메뉴 건너뛰기




Volumn 12, Issue 4, 2012, Pages 235-241

The impact of host factors on management of hepatitis c virus

Author keywords

Hepatitis c virus; Host factors; Liver diseases

Indexed keywords

2', 5' OLIGOADENYLATE SYNTHETASE; CHOLESTEROL; HOST FACTOR; INSULIN RECEPTOR; INTERLEUKIN 28B; LOW DENSITY LIPOPROTEIN CHOLESTEROL; MYXOVIRUS RESISTANCE PROTEIN A; PEGINTERFERON; PEGINTERFERON ALPHA2A PLUS RIBAVIRIN; RIBAVIRIN; SUPPRESSOR OF CYTOKINE SIGNALING 3; TRIACYLGLYCEROL; UNCLASSIFIED DRUG;

EID: 84861152218     PISSN: 1735143X     EISSN: 17353408     Source Type: Journal    
DOI: 10.5812/hepatmon.5883     Document Type: Article
Times cited : (3)

References (71)
  • 1
    • 0026334457 scopus 로고
    • Nucleotide sequence and mutation rate of the H strain of hepatitis C virus
    • Ogata N, Alter HJ, Miller RH, Purcell RH. Nucleotide sequence and mutation rate of the H strain of hepatitis C virus. Proc Natl Acad Sci U S A. 1991;88(8):3392.
    • (1991) Proc Natl Acad Sci USA , vol.88 , Issue.8 , pp. 3392
    • Ogata, N.1    Alter, H.J.2    Miller, R.H.3    Purcell, R.H.4
  • 3
    • 61549118827 scopus 로고    scopus 로고
    • Nomenclature and numbering of the hepatitis C virus
    • Kuiken C, Simmonds P. Nomenclature and numbering of the hepatitis C virus. Methods Mol Biol. 2009;510:33-53.
    • (2009) Methods Mol Biol , vol.510 , pp. 33-53
    • Kuiken, C.1    Simmonds, P.2
  • 4
    • 84861126676 scopus 로고    scopus 로고
    • Organization WH. Hepatitis C. [updated] Geneva, Switzerland World Health Organization, 2000 WHO fact sheet 164
    • Organization WH. Hepatitis C. [updated] Geneva, Switzerland World Health Organization, 2000 WHO fact sheet 164; Available from: http://www.who.int/mediacentre/factsheets/fs164/en/print.html.
  • 5
    • 0036829652 scopus 로고    scopus 로고
    • Fibrosis and disease progression in hepatitis C
    • Marcellin P, Asselah T, Boyer N. Fibrosis and disease progression in hepatitis C. Hepatology. 2002;36(5 Suppl 1):S47-S56.
    • (2002) Hepatology , vol.36 , Issue.5 SUPPL. 1
    • Marcellin, P.1    Asselah, T.2    Boyer, N.3
  • 6
    • 0030885637 scopus 로고    scopus 로고
    • Natural history of hepatitis C
    • Seef LB. Natural history of hepatitis C. Hepatology. 1997;26(S3):21S-28S.
    • (1997) Hepatology , vol.26 , Issue.S3
    • Seef, L.B.1
  • 7
    • 65449136656 scopus 로고    scopus 로고
    • Diagnosis, management, and treatment of hepatitis C: An update
    • Ghany MG, Strader DB, Thomas DL, Seef LB. Diagnosis, management, and treatment of hepatitis C: an update. Hepatology. 2009;49(4):1335-1374.
    • (2009) Hepatology , vol.49 , Issue.4 , pp. 1335-1374
    • Ghany, M.G.1    Strader, D.B.2    Thomas, D.L.3    Seef, L.B.4
  • 8
    • 1842480410 scopus 로고    scopus 로고
    • Host factors and failure of interferon-alpha treatment in hepatitis C virus
    • Gao B, Hong F, Radaeva S. Host factors and failure of interferon-alpha treatment in hepatitis C virus. Hepatology. 2004;39(4):880-90.
    • (2004) Hepatology , vol.39 , Issue.4 , pp. 880-890
    • Gao, B.1    Hong, F.2    Radaeva, S.3
  • 9
    • 70349564379 scopus 로고    scopus 로고
    • Targeting host factors: A novel rationale for the management of hepatitis C virus
    • Khattab MA. Targeting host factors: a novel rationale for the management of hepatitis C virus. World J Gastroenterol. 2009;15(28):3472-9.
    • (2009) World J Gastroenterol , vol.15 , Issue.28 , pp. 3472-3479
    • Khattab, M.A.1
  • 10
    • 10744220907 scopus 로고    scopus 로고
    • Interferon-stimulated gene expression and hepatitis C viral dynamics during different interferon regimens
    • Asahina Y, Izumi N, Uchihara M, Noguchi O, Nishimura Y, Inoue K, et al. Interferon-stimulated gene expression and hepatitis C viral dynamics during different interferon regimens. J Hepatol. 2003;39(3):421-7.
    • (2003) J Hepatol , vol.39 , Issue.3 , pp. 421-427
    • Asahina, Y.1    Izumi, N.2    Uchihara, M.3    Noguchi, O.4    Nishimura, Y.5    Inoue, K.6
  • 11
    • 2442669165 scopus 로고    scopus 로고
    • Single nucleotide polymorphism of the MxA gene promoter influences the response to interferon monotherapy in patients with hepatitis C viral infection
    • Suzuki F, Arase Y, Suzuki Y, Tsubota A, Akuta N, Hosaka T, et al. Single nucleotide polymorphism of the MxA gene promoter influences the response to interferon monotherapy in patients with hepatitis C viral infection. J Viral Hepat. 2004;11(3):271-6.
    • (2004) J Viral Hepat , vol.11 , Issue.3 , pp. 271-276
    • Suzuki, F.1    Arase, Y.2    Suzuki, Y.3    Tsubota, A.4    Akuta, N.5    Hosaka, T.6
  • 12
    • 1642359820 scopus 로고    scopus 로고
    • Polymorphisms in interferon-induced genes and the outcome of hepatitis C virus infection: Roles of MxA, OAS-1 and PKR
    • Knapp S, Yee LJ, Frodsham AJ, Hennig BJ, Hellier S, Zhang L, et al. Polymorphisms in interferon-induced genes and the outcome of hepatitis C virus infection: roles of MxA, OAS-1 and PKR. Genes Immun. 2003;4(6):411-9.
    • (2003) Genes Immun , vol.4 , Issue.6 , pp. 411-419
    • Knapp, S.1    Yee, L.J.2    Frodsham, A.J.3    Hennig, B.J.4    Hellier, S.5    Zhang, L.6
  • 13
    • 0345448867 scopus 로고    scopus 로고
    • Apolipoprotein E4 allele is associated with poor treatment response in hepatitis C virus (HCV) genotype 1
    • author reply -3
    • Mueller T, Gessner R, Sarrazin C, Graf C, Halangk J, Witt H, et al. Apolipoprotein E4 allele is associated with poor treatment response in hepatitis C virus (HCV) genotype 1. Hepatology. 2003;38(6):1592; author reply -3.
    • (2003) Hepatology , vol.38 , Issue.6 , pp. 1592
    • Mueller, T.1    Gessner, R.2    Sarrazin, C.3    Graf, C.4    Halangk, J.5    Witt, H.6
  • 14
    • 0141924126 scopus 로고    scopus 로고
    • Response to combination therapy with interferon alfa-2a and ribavirin in chronic hepatitis C according to a TNF-alpha promoter polymorphism
    • Schiemann U, Glas J, Torok P, Simperl C, Martin K, Konig A, et al. Response to combination therapy with interferon alfa-2a and ribavirin in chronic hepatitis C according to a TNF-alpha promoter polymorphism. Digestion. 2003;68(1):1-4.
    • (2003) Digestion , vol.68 , Issue.1 , pp. 1-4
    • Schiemann, U.1    Glas, J.2    Torok, P.3    Simperl, C.4    Martin, K.5    Konig, A.6
  • 15
    • 0036172224 scopus 로고    scopus 로고
    • Polymorphisms in the interleu-kin-10, tumor necrosis factor-[alpha], and transforming growth factor-[beta] 1 genes in chronic hepatitis C patients treated with interferon and ribavirin
    • Vidigal PG, Germer JJ, Zein NN. Polymorphisms in the interleu-kin-10, tumor necrosis factor-[alpha], and transforming growth factor-[beta] 1 genes in chronic hepatitis C patients treated with interferon and ribavirin. J Hepatol. 2002;36(2):271-277.
    • (2002) J Hepatol , vol.36 , Issue.2 , pp. 271-277
    • Vidigal, P.G.1    Germer, J.J.2    Zein, N.N.3
  • 16
    • 70349292099 scopus 로고    scopus 로고
    • Genetic variation in IL28B predicts hepatitis C treatment-induced viral clearance
    • Ge D, Fellay J, Thompson AJ, Simon JS, Shianna KV, Urban TJ, et al. Genetic variation in IL28B predicts hepatitis C treatment-induced viral clearance. Nature. 2009;461(7262):399-401.
    • (2009) Nature , vol.461 , Issue.7262 , pp. 399-401
    • Ge, D.1    Fellay, J.2    Thompson, A.J.3    Simon, J.S.4    Shianna, K.V.5    Urban, T.J.6
  • 17
    • 77952693487 scopus 로고    scopus 로고
    • Replicated association between an IL28B gene variant and a sustained response to pegylated interferon and ribavirin
    • McCarthy JJ, Li JH, Thompson A, Suchindran S, Lao XQ, Patel K, et al. Replicated association between an IL28B gene variant and a sustained response to pegylated interferon and ribavirin. Gas-troenterology. 2010;138(7):2307-2314.
    • (2010) Gas-troenterology , vol.138 , Issue.7 , pp. 2307-2314
    • McCarthy, J.J.1    Li, J.H.2    Thompson, A.3    Suchindran, S.4    Lao, X.Q.5    Patel, K.6
  • 18
    • 70349533037 scopus 로고    scopus 로고
    • Genome-wide association of IL28B with response to pegylated interferon-alpha and ribavirin therapy for chronic hepatitis C
    • Tanaka Y, Nishida N, Sugiyama M, Kurosaki M, Matsuura K, Sakamoto N, et al. Genome-wide association of IL28B with response to pegylated interferon-alpha and ribavirin therapy for chronic hepatitis C. Nat Genet. 2009;41(10):1105-1109.
    • (2009) Nat Genet , vol.41 , Issue.10 , pp. 1105-1109
    • Tanaka, Y.1    Nishida, N.2    Sugiyama, M.3    Kurosaki, M.4    Matsuura, K.5    Sakamoto, N.6
  • 19
    • 70349966196 scopus 로고    scopus 로고
    • Genetic variation in IL28B and spontaneous clearance of hepatitis C virus
    • Thomas DL, Thio CL, Martin MP, Qi Y, Ge D, O'Huigin C, et al. Genetic variation in IL28B and spontaneous clearance of hepatitis C virus. Nature. 2009;461(7265):798-801.
    • (2009) Nature , vol.461 , Issue.7265 , pp. 798-801
    • Thomas, D.L.1    Thio, C.L.2    Martin, M.P.3    Qi, Y.4    Ge, D.5    O'Huigin, C.6
  • 20
    • 77954733618 scopus 로고    scopus 로고
    • 1180 A chromosome 19 snp (rs12979860) predicts outcome (evr/svr) in hcv patients treated with interferon, independent of pegylation or ribavirin
    • Asselah T, Essioux L, Marcellin P, Fried MW, Jensen DM, Germer S, et al. 1180 A chromosome 19 snp (rs12979860) predicts outcome (evr/svr) in hcv patients treated with interferon, independent of pegylation or ribavirin. J Hepatol. 2010;52:S456.
    • (2010) J Hepatol , vol.52
    • Asselah, T.1    Essioux, L.2    Marcellin, P.3    Fried, M.W.4    Jensen, D.M.5    Germer, S.6
  • 21
    • 77953881002 scopus 로고    scopus 로고
    • Interleukin-28B polymorphism improves viral kinetics and is the strongest pretreatment predictor of sustained viro-logic response in genotype 1 hepatitis C virus
    • Thompson AJ, Muir AJ, Sulkowski MS, Ge D, Fellay J, Shianna KV, et al. Interleukin-28B polymorphism improves viral kinetics and is the strongest pretreatment predictor of sustained viro-logic response in genotype 1 hepatitis C virus. Gastroenterology. 2010;139(1):120-129 e18.
    • (2010) Gastroenterology , vol.139 , Issue.1 , pp. 120-129
    • Thompson, A.J.1    Muir, A.J.2    Sulkowski, M.S.3    Ge, D.4    Fellay, J.5    Shianna, K.V.6
  • 22
    • 79952463034 scopus 로고    scopus 로고
    • Genes and hepatitis C: Susceptibility, fibrosis progression and response to treatment
    • Romero-Gomez M, Eslam M, Ruiz A, Maraver M. Genes and hepatitis C: susceptibility, fibrosis progression and response to treatment. Liver Int. 2011;31(4):443-460.
    • (2011) Liver Int , vol.31 , Issue.4 , pp. 443-460
    • Romero-Gomez, M.1    Eslam, M.2    Ruiz, A.3    Maraver, M.4
  • 23
    • 84925580987 scopus 로고    scopus 로고
    • An IL28B polymorphism determines treatment response of hepatitis C virus genotype 2 or 3 patients who do not achieve a rapid virologic response
    • Mangia A, Thompson AJ, Santoro R, Piazzolla V, Tillmann HL, Patel K, et al. An IL28B polymorphism determines treatment response of hepatitis C virus genotype 2 or 3 patients who do not achieve a rapid virologic response. Gastroenterology. 2010;139(3):821-827, 7 e1.
    • (2010) Gastroenterology , vol.139 , Issue.3 , pp. 821-827
    • Mangia, A.1    Thompson, A.J.2    Santoro, R.3    Piazzolla, V.4    Tillmann, H.L.5    Patel, K.6
  • 24
    • 79952899824 scopus 로고    scopus 로고
    • Impact of IL28B genotype on the early and sustained virologic response in treatment-nave patients with chronic hepatitis C
    • Stättermayer AF, Stauber R, Hofer H, Rutter K, Beinhardt S, Scherzer TM, et al. Impact of IL28B genotype on the early and sustained virologic response in treatment-nave patients with chronic hepatitis C. Clin Gastroenterol Hepatol. 2011;9(4):344-350.
    • (2011) Clin Gastroenterol Hepatol , vol.9 , Issue.4 , pp. 344-350
    • Stättermayer, A.F.1    Stauber, R.2    Hofer, H.3    Rutter, K.4    Beinhardt, S.5    Scherzer, T.M.6
  • 25
    • 70349290970 scopus 로고    scopus 로고
    • Genomics: Hepatitis C virus gets personal
    • Iadonato SP, Katze MG. Genomics: Hepatitis C virus gets personal. Nature. 2009;461(7262):357-358.
    • (2009) Nature , vol.461 , Issue.7262 , pp. 357-358
    • Iadonato, S.P.1    Katze, M.G.2
  • 26
    • 70349242026 scopus 로고    scopus 로고
    • Peginter-feron alpha-2a (40 kDa) and ribavirin: Comparable rates of sustained virological response in sub-sets of older and younger HCV genotype 1 patients
    • Reddy KR, Messinger D, Popescu M, Hadziyannis SJ. Peginter-feron alpha-2a (40 kDa) and ribavirin: comparable rates of sustained virological response in sub-sets of older and younger HCV genotype 1 patients. J Viral Hepat. 2009;16(10):724-731.
    • (2009) J Viral Hepat , vol.16 , Issue.10 , pp. 724-731
    • Reddy, K.R.1    Messinger, D.2    Popescu, M.3    Hadziyannis, S.J.4
  • 27
    • 67349254235 scopus 로고    scopus 로고
    • Poor response to pegylated interferon and ribavirin in older women infected with hepatitis C virus of genotype 1b in high viral loads
    • Sezaki H, Suzuki F, Kawamura Y, Yatsuji H, Hosaka T, Akuta N, et al. Poor response to pegylated interferon and ribavirin in older women infected with hepatitis C virus of genotype 1b in high viral loads. Dig Dis Sci. 2009;54(6):1317-1324.
    • (2009) Dig Dis Sci , vol.54 , Issue.6 , pp. 1317-1324
    • Sezaki, H.1    Suzuki, F.2    Kawamura, Y.3    Yatsuji, H.4    Hosaka, T.5    Akuta, N.6
  • 28
    • 78951477270 scopus 로고    scopus 로고
    • Direct economic burden of chronic hepatitis C virus in a United States managed care population
    • Davis KL, Mitra D, Medjedovic J, Beam C, Rustgi V. Direct economic burden of chronic hepatitis C virus in a United States managed care population. J Clin Gastroenterol. 2011;45(2):e17-e24.
    • (2011) J Clin Gastroenterol , vol.45 , Issue.2
    • Davis, K.L.1    Mitra, D.2    Medjedovic, J.3    Beam, C.4    Rustgi, V.5
  • 30
    • 0037065523 scopus 로고    scopus 로고
    • Association between hepatitis C virus seropositiv-ity, carotid-artery plaque, and intima-media thickening
    • Ishizaka N, Ishizaka Y, Takahashi E, Tooda E, Hashimoto H, Nagai R, et al. Association between hepatitis C virus seropositiv-ity, carotid-artery plaque, and intima-media thickening. The Lancet. 2002;359(9301):133-135.
    • (2002) The Lancet , vol.359 , Issue.9301 , pp. 133-135
    • Ishizaka, N.1    Ishizaka, Y.2    Takahashi, E.3    Tooda, E.4    Hashimoto, H.5    Nagai, R.6
  • 31
    • 0035897696 scopus 로고    scopus 로고
    • Executive summary of the third report of the National Cholesterol Education Program (NCEP) expert panel on detection, evaluation, and treatment of high blood cholesterol in adults (Adult Treatment Panel III)
    • Commentary A, Interactive F, Page P, Video F. Executive summary of the third report of the National Cholesterol Education Program (NCEP) expert panel on detection, evaluation, and treatment of high blood cholesterol in adults (Adult Treatment Panel III). JAMA. 2001;285(19):2486-2497.
    • (2001) JAMA , vol.285 , Issue.19 , pp. 2486-2497
    • Commentary, A.1    Interactive, F.2    Page, P.3    Video, F.4
  • 32
    • 79960301485 scopus 로고    scopus 로고
    • Insulin resistance and hepatitis C: An evolving story
    • Eslam M, Khattab MA, Harrison SA. Insulin resistance and hepatitis C: an evolving story. Gut. 2011;60(8):1139-1151.
    • (2011) Gut , vol.60 , Issue.8 , pp. 1139-1151
    • Eslam, M.1    Khattab, M.A.2    Harrison, S.A.3
  • 33
    • 29244484291 scopus 로고    scopus 로고
    • Steatosis in chronic hepatitis C: Why does it really matter?
    • Asselah T, Rubbia-Brandt L, Marcellin P, Negro F. Steatosis in chronic hepatitis C: why does it really matter? Gut. 2006;55(1):123-130.
    • (2006) Gut , vol.55 , Issue.1 , pp. 123-130
    • Asselah, T.1    Rubbia-Brandt, L.2    Marcellin, P.3    Negro, F.4
  • 34
    • 38649120719 scopus 로고    scopus 로고
    • Insulin resistance in chronic hepatitis C: Association with genotypes 1 and 4, serum HCV RNA level, and liver fbrosis
    • Moucari R, Asselah T, Cazals-Hatem D, Voitot H, Boyer N, Ripault MP, et al. Insulin resistance in chronic hepatitis C: association with genotypes 1 and 4, serum HCV RNA level, and liver fbrosis. Gastroenterology. 2008;134(2):416-423.
    • (2008) Gastroenterology , vol.134 , Issue.2 , pp. 416-423
    • Moucari, R.1    Asselah, T.2    Cazals-Hatem, D.3    Voitot, H.4    Boyer, N.5    Ripault, M.P.6
  • 35
    • 77956343048 scopus 로고    scopus 로고
    • Insulin resistance predicts rapid virologic response to peginter-feron/ribavirin combination therapy in hepatitis C genotype 4 patients
    • Khattab M, Eslam M, Sharwae MA, Shatat M, Ali A, Hamdy L. Insulin resistance predicts rapid virologic response to peginter-feron/ribavirin combination therapy in hepatitis C genotype 4 patients. Am J Gastroenterol. 2010;105(9):1970-1977.
    • (2010) Am J Gastroenterol , vol.105 , Issue.9 , pp. 1970-1977
    • Khattab, M.1    Eslam, M.2    Sharwae, M.A.3    Shatat, M.4    Ali, A.5    Hamdy, L.6
  • 36
    • 71549129264 scopus 로고    scopus 로고
    • Insulin resistance predicts rapid virological response in non-diabetic, non-cirrhotic genotype 1 HCV patients treated with peginterferon alpha-2b plus ribavirin
    • Grasso A, Malfatti F, Leo PD, Martines H, Fabris P, Toscanini F, et al. Insulin resistance predicts rapid virological response in non-diabetic, non-cirrhotic genotype 1 HCV patients treated with peginterferon alpha-2b plus ribavirin. J Hepatol. 2009;51(6):984-990.
    • (2009) J Hepatol , vol.51 , Issue.6 , pp. 984-990
    • Grasso, A.1    Malfatti, F.2    Leo, P.D.3    Martines, H.4    Fabris, P.5    Toscanini, F.6
  • 38
    • 74049087081 scopus 로고    scopus 로고
    • Whole-body insulin sensitivity index is a highly specific predictive marker for virological response to peginterferon plus ribavirin therapy in chronic hepatitis C patients with genotype 1b and high viral load
    • Mizuta T, Kawaguchi Y, Eguchi Y, Takahashi H, Ario K, Akiyama T, et al. Whole-body insulin sensitivity index is a highly specific predictive marker for virological response to peginterferon plus ribavirin therapy in chronic hepatitis C patients with genotype 1b and high viral load. Digestive diseases and sciences. 2010;55(1):183-189.
    • (2010) Digestive Diseases and Sciences , vol.55 , Issue.1 , pp. 183-189
    • Mizuta, T.1    Kawaguchi, Y.2    Eguchi, Y.3    Takahashi, H.4    Ario, K.5    Akiyama, T.6
  • 39
    • 36549032819 scopus 로고    scopus 로고
    • Insulin resistance and response to therapy in patients infected with chronic hepatitis C virus genotypes 2 and 3
    • Poustchi H, Negro F, Hui J, Cua IHY, Brandt LR, Kench JG, et al. Insulin resistance and response to therapy in patients infected with chronic hepatitis C virus genotypes 2 and 3. J Hepatol. 2008;48(1):28-34.
    • (2008) J Hepatol , vol.48 , Issue.1 , pp. 28-34
    • Poustchi, H.1    Negro, F.2    Hui, J.3    Cua, I.H.Y.4    Brandt, L.R.5    Kench, J.G.6
  • 40
    • 7244243810 scopus 로고    scopus 로고
    • Hepatitis C virus down-regulates insulin receptor substrates 1 and 2 through up-regulation of suppressor of cytokine signaling 3
    • Kawaguchi T, Yoshida T, Harada M, Hisamoto T, Nagao Y, Ide T, et al. Hepatitis C virus down-regulates insulin receptor substrates 1 and 2 through up-regulation of suppressor of cytokine signaling 3. Am J Pathol. 2004;165(5):1499.
    • (2004) Am J Pathol , vol.165 , Issue.5 , pp. 1499
    • Kawaguchi, T.1    Yoshida, T.2    Harada, M.3    Hisamoto, T.4    Nagao, Y.5    Ide, T.6
  • 41
    • 34248671715 scopus 로고    scopus 로고
    • The hepatitis C virus core protein of genotypes 3a and 1b downregulates insulin receptor substrate 1 through genotype specifc mechanisms
    • Pazienza V, Clément S, Pugnale P, Conzelman S, Foti M, Mangia A, et al. The hepatitis C virus core protein of genotypes 3a and 1b downregulates insulin receptor substrate 1 through genotype specifc mechanisms. Hepatology. 2007;45(5):1164-1171.
    • (2007) Hepatology , vol.45 , Issue.5 , pp. 1164-1171
    • Pazienza, V.1    Clément, S.2    Pugnale, P.3    Conzelman, S.4    Foti, M.5    Mangia, A.6
  • 42
    • 41149095973 scopus 로고    scopus 로고
    • Elevated expression and polymorphisms of SOCS3 influence patient response to antiviral therapy in chronic hepatitis C
    • Persico M, Capasso M, Russo R, Persico E, Croce L, Tiribelli C, et al. Elevated expression and polymorphisms of SOCS3 influence patient response to antiviral therapy in chronic hepatitis C. Gut. 2008;57(4):507.
    • (2008) Gut , vol.57 , Issue.4 , pp. 507
    • Persico, M.1    Capasso, M.2    Russo, R.3    Persico, E.4    Croce, L.5    Tiribelli, C.6
  • 43
    • 48449100910 scopus 로고    scopus 로고
    • Virus-induced over-expression of protein phosphatase 2A inhibits insulin signalling in chronic hepatitis C
    • Bernsmeier C, Duong FHT, Christen V, Pugnale P, Negro F, Terrac-ciano L, et al. Virus-induced over-expression of protein phosphatase 2A inhibits insulin signalling in chronic hepatitis C. J Hepa-tol. 2008;49(3):429-440.
    • (2008) J Hepa-tol , vol.49 , Issue.3 , pp. 429-440
    • Bernsmeier, C.1    Duong, F.H.T.2    Christen, V.3    Pugnale, P.4    Negro, F.5    Terrac-Ciano, L.6
  • 44
    • 70349247875 scopus 로고    scopus 로고
    • Sites and mechanisms of insulin resistance in nonobese, nondiabetic patients with chronic hepatitis C
    • Vanni E, Abate ML, Gentilcore E, Hickman I, Gambino R, Cassader M, et al. Sites and mechanisms of insulin resistance in nonobese, nondiabetic patients with chronic hepatitis C. Hepatology. 2009;50(3):697-706.
    • (2009) Hepatology , vol.50 , Issue.3 , pp. 697-706
    • Vanni, E.1    Abate, M.L.2    Gentilcore, E.3    Hickman, I.4    Gambino, R.5    Cassader, M.6
  • 45
    • 0037362931 scopus 로고    scopus 로고
    • IFN-alpha antagonistic activity of HCV core protein involves induction of suppressor of cytokine signaling-3
    • Bode JG, Ludwig S, Ehrhardt C, Albrecht U, Erhardt A, Schaper F, et al. IFN-alpha antagonistic activity of HCV core protein involves induction of suppressor of cytokine signaling-3. FASEB J. 2003;17(3):488-490.
    • (2003) FASEB J , vol.17 , Issue.3 , pp. 488-490
    • Bode, J.G.1    Ludwig, S.2    Ehrhardt, C.3    Albrecht, U.4    Erhardt, A.5    Schaper, F.6
  • 46
    • 33645114359 scopus 로고    scopus 로고
    • Non-response to antiviral therapy is associated with obesity and increased hepatic expression of suppressor of cytokine signalling 3 (SOCS-3) in patients with chronic hepatitis C, viral genotype 1
    • Walsh MJ, Jonsson JR, Richardson MM, Lipka GM, Purdie DM, Clouston AD, et al. Non-response to antiviral therapy is associated with obesity and increased hepatic expression of suppressor of cytokine signalling 3 (SOCS-3) in patients with chronic hepatitis C, viral genotype 1. Gut. 2006;55(4):529-535.
    • (2006) Gut , vol.55 , Issue.4 , pp. 529-535
    • Walsh, M.J.1    Jonsson, J.R.2    Richardson, M.M.3    Lipka, G.M.4    Purdie, D.M.5    Clouston, A.D.6
  • 47
    • 33847016551 scopus 로고    scopus 로고
    • Defective hepatic response to interferon and activation of suppressor of cytokine signaling 3 in chronic hepatitis C
    • Huang Y, Feld JJ, Sapp RK, Nanda S, Lin JH, Blatt LM, et al. Defective hepatic response to interferon and activation of suppressor of cytokine signaling 3 in chronic hepatitis C. Gastroenterology. 2007;132(2):733-744.
    • (2007) Gastroenterology , vol.132 , Issue.2 , pp. 733-744
    • Huang, Y.1    Feld, J.J.2    Sapp, R.K.3    Nanda, S.4    Lin, J.H.5    Blatt, L.M.6
  • 48
    • 69949097469 scopus 로고    scopus 로고
    • Predictive value of suppressor of cytokine signal 3 (SOCS3) in the outcome of interferon therapy in chronic hepatitis C
    • Miyaaki H, Ichikawa T, Nakao K, Matsuzaki T, Muraoka T, Honda T, et al. Predictive value of suppressor of cytokine signal 3 (SOCS3) in the outcome of interferon therapy in chronic hepatitis C. Hepatol Res. 2009;39(9):850-855.
    • (2009) Hepatol Res , vol.39 , Issue.9 , pp. 850-855
    • Miyaaki, H.1    Ichikawa, T.2    Nakao, K.3    Matsuzaki, T.4    Muraoka, T.5    Honda, T.6
  • 49
    • 0033636780 scopus 로고    scopus 로고
    • Decreased IRS-2 and increased SREBP-1c lead to mixed insulin resistance and sensitivity in livers of lipodystro-phic and ob/ob mice
    • Shimomura I, Matsuda M, Hammer RE, Bashmakov Y, Brown MS, Goldstein JL. Decreased IRS-2 and increased SREBP-1c lead to mixed insulin resistance and sensitivity in livers of lipodystro-phic and ob/ob mice. Mol Cell. 2000;6(1):77-86.
    • (2000) Mol Cell , vol.6 , Issue.1 , pp. 77-86
    • Shimomura, I.1    Matsuda, M.2    Hammer, R.E.3    Bashmakov, Y.4    Brown, M.S.5    Goldstein, J.L.6
  • 50
    • 34548316984 scopus 로고    scopus 로고
    • The lipid droplet is an important organelle for hepatitis C virus production
    • Miyanari Y, Atsuzawa K, Usuda N, Watashi K, Hishiki T, Zayas M, et al. The lipid droplet is an important organelle for hepatitis C virus production. Nat cell biol. 2007;9(9):1089-1097.
    • (2007) Nat Cell Biol , vol.9 , Issue.9 , pp. 1089-1097
    • Miyanari, Y.1    Atsuzawa, K.2    Usuda, N.3    Watashi, K.4    Hishiki, T.5    Zayas, M.6
  • 51
    • 77950602195 scopus 로고    scopus 로고
    • Pioglitazone improves virological response to peginterferon 2b/ribavirin combination therapy in hepatitis C genotype 4 patients with insulin resistance
    • Khattab M, Emad M, Abdelaleem A, Eslam M, Atef R, Shaker Y, et al. Pioglitazone improves virological response to peginterferon 2b/ribavirin combination therapy in hepatitis C genotype 4 patients with insulin resistance. Liver Int. 2010;30(3):447-454.
    • (2010) Liver Int , vol.30 , Issue.3 , pp. 447-454
    • Khattab, M.1    Emad, M.2    Abdelaleem, A.3    Eslam, M.4    Atef, R.5    Shaker, Y.6
  • 52
    • 34247209699 scopus 로고    scopus 로고
    • Diabetes mellitus reduces the therapeutic effectiveness of interferon-alpha2b plus ribavirin therapy in patients with chronic hepatitis C
    • Konishi I, Horiike N, Hiasa Y, Tokumoto Y, Mashiba T, Michitaka K, et al. Diabetes mellitus reduces the therapeutic effectiveness of interferon-alpha2b plus ribavirin therapy in patients with chronic hepatitis C. Hepatol Res. 2007;37(5):331-336.
    • (2007) Hepatol Res , vol.37 , Issue.5 , pp. 331-336
    • Konishi, I.1    Horiike, N.2    Hiasa, Y.3    Tokumoto, Y.4    Mashiba, T.5    Michitaka, K.6
  • 53
    • 70450239924 scopus 로고    scopus 로고
    • Diabetes mellitus is associated with impaired response to antiviral therapy in chronic hepatitis C infection
    • Elgouhari HM, Zein CO, Hanouneh I, Feldstein AE, Zein NN. Diabetes mellitus is associated with impaired response to antiviral therapy in chronic hepatitis C infection. Dig Dis Sci. 2009;54(12):2699-2705.
    • (2009) Dig Dis Sci , vol.54 , Issue.12 , pp. 2699-2705
    • Elgouhari, H.M.1    Zein, C.O.2    Hanouneh, I.3    Feldstein, A.E.4    Zein, N.N.5
  • 54
    • 35848962291 scopus 로고    scopus 로고
    • Impact of diabetes mellitus on prognosis of patients infected with hepatitis C virus
    • Kita Y, Mizukoshi E, Takamura T, Sakurai M, Takata Y, Arai K, et al. Impact of diabetes mellitus on prognosis of patients infected with hepatitis C virus. Metabolism. 2007;56(12):1682-1688.
    • (2007) Metabolism , vol.56 , Issue.12 , pp. 1682-1688
    • Kita, Y.1    Mizukoshi, E.2    Takamura, T.3    Sakurai, M.4    Takata, Y.5    Arai, K.6
  • 55
    • 43549124805 scopus 로고    scopus 로고
    • Insulin resistance and diabetes increase fibrosis in the liver of patients with genotype 1 HCV infection
    • Petta S, Camma C, Di Marco V, Alessi N, Cabibi D, Caldarella R, et al. Insulin resistance and diabetes increase fibrosis in the liver of patients with genotype 1 HCV infection. Am J Gastroenterol. 2008;103(5):1136-1144.
    • (2008) Am J Gastroenterol , vol.103 , Issue.5 , pp. 1136-1144
    • Petta, S.1    Camma, C.2    di Marco, V.3    Alessi, N.4    Cabibi, D.5    Caldarella, R.6
  • 56
    • 77950229401 scopus 로고    scopus 로고
    • Association between lipoprotein subfraction profile and the response to hepatitis C treatment in Japanese patients with genotype 1b
    • Mawatari H, Yoneda M, Fujita K, Nozaki Y, Shinohara Y, Sasaki H, et al. Association between lipoprotein subfraction profile and the response to hepatitis C treatment in Japanese patients with genotype 1b. J Viral Hepat. 2010;17(4):274-279.
    • (2010) J Viral Hepat , vol.17 , Issue.4 , pp. 274-279
    • Mawatari, H.1    Yoneda, M.2    Fujita, K.3    Nozaki, Y.4    Shinohara, Y.5    Sasaki, H.6
  • 57
    • 78049315847 scopus 로고    scopus 로고
    • Serum lipids in European chronic HCV genotype 1 patients during and after treatment with pegylated interferon-a-2a and ribavirin
    • Lange CM, von Wagner M, Bojunga J, Berg T, Farnik H, Hassler A, et al. Serum lipids in European chronic HCV genotype 1 patients during and after treatment with pegylated interferon-a-2a and ribavirin. Eur J Gastroenterol Hepatol. 2010;22(11):1303.
    • (2010) Eur J Gastroenterol Hepatol , vol.22 , Issue.11 , pp. 1303
    • Lange, C.M.1    von Wagner, M.2    Bojunga, J.3    Berg, T.4    Farnik, H.5    Hassler, A.6
  • 58
    • 84861126673 scopus 로고    scopus 로고
    • 266 clinical markers of the metabolic syndrome are associated with hcv genotype 1 infection and are strong negative predictors of early virological response
    • S112-S
    • Jaeckel E, Zehnter E, John C, Lutz T, Schmidt W, Link R, et al. 266 clinical markers of the metabolic syndrome are associated with hcv genotype 1 infection and are strong negative predictors of early virological response. J Hepatol. 2010;52:S112-S.
    • (2010) J Hepatol , vol.52
    • Jaeckel, E.1    Zehnter, E.2    John, C.3    Lutz, T.4    Schmidt, W.5    Link, R.6
  • 60
    • 77956646681 scopus 로고    scopus 로고
    • Serum cholesterol and statin use predict virological response to peginterferon and ribavirin therapy
    • Harrison SA, Rossaro L, Hu KQ, Patel K, Tillmann H, Dhaliwal S, et al. Serum cholesterol and statin use predict virological response to peginterferon and ribavirin therapy. Hepatology. 2010;52(3):864-874.
    • (2010) Hepatology , vol.52 , Issue.3 , pp. 864-874
    • Harrison, S.A.1    Rossaro, L.2    Hu, K.Q.3    Patel, K.4    Tillmann, H.5    Dhaliwal, S.6
  • 61
    • 79960382329 scopus 로고    scopus 로고
    • IL28B polymorphisms predict reduction of HCV RNA from the first day of therapy in chronic hepatitis C
    • Bochud PY, Bibert S, Negro F, Haagmans B, Soulier A, Ferrari C, et al. IL28B polymorphisms predict reduction of HCV RNA from the first day of therapy in chronic hepatitis C. J Hepatol. 2011;55(5):980-988.
    • (2011) J Hepatol , vol.55 , Issue.5 , pp. 980-988
    • Bochud, P.Y.1    Bibert, S.2    Negro, F.3    Haagmans, B.4    Soulier, A.5    Ferrari, C.6
  • 62
    • 77952730427 scopus 로고    scopus 로고
    • Interferon lambda genotype and low serum low density lipo-protein cholesterol levels in patients with chronic hepatitis C infection
    • Li JH, Qian Lao X, Tillmann HL, Rowell J, Patel K, Thompson A, et al. Interferon lambda genotype and low serum low density lipo-protein cholesterol levels in patients with chronic hepatitis C infection. Hepatology. 2010;51(6):1904-1911.
    • (2010) Hepatology , vol.51 , Issue.6 , pp. 1904-1911
    • Li, J.H.1    Qian Lao, X.2    Tillmann, H.L.3    Rowell, J.4    Patel, K.5    Thompson, A.6
  • 63
    • 59349094958 scopus 로고    scopus 로고
    • Hepatitis C virus, steatosis and lipid abnormalities: Clinical and pathogenic data
    • Negro F, Sanyal AJ. Hepatitis C virus, steatosis and lipid abnormalities: clinical and pathogenic data. Liver Int. 2009;29(Suppl 2):26-37.
    • (2009) Liver Int , vol.29 , Issue.SUPPL. 2 , pp. 26-37
    • Negro, F.1    Sanyal, A.J.2
  • 64
    • 33646529840 scopus 로고    scopus 로고
    • Relationship between steatosis, inflammation, and f-brosis in chronic hepatitis C: A meta-analysis of individual patient data
    • Leandro G, Mangia A, Hui J, Fabris P, Rubbia-Brandt L, Colloredo G, et al. Relationship between steatosis, inflammation, and f-brosis in chronic hepatitis C: a meta-analysis of individual patient data. Gastroenterology. 2006;130(6):1636-1642.
    • (2006) Gastroenterology , vol.130 , Issue.6 , pp. 1636-1642
    • Leandro, G.1    Mangia, A.2    Hui, J.3    Fabris, P.4    Rubbia-Brandt, L.5    Colloredo, G.6
  • 66
    • 0038122773 scopus 로고    scopus 로고
    • Effect of treatment with peginterferon or interferon alfa 2b and ribavirin on steatosis in patients infected with hepatitis C
    • Poynard T, Ratziu V, McHutchison J, Manns M, Goodman Z, Zeu-zem S, et al. Effect of treatment with peginterferon or interferon alfa 2b and ribavirin on steatosis in patients infected with hepatitis C. Hepatology. 2003;38(1):75-85.
    • (2003) Hepatology , vol.38 , Issue.1 , pp. 75-85
    • Poynard, T.1    Ratziu, V.2    McHutchison, J.3    Manns, M.4    Goodman, Z.5    Zeu-Zem, S.6
  • 67
    • 2442683905 scopus 로고    scopus 로고
    • Peginterferon alfa-2b plus ribavirin for treatment of chronic hepatitis C in previously untreated patients infected with HCV genotypes 2 or 3* 1,* 2
    • Zeuzem S, Hultcrantz R, Bourliere M, Goeser T, Marcellin P, Sanchez-Tapias J, et al. Peginterferon alfa-2b plus ribavirin for treatment of chronic hepatitis C in previously untreated patients infected with HCV genotypes 2 or 3* 1,* 2. J Hepatol. 2004;40(6):993-999.
    • (2004) J Hepatol , vol.40 , Issue.6 , pp. 993-999
    • Zeuzem, S.1    Hultcrantz, R.2    Bourliere, M.3    Goeser, T.4    Marcellin, P.5    Sanchez-Tapias, J.6
  • 68
    • 33845737858 scopus 로고    scopus 로고
    • Impact of hepatic steatosis on viral kinetics and treatment outcome during antiviral treatment of chronic HCV infection
    • Westin J, Lagging M, Dhillon AP, Norkrans G, Romero A, Paw-lotsky JM, et al. Impact of hepatic steatosis on viral kinetics and treatment outcome during antiviral treatment of chronic HCV infection. J Viral Hepat. 2007;14(1):29-35.
    • (2007) J Viral Hepat , vol.14 , Issue.1 , pp. 29-35
    • Westin, J.1    Lagging, M.2    Dhillon, A.P.3    Norkrans, G.4    Romero, A.5    Paw-Lotsky, J.M.6
  • 69
    • 21044456174 scopus 로고    scopus 로고
    • Insulin resistance is a cause of steatosis and fbrosis progression in chronic hepatitis C
    • Fartoux L, Poujol-Robert A, Guechot J, Wendum D, Poupon R, Serfaty L. Insulin resistance is a cause of steatosis and fbrosis progression in chronic hepatitis C. Gut. 2005;54(7):1003.
    • (2005) Gut , vol.54 , Issue.7 , pp. 1003
    • Fartoux, L.1    Poujol-Robert, A.2    Guechot, J.3    Wendum, D.4    Poupon, R.5    Serfaty, L.6
  • 70
    • 79952308232 scopus 로고    scopus 로고
    • Early menopause is associated with lack of response to antiviral therapy in women with chronic hepatitis C
    • Villa E, Karampatou A, Camma C, Di Leo A, Luongo M, Ferrari A, et al. Early menopause is associated with lack of response to antiviral therapy in women with chronic hepatitis C. Gastroenterology. 2011;140(3):818-829.
    • (2011) Gastroenterology , vol.140 , Issue.3 , pp. 818-829
    • Villa, E.1    Karampatou, A.2    Camma, C.3    di Leo, A.4    Luongo, M.5    Ferrari, A.6
  • 71
    • 79956074037 scopus 로고    scopus 로고
    • Management of hepatitis C virus genotype 4: Recommendations of An International Expert Panel
    • Khattab MA, Ferenci P, Hadziyannis SJ, Colombo M, Manns MP, Almasio PL, et al. Management of hepatitis C virus genotype 4: Recommendations of An International Expert Panel. J Hepatol. 2010;54(6):1250-1262.
    • (2010) J Hepatol , vol.54 , Issue.6 , pp. 1250-1262
    • Khattab, M.A.1    Ferenci, P.2    Hadziyannis, S.J.3    Colombo, M.4    Manns, M.P.5    Almasio, P.L.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.