. Madeo F, Herker E, Wissing S, Jungwirth H, Eisenberg T, Frohlich KU, Curr Opin Microbiol 2004 7 6 655 660 10.1016/j.mib.2004.10.012 15556039
9. A caspase-related protease regulates apoptosis in yeast. Madeo F, Herker E, Maldener C, Wissing S, Lachelt S, Herlan M, Fehr M, Lauber K, Sigrist SJ, Wesselborg S, et al. Mol Cell 2002 9 4 911 917 10.1016/S1097-2765(02)00501-4 11983181
10. An AIF orthologue regulates apoptosis in yeast. Wissing S, Ludovico P, Herker E, Buttner S, Engelhardt SM, Decker T, Link A, Proksch A, Rodrigues F, Corte-Real M, et al. J Cell Biol 2004 166 7 969 974 10.1083/jcb.200404138 15381687
11. Endonuclease G regulates budding yeast life and death. Buttner S, Eisenberg T, Carmona-Gutierrez D, Ruli D, Knauer H, Ruckenstuhl C, Sigrist C, Wissing S, Kollroser M, Frohlich KU, et al. Mol Cell 2007 25 2 233 246 10.1016/j.molcel.2006.12.021 17244531
12. The S. cerevisiae HtrA-like protein Nma111p is a nuclear serine protease that mediates yeast apoptosis. Fahrenkrog B, Sauder U, Aebi U, J Cell Sci 2004 117 Pt 1 115 126 14657274
13. The inhibitor-of-apoptosis protein Bir1p protects against apoptosis in S. cerevisiae and is a substrate for the yeast homologue of Omi/HtrA2. Walter D, Wissing S, Madeo F, Fahrenkrog B, J Cell Sci 2006 119 Pt 9 1843 1851 16608876
14. A yeast BH3-only protein mediates the mitochondrial pathway of apoptosis. Buttner S, Ruli D, Vogtle FN, Galluzzi L, Moitzi B, Eisenberg T, Kepp O, Habernig L, Carmona-Gutierrez D, Rockenfeller P, et al. EMBO J 2011 30 14 2779 2792 10.1038/emboj.2011.197 21673659
15. Specific modulation of apoptosis and Bcl-xL phosphorylation in yeast by distinct mammalian protein kinase C isoforms. Saraiva L, Silva RD, Pereira G, Goncalves J, Corte-Real M, J Cell Sci 2006 119 Pt 15 3171 3181 16835272
16. Longevity and aging in the budding yeast. Kaeberlein M, In: Handbook of models for human aging Academic, San Diego, Conn PM, 2006
17. A comparison of the aging and apoptotic transcriptome of Saccharomyces cerevisiae. Laun P, Ramachandran L, Jarolim S, Herker E, Liang P, Wang J, Weinberger M, Burhans DT, Suter B, Madeo F, et al. FEMS Yeast Res 2005 5 12 1261 1272 10.1016/j.femsyr.2005.07.006 16168721
18. Ydc1p ceramidase triggers organelle fragmentation, apoptosis and accelerated ageing in yeast. Aerts AM, Zabrocki P, Francois IE, Carmona-Gutierrez D, Govaert G, Mao C, Smets B, Madeo F, Winderickx J, Cammue BP, et al. Cell Mol Life Sci 2008 65 12 1933 1942 10.1007/s00018-008-8129-8 18500447
19. Ceramide triggers metacaspase-independent mitochondrial cell death in yeast. Carmona-Gutierrez D, Reisenbichler A, Heimbucher P, Bauer MA, Braun RJ, Ruckenstuhl C, Buttner S, Eisenberg T, Rockenfeller P, Frohlich KU, et al. Cell Cycle 2011 10 22 3973 3978 10.4161/cc.10.22.18212 22071627
20. Role for Sit4p-dependent mitochondrial dysfunction in mediating the shortened chronological lifespan and oxidative stress sensitivity of Isc1p-deficient cells. Barbosa AD, Osorio H, Sims KJ, Almeida T, Alves M, Bielawski J, Amorim MA, Moradas-Ferreira P, Hannun YA, Costa V, Mol Microbiol 2011 81 2 515 527 10.1111/j.1365-2958.2011.07714.x 21707788
21. Isc1p plays a key role in hydrogen peroxide resistance and chronological lifespan through modulation of iron levels and apoptosis. Almeida T, Marques M, Mojzita D, Amorim MA, Silva RD, Almeida B, Rodrigues P, Ludovico P, Hohmann S, Moradas-Ferreira P, et al. Mol Biol Cell 2008 19 3 865 876 18162582
22. Biologically active sphingolipids in cancer pathogenesis and treatment. Ogretmen B, Hannun YA, Nat Rev Cancer 2004 4 8 604 616 10.1038/nrc1411 15286740
23. Ceramide involvement in apoptosis and apoptotic diseases. Thevissen K, Francois IE, Winderickx J, Pannecouque C, Cammue BP, Mini Rev Med Chem 2006 6 6 699 709 10.2174/138955706777435643 16787381
24. Lipid rafts: at a crossroad between cell biology and physics. Jacobson K, Mouritsen OG, Anderson RG, Nat Cell Biol 2007 9 1 7 14 10.1038/ncb0107-7 17199125
25. Lipid rafts function in biosynthetic delivery of proteins to the cell surface in yeast. Bagnat M, Keranen S, Shevchenko A, Simons K, Proc Natl Acad Sci U S A 2000 97 7 3254 3259 10.1073/pnas.97.7.3254 10716729
26. Coordination of the dynamics of yeast sphingolipid metabolism during the diauxic shift. Alvarez-Vasquez F, Sims KJ, Voit EO, Hannun YA, Theor Biol Med Model 2007 4 42 10.1186/1742-4682-4-42 17974024
27. Biosynthesis and function of GPI proteins in the yeast Saccharomyces cerevisiae. Pittet M, Conzelmann A, Biochim Biophys Acta 2007 1771 3 405 420 10.1016/j.bbalip.2006.05.015 16859984
28. A superfamily of membrane-bound O-acyltransferases with implications for wnt signaling. Hofmann K, Trends Biochem Sci 2000 25 3 111 112 10.1016/S0968-0004(99)01539-X 10694878
29. Yeast orthologues associated with glycerol transport and metabolism. Neves L, Oliveira R, Lucas C, FEMS Yeast Res 2004 5 1 51 62 10.1016/j.femsyr. 2004.06.012 15381122
30. The yeast O-acyltransferase Gup1p interferes in lipid metabolism with direct consequences on the sphingolipid-sterol-ordered domains integrity/assembly. Ferreira C, Lucas C, Biochim Biophys Acta 2008 1778 11 2648 2653 10.1016/j.bbamem.2008.08.011 18786505
31. GUP1 of Saccharomyces cerevisiae encodes an O-acyltransferase involved in remodeling of the GPI anchor. Bosson R, Jaquenoud M, Conzelmann A, Mol Biol Cell 2006 17 6 2636 2645 10.1091/mbc.E06-02-0104 16597698
32. GUP1 and its close homologue GUP2, encoding multimembrane-spanning proteins involved in active glycerol uptake in Saccharomyces cerevisiae. Holst B, Lunde C, Lages F, Oliveira R, Lucas C, Kielland-Brandt MC, Mol Microbiol 2000 37 1 108 124 10.1046/j.1365-2958.2000.01968.x 10931309
33. Absence of Gup1p in Saccharomyces cerevisiae results in defective cell wall composition, assembly, stability and morphology. Ferreira C, Silva S, van Voorst F, Aguiar C, Kielland-Brandt MC, Brandt A, Lucas C, FEMS Yeast Res 2006 6 7 1027 1038 10.1111/j.1567-1364.2006.00110.x 17042752
34. A lecithin cholesterol acyltransferase-like gene mediates diacylglycerol esterification in yeast. Oelkers P, Tinkelenberg A, Erdeniz N, Cromley D, Billheimer JT, Sturley SL, J Biol Chem 2000 275 21 15609 15612 10.1074/jbc.C000144200 10747858
35. A genomic study of the bipolar bud site selection pattern in Saccharomyces cerevisiae. Ni L, Snyder M, Mol Biol Cell 2001 12 7 2147 2170 11452010
36. A genome-wide screen for Saccharomyces cerevisiae deletion mutants that affect telomere length. Askree SH, Yehuda T, Smolikov S, Gurevich R, Hawk J, Coker C, Krauskopf A, Kupiec M, McEachern MJ, Proc Natl Acad Sci U S A 2004 101 23 8658 8663 10.1073/pnas.0401263101 15161972
37. Identification of an upstream regulatory pathway controlling actin-mediated apoptosis in yeast. Gourlay CW, Ayscough KR, J Cell Sci 2005 118 Pt 10 2119 2132 15855235
38. Inactivation of Cdc13p triggers MEC1-dependent apoptotic signals in yeast. Qi H, Li TK, Kuo D, Nur EKA, Liu LF, J Biol Chem 2003 278 17 15136 15141 10.1074/jbc.M212808200 12569108
39. Cell cycle control of cell death in yeast. Carmona-Gutierrez D, Jungwirth H, Eisenberg T, Madeo F, Cell Cycle 2010 9 20 4046 21058425
40. The chronological life span of Saccharomyces cerevisiae. Fabrizio P, Longo VD, Aging Cell 2003 2 2 73 81 10.1046/j.1474-9728.2003.00033.x 12882320
41. Apoptotic death of ageing yeast. Rockenfeller P, Madeo F, Exp Gerontol 2008 43 10 876 881 10.1016/j.exger.2008.08.044 18782613
42. Vacuolar functions determine the mode of cell death. Schauer A, Knauer H, Ruckenstuhl C, Fussi H, Durchschlag M, Potocnik U, Frohlich KU, Biochim Biophys Acta 2009 1793 3 540 545 10.1016/j.bbamcr.2008.11.006 19100296
43. Changes of the compositional asymmetry of phospholipids associated to the increment in the membrane surface potential. Cerbon J, Calderon V, Biochim Biophys Acta 1991 1067 2 139 144 10.1016/0005-2736(91)90035-7 1878367
44. Early redistribution of plasma membrane phosphatidylserine is a general feature of apoptosis regardless of the initiating stimulus: inhibition by overexpression of Bcl-2 and Abl. Martin SJ, Reutelingsperger CP, McGahon AJ, Rader JA, van Schie RC, LaFace DM, Green DR, J Exp Med 1995 182 5 1545 1556 10.1084/jem.182.5.1545 7595224
45. Mutants in the Saccharomyces cerevisiae RAS2 gene influence life span, cytoskeleton, and regulation of mitosis. Pichova A, Vondrakova D, Breitenbach M, Can J Microbiol 1997 43 8 774 781 10.1139/m97-111 9304788
46. Aged mother cells of Saccharomyces cerevisiae show markers of oxidative stress and apoptosis. Laun P, Pichova A, Madeo F, Fuchs J, Ellinger A, Kohlwein S, Dawes I, Frohlich KU, Breitenbach M, Mol Microbiol 2001 39 5 1166 1173 10.1111/j.1365-2958.2001.02317.x 11251834
47. Cytochrome c release and mitochondria involvement in programmed cell death induced by acetic acid in Saccharomyces cerevisiae. Ludovico P, Rodrigues F, Almeida A, Silva MT, Barrientos A, Corte-Real M, Mol Biol Cell 2002 13 8 2598 2606 10.1091/mbc.E01-12-0161 12181332
48. Superoxide dismutase activity is essential for stationary phase survival in Saccharomyces cerevisiae. Mitochondrial production of toxic oxygen species in vivo. Longo VD, Gralla EB, Valentine JS, J Biol Chem 1996 271 21 12275 12280 10.1074/jbc.271.21.12275 8647826
49. The influence of oxygen toxicity on yeast mother cell-specific aging. Nestelbacher R, Laun P, Vondrakova D, Pichova A, Schuller C, Breitenbach M, Exp Gerontol 2000 35 1 63 70 10.1016/S0531-5565(99)00087-X 10705040
50. Why yeast cells can undergo apoptosis: death in times of peace, love, and war. Buttner S, Eisenberg T, Herker E, Carmona-Gutierrez D, Kroemer G, Madeo F, J Cell Biol 2006 175 4 521 525 10.1083/jcb.200608098 17101700
51. Yeast as a model to study apoptosis? Fleury C, Pampin M, Tarze A, Mignotte B, Biosci Rep 2002 22 1 59 79 10.1023/A:1016013123094 12418551
52. Apoptosis in yeast: a new model system with applications in cell biology and medicine. Madeo F, Engelhardt S, Herker E, Lehmann N, Maldener C, Proksch A, Wissing S, Frohlich KU, Curr Genet 2002 41 4 208 216 10.1007/s00294-002-0310-2 12172961
53. Sphingolipid functions in Saccharomyces cerevisiae. Dickson RC, Lester RL, Biochim Biophys Acta 2002 1583 1 13 25 10.1016/S1388-1981(02)00210-X 12069845
54. Rafts: a simple way to control apoptosis by subcellular redistribution. Garcia A, Cayla X, Fleischer A, Guergnon J, Alvarez-Franco Canas F, Rebollo MP, Roncal F, Rebollo A, Biochimie 2003 85 8 727 731 10.1016/j.biochi.2003.09.005 14585538
55. Mitochondria-dependent apoptosis in yeast. Pereira C, Silva RD, Saraiva L, Johansson B, Sousa MJ, Corte-Real M, Biochim Biophys Acta 2008 1783 7 1286 1302 10.1016/j.bbamcr.2008.03.010 18406358
56. Genome-wide identification of genes required for yeast growth under imatinib stress: vacuolar H+ATPase function is an important target of this anticancer drug. dos Santos SC, Sa-Correia I, OMICS 2009 13 3 185 198 10.1089/omi.2008.0086 19260806
57. Cell death modalities: classification and pathophysiological implications. Galluzzi L, Maiuri MC, Vitale I, Zischka H, Castedo M, Zitvogel L, Kroemer G, Cell Death Differ 2007 14 7 1237 1243 10.1038/sj.cdd.4402148 17431418
58. Involvement of mitochondria and metacaspase elevation in harpin Pss-induced cell death of Saccharomyces cerevisiae. Sripriya P, Vedantam LV, Podile AR, J Cell Biochem 2009 107 6 1150 1159 10.1002/jcb.22217 19507234
59. A molecular mechanism of chronological aging in yeast. Burtner CR, Murakami CJ, Kennedy BK, Kaeberlein M, Cell Cycle 2009 8 8 1256 1270 10.4161/cc.8.8.8287 19305133
60. Yeast protein expression profile during acetic acid-induced apoptosis indicates causal involvement of the TOR pathway. Almeida B, Ohlmeier S, Almeida AJ, Madeo F, Leao C, Rodrigues F, Ludovico P, Proteomics 2009 9 3 720 732 10.1002/pmic.200700816 19137548
61. Extension of chronological life span in yeast by decreased TOR pathway signaling. Powers RW, Kaeberlein M, Caldwell SD, Kennedy BK, Fields S, Genes Dev 2006 20 2 174 184 10.1101/gad.1381406 16418483
62. Role of mitochondria in the pheromone- and amiodarone- induced programmed death of yeast. Pozniakovsky AI, Knorre DA, Markova OV, Hyman AA, Skulachev VP, Severin FF, J Cell Biol 2005 168 2 257 269 10.1083/jcb.200408145 15657396
63. Crucial mitochondrial impairment upon CDC48 mutation in apoptotic yeast. Braun RJ, Zischka H, Madeo F, Eisenberg T, Wissing S, Buttner S, Engelhardt SM, Buringer D, Ueffing M, J Biol Chem 2006 281 35 25757 25767 10.1074/jbc. M513699200 16822868
64. The mitochondrial pathway in yeast apoptosis. Eisenberg T, Buttner S, Kroemer G, Madeo F, Apoptosis 2007 12 5 1011 1023 10.1007/s10495-007-0758-0 17453165
65. Superoxide is a mediator of an altruistic aging program in Saccharomyces cerevisiae. Fabrizio P, Battistella L, Vardavas R, Gattazzo C, Liou LL, Diaspro A, Dossen JW, Gralla EB, Longo VD, J Cell Biol 2004 166 7 1055 1067 10.1083/jcb.200404002 15452146
66. Necrosis, a well-orchestrated form of cell demise: signalling cascades, important mediators and concomitant immune response. Festjens N, Vanden Berghe T, Vandenabeele P, Biochim Biophys Acta 2006 1757 9-10 1371 1387 16950166
67. Lipid rafts and clusters of apoptotic signaling molecule-enriched rafts in cancer therapy. Mollinedo F, Gajate C, Future Oncol 2010 6 5 811 821 10.2217/fon.10.34 20465392
68. The antitumor ether lipid ET-18-OCH(3) induces apoptosis through translocation and capping of Fas/CD95 into membrane rafts in human leukemic cells. Gajate C, Mollinedo F, Blood 2001 98 13 3860 3863 10.1182/blood.V98.13. 3860 11739199
69. Segregation of Bad from lipid rafts is implicated in the induction of apoptosis. Ayllon V, Fleischer A, Cayla X, Garcia A, Rebollo A, J Immunol 2002 168 7 3387 3393 11907096
70. Elevated recombination rates in transcriptionally active DNA. Thomas BJ, Rothstein R, Cell 1989 56 4 619 630 10.1016/0092-8674(89)90584-9 2645056
71. Sherman F, Getting started with yeast. Methods Enzymol 2002 350 3 41
72. YCA1 participates in the acetic acid induced yeast programmed cell death also in a manner unrelated to its caspase-like activity. Guaragnella N, Pereira C, Sousa MJ, Antonacci L, Passarella S, Corte-Real M, Marra E, Giannattasio S, FEBS Lett 2006 580 30 6880 6884 10.1016/j.febslet.2006.11.050 17156780