Pharmacokinetic modeling of data with below quantification limit

Journal of Bioequivalence and Bioavailability

Volumn 4, Issue 2, 2012, Pages

  Dorababu, Madhura ^a  

^a UNIVERSITY OF TENNESSEE HEALTH SCIENCE CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AREA UNDER THE CURVE; BODY FLUID; COMPARTMENT MODEL; DRUG ABSORPTION; DRUG DISTRIBUTION; DRUG EFFICACY; DRUG ELIMINATION; DRUG EXPOSURE; DRUG METABOLISM; DRUG SAFETY; EDITORIAL; HUMAN; LIMIT OF QUANTITATION; MAXIMUM LIKELIHOOD METHOD; MONTE CARLO METHOD; PHARMACOKINETICS;

EID: 84861144575     PISSN: None     EISSN: 09750851     Source Type: Journal    
DOI: 10.4172/jbb.10000e12     Document Type: Editorial

References (2)

1. Beal SL (2001) Ways to fit a PK model with some data below the quantification limit. J Pharmacokinet Pharmacodyn 28: 481-504.
2. Yan S, RogerJ (2010) Evaluations of Bayesian and maximum likelihood methods in PK models with below-quantification-limit data. Pharm Stat 9: 313-330.