Non-compartmental estimation of pharmacokinetic parameters for flexible sampling designs

Statistics in Medicine

Volumn 31, Issue 11-12, 2012, Pages 1059-1073

  Jaki, Thomas ^a   Wolfsegger, Martin J ^b  

^a LANCASTER UNIVERSITY   (United Kingdom)

^b BAXTER INNOVATIONS GMBH   (Austria)

Author keywords

Area under the concentration time curve; AUC; Non compartmental; PK parameters; Sparse sampling

Indexed keywords

SARTAN DERIVATIVE;

AREA UNDER THE CURVE; ARTICLE; CONTROLLED STUDY; CROSSOVER PROCEDURE; DATA PROCESSING; DRUG BLOOD LEVEL; HUMAN; HUMAN EXPERIMENT; MALE; NONCOMPARTMENTAL APPROACH; NORMAL HUMAN; PLASMA CONCENTRATION-TIME CURVE; SAMPLING; SINGLE DRUG DOSE; STATISTICAL ANALYSIS; STATISTICAL MODEL; STUDY DESIGN;

ANGIOTENSIN II TYPE 1 RECEPTOR BLOCKERS; ANTIHYPERTENSIVE AGENTS; AREA UNDER CURVE; ASIAN CONTINENTAL ANCESTRY GROUP; COMPUTER SIMULATION; HUMANS; MALE; MODELS, STATISTICAL; PHARMACOKINETICS; RESEARCH DESIGN;

EID: 84861189035     PISSN: 02776715     EISSN: 10970258     Source Type: Journal    
DOI: 10.1002/sim.4386     Document Type: Article

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