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Volumn 1, Issue 2, 2010, Pages 85-95

Update on role of chemotherapy in head and neck squamous cell cancer

Author keywords

cetuximab; chemoradiation; chemotherapy; Head and neck cancer; induction chemotherapy; targeted therapy

Indexed keywords

ANTINEOPLASTIC AGENT; BIOLOGICAL PRODUCT; CAPECITABINE; CARBOPLATIN; CETUXIMAB; CISPLATIN; CYCLOPHOSPHAMIDE; CYTOTOXIC AGENT; DOCETAXEL; DOXORUBICIN; EPIDERMAL GROWTH FACTOR RECEPTOR; EPIRUBICIN; ERLOTINIB; FLUOROURACIL; GEFITINIB; GEMCITABINE; HYDROXYUREA; IFOSFAMIDE; IRINOTECAN; LAPATINIB; MATUZUMAB; METHOTREXATE; NIMOTUZUMAB; PACLITAXEL; PANITUMUMAB; PEMETREXED; PLACEBO; PLATINUM DERIVATIVE; TAXANE DERIVATIVE; UNINDEXED DRUG;

EID: 84861113464     PISSN: 09757651     EISSN: 09766952     Source Type: Journal    
DOI: 10.1007/s13193-010-0021-y     Document Type: Review
Times cited : (9)

References (79)
  • 1
    • 33646568784 scopus 로고    scopus 로고
    • Patterns of cancer incidence, mortality, and prevalence across five continents: defining priorities to reduce cancer disparities in different geographic regions of the world
    • Kamangar F, Dores GM, Anderson WF. Patterns of cancer incidence, mortality, and prevalence across five continents: defining priorities to reduce cancer disparities in different geographic regions of the world. J Clin Oncol. 2006; 24: 2137-2150.
    • (2006) J Clin Oncol , vol.24 , pp. 2137-2150
    • Kamangar, F.1    Dores, G.M.2    Anderson, W.F.3
  • 3
    • 0018568041 scopus 로고
    • cis-Dichlorodiammineplatinum (11)-based chemotherapy as initial treatment in advanced head and neck cancer
    • Wittes R, Heller K, Randolp V, Howard J, Vallejo A, Farr H, et al. cis-Dichlorodiammineplatinum (11)-based chemotherapy as initial treatment in advanced head and neck cancer. Cancer Treat Rep. 1979; 63: 1533-1538.
    • (1979) Cancer Treat Rep , vol.63 , pp. 1533-1538
    • Wittes, R.1    Heller, K.2    Randolp, V.3    Howard, J.4    Vallejo, A.5    Farr, H.6
  • 4
    • 0025741101 scopus 로고
    • Chemotherapy for recurrent and metastatic head and neck cancer
    • Pinto HA, Jacobs C. Chemotherapy for recurrent and metastatic head and neck cancer. Hematol Oncol Clin North Am. 1991; 5: 667-668.
    • (1991) Hematol Oncol Clin North Am , vol.5 , pp. 667-668
    • Pinto, H.A.1    Jacobs, C.2
  • 5
    • 0028157118 scopus 로고
    • A review of neoadjuvant chemotherapy for head and neck cancer: partially shrunken tumors may be both leaner and meaner
    • Rosenthal DI, Pistenmaa DA, Glatstein E. A review of neoadjuvant chemotherapy for head and neck cancer: partially shrunken tumors may be both leaner and meaner. Int J Radiat Oncol Biol Phys. 1994; 28: 315-320.
    • (1994) Int J Radiat Oncol Biol Phys , vol.28 , pp. 315-320
    • Rosenthal, D.I.1    Pistenmaa, D.A.2    Glatstein, E.3
  • 6
    • 0008280176 scopus 로고
    • Induction chemotherapy: promises and limitations
    • J. T. Johnson and M. S. Didolkar (Eds.), Amsterdam/London: Excerpta Medica
    • Vokes E, Haraf D, Weichselbaum R, Brachman D. Induction chemotherapy: promises and limitations. In Head and neck cancer (eds) Johnson JT, Didolkar MS), Amsterdam/London, Excerpta Medica; 1993; pp. 321-326.
    • (1993) Head and Neck Cancer , pp. 321-326
    • Vokes, E.1    Haraf, D.2    Weichselbaum, R.3    Brachman, D.4
  • 8
    • 0025807080 scopus 로고
    • The Department of Veterans Affairs Laryngeal Cancer Study Group
    • Induction chemotherapy plus radiation compared with surgery plus radiation in patients with advanced laryngeal cancer
    • Induction chemotherapy plus radiation compared with surgery plus radiation in patients with advanced laryngeal cancer. The Department of Veterans Affairs Laryngeal Cancer Study Group. N Engl J Med. 1991; 324: 1685-1690.
    • (1991) N Engl J Med , vol.324 , pp. 1685-1690
  • 9
    • 42249104192 scopus 로고    scopus 로고
    • Is laryngeal preservation (LP) with induction chemotherapy (ICT) safe in the treatment of hypopharyngeal SCC? Final results of the phase III EORTC 24891 trial
    • Lefebvre JL, Chevalier D, Luboinski B, Traissac L, Andry G, De Raucourt D, et al. Is laryngeal preservation (LP) with induction chemotherapy (ICT) safe in the treatment of hypopharyngeal SCC? Final results of the phase III EORTC 24891 trial. J Clin Oncol. 2004; 22: 5531.
    • (2004) J Clin Oncol , vol.22 , pp. 5531
    • Lefebvre, J.L.1    Chevalier, D.2    Luboinski, B.3    Traissac, L.4    Andry, G.5    de Raucourt, D.6
  • 10
    • 0345714860 scopus 로고    scopus 로고
    • Concurrent chemotherapy and radiotherapy for organ preservation in advanced laryngeal cancer
    • Forastiere AA, Goepfert H, Maor M, Pajak TF, Weber R, Morrison W, et al. Concurrent chemotherapy and radiotherapy for organ preservation in advanced laryngeal cancer. N Engl J Med. 2003; 349: 2091-2098.
    • (2003) N Engl J Med , vol.349 , pp. 2091-2098
    • Forastiere, A.A.1    Goepfert, H.2    Maor, M.3    Pajak, T.F.4    Weber, R.5    Morrison, W.6
  • 11
    • 0027982841 scopus 로고
    • Phase III trial of initial chemotherapy in stage III or IV head and neck cancers: a study by the Gruppo di Studio sui Tumori della Testa e del Collo
    • Paccagnella A, Orlando A, Marchiori C, Zorat PL, Cavaniglia G, Silieni VC, et al. Phase III trial of initial chemotherapy in stage III or IV head and neck cancers: a study by the Gruppo di Studio sui Tumori della Testa e del Collo. J Natl Cancer Inst. 1994; 86: 265-272.
    • (1994) J Natl Cancer Inst , vol.86 , pp. 265-272
    • Paccagnella, A.1    Orlando, A.2    Marchiori, C.3    Zorat, P.L.4    Cavaniglia, G.5    Silieni, V.C.6
  • 12
    • 9744257104 scopus 로고    scopus 로고
    • Randomized phase III trial of neoadjuvant chemotherapy in head and neck cancer: 10-year follow-up
    • Zorat PL, Pacagnella A, Cavaniglia G, Loreggian L, Gava A, Mione CA, et al. Randomized phase III trial of neoadjuvant chemotherapy in head and neck cancer: 10-year follow-up. J Natl Cancer Inst 2004; 96: 1714-1717.
    • (2004) J Natl Cancer Inst , vol.96 , pp. 1714-1717
    • Zorat, P.L.1    Pacagnella, A.2    Cavaniglia, G.3    Loreggian, L.4    Gava, A.5    Mione, C.A.6
  • 13
    • 17744364263 scopus 로고    scopus 로고
    • Randomized trial of neoadjuvant chemotherapy in oropharyngeal carcinoma
    • Domenge C, Hill C, Lefebvre JL, De Raucourt D, Rhein B, Wibault P, et al. Randomized trial of neoadjuvant chemotherapy in oropharyngeal carcinoma. French Groupe d'Etude des Tumeurs de la Tête et du Cou (GETTEC). Br J Cancer. 2000; 83: 1594-1598.
    • (2000) Br J Cancer , vol.83 , pp. 1594-1598
    • Domenge, C.1    Hill, C.2    Lefebvre, J.L.3    de Raucourt, D.4    Rhein, B.5    Wibault, P.6
  • 16
    • 63649105303 scopus 로고    scopus 로고
    • Randomized trial of induction chemotherapy with cisplatin and 5-fluorouracil with or without docetaxel for larynx preservation
    • Pointreau, Garaud P, Chapet S, Sire C, Tuchais C, Tortochaux J, Faivre S, et al. Randomized trial of induction chemotherapy with cisplatin and 5-fluorouracil with or without docetaxel for larynx preservation. J Natl Cancer Inst. 2009; 101: 498-506.
    • (2009) J Natl Cancer Inst , vol.101 , pp. 498-506
    • Pointreau1    Garaud, P.2    Chapet, S.3    Sire, C.4    Tuchais, C.5    Tortochaux, J.6    Faivre, S.7
  • 17
    • 0034600339 scopus 로고    scopus 로고
    • Evidence for a causal association between human papillomavirus and a subset of head and neck cancers
    • Gillison ML, Koch WM, Capone RB, Spafford M, Westra WH, Wu L, et al. Evidence for a causal association between human papillomavirus and a subset of head and neck cancers. J Natl Cancer Inst. 2000; 92: 709-720.
    • (2000) J Natl Cancer Inst , vol.92 , pp. 709-720
    • Gillison, M.L.1    Koch, W.M.2    Capone, R.B.3    Spafford, M.4    Westra, W.H.5    Wu, L.6
  • 20
    • 0035880630 scopus 로고    scopus 로고
    • Human papillomavirus positive quamous cell carcinoma of the oropharynx: a radiosensitive subgroup of head and neck carcinoma
    • Lindel K, Beer KT, Laissue J, Greiner RH, Aebersold DM. Human papillomavirus positive quamous cell carcinoma of the oropharynx: a radiosensitive subgroup of head and neck carcinoma. Cancer. 2001; 92: 805-813.
    • (2001) Cancer , vol.92 , pp. 805-813
    • Lindel, K.1    Beer, K.T.2    Laissue, J.3    Greiner, R.H.4    Aebersold, D.M.5
  • 21
    • 39649109915 scopus 로고    scopus 로고
    • Improved survival of patients with human papillomavirus-positive head and neck squamous cell carcinoma in a prospective clinical trial
    • Fakhry C, Westra WH, Li S, Cmelak A, Ridge JA, Pinto H, et al. Improved survival of patients with human papillomavirus-positive head and neck squamous cell carcinoma in a prospective clinical trial. J Natl Cancer Inst. 2008; 100: 261-269.
    • (2008) J Natl Cancer Inst , vol.100 , pp. 261-269
    • Fakhry, C.1    Westra, W.H.2    Li, S.3    Cmelak, A.4    Ridge, J.A.5    Pinto, H.6
  • 22
    • 34147140250 scopus 로고    scopus 로고
    • Induction chemotherapy (CT) with weekly pa clitaxel, carboplatin, and cetuximab for squamous cell carcinoma of the head and neck (HN)
    • Kies MS, Garden AS, Holsinger C, Papadimitrakopoulou V, El-Naggar AK, Gillaspy K, et al. Induction chemotherapy (CT) with weekly pa clitaxel, carboplatin, and cetuximab for squamous cell carcinoma of the head and neck (HN). J Clin Oncol. 2006; 24: 5520.
    • (2006) J Clin Oncol , vol.24 , pp. 5520
    • Kies, M.S.1    Garden, A.S.2    Holsinger, C.3    Papadimitrakopoulou, V.4    El-Naggar, A.K.5    Gillaspy, K.6
  • 23
    • 38149123171 scopus 로고    scopus 로고
    • Phase II evaluation of cetuximab (C225) combined with induction paclitaxel and carboplatin followed by C225, paclitaxel, carboplatin, and radiation for stage III/IV operable squamous cancer of the head and neck (ECOG, E2303)
    • Wanebo HJ, Ghebremichael M, Burtness B, Spencer S, Ridge J, Forastiere A, et al. Phase II evaluation of cetuximab (C225) combined with induction paclitaxel and carboplatin followed by C225, paclitaxel, carboplatin, and radiation for stage III/IV operable squamous cancer of the head and neck (ECOG, E2303). J Clin Oncol. 2007; 25: 6015.
    • (2007) J Clin Oncol , vol.25 , pp. 6015
    • Wanebo, H.J.1    Ghebremichael, M.2    Burtness, B.3    Spencer, S.4    Ridge, J.5    Forastiere, A.6
  • 24
    • 57349139886 scopus 로고    scopus 로고
    • Phase II trial of neoadjuvant docetaxel (T), cisplatin (P), and cetuximab (E) followed by concurrent radiation (X), P, and E in locally advanced head and neck cancer (HNC)
    • Argiris E, Gibson MK, Heron DE, Smith RP, Ferris RL, Lai SY, et al. Phase II trial of neoadjuvant docetaxel (T), cisplatin (P), and cetuximab (E) followed by concurrent radiation (X), P, and E in locally advanced head and neck cancer (HNC). J Clin Oncol 2008; 26: 6002.
    • (2008) J Clin Oncol , vol.26 , pp. 6002
    • Argiris, E.1    Gibson, M.K.2    Heron, D.E.3    Smith, R.P.4    Ferris, R.L.5    Lai, S.Y.6
  • 25
    • 0036533894 scopus 로고    scopus 로고
    • Excellent disease control and survival in patients with advanced nasopharyngeal cancer treated with chemoradiation
    • Rischin D, Corry J, Smith J, Stewart J, Hughes P, Peters L. Excellent disease control and survival in patients with advanced nasopharyngeal cancer treated with chemoradiation. J Clin Oncol. 2002; 20: 1845-1852.
    • (2002) J Clin Oncol , vol.20 , pp. 1845-1852
    • Rischin, D.1    Corry, J.2    Smith, J.3    Stewart, J.4    Hughes, P.5    Peters, L.6
  • 26
    • 4143110422 scopus 로고    scopus 로고
    • Phase II study of neoadjuvant carboplatin and paclitaxel followed by radiotherapy and concurrent cisplatin in patients with locoregionally advanced nasopharyngeal carcinoma: therapeutic monitoring with plasma Epstein-Barr virus DNA
    • Chan AT, Ma BB, Lo YM, Leung SF, Kwan WH, Hui EP, et al. Phase II study of neoadjuvant carboplatin and paclitaxel followed by radiotherapy and concurrent cisplatin in patients with locoregionally advanced nasopharyngeal carcinoma: therapeutic monitoring with plasma Epstein-Barr virus DNA. J Clin Oncol. 2004; 22: 3053-3060.
    • (2004) J Clin Oncol , vol.22 , pp. 3053-3060
    • Chan, A.T.1    Ma, B.B.2    Lo, Y.M.3    Leung, S.F.4    Kwan, W.H.5    Hui, E.P.6
  • 27
    • 0034034509 scopus 로고    scopus 로고
    • Hyperfractionated radiation therapy with or without concurrent low-dose daily cisplatin in locally advanced squamous cell carcinoma of the head and neck: a prospective randomized trial
    • Jeremic B, Shibamoto Y, Milicic B, Nikolic N, Dagovic A, Aleksandrovic J, et al. Hyperfractionated radiation therapy with or without concurrent low-dose daily cisplatin in locally advanced squamous cell carcinoma of the head and neck: a prospective randomized trial. J Clin Oncol. 2000; 18: 1458-1464.
    • (2000) J Clin Oncol , vol.18 , pp. 1458-1464
    • Jeremic, B.1    Shibamoto, Y.2    Milicic, B.3    Nikolic, N.4    Dagovic, A.5    Aleksandrovic, J.6
  • 28
    • 16544374983 scopus 로고    scopus 로고
    • Concomitant cisplatin significantly improves locoregional control in advanced head and neck cancers treated with hyperfractionated radiotherapy
    • Huguenin P, Beer KT, Allal A, Rufibach K, Friedli C, Davis JB, et al. Concomitant cisplatin significantly improves locoregional control in advanced head and neck cancers treated with hyperfractionated radiotherapy. J Clin Oncol. 2004; 22: 4665-4673.
    • (2004) J Clin Oncol , vol.22 , pp. 4665-4673
    • Huguenin, P.1    Beer, K.T.2    Allal, A.3    Rufibach, K.4    Friedli, C.5    Davis, J.B.6
  • 29
    • 0037208591 scopus 로고    scopus 로고
    • An intergroup phase III comparison of standard radiation therapy and two schedules of concurrent chemoradiotherapy in patients with unresectable squamous cell head and neck cancer
    • Adelstein D J, Li Y, Adams GL, Wagner Jr H, Kish JA, Ensley JF, et al. An intergroup phase III comparison of standard radiation therapy and two schedules of concurrent chemoradiotherapy in patients with unresectable squamous cell head and neck cancer. J Clin Oncol. 2003; 21: 92-98.
    • (2003) J Clin Oncol , vol.21 , pp. 92-98
    • Adelstein, D.J.1    Li, Y.2    Adams, G.L.3    Wagner Jr., H.4    Kish, J.A.5    Ensley, J.F.6
  • 30
    • 33847344521 scopus 로고    scopus 로고
    • Long-term results of intergroup RTOG 91-11: A phase III trial to preserve the larynx-induction cisplatin/5-FU and radiation therapy
    • Forastiere AA, Maor M, Weber RS, Pajak T, Glisson B, Trotti A, et al. Long-term results of intergroup RTOG 91-11: A phase III trial to preserve the larynx-induction cisplatin/5-FU and radiation therapy. J Clin Oncol. 2006; 24: 5517.
    • (2006) J Clin Oncol , vol.24 , pp. 5517
    • Forastiere, A.A.1    Maor, M.2    Weber, R.S.3    Pajak, T.4    Glisson, B.5    Trotti, A.6
  • 31
  • 32
    • 0032543663 scopus 로고    scopus 로고
    • Hyperfractionated irradiation with or without concurrent chemotherapy for locally advanced head and neck cancer
    • Brizel DM, Albers ME, Fisher SR, Scher RL, Richtsmeier WJ, Hars V, et al. Hyperfractionated irradiation with or without concurrent chemotherapy for locally advanced head and neck cancer. N Engl J Med. 1998; 338: 1798-1804.
    • (1998) N Engl J Med , vol.338 , pp. 1798-1804
    • Brizel, D.M.1    Albers, M.E.2    Fisher, S.R.3    Scher, R.L.4    Richtsmeier, W.J.5    Hars, V.6
  • 33
    • 0033811339 scopus 로고    scopus 로고
    • Stage III and IV cancers of the oropharynx: results of a randomized study of Gortec comparing radiotherapy alone with concomitant chemotherapy
    • Calais G, Alfonsi M, Bardet E, Sire C, Germain T, Bergerot P, et al. Stage III and IV cancers of the oropharynx: results of a randomized study of Gortec comparing radiotherapy alone with concomitant chemotherapy. Bull Cancer. 2000; 87: 48-53.
    • (2000) Bull Cancer , vol.87 , pp. 48-53
    • Calais, G.1    Alfonsi, M.2    Bardet, E.3    Sire, C.4    Germain, T.5    Bergerot, P.6
  • 34
    • 0035424059 scopus 로고    scopus 로고
    • Intensified hyperfractionated accelerated radiotherapy limits the additional benefit of simultaneous chemotherapy - results of a multicentric randomized German trial in advanced head-andneck cancer
    • Starr S, Rudat V, Stuetzer H, Dietz A, Volling P, Schroeder M, et al. Intensified hyperfractionated accelerated radiotherapy limits the additional benefit of simultaneous chemotherapy - results of a multicentric randomized German trial in advanced head-andneck cancer. Int J Radiat Oncol Biol Phys. 2001; 50: 1161-1171.
    • (2001) Int J Radiat Oncol Biol Phys , vol.50 , pp. 1161-1171
    • Starr, S.1    Rudat, V.2    Stuetzer, H.3    Dietz, A.4    Volling, P.5    Schroeder, M.6
  • 35
    • 3042701812 scopus 로고    scopus 로고
    • Final results of the 94-01 French Head and Neck Oncology and Radiotherapy Group randomized trial comparing radiotherapy alone with concomitant radiochemotherapy in advanced-stage oropharynx carcinoma
    • Denis F, Garaud P, Bardet E, Alfonsi M, Sire C, Germain T, et al. Final results of the 94-01 French Head and Neck Oncology and Radiotherapy Group randomized trial comparing radiotherapy alone with concomitant radiochemotherapy in advanced-stage oropharynx carcinoma. J Clin Oncol. 2004; 22: 69-76.
    • (2004) J Clin Oncol , vol.22 , pp. 69-76
    • Denis, F.1    Garaud, P.2    Bardet, E.3    Alfonsi, M.4    Sire, C.5    Germain, T.6
  • 36
    • 0029900724 scopus 로고    scopus 로고
    • Larynx preservation in pyriform sinus cancer: Preliminary results of a European Organization for Research and Treatment of Cancer phase III trial. EORTC Head and Neck Cancer Cooperative Group
    • Lefebvre JL, Chevalier D, Luboinski B, Kirkpatrick A, Collette L., Sahmoud, T. Larynx preservation in pyriform sinus cancer: Preliminary results of a European Organization for Research and Treatment of Cancer phase III trial. EORTC Head and Neck Cancer Cooperative Group. J Natl Cancer Inst. 1996; 88: 890-899.
    • (1996) J Natl Cancer Inst , vol.88 , pp. 890-899
    • Lefebvre, J.L.1    Chevalier, D.2    Luboinski, B.3    Kirkpatrick, A.4    Collette, L.5    Sahmoud, T.6
  • 37
    • 0031947875 scopus 로고    scopus 로고
    • Chemoradiotherapy versus radiotherapy in patients with advanced nasopharyngeal cancer: Phase III randomized Intergroup study 0099
    • Al-Sarraf M, LeBlanc M, Giri PG, Fu KK, Cooper J, Vuong T, et al. Chemoradiotherapy versus radiotherapy in patients with advanced nasopharyngeal cancer: Phase III randomized Intergroup study 0099. J Clin Oncol. 1998; 16: 1310-1317.
    • (1998) J Clin Oncol , vol.16 , pp. 1310-1317
    • Al-Sarraf, M.1    Leblanc, M.2    Giri, P.G.3    Fu, K.K.4    Cooper, J.5    Vuong, T.6
  • 38
    • 0036275317 scopus 로고    scopus 로고
    • Combined chemoradiation versus radiation therapy alone in locally advanced nasopharyngeal carcinoma: Results of a meta-analysis of 1,528 patients from six randomized trials
    • Huncharek M, Kupelnick, B. Combined chemoradiation versus radiation therapy alone in locally advanced nasopharyngeal carcinoma: Results of a meta-analysis of 1, 528 patients from six randomized trials. Am J Clin Oncol 2002; 25: 219-223.
    • (2002) Am J Clin Oncol , vol.25 , pp. 219-223
    • Huncharek, M.1    Kupelnick, B.2
  • 39
    • 29244448683 scopus 로고    scopus 로고
    • Chemotherapy in locally advanced nasopharyngeal carcinoma: an individual patient data meta-analysis of eight randomized trials and 1753 patients
    • Baujat B, Audry H, Bourhis J, Chan AT, Onat H, Chua DT, et al. Chemotherapy in locally advanced nasopharyngeal carcinoma: an individual patient data meta-analysis of eight randomized trials and 1753 patients. Int J Radiat Oncol Biol Phys. 2006; 64: 47-56.
    • (2006) Int J Radiat Oncol Biol Phys , vol.64 , pp. 47-56
    • Baujat, B.1    Audry, H.2    Bourhis, J.3    Chan, A.T.4    Onat, H.5    Chua, D.T.6
  • 40
    • 2342592623 scopus 로고    scopus 로고
    • Postoperative irradiation with or without concomitant chemotherapy for locally advanced head and neck cancer
    • Bernier J, Domenge C, Ozsahin M, Matuszewska K, Lefebvre JL, Greiner RH, et al. Postoperative irradiation with or without concomitant chemotherapy for locally advanced head and neck cancer. N Engl J Med. 2004; 350: 1945-1952.
    • (2004) N Engl J Med , vol.350 , pp. 1945-1952
    • Bernier, J.1    Domenge, C.2    Ozsahin, M.3    Matuszewska, K.4    Lefebvre, J.L.5    Greiner, R.H.6
  • 41
    • 2342517421 scopus 로고    scopus 로고
    • Postoperative concurrent radiotherapy and chemotherapy for highrisk squamous-cell carcinoma of the head and neck
    • Cooper JS, Pajak TF, Forastiere AA, Jacobs J, Campbell BH, Saxman SB, et al. Postoperative concurrent radiotherapy and chemotherapy for highrisk squamous-cell carcinoma of the head and neck. N Engl J Med. 2004; 350: 1937-1944.
    • (2004) N Engl J Med , vol.350 , pp. 1937-1944
    • Cooper, J.S.1    Pajak, T.F.2    Forastiere, A.A.3    Jacobs, J.4    Campbell, B.H.5    Saxman, S.B.6
  • 42
    • 34848920999 scopus 로고    scopus 로고
    • Long-term survival results of a phase III intergroup trial (RTOG 95-01) of surgery followed by radiotherapy vs. radiochemotherapy for resectable high risk squamous cell carcinoma of the Head and Neck
    • Cooper JS, Pajak TF, Forastiere A, Jacobs J, Campbell BH, Saxman SB, et al. Long-term survival results of a phase III intergroup trial (RTOG 95-01) of surgery followed by radiotherapy vs. radiochemotherapy for resectable high risk squamous cell carcinoma of the Head and Neck. Int J Radiat Oncol Biol Phys 2006; 66: S14-S15.
    • (2006) Int J Radiat Oncol Biol Phys , vol.66
    • Cooper, J.S.1    Pajak, T.F.2    Forastiere, A.3    Jacobs, J.4    Campbell, B.H.5    Saxman, S.B.6
  • 43
    • 25844523780 scopus 로고    scopus 로고
    • Defining risk levels in locally advanced head and neck cancers: A comparative analysis of concurrent postoperative radiation plus chemotherapy trials of the EORTC (#22931) and RTOG (# 9501)
    • Bernier J, Cooper JS, Pajak TF, van Glabbeke M, Bourhis J, Forastiere A, et al. Defining risk levels in locally advanced head and neck cancers: A comparative analysis of concurrent postoperative radiation plus chemotherapy trials of the EORTC (#22931) and RTOG (# 9501). Head Neck. 2005; 27: 843-850.
    • (2005) Head Neck , vol.27 , pp. 843-850
    • Bernier, J.1    Cooper, J.S.2    Pajak, T.F.3    van Glabbeke, M.4    Bourhis, J.5    Forastiere, A.6
  • 44
    • 0034681783 scopus 로고    scopus 로고
    • Chemotherapy added to locoregional treatment for head and neck squamous cell carcinoma: three meta-analyses of updated individual data
    • Pignon JP, Bourhis C, Domenge C, Designe L, on behalf of the MACHNC Collaborative Group. Chemotherapy added to locoregional treatment for head and neck squamous cell carcinoma: three meta-analyses of updated individual data. Lancet. 2000; 355: 949-955.
    • (2000) Lancet , vol.355 , pp. 949-955
    • Pignon, J.P.1    Bourhis, C.2    Domenge, C.3    Designe, L.4
  • 45
    • 66949128922 scopus 로고    scopus 로고
    • Metaanalysis of chemotherapy in head and neck cancer (MACH-NC): An update on 93 radomised trials and 17,346 patients
    • Pignon JP, le Maitre A, Maillard E, Bourhis J on behalf of the MACHNC Collaborative Group. Metaanalysis of chemotherapy in head and neck cancer (MACH-NC): An update on 93 radomised trials and 17, 346 patients. Radiotherapy and Oncology 2009; 92: 4-14.
    • (2009) Radiotherapy and Oncology , vol.92 , pp. 4-14
    • Pignon, J.P.1    le Maitre, A.2    Maillard, E.3
  • 46
    • 53449085820 scopus 로고    scopus 로고
    • Optimizing approaches to head and neck cancer. Metastatic head and neck cancer: New options
    • Licitra, L, Locati, LD, Bossi, P. Optimizing approaches to head and neck cancer. Metastatic head and neck cancer: New options. Ann Oncol. 2008; 19Suppl 7: vii200-vii203.
    • (2008) Ann Oncol , vol.19 , Issue.SUPPL. 7
    • Licitra, L.1    Locati, L.D.2    Bossi, P.3
  • 47
    • 0023368738 scopus 로고
    • Platinum analogs in recurrent and advanced head and neck cancer: a Southwest Oncology Group and Wayne State University Study
    • Al-Sarraf M, Metch B, Kish J, Ensley J, Rinehart JJ, Schuller DE, et al. Platinum analogs in recurrent and advanced head and neck cancer: a Southwest Oncology Group and Wayne State University Study. Cancer Treat Rep 1987; 71: 723-726.
    • (1987) Cancer Treat Rep , vol.71 , pp. 723-726
    • Al-Sarraf, M.1    Metch, B.2    Kish, J.3    Ensley, J.4    Rinehart, J.J.5    Schuller, D.E.6
  • 48
    • 0020640276 scopus 로고
    • A prospective randomized trial of methotrexate versus cisplatin in the treatment of recurrent squamous cell carcinoma of the head and neck
    • Hong WK, Schaefer S, Issell B, Cummings C, Luedke D, Bromer R, et al. A prospective randomized trial of methotrexate versus cisplatin in the treatment of recurrent squamous cell carcinoma of the head and neck. Cancer. 1983; 52: 206-210.
    • (1983) Cancer , vol.52 , pp. 206-210
    • Hong, W.K.1    Schaefer, S.2    Issell, B.3    Cummings, C.4    Luedke, D.5    Bromer, R.6
  • 49
    • 0026569931 scopus 로고
    • A phase III randomized study comparing cisplatin and fluorouracil as single agents and in combination for advanced squamous cell carcinoma of the head and neck
    • Jacobs C, Lyman G, Velez-Garcia E, Sridhar KS, Knight W, Hochster H, et al. A phase III randomized study comparing cisplatin and fluorouracil as single agents and in combination for advanced squamous cell carcinoma of the head and neck. J Clin Oncol. 1992; 10: 257-263.
    • (1992) J Clin Oncol , vol.10 , pp. 257-263
    • Jacobs, C.1    Lyman, G.2    Velez-Garcia, E.3    Sridhar, K.S.4    Knight, W.5    Hochster, H.6
  • 50
    • 4444363098 scopus 로고    scopus 로고
    • Results of a randomised phase II study comparing docetaxel with methotrexate in patients with recurrent head and neck cancer
    • Guardiola E, Peyrade, F, Chaigneau, L, Cupissol D, Tchiknavorian X, Bompas E, et al. Results of a randomised phase II study comparing docetaxel with methotrexate in patients with recurrent head and neck cancer. Eur J Cancer. 2004; 40: 2071-2076.
    • (2004) Eur J Cancer , vol.40 , pp. 2071-2076
    • Guardiola, E.1    Peyrade, F.2    Chaigneau, L.3    Cupissol, D.4    Tchiknavorian, X.5    Bompas, E.6
  • 51
    • 34548369637 scopus 로고    scopus 로고
    • Single-agent docetaxel in patients with platinumrefractory metastatic or recurrent squamous cell carcinoma of the head and neck (SCCHN)
    • Zenda S, Onozawa Y, Boku N, Ebihara M, Onitsuka T. Single-agent docetaxel in patients with platinumrefractory metastatic or recurrent squamous cell carcinoma of the head and neck (SCCHN). Jpn J Clin Oncol 2007; 37: 477-481.
    • (2007) Jpn J Clin Oncol , vol.37 , pp. 477-481
    • Zenda, S.1    Onozawa, Y.2    Boku, N.3    Ebihara, M.4    Onitsuka, T.5
  • 52
    • 0032102421 scopus 로고    scopus 로고
    • Final report of a phase II evaluation of paclitaxel in patients with advanced squamous cell carcinoma of the head and neck: An Eastern Cooperative Oncology Group Trial (PA390)
    • Forastiere AA, Shank D, Neuberg D, Taylor SG, DeConti RC, Adams G. Final report of a phase II evaluation of paclitaxel in patients with advanced squamous cell carcinoma of the head and neck: An Eastern Cooperative Oncology Group Trial (PA390). Cancer. 1998; 82: 2270-2274.
    • (1998) Cancer , vol.82 , pp. 2270-2274
    • Forastiere, A.A.1    Shank, D.2    Neuberg, D.3    Taylor, S.G.4    Deconti, R.C.5    Adams, G.6
  • 53
    • 0028241688 scopus 로고
    • A phase II study of Gemcitabine (LY 188011) in patients with advanced squamous cell carcinoma of the head and neck. EORTC Early Clinical Trials Group
    • Catimel G, Vermorken JB, Clavel M, de Mulder P, Judson I, Sessa C, et al. A phase II study of Gemcitabine (LY 188011) in patients with advanced squamous cell carcinoma of the head and neck. EORTC Early Clinical Trials Group. Ann Oncol. 1994; 5: 543-547.
    • (1994) Ann Oncol , vol.5 , pp. 543-547
    • Catimel, G.1    Vermorken, J.B.2    Clavel, M.3    de Mulder, P.4    Judson, I.5    Sessa, C.6
  • 54
    • 12744272174 scopus 로고    scopus 로고
    • Topoisomerases in the treatment of metastatic or recurrent squamous carcinoma of the head and neck
    • Murphy BA. Topoisomerases in the treatment of metastatic or recurrent squamous carcinoma of the head and neck. Expert Opin Pharmacother. 2005; 6: 85-92.
    • (2005) Expert Opin Pharmacother , vol.6 , pp. 85-92
    • Murphy, B.A.1
  • 55
    • 0035446433 scopus 로고    scopus 로고
    • Pemetrexed disodium in recurrent locally advanced or metastatic squamous cell carcinoma of the head and neck
    • Pivot X, Raymond E, Laguerre B, Degardin M, Cals L, Armand JP, et al. Pemetrexed disodium in recurrent locally advanced or metastatic squamous cell carcinoma of the head and neck. Br J Cancer. 2001; 85: 649-655.
    • (2001) Br J Cancer , vol.85 , pp. 649-655
    • Pivot, X.1    Raymond, E.2    Laguerre, B.3    Degardin, M.4    Cals, L.5    Armand, J.P.6
  • 56
    • 55849139425 scopus 로고    scopus 로고
    • Molecularly targeted agents in the treatment of recurrent or metastatic squamous cell carcinomas of the head and neck
    • Le Tourneau C, Chen EX. Molecularly targeted agents in the treatment of recurrent or metastatic squamous cell carcinomas of the head and neck. Hematol Oncol Clin North Am. 2008; 22: 1209-1220.
    • (2008) Hematol Oncol Clin North Am , vol.22 , pp. 1209-1220
    • Le Tourneau, C.1    Chen, E.X.2
  • 57
    • 0037674062 scopus 로고
    • Phase II trial of ZD1839 in recurrent or metastatic squamous cell carcinoma of the head and neck
    • Cohen EE, Rosen F, Stadler WM, Recant W, Stenson K, Huo D, et al. Phase II trial of ZD1839 in recurrent or metastatic squamous cell carcinoma of the head and neck. J Clin Oncol. 1987; 21: 1980-1987.
    • (1987) J Clin Oncol , vol.21 , pp. 1980-1987
    • Cohen, E.E.1    Rosen, F.2    Stadler, W.M.3    Recant, W.4    Stenson, K.5    Huo, D.6
  • 58
    • 1842772526 scopus 로고    scopus 로고
    • Multicenter phase II study of erlotinib, an oral epidermal growth factor receptor tyrosine kinase inhibitor, in patients with recurrent or metastatic squamous cell cancer of the head and neck
    • Soulieres D, Senzer NN, Vokes EE, Hidalgo M, Agarwala SS, Siu LL. Multicenter phase II study of erlotinib, an oral epidermal growth factor receptor tyrosine kinase inhibitor, in patients with recurrent or metastatic squamous cell cancer of the head and neck. J Clin Oncol. 2004; 22: 77-85.
    • (2004) J Clin Oncol , vol.22 , pp. 77-85
    • Soulieres, D.1    Senzer, N.N.2    Vokes, E.E.3    Hidalgo, M.4    Agarwala, S.S.5    Siu, L.L.6
  • 59
    • 0026645077 scopus 로고
    • Randomized comparison of cisplatin plus fluorouracil and carboplatin plus fluorouracil versus methotrexate in advanced squamouscell carcinoma of the head and neck: a Southwest Oncology Group study
    • Forastiere AA, Metch B, Schuller DE, Ensley JF, Hutchins LF, Triozzi P, et al. Randomized comparison of cisplatin plus fluorouracil and carboplatin plus fluorouracil versus methotrexate in advanced squamouscell carcinoma of the head and neck: a Southwest Oncology Group study. J Clin Oncol. 1992; 10: 1245-1251.
    • (1992) J Clin Oncol , vol.10 , pp. 1245-1251
    • Forastiere, A.A.1    Metch, B.2    Schuller, D.E.3    Ensley, J.F.4    Hutchins, L.F.5    Triozzi, P.6
  • 60
    • 0026569931 scopus 로고
    • A phase III randomized study comparing cisplatin and fluorouracil as single agents and in combination for advanced squamous cell carcinoma of the head and neck
    • Jacobs C, Lyman G, Velez-Garcia E, Sridhar KS, Knight W, Hochster H, et al. A phase III randomized study comparing cisplatin and fluorouracil as single agents and in combination for advanced squamous cell carcinoma of the head and neck. J Clin Oncol. 1992; 10: 257-263.
    • (1992) J Clin Oncol , vol.10 , pp. 257-263
    • Jacobs, C.1    Lyman, G.2    Velez-Garcia, E.3    Sridhar, K.S.4    Knight, W.5    Hochster, H.6
  • 61
    • 20644452264 scopus 로고    scopus 로고
    • Randomized phase III evaluation of cisplatin plus fluorouracil versus cisplatin plus paclitaxel in advanced head and neck cancer (E1395): an intergroup trial of the Eastern Cooperative Oncology Group
    • Gibson MK, Li Y, Murphy B, Hussain MHA, DeConti RC, Ensley J, et al. Randomized phase III evaluation of cisplatin plus fluorouracil versus cisplatin plus paclitaxel in advanced head and neck cancer (E1395): an intergroup trial of the Eastern Cooperative Oncology Group. J Clin Oncol. 2005; 23: 3562-3567.
    • (2005) J Clin Oncol , vol.23 , pp. 3562-3567
    • Gibson, M.K.1    Li, Y.2    Murphy, B.3    Hussain, M.H.A.4    Deconti, R.C.5    Ensley, J.6
  • 62
    • 0037087537 scopus 로고    scopus 로고
    • Phase II trial of docetaxel and cisplatin combination chemotherapy in patients with squamous cell carcinoma of the head and neck
    • Glisson BS, Murphy BA, Frenette G, Khuri FR, Forastiere AA. Phase II trial of docetaxel and cisplatin combination chemotherapy in patients with squamous cell carcinoma of the head and neck. J Clin Oncol. 2002; 20: 1593-1599.
    • (2002) J Clin Oncol , vol.20 , pp. 1593-1599
    • Glisson, B.S.1    Murphy, B.A.2    Frenette, G.3    Khuri, F.R.4    Forastiere, A.A.5
  • 63
    • 0032960189 scopus 로고    scopus 로고
    • Paclitaxel and gemcitabine in advanced non-nasopharyngeal head and neck cancer: a phase II study conducted by the Hellenic Cooperative Oncology Group
    • Fountzilas G, Stathopoulos G, Nicolaides C, Kalogera-Fountzila A, Kalofonos H, Nikolaou A, et al. Paclitaxel and gemcitabine in advanced non-nasopharyngeal head and neck cancer: a phase II study conducted by the Hellenic Cooperative Oncology Group. Ann Oncol. 1999; 10: 475-478.
    • (1999) Ann Oncol , vol.10 , pp. 475-478
    • Fountzilas, G.1    Stathopoulos, G.2    Nicolaides, C.3    Kalogera-Fountzila, A.4    Kalofonos, H.5    Nikolaou, A.6
  • 64
    • 34250005439 scopus 로고    scopus 로고
    • Docetaxel plus gemcitabine in recurrent and/or metastatic squamous cell carcinoma of the head and neck: a phase II multicenter study
    • Labourey JL, Cupissol D, Calais G, Tourani JM, Kohser F, Borel C, et al. Docetaxel plus gemcitabine in recurrent and/or metastatic squamous cell carcinoma of the head and neck: a phase II multicenter study. Am J Clin Oncol. 2007; 30: 278-282.
    • (2007) Am J Clin Oncol , vol.30 , pp. 278-282
    • Labourey, J.L.1    Cupissol, D.2    Calais, G.3    Tourani, J.M.4    Kohser, F.5    Borel, C.6
  • 65
    • 0032441793 scopus 로고    scopus 로고
    • Phase II trial of cisplatin and gemcitabine in advanced squamous-cell carcinoma of the head and neck
    • Hitt R, Castellano D, Hidalgo M, Garcia-Carbonero R, Pena M, Brandariz A, et al. Phase II trial of cisplatin and gemcitabine in advanced squamous-cell carcinoma of the head and neck. Ann Oncol. 1998; 9: 1347-1349.
    • (1998) Ann Oncol , vol.9 , pp. 1347-1349
    • Hitt, R.1    Castellano, D.2    Hidalgo, M.3    Garcia-Carbonero, R.4    Pena, M.5    Brandariz, A.6
  • 66
    • 5644253024 scopus 로고    scopus 로고
    • Docetaxel plus 5-fluorouracil in locally recurrent and/or metastatic squamous cell carcinoma of the head and neck: A phase II multicenter study
    • Genet D, Cupissol D, Calais G, Bontemps P, Bourgeois H, Dutin JP, et al. Docetaxel plus 5-fluorouracil in locally recurrent and/or metastatic squamous cell carcinoma of the head and neck: A phase II multicenter study. Am J Clin Oncol. 2004; 27: 472-476.
    • (2004) Am J Clin Oncol , vol.27 , pp. 472-476
    • Genet, D.1    Cupissol, D.2    Calais, G.3    Bontemps, P.4    Bourgeois, H.5    Dutin, J.P.6
  • 67
    • 33845961559 scopus 로고    scopus 로고
    • Phase II analysis of paclitaxel and capecitabine in the treatment of recurrent or disseminated squamous cell carcinoma of the head and neck region
    • Bentzen JD, Hansen HS. Phase II analysis of paclitaxel and capecitabine in the treatment of recurrent or disseminated squamous cell carcinoma of the head and neck region. Head Neck. 2007; 29: 47-51.
    • (2007) Head Neck , vol.29 , pp. 47-51
    • Bentzen, J.D.1    Hansen, H.S.2
  • 68
    • 12344270059 scopus 로고    scopus 로고
    • Phase II trial of cisplatin and capecitabine in patients with squamous cell carcinoma of the head and neck, and correlative study of angiogenic factors
    • Hitt R, Jimeno A, Rodriguez-Pinilla M, Rodriguez-Peralto JL, Millan JM, Lopez-Martin A, et al. Phase II trial of cisplatin and capecitabine in patients with squamous cell carcinoma of the head and neck, and correlative study of angiogenic factors. Br J Cancer. 2004; 91: 2005-2011.
    • (2004) Br J Cancer , vol.91 , pp. 2005-2011
    • Hitt, R.1    Jimeno, A.2    Rodriguez-Pinilla, M.3    Rodriguez-Peralto, J.L.4    Millan, J.M.5    Lopez-Martin, A.6
  • 69
    • 33745873717 scopus 로고    scopus 로고
    • A phase II evaluation of a 3-hour infusion of paclitaxel, cisplatin, and 5-fluorouracil in patients with advanced or recurrent squamous cell carcinoma of the head and neck: Southwest Oncology Group study 0007
    • Worden FP, Moon J, Samlowski W, Clark JI, Dakhil SR, Williamson S, et al. A phase II evaluation of a 3-hour infusion of paclitaxel, cisplatin, and 5-fluorouracil in patients with advanced or recurrent squamous cell carcinoma of the head and neck: Southwest Oncology Group study 0007. Cancer. 2006; 107: 319-327.
    • (2006) Cancer , vol.107 , pp. 319-327
    • Worden, F.P.1    Moon, J.2    Samlowski, W.3    Clark, J.I.4    Dakhil, S.R.5    Williamson, S.6
  • 70
    • 32144459527 scopus 로고    scopus 로고
    • A phase II trial of docetaxel, cisplatin and 5-fluorouracil in patients with recurrent squamous cell carcinoma of the head and neck (SCCHN)
    • Baghi M, Hambek M, Wagenblast J, May A, Gstoettner W, Knecht R. A phase II trial of docetaxel, cisplatin and 5-fluorouracil in patients with recurrent squamous cell carcinoma of the head and neck (SCCHN). Anticancer Res. 2006; 26: 585-590.
    • (2006) Anticancer Res , vol.26 , pp. 585-590
    • Baghi, M.1    Hambek, M.2    Wagenblast, J.3    May, A.4    Gstoettner, W.5    Knecht, R.6
  • 71
    • 0031897977 scopus 로고    scopus 로고
    • Phase II trial of paclitaxel, ifosfamide, and cisplatin in patients with recurrent head and neck squamous cell carcinoma
    • Shin DM, Glisson BS, Khuri FR, Ginsberg L, Papadimitrakopoulou V, Lee JJ, et al. Phase II trial of paclitaxel, ifosfamide, and cisplatin in patients with recurrent head and neck squamous cell carcinoma. J Clin Oncol. 1998; 16: 1325-1330.
    • (1998) J Clin Oncol , vol.16 , pp. 1325-1330
    • Shin, D.M.1    Glisson, B.S.2    Khuri, F.R.3    Ginsberg, L.4    Papadimitrakopoulou, V.5    Lee, J.J.6
  • 72
    • 0028359951 scopus 로고
    • Randomized comparison of cisplatin, methotrexate, bleomycin and vincristine (CABO) versus cisplatin and 5-fluorouracil (CF) versus cisplatin (C) in recurrent or metastatic squamous cell carcinoma of the head and neck. A phase III study of the EORTC Head and Neck Cancer Cooperative Group
    • Clavel M, Vermorken JB, Cognetti F, Cappelaere P, de Mulder PH, Schornagel JH, et al. Randomized comparison of cisplatin, methotrexate, bleomycin and vincristine (CABO) versus cisplatin and 5-fluorouracil (CF) versus cisplatin (C) in recurrent or metastatic squamous cell carcinoma of the head and neck. A phase III study of the EORTC Head and Neck Cancer Cooperative Group. Ann Oncol. 1994; 5: 521-526.
    • (1994) Ann Oncol , vol.5 , pp. 521-526
    • Clavel, M.1    Vermorken, J.B.2    Cognetti, F.3    Cappelaere, P.4    de Mulder, P.H.5    Schornagel, J.H.6
  • 73
    • 34250180582 scopus 로고    scopus 로고
    • Open-label, uncontrolled, multicenter phase II study to evaluate the efficacy and toxicity of cetuximab as a single agent in patients with recurrent and/or metastatic squamous cell carcinoma of the head and neck who failed to respond to platinum-based therapy
    • Vermorken JB, Trigo J, Hitt R, Koralewski P, Diaz-Rubio E, Rolland F, et al. Open-label, uncontrolled, multicenter phase II study to evaluate the efficacy and toxicity of cetuximab as a single agent in patients with recurrent and/or metastatic squamous cell carcinoma of the head and neck who failed to respond to platinum-based therapy. J Clin Oncol. 2007; 25: 2171-2177.
    • (2007) J Clin Oncol , vol.25 , pp. 2171-2177
    • Vermorken, J.B.1    Trigo, J.2    Hitt, R.3    Koralewski, P.4    Diaz-Rubio, E.5    Rolland, F.6
  • 74
    • 24944490558 scopus 로고    scopus 로고
    • Phase II multicenter study of the epidermal growth factor receptor antibody cetuximab and cisplatin for recurrent and refractory squamous cell carcinoma of the head and neck
    • Herbst RS, Arquette M, Shin DM, Dicke K, Vokes EE, Azarnia N, et al. Phase II multicenter study of the epidermal growth factor receptor antibody cetuximab and cisplatin for recurrent and refractory squamous cell carcinoma of the head and neck. J Clin Oncol. 2005; 23: 5578-5587.
    • (2005) J Clin Oncol , vol.23 , pp. 5578-5587
    • Herbst, R.S.1    Arquette, M.2    Shin, D.M.3    Dicke, K.4    Vokes, E.E.5    Azarnia, N.6
  • 75
    • 23844523253 scopus 로고    scopus 로고
    • A. Phase II multicenter study of the antiepidermal growth factor receptor monoclonal antibody cetuximab in combination with platinum-based chemotherapy in patients with platinumrefractory metastatic and/or recurrent squamous cell carcinoma of the head and neck
    • Baselga J, Trigo JM, Bourhis J, Tortochaux J, Cortes-Funes H, Hitt R, et al. A. Phase II multicenter study of the antiepidermal growth factor receptor monoclonal antibody cetuximab in combination with platinum-based chemotherapy in patients with platinumrefractory metastatic and/or recurrent squamous cell carcinoma of the head and neck. J Clin Oncol. 2005; 23: 5568-5577.
    • (2005) J Clin Oncol , vol.23 , pp. 5568-5577
    • Baselga, J.1    Trigo, J.M.2    Bourhis, J.3    Tortochaux, J.4    Cortes-Funes, H.5    Hitt, R.6
  • 76
    • 33144461661 scopus 로고    scopus 로고
    • Phase III randomized trial of cisplatin plus placebo compared with cisplatin plus cetuximab in metastatic/recurrent head and neck cancer: An Eastern Cooperative Oncology Group study
    • Burtness B, Goldwasser MA, Flood W, Mattar B, Forastiere AA. Phase III randomized trial of cisplatin plus placebo compared with cisplatin plus cetuximab in metastatic/recurrent head and neck cancer: An Eastern Cooperative Oncology Group study. J Clin Oncol. 2005; 23: 8646-8654.
    • (2005) J Clin Oncol , vol.23 , pp. 8646-8654
    • Burtness, B.1    Goldwasser, M.A.2    Flood, W.3    Mattar, B.4    Forastiere, A.A.5
  • 78
    • 62349097073 scopus 로고    scopus 로고
    • A phase I study of erlotinib and bevacizumab for recurrent or metastatic squamous cell carcinoma of the head and neck (HNC)
    • Cohen EE, Karrison TG, Wong SJ, Skoog-Sluman LJ, Kosloff MF, Dancey J, et al. A phase I study of erlotinib and bevacizumab for recurrent or metastatic squamous cell carcinoma of the head and neck (HNC). Lancet Oncol. 2009; 10: 247-257.
    • (2009) Lancet Oncol , vol.10 , pp. 247-257
    • Cohen, E.E.1    Karrison, T.G.2    Wong, S.J.3    Skoog-Sluman, L.J.4    Kosloff, M.F.5    Dancey, J.6
  • 79
    • 33748643451 scopus 로고    scopus 로고
    • A phase I study of bevacizumab (B) with fluorouracil (F) and hydroxyurea (H) with concomitant radiotherapy (X) (B-FHX) for poor prognosis head and neck cancer (HNC)
    • Seiwert TY, Haraf DJ, Cohen EE, Stenson K, Mauer AM, Dekker A, et al. A phase I study of bevacizumab (B) with fluorouracil (F) and hydroxyurea (H) with concomitant radiotherapy (X) (B-FHX) for poor prognosis head and neck cancer (HNC). Proc Am Soc Clin Oncol. 2006; 24: 5530.
    • (2006) Proc Am Soc Clin Oncol. , vol.24 , pp. 5530
    • Seiwert, T.Y.1    Haraf, D.J.2    Cohen, E.E.3    Stenson, K.4    Mauer, A.M.5    Dekker, A.6


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