LINGO1 rs9652490 and rs11856808 are not associated with the risk of Parkinson's disease: Results of a meta-analysis

Parkinsonism and Related Disorders

Volumn 18, Issue 5, 2012, Pages 657-659

  Agúndez, José A G ^a   Lorenzo Betancor, Oswaldo ^b,c   Pastor, Pau ^b,c,d   García Martín, Elena ^a   Luengo, Antonio ^e   Alonso Navarro, Hortensia ^f,g   Jiménez Jiménez, Félix Javier ^f,g  

^a UNIVERSITY OF EXTREMADURA   (Spain)

^b UNIVERSITY OF NAVARRA   (Spain)

^c UNIVERSITY CLINIC OF NAVARRA   (Spain)

^d CENTRO DE INVESTIGACIÓN BIOMÉDICA EN RED SOBRE ENFERMEDADES NEURODEGENERATIVAS CIBERNED   (Spain)

^e HOSPITAL UNIVERSITARIO DE LA PRINCESA   (Spain)

^f Hospital Universitario del Sureste de Madrid   (Spain)

^g UNIVERSITY OF ALCALÁ   (Spain)

Author keywords

Genetics; LINGO1 polymorphisms; Meta analysis; Parkinson's disease

Indexed keywords

DOPAMINERGIC NERVE CELL; GENE; GENE FREQUENCY; GENETIC ASSOCIATION; GENETIC HETEROGENEITY; GENETIC RISK; GENETIC SUSCEPTIBILITY; GENETIC VARIABILITY; GENOTYPE; HUMAN; LETTER; LINGO1 GENE; PARKINSON DISEASE; PRIORITY JOURNAL; RISK ASSESSMENT; SINGLE NUCLEOTIDE POLYMORPHISM;

FEMALE; GENETIC PREDISPOSITION TO DISEASE; HUMANS; MALE; MEMBRANE PROTEINS; NERVE TISSUE PROTEINS; ODDS RATIO; PARKINSON DISEASE; POLYMORPHISM, GENETIC; RISK;

EID: 84861182761     PISSN: 13538020     EISSN: 18735126     Source Type: Journal    
DOI: 10.1016/j.parkreldis.2011.09.005     Document Type: Letter

References (5)

1. Inoue H., Lin L., Lee X., Shao Z., Mendes S., Snodgrass-Belt P., et al. Inhibition of the leucine-rich repeat protein LINGO-1 enhances survival, structure, and function of dopaminergic neurons in Parkinson's disease models. Proc Natl Acad Sci USA 2007, 104:14430-14435.
2. Paisan-Ruiz C., Jain S., Evans E.W., Gilks W.P., Simón J., van der Brug M., et al. Cloning of the gene containing mutations that cause PARK8-linked Parkinson's disease. Neuron 2004, 44:595-600.
3. Vilariño-Güell C., Ross O.A., Wider C., Jasinska-Myga B., Cobb S.A., Soto-Ortolaza A.I., et al. LINGO1 rs9652490 is associated with essential tremor and Parkinson disease. Parkinsonism Relat Disord 2010, 16:109-111.
4. Vilariño-Güell C., Wider C., Ross O.A., Jasinska-Myga B., Kachergus J., Cobb S.A., et al. LINGO1 and LINGO2 variants are associated with essential tremor and Parkinson disease. Neurogenetics 2010, 11:401-408.
5. Lorenzo-Betancor O., Samaranch L., García-Martín E., Cervantes S., Agúndez J.A., Jiménez-Jiménez F.J., et al. LINGO1 gene analysis in Parkinson's disease phenotypes. Mov Disord 2011, 26:722-727.