Atorvastatin therapy reduces serum uric acid levels: A meta-analysis of randomized controlled trials

International Journal of Cardiology

Volumn 157, Issue 2, 2012, Pages 255-257

  Takagi, Hisato ^a   Umemoto, Takuya ^a  

^a SHIZUOKA MEDICAL CENTER   (Japan)

Author keywords

Atorvastatin; Meta analysis; Randomized controlled trial; Uric acid

Indexed keywords

ATORVASTATIN; CREATININE; FENOFIBRATE; SODIUM; URIC ACID;

CREATININE BLOOD LEVEL; DRUG EFFICACY; DRUG MECHANISM; HUMAN; INSULIN SENSITIVITY; KIDNEY FUNCTION; KIDNEY TUBULE ABSORPTION; LETTER; META ANALYSIS; OUTCOMES RESEARCH; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL (TOPIC); SODIUM URINE LEVEL; URIC ACID BLOOD LEVEL; URIC ACID URINE LEVEL;

EID: 84861101537     PISSN: 01675273     EISSN: 18741754     Source Type: Journal    
DOI: 10.1016/j.ijcard.2012.01.092     Document Type: Article

References (18)

1. S.G. Tsouli, E.N. Liberopoulos, D.P. Mikhailidis, V.G. Athyros, and M.S. Elisaf Elevated serum uric acid levels in metabolic syndrome: an active component or an innocent bystander? Metabolism 55 2006 1293 1301
2. D.H. Kang, T. Nakagawa, and L. Feng A role for uric acid in the progression of renal disease J Am Soc Nephrol 13 2002 2888 2897
3. C. Bickel, H.J. Rupprecht, and S. Blankenberg Serum uric acid as an independent predictor of mortality in patients with angiographically proven coronary artery disease Am J Cardiol 89 2002 12 17
4. J. Fang, and M.H. Alderman Serum uric acid and cardiovascular mortality the NHANES I epidemiologic follow-up study, 1971-1992. National Health and Nutrition Examination Survey JAMA 283 2000 2404 2410
5. A.G. Ioachimescu, D.M. Brennan, B.M. Hoar, S.L. Hazen, and B.J. Hoogwerf Serum uric acid is an independent predictor of all-cause mortality in patients at high risk of cardiovascular disease: a preventive cardiology information system (PreCIS) database cohort study Arthritis Rheum 58 2008 623 630
6. V.G. Athyros, M. Elisaf, and A.A. Papageorgiou Effect of statins versus untreated dyslipidemia on serum uric acid levels in patients with coronary heart disease: a subgroup analysis of the GREek Atorvastatin and Coronary-heart- disease Evaluation (GREACE) study Am J Kidney Dis 43 2004 589 599
7. H.J. Milionis, E. Rizos, and M. Kostapanos Treating to target patients with primary hyperlipidaemia: comparison of the effects of ATOrvastatin and ROSuvastatin (the ATOROS study) Curr Med Res Opin 22 2006 1123 1131
8. K. Saku, B. Zhang, and K. Noda PATROL Trial Investigators. Randomized head-to-head comparison of pitavastatin, atorvastatin, and rosuvastatin for safety and efficacy (quantity and quality of LDL): the PATROL trial Circ J 75 2011 1493 1505
9. V.G. Athyros, A. Karagiannis, and E.S. Ganotakis Association between the changes in renal function and serum uric acid levels during multifactorial intervention and clinical outcome in patients with metabolic syndrome. A post hoc analysis of the ATTEMPT study Curr Med Res Opin 27 2011 1659 1668
10. C.J. Ge, S.Z. Lu, Y.D. Chen, X.F. Wu, S.J. Hu, and Y. Ji Synergistic effect of amlodipine and atorvastatin on blood pressure, left ventricular remodeling, and C-reactive protein in hypertensive patients with primary hypercholesterolemia Heart Vessels 23 2008 91 95
11. H.J. Milionis, A.I. Kakafika, and S.G. Tsouli Effects of statin treatment on uric acid homeostasis in patients with primary hyperlipidemia Am Heart J 148 2004 635 640
12. J. Malik, V. Melenovsky, and D. Wichterle Both fenofibrate and atorvastatin improve vascular reactivity in combined hyperlipidaemia (fenofibrate versus atorvastatin trial-FAT) Cardiovasc Res 52 2001 290 298
13. P. Giral, E. Bruckert, N. Jacob, M.J. Chapman, M.J. Foglietti, and G. Turpin Homocysteine and lipid lowering agents. A comparison between atorvastatin and fenofibrate in patients with mixed hyperlipidemia Atherosclerosis 154 2001 421 427
14. G. Paolisso, M. Barbagallo, and G. Petrella Effects of simvastatin and atorvastatin administration on insulin resistance and respiratory quotient in aged dyslipidemic non-insulin dependent diabetic patients Atherosclerosis 150 2000 121 127
15. G.S. Huggins, R.C. Pasternak, N.M. Alpert, A.J. Fischman, and H. Gewirtz Effects of short-term treatment of hyperlipidemia on coronary vasodilator function and myocardial perfusion in regions having substantial impairment of baseline dilator reverse Circulation 98 1998 1291 1296
16. M.P. O'Donnell, B.L. Kasiske, Y. Kim, P.G. Schmitz, and W.F. Keane Lovastatin retards the progression of established glomerular disease in obese Zucker rats Am J Kidney Dis 22 1993 83 89
17. C. Harvengt, F. Heller, and J.P. Desager Hypolipidemic and hypouricemic action of fenofibrate in various types of hyperlipoproteinemias Artery 7 1980 73 82
18. D. Uetake, I. Ohno, and K. Ichida Effect of fenofibrate on uric acid metabolism and urate transporter 1 Intern Med 49 2010 89 94