Treatment of one case of cerebral palsy combined with posterior visual pathway injury using autologous bone marrow mesenchymal stem cells

Journal of Translational Medicine

Volumn 10, Issue 1, 2012, Pages

  Li, Min ^a   Yu, Aixue ^a   Zhang, Fangfang ^a   Dai, GuangHui ^a   Cheng, Hongbin ^a   Wang, Xiaodong ^a   An, Yihua ^a,b  

^a GENERAL HOSPITAL OF CHINESE PEOPLE'S ARMED POLICE FORCES   (China)

^b CAPITAL MEDICAL UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

BETA1 INTEGRIN; CD14 ANTIGEN; CD34 ANTIGEN; CD45 ANTIGEN; HERMES ANTIGEN; HLA DR ANTIGEN; VASCULAR CELL ADHESION MOLECULE 1;

ADOLESCENT; ARTICLE; ASPHYXIA; ATTENTION; AUTOLOGOUS BONE MARROW TRANSPLANTATION; BIRTH; BLOOD EXAMINATION; BRAIN RADIOGRAPHY; CASE REPORT; CEREBRAL PALSY; DISEASE ASSOCIATION; DYSTOCIA; ELECTROCARDIOGRAPHY; EVOKED VISUAL RESPONSE; FOLLOW UP; GAZE; HOSPITAL DISCHARGE; HOSPITALIZATION; HUMAN; KIDNEY FUNCTION TEST; LIVER FUNCTION TEST; MALE; MESENCHYMAL STEM CELL TRANSPLANTATION; NUCLEAR MAGNETIC RESONANCE IMAGING; POSTERIOR VISUAL PATHWAY INJURY; POSTOPERATIVE PERIOD; PREOPERATIVE PERIOD; TREATMENT OUTCOME; VISUAL ACUITY; VISUAL DISORDER;

BONE MARROW CELLS; CEREBRAL PALSY; CHILD; EVOKED POTENTIALS, VISUAL; HUMANS; MAGNETIC RESONANCE IMAGING; MALE; MESENCHYMAL STEM CELL TRANSPLANTATION; TRANSPLANTATION, AUTOLOGOUS; TREATMENT OUTCOME; VISUAL PATHWAYS;

EID: 84861122350     PISSN: None     EISSN: 14795876     Source Type: Journal    
DOI: 10.1186/1479-5876-10-100     Document Type: Article

References (30)

1. Grönqvist S, Flodmark O, Tornqvist K, Edlund G, Hellström A. Association between visual impairment and functional and morphological cerebral abnormalities in full-term children. Acta Ophthalmol 2001, 79:140-146.
2. Dutton GN, Jacobson LK. Cerebral visual impairment in children. Sem Neonatol 2001, 6:477-485.
3. Mercuri E, Atkinson J, Braddick O, Anker S, Cowan F, Rutherford M, Pennock J, Dubowitz L. Basal ganglia damage and impaired visual function in the newborn infant. Arch Dis Child Fetal Neonatal Ed 1997, 77:F111-F114. 10.1136/fn.77.2.F111, 1720693, 9377131.
4. Woodbury D, Schwarz EJ, Prockop DJ, et al. Adult rat and human bone marrow stromal cells differentiate into neurons. J Neurosci Res 2000, 61:364-370. 10.1002/1097-4547(20000815)61:4<364::AID-JNR2>3.0.CO;2-C, 10931522.
5. Woodbury D, Schwarz EJ, Prockop DJ, Black IB. Neurospheres induced from bone marrow stromal cells are multipotent for differentiation into neuron, astrocyte, and oligodendrocyte phenotypes. Biochem Biophys Res Commun 2004, 322:918-922. 10.1016/j.bbrc.2004.07.201, 15336551.
6. Mori T, Kiyono T, Imabayashi H, Takeda Y, Tsuchiya K, Miyoshi S, Makino H, Matsumoto K, Saito H, Ogawa S, Sakamoto M, Hata J, Umezawa A. Combination of hTERT and bmi-1, E6, or E7 induces prolongation of the life span of bone marrow stromal cells from an elderly donor without affecting their neurogenic potential. Mol Cell Biol 2005, 25:5183-5195. 10.1128/MCB.25.12.5183-5195.2005, 1140572, 15923633.
7. Tomita M, Adachi Y, Yamada H, Takahashi K, Kiuchi K, Oyaizu H, Ikebukuro K, Kaneda H, Matsumura M, Ikehara S. Bone marrow-derived stem cells can differentiate into retinal cells in injured rat retina. Stem Cells 2002, 20:279-283. 10.1634/stemcells.20-4-279, 12110696.
8. Kicic A, Shen WY, Wilson AS, Constable IJ, Robertson T, Rakoczy PE. Differentiation of marrow stromal cells into photoreceptors in the rat eye. J Neurosci 2003, 23:7742-7749.
9. Li Y, Chopp M, Chen J, Wang L, Gautam SC, Xu YX, Zhang Z. Intrastriatal transplantation of bone marrow nonhematopoietic cells improves functional recovery after stroke in adult mice. J Cereb Blood Flow Metab 2000, 20:1311-1319. 10.1097/00004647-200009000-00006, 10994853.
10. Guan XQ, Yu JL, Li LQ, Liu GX. Study on mesenchymal stem cells entering the brain through the blood-brian barrier. Zhonghua Er Ke Za Zhi 2004, 42:920-923.
11. Wang L, Li Y, Chen X, Chen J, Gautam SC, Xu Y, Chopp M. MCP-1, MIP, IL-8 and ischemic cerebral tissure enhance the human bone marrow stromal cell migration in interface culture. Hematology 2002, 7:113-117. 10.1080/10245330290028588, 12186702.
12. Dormady SP, Bashayan O, Dougherty R, Zhang XM, Basch RS. Immortalized multipotential mesenchymal cells and the hematopoietic microenvironment. J Hematother Stem Cell Res 2001, 10:125-140. 10.1089/152581601750098372, 11276366.
13. Abe K. Therapeutic potential of neurotrophic factors and neural stem cells against ischemic brain injury. J Cereb Blood Flow Metab 2000, 20:1393-1408.
14. Mahmood A, Lu D, Wang L, Chopp M. Intracerebral transplantation of marrow stromal cells cultured with neurotrophic factors promotes functional recovery in adult rats subjected to traumatic brain injury. J Jeurotrauma 2002, 19:1609-1617.
15. Im GI, Kim DY, Shin JH, Hyun CW, Cho WH. Repair of cartilage defect in the rabbit with cultured mesenchymal stem cells from bone marrow. J Bone Joint Surg Br 2001, 83:289-294. 10.1302/0301-620X.83B2.10495, 11284583.
16. Terada N, Hamazaki T, Oka M, Hoki M, Mastalerz DM, Nakano Y, Meyer EM, Morel L, Petersen BE, Scott EW. Bone marrow cells adopt the phenotype of other cells by spontaneous cell fusion. Nature 2002, 416:542-545. 10.1038/nature730, 11932747.
17. An YH, Wan H, Zhang ZS, Wang HY, Gao ZX, Sun MZ, Wang ZC. Effect of rat Schwann cell secretion on proliferation and differentiation of human neural stem cells. Biomed Environ Sci 2003, 16:90-94.
18. Li Y, Chen J, Chen XG, Wang L, Gautam SC, Xu YX, Katakowski M, Zhang LJ, Lu M, Janakiraman N, Chopp M. Human marrow stromal cell therapy for stroke in rat: neurotrophins and functional recovery. Neurology 2002, 59:514-523. 10.1212/WNL.59.4.514, 12196642.
19. Chen X, Li Y, Wang L, Katakowski M, Zhang L, Chen J, Xu Y, Gautam SC, Chopp M. Ischemic rat brain extracts induce human marrow stromal cell growth factor production. Neuropathology 2002, 22:275-279. 10.1046/j.1440-1789.2002.00450.x, 12564767.
20. Ye M, Chen S, Wang X, Qi C, Lu G, Liang L, Xu J. Glial cell line-derived neurotrophic factor in bone marrow stromal cells of rat. Neuroreport 2005, 16:581-584. 10.1097/00001756-200504250-00013, 15812312.
21. Zhang J, Li Y, Chen J, Cui Y, Lu M, Elias SB, Mitchell JB, Hammill L, Vanguri P, Chopp M. Human bone marrow stromal cell treatment improves neurological functional recovery in EAE mice. Exp Neural 2005, 195:16-26.
22. Mahmood A, Lu D, Qu C, Goussev A, Chopp M. Long-term recovery after bone marrow stramal cell treatment of traumatic brain injury in rats. J Neurosurg 2006, 104:272-277. 10.3171/jns.2006.104.2.272, 16509501.
23. Chen J, Zhang ZG, Li Y, Wang L, Xu YX, Gautam SC, Lu M, Zhu Z, Chopp M. Intravenous administration of human bone marrow stromal cells induces angiogenesis in the ischemic boundary zone after stroke in rats. Circ Res 2003, 92:692-699. 10.1161/01.RES.0000063425.51108.8D, 12609969.
24. Shen LH, Li Y, Chen J, Cui Y, Zhang C, Kapke A, Lu M, Savant-Bhonsale S, Chopp M. One-year follow-up after bone marrow stromal cell treatment in middle-aged female rats with stroke. Stroke 2007, 38:2150-2156. 10.1161/STROKEAHA.106.481218, 17525391.
25. Liu Z, Li Y, Zhang X, Savant-Bhonsale S, Chopp M. Contralesional axonal remodeling of the corticospinal system in adult rats after stroke and bone marrow stromal cell treatment. Stroke 2008, 39:2571-2577. 10.1161/STROKEAHA.107.511659, 2593106, 18617661.
26. Li WY, Choi YJ, Lee PH, Huh K, Kang YM, Kim HS, Ahn YH, Lee G, Bang OY. Mesenchymal stem cells for ischemic stroke: Changes in effects after ex vivo culturing. Cell Transplant 2008, 17:1045-1059. 10.3727/096368908786991551, 19177841.
27. Abrahams JM, Gokhan S, Flamm ES, Mehler MF. De novo neurogenesis and acute stroke: Are exogenous stem cells really necessary?. Neurosurgery 2004, 54:150-156. 10.1227/01.NEU.0000097515.27930.5E, 14683552.
28. Lindvall O, Kokaia Z, Martinez-Serrano A. Stem cell therapy for human neurodegenerative disorders-how to make it work. Nat Med 2004, 10(Suppl):42-50.
29. Kokaia Z, Thored P, Arvidsson A, Lindvall O. Regulation of stroke-induced neurogenesis in adult brain-recent scientific progress. Cereb Cortex 2006, 16(Suppl 1):1162-1167.
30. Zhu J, Zhou L, XingWu F. Tracking neural stem cells in patients with brain trauma. N Engl J Med 2006, 355:2376-2378. 10.1056/NEJMc055304, 17135597.