메뉴 건너뛰기




Volumn 18, Issue 5, 2012, Pages 585-589

Older participants are frequently excluded from Parkinson's disease research

Author keywords

Ageism; Elderly; Exclusion; Parkinson's; Research

Indexed keywords

AGE DISTRIBUTION; ARTICLE; CLINICAL RESEARCH; CLINICAL STUDY; GERIATRIC PATIENT; HUMAN; PARKINSON DISEASE; PATIENT PARTICIPATION; PRIORITY JOURNAL; RESEARCH SUBJECT; SAMPLE SIZE; STATISTICAL ANALYSIS; STUDY DESIGN; SYSTEMATIC REVIEW; WORLD HEALTH ORGANIZATION;

EID: 84861186696     PISSN: 13538020     EISSN: 18735126     Source Type: Journal    
DOI: 10.1016/j.parkreldis.2012.03.003     Document Type: Article
Times cited : (34)

References (22)
  • 1
    • 84861185509 scopus 로고    scopus 로고
    • Prevalence of parkinsonism and Parkinson's disease in Europe: the EUROPARKINSON Collaborative Study. European Community Concerted Action on the Epidemiology of Parkinson's disease
    • De Rijk M., Tzourio C., Breteler M., Dartigues J., Amaducci L., Lopez-Pousa S., et al. Prevalence of parkinsonism and Parkinson's disease in Europe: the EUROPARKINSON Collaborative Study. European Community Concerted Action on the Epidemiology of Parkinson's disease. J Neurol Neurosurg Psychiatry 1997, 6210-6215.
    • (1997) J Neurol Neurosurg Psychiatry , pp. 6210-6215
    • De Rijk, M.1    Tzourio, C.2    Breteler, M.3    Dartigues, J.4    Amaducci, L.5    Lopez-Pousa, S.6
  • 2
    • 33846572874 scopus 로고    scopus 로고
    • Projected number of people with Parkinson disease in the most populous nations, 2005 through 2030
    • Dorsey E.R., Constantinescu R., Thompson J.P., Biglan K.M., Holloway R.G., Kieburtz K., et al. Projected number of people with Parkinson disease in the most populous nations, 2005 through 2030. Neurology 2007, 68(5):384-386.
    • (2007) Neurology , vol.68 , Issue.5 , pp. 384-386
    • Dorsey, E.R.1    Constantinescu, R.2    Thompson, J.P.3    Biglan, K.M.4    Holloway, R.G.5    Kieburtz, K.6
  • 3
    • 9844261160 scopus 로고    scopus 로고
    • Exclusion of elderly people from clinical research: a descriptive study of published reports
    • Bugeja G., Kumar A., Banerjee A.K. Exclusion of elderly people from clinical research: a descriptive study of published reports. Br Med J 1997, 315(7115):1059.
    • (1997) Br Med J , vol.315 , Issue.7115 , pp. 1059
    • Bugeja, G.1    Kumar, A.2    Banerjee, A.K.3
  • 4
    • 0042991391 scopus 로고    scopus 로고
    • Most hospitalized older persons do not meet the enrollment criteria for clinical trials in heart failure
    • Masoudi F.A., Havranek E.P., Wolfe P., Gross C.P., Rathore S.S., Steiner J.F., et al. Most hospitalized older persons do not meet the enrollment criteria for clinical trials in heart failure. Am Heart J 2003, 146(2):250-257.
    • (2003) Am Heart J , vol.146 , Issue.2 , pp. 250-257
    • Masoudi, F.A.1    Havranek, E.P.2    Wolfe, P.3    Gross, C.P.4    Rathore, S.S.5    Steiner, J.F.6
  • 5
    • 0033619959 scopus 로고    scopus 로고
    • Underrepresentation of patients 65 years of age or older in cancer-treatment trials
    • Hutchins L.F., Unger J.M., Crowley J.J., Coltman C.A., Albain K.S. Underrepresentation of patients 65 years of age or older in cancer-treatment trials. N Engl J Med 1999, 341(27):2061-2067.
    • (1999) N Engl J Med , vol.341 , Issue.27 , pp. 2061-2067
    • Hutchins, L.F.1    Unger, J.M.2    Crowley, J.J.3    Coltman, C.A.4    Albain, K.S.5
  • 6
    • 0030729539 scopus 로고    scopus 로고
    • Exclusion of elderly subjects from clinical trials for Parkinson disease
    • Mitchell S.L., Sullivan E.A., Lipsitz L.A. Exclusion of elderly subjects from clinical trials for Parkinson disease. Arch Neurol 1997, 54(11):1393-1398.
    • (1997) Arch Neurol , vol.54 , Issue.11 , pp. 1393-1398
    • Mitchell, S.L.1    Sullivan, E.A.2    Lipsitz, L.A.3
  • 7
    • 79955162230 scopus 로고    scopus 로고
    • The persistent exclusion of older patients from ongoing clinical trials regarding heart failure
    • Cherubini A., Oristrell J., Pla X., Ruggiero C., Ferretti R., Diestre G., et al. The persistent exclusion of older patients from ongoing clinical trials regarding heart failure. Arch Intern Med 2011, 171(6):550-556.
    • (2011) Arch Intern Med , vol.171 , Issue.6 , pp. 550-556
    • Cherubini, A.1    Oristrell, J.2    Pla, X.3    Ruggiero, C.4    Ferretti, R.5    Diestre, G.6
  • 8
    • 79952553710 scopus 로고    scopus 로고
    • Exclusion of older adults and women from recent trials of acute coronary syndromes
    • Dodd K.S., Saczynski J.S., Zhao Y., Goldberg R.J., Gurwitz J.H. Exclusion of older adults and women from recent trials of acute coronary syndromes. J Am Geriatr Soc 2011, 59(3):506-511.
    • (2011) J Am Geriatr Soc , vol.59 , Issue.3 , pp. 506-511
    • Dodd, K.S.1    Saczynski, J.S.2    Zhao, Y.3    Goldberg, R.J.4    Gurwitz, J.H.5
  • 9
    • 0026782559 scopus 로고
    • The exclusion of the elderly and women from clinical trials in acute myocardial infarction
    • Gurwitz J.H., Col N.F., Avorn J. The exclusion of the elderly and women from clinical trials in acute myocardial infarction. J Am Med Assoc 1992, 268(11):1417-1422.
    • (1992) J Am Med Assoc , vol.268 , Issue.11 , pp. 1417-1422
    • Gurwitz, J.H.1    Col, N.F.2    Avorn, J.3
  • 10
    • 0035827865 scopus 로고    scopus 로고
    • Representation of elderly persons and women in published randomized trials of acute coronary syndromes
    • Lee P.Y., Alexander K.P., Hammill B.G., Pasquali S.K., Peterson E.D. Representation of elderly persons and women in published randomized trials of acute coronary syndromes. J Am Med Assoc 2001, 286(6):708-713.
    • (2001) J Am Med Assoc , vol.286 , Issue.6 , pp. 708-713
    • Lee, P.Y.1    Alexander, K.P.2    Hammill, B.G.3    Pasquali, S.K.4    Peterson, E.D.5
  • 12
    • 28044468217 scopus 로고    scopus 로고
    • The causes and effects of socio-demographic exclusions from clinical trials
    • iii-iv, ix-x, 1-152
    • Bartlett C., Doyal L., Ebrahim S., Davey P., Bachmann M., Egger M., et al. The causes and effects of socio-demographic exclusions from clinical trials. Health Technol Assess 2005, 9(38). iii-iv, ix-x, 1-152.
    • (2005) Health Technol Assess , vol.9 , Issue.38
    • Bartlett, C.1    Doyal, L.2    Ebrahim, S.3    Davey, P.4    Bachmann, M.5    Egger, M.6
  • 13
    • 16244409797 scopus 로고    scopus 로고
    • Exclusion of elderly women from published randomized trials of stress incontinence surgery
    • Morse A.N., Labin L.C., Young S.B., Aronson M.P., Gurwitz J.H. Exclusion of elderly women from published randomized trials of stress incontinence surgery. Obstet Gynecol 2004, 104(3):498-503.
    • (2004) Obstet Gynecol , vol.104 , Issue.3 , pp. 498-503
    • Morse, A.N.1    Labin, L.C.2    Young, S.B.3    Aronson, M.P.4    Gurwitz, J.H.5
  • 14
    • 66149192531 scopus 로고    scopus 로고
    • Current guidelines for using angiotensin-converting enzyme inhibitors and angiotensin II-receptor antagonists in chronic kidney disease: is the evidence base relevant to older adults?
    • O'Hare A.M., Kaufman J.S., Covinsky K.E., Landefeld C.S., McFarland L.V., Larson E.B. Current guidelines for using angiotensin-converting enzyme inhibitors and angiotensin II-receptor antagonists in chronic kidney disease: is the evidence base relevant to older adults?. Ann Intern Med 2009, 150(10):717-724.
    • (2009) Ann Intern Med , vol.150 , Issue.10 , pp. 717-724
    • O'Hare, A.M.1    Kaufman, J.S.2    Covinsky, K.E.3    Landefeld, C.S.4    McFarland, L.V.5    Larson, E.B.6
  • 15
    • 84861185587 scopus 로고
    • National Institutes of Health Revitalization Act of 1993 Subtitle B - Clinical Research Equity Regarding Women and Minorities
    • [accessed 10.12.11].
    • National Institutes of Health Revitalization Act of 1993 Subtitle B - Clinical Research Equity Regarding Women and Minorities. National Institutes of Health Website: 1993 [accessed 10.12.11]. http://orwh.od.nih.gov/inclusion/revitalization.pdf.
    • (1993) National Institutes of Health Website
  • 16
    • 0036259144 scopus 로고    scopus 로고
    • Selection of patients may limit the generalizability of results from cancer trials
    • Fosså S.D., Skovlund E. Selection of patients may limit the generalizability of results from cancer trials. Acta Oncol 2002, 41(2):131-137.
    • (2002) Acta Oncol , vol.41 , Issue.2 , pp. 131-137
    • Fosså, S.D.1    Skovlund, E.2
  • 17
    • 0037008041 scopus 로고    scopus 로고
    • Reporting the recruitment process in clinical trials: who are these patients and how did they get there?
    • Gross C.P., Mallory R., Heiat A., Krumholz H.M. Reporting the recruitment process in clinical trials: who are these patients and how did they get there?. Ann Intern Med 2002, 137(1):10-16.
    • (2002) Ann Intern Med , vol.137 , Issue.1 , pp. 10-16
    • Gross, C.P.1    Mallory, R.2    Heiat, A.3    Krumholz, H.M.4
  • 18
    • 70350668391 scopus 로고    scopus 로고
    • Clinical trial participation: are we studying the patients we are trying to treat?
    • Wang O.J., Krumholz H.M. Clinical trial participation: are we studying the patients we are trying to treat?. Eur J Heart Fail 2009, 11(11):1021-1022.
    • (2009) Eur J Heart Fail , vol.11 , Issue.11 , pp. 1021-1022
    • Wang, O.J.1    Krumholz, H.M.2
  • 19
    • 80054910011 scopus 로고    scopus 로고
    • Improving recruitment of older people to research through good practice
    • McMurdo M.E.T., Roberts H., Parker S., Wyatt N., May H., Goodman C., et al. Improving recruitment of older people to research through good practice. Age Ageing 2011, 40(6):659-665.
    • (2011) Age Ageing , vol.40 , Issue.6 , pp. 659-665
    • McMurdo, M.E.T.1    Roberts, H.2    Parker, S.3    Wyatt, N.4    May, H.5    Goodman, C.6
  • 20
    • 0004034867 scopus 로고
    • Food and Drug Administration Web site:, [accessed 10.12.11], Food and Drug Administration
    • Food and Drug Administration Guideline for the study of drugs likely to be used in the elderly 1989, Food and Drug Administration Web site:, [accessed 10.12.11]. http://www.fda.gov/downloads/Drugs/GuidanceComplianceRegulatoryInformation/Guidances/ucm072048.pdf.
    • (1989) Guideline for the study of drugs likely to be used in the elderly
  • 21
    • 84861195297 scopus 로고
    • International Conference on Harmonisation Web site:, [accessed 10.12.11], International Conference on Harmonisation of Technical Requirements for Registration of Pharmaceuticals for Human Use
    • International Conference on Harmonisation of Technical Requirements for Registration of Pharmaceuticals for Human Use Studies in support of special populations: geriatric ICH E7 1994, International Conference on Harmonisation Web site:, [accessed 10.12.11]. http://www.ich.org/fileadmin/Public_Web_Site/ICH_Products/Guidelines/Efficacy/E7_Guideline.pdf.
    • (1994) Studies in support of special populations: geriatric ICH E7
  • 22
    • 70449715643 scopus 로고    scopus 로고
    • Neurology in the elderly: more trials urgently needed
    • Neurology in the elderly: more trials urgently needed. Lancet Neurol 2009, 8(11):969.
    • (2009) Lancet Neurol , vol.8 , Issue.11 , pp. 969


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.