메뉴 건너뛰기




Volumn 24, Issue 3, 2012, Pages 365-370

Tissue-engineering of the gastrointestinal tract

Author keywords

esophagus; gastrointestinal system; intestinal stem cell; large intestine; Lgr5; pediatric surgery; short bowel syndrome; small intestine; stomach; tissue engineering

Indexed keywords

ANUS; COLON; ESOPHAGUS; GASTROINTESTINAL DISEASE; GASTROINTESTINAL TRACT; GASTROINTESTINAL TRACT FUNCTION; HUMAN; NONHUMAN; NUTRITIONAL DEFICIENCY; PARENTERAL NUTRITION; PRIORITY JOURNAL; REVIEW; SHORT BOWEL SYNDROME; SMALL INTESTINE; STEM CELL; STOMACH; STOMACH CANCER; TISSUE ENGINEERING; TOTAL STOMACH RESECTION;

EID: 84861099980     PISSN: 10408703     EISSN: 1531698X     Source Type: Journal    
DOI: 10.1097/MOP.0b013e328352ec19     Document Type: Review
Times cited : (17)

References (45)
  • 1
    • 7044274593 scopus 로고    scopus 로고
    • Tissue-engineered small intestine improves recovery after massive small bowel resection
    • Grikscheit TC, Siddique A, Ochoa ER, et al. Tissue-engineered small intestine improves recovery after massive small bowel resection. Ann Surg 2004;240:748-754.
    • (2004) Ann Surg , vol.240 , pp. 748-754
    • Grikscheit, T.C.1    Siddique, A.2    Ochoa, E.R.3
  • 2
    • 2442557300 scopus 로고    scopus 로고
    • Neonatal short bowel syndrome: Populationbased estimates of incidence and mortality rates
    • Wales P, de Silva N, Kim J, et al. Neonatal short bowel syndrome: populationbased estimates of incidence and mortality rates. J Pediatr Surg 2004;39:690.
    • (2004) J Pediatr Surg , vol.39 , pp. 690
    • Wales, P.1    De Silva, N.2    Kim, J.3
  • 4
    • 79958036095 scopus 로고    scopus 로고
    • Prevalence of liver complications in children receiving long-term parenteral nutrition
    • Peyret B, Collardeau S, Touzet S, et al. Prevalence of liver complications in children receiving long-term parenteral nutrition. Eur J Clin Nutr 2011;65:743-749.
    • (2011) Eur J Clin Nutr , vol.65 , pp. 743-749
    • Peyret, B.1    Collardeau, S.2    Touzet, S.3
  • 6
    • 70350444697 scopus 로고    scopus 로고
    • The stem cells of the small intestinal crypts: Where are they?
    • Potten C, Gandara R, Mahida Y, et al. The stem cells of the small intestinal crypts: where are they? Cell Proliferation 2009;42:731-750.
    • (2009) Cell Proliferation , vol.42 , pp. 731-750
    • Potten, C.1    Gandara, R.2    Mahida, Y.3
  • 7
    • 0016325705 scopus 로고
    • Origin, differentiation and renewal of the four main epithelial cell types in the mouse small intestine. V. Unitarian theory of the origin of the four epithelial cell types
    • Cheng H, Leblond C. Origin, differentiation and renewal of the four main epithelial cell types in the mouse small intestine. V. Unitarian theory of the origin of the four epithelial cell types. Am J Anat 1974;141:537-562.
    • (1974) Am J Anat , vol.141 , pp. 537-562
    • Cheng, H.1    Leblond, C.2
  • 8
    • 0019486527 scopus 로고
    • The stem-cell zone of the small intestinal epithelium. I. Evidence from Paneth cells in the adult mouse
    • Bjerknes M, Cheng H. The stem-cell zone of the small intestinal epithelium. I. Evidence from Paneth cells in the adult mouse. Am J Anat 1981;160:51-63.
    • (1981) Am J Anat , vol.160 , pp. 51-63
    • Bjerknes, M.1    Cheng, H.2
  • 9
    • 84990581015 scopus 로고
    • Circadian variation in migration velocity in small intestinal epithelium
    • Kaur P, Potten C. Circadian variation in migration velocity in small intestinal epithelium. Cell Tissue Kinetics 1986;19:591-599.
    • (1986) Cell Tissue Kinetics , vol.19 , pp. 591-599
    • Kaur, P.1    Potten, C.2
  • 10
    • 0028673483 scopus 로고
    • Cell migration in the small and large bowel shows a strong circadian rhythm
    • Qiu J, Roberts S, Potten C. Cell migration in the small and large bowel shows a strong circadian rhythm. Epithelial Cell Biol 1994;3:137-148.
    • (1994) Epithelial Cell Biol , vol.3 , pp. 137-148
    • Qiu, J.1    Roberts, S.2    Potten, C.3
  • 11
    • 0032578019 scopus 로고    scopus 로고
    • Stem cells in gastrointestinal epithelium: Numbers, characteristics and death
    • Potten C. Stem cells in gastrointestinal epithelium: numbers, characteristics and death. Philos Trans R Soc B Biol Sci 1998;353:821-830.
    • (1998) Philos Trans R Soc B Biol Sci , vol.353 , pp. 821-830
    • Potten, C.1
  • 12
    • 35548974423 scopus 로고    scopus 로고
    • Identification of stem cells in small intestine and colon by marker gene Lgr5
    • Barker N, van Es JH, Kuipers J, et al. Identification of stem cells in small intestine and colon by marker gene Lgr5. Nature 2007;449:1003-1008.
    • (2007) Nature , vol.449 , pp. 1003-1008
    • Barker, N.1    Van Es, J.H.2    Kuipers, J.3
  • 13
    • 67349123408 scopus 로고    scopus 로고
    • Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche
    • Sato T, Vries RG, Snippert HJ, et al. Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche. Nature 2009;459:262-265.
    • (2009) Nature , vol.459 , pp. 262-265
    • Sato, T.1    Vries, R.G.2    Snippert, H.J.3
  • 14
    • 78751644734 scopus 로고    scopus 로고
    • Paneth cells constitute the niche for Lgr5 stem cells in intestinal crypts
    • Demonstrates that the Paneth cells support the Lgr5 + stem cell niche, as opposed to the mesenchyme, via expression of EGF, transforming growth factor TGF-α, Wnt3 and the Notch ligand Dll4
    • Sato T, van Es JH, Snippert H, et al. Paneth cells constitute the niche for Lgr5 stem cells in intestinal crypts. Nature 2011;469:415-418. Demonstrates that the Paneth cells support the Lgr5 (+) stem cell niche, as opposed to the mesenchyme, via expression of EGF, transforming growth factor (TGF)-α, Wnt3 and the Notch ligand Dll4.
    • (2011) Nature , vol.469 , pp. 415-418
    • Sato, T.1    Van Es, J.H.2    Snippert, H.3
  • 15
    • 46249128798 scopus 로고    scopus 로고
    • Bmi1 is expressed in vivo in intestinal stem cells
    • Sangiorgi E, Capecchi MR. Bmi1 is expressed in vivo in intestinal stem cells. Nature Genet 2008;40:915-920.
    • (2008) Nature Genet , vol.40 , pp. 915-920
    • Sangiorgi, E.1    Capecchi, M.R.2
  • 16
    • 80054041585 scopus 로고    scopus 로고
    • A reserve stem cell population in small intestine renders Lgr5-positive cells dispensable
    • Demonstrates Bmi1-expressing cells can repopulate the crypt base columnar cells after ablation of Lgr5 + cells, providing further evidence for the theory of two populations of intestinal stem cells, a quiescent and a rapidly cycling population
    • Tian H, Biehs B, Warming S, et al. A reserve stem cell population in small intestine renders Lgr5-positive cells dispensable. Nature 2011;478:255-259. Demonstrates Bmi1-expressing cells can repopulate the crypt base columnar cells after ablation of Lgr5 (+) cells, providing further evidence for the theory of two populations of intestinal stem cells, a quiescent and a rapidly cycling population.
    • (2011) Nature , vol.478 , pp. 255-259
    • Tian, H.1    Biehs, B.2    Warming, S.3
  • 17
    • 59049087696 scopus 로고    scopus 로고
    • Prominin 1 marks intestinal stem cells that are susceptible to neoplastic transformation
    • Zhu L, Gibson P, Currle DS, et al. Prominin 1 marks intestinal stem cells that are susceptible to neoplastic transformation. Nature 2009;457:603-607.
    • (2009) Nature , vol.457 , pp. 603-607
    • Zhu, L.1    Gibson, P.2    Currle, D.S.3
  • 18
    • 29344434237 scopus 로고    scopus 로고
    • Correlation between Musashi-1 and c-hairy-1 expression and cell proliferation activity in the developing intestine and stomach of both chicken and mouse
    • Asai R, Okan H, Yasugi S. Correlation between Musashi-1 and c-hairy-1 expression and cell proliferation activity in the developing intestine and stomach of both chicken and mouse. Dev Growth Differ 2005;47:501-510.
    • (2005) Dev Growth Differ , vol.47 , pp. 501-510
    • Asai, R.1    Okan, H.2    Yasugi, S.3
  • 19
    • 78651067425 scopus 로고    scopus 로고
    • Mouse telomerase reverse transcriptase (mTert) expression marks slowly cycling intestinal stem cells
    • Montgomery R, Carlone D, Richmond C, et al. Mouse telomerase reverse transcriptase (mTert) expression marks slowly cycling intestinal stem cells. Proc Natl Acad Sci 2011;108:179-184.
    • (2011) Proc Natl Acad Sci , vol.108 , pp. 179-184
    • Montgomery, R.1    Carlone, D.2    Richmond, C.3
  • 20
    • 70350239859 scopus 로고    scopus 로고
    • Doublecortin and CaM kinase-like-1 and leucine-rich-repeat-containing G-protein-coupled receptor mark quiescent and cycling intestinal stem cells, respectively
    • May R, Sureban SM, Hoang N, et al. Doublecortin and CaM kinase-like-1 and leucine-rich-repeat-containing G-protein-coupled receptor mark quiescent and cycling intestinal stem cells, respectively. Stem Cells 2009;27:2571-2579.
    • (2009) Stem Cells , vol.27 , pp. 2571-2579
    • May, R.1    Sureban, S.M.2    Hoang, N.3
  • 21
    • 80051546370 scopus 로고    scopus 로고
    • The physiological performance of a three-dimensional model that mimics the microenvironment of the small intestine
    • A three-dimensional, dynamic culture system improves in-vitro tissue-enginered intestine in comparision to traditional static culture systems
    • Pusch J, Votteler M, Gö hler S, et al. The physiological performance of a three-dimensional model that mimics the microenvironment of the small intestine. Biomaterials 2011;32:7469-7478. A three-dimensional, dynamic culture system improves in-vitro tissue-enginered intestine in comparision to traditional static culture systems.
    • (2011) Biomaterials , vol.32 , pp. 7469-7478
    • Pusch, J.1    Votteler, M.2    Hler, S.G.3
  • 22
    • 80051521183 scopus 로고    scopus 로고
    • Engineering of a multicellular organotypic model of the human intestinal mucosa
    • Produced an in-vitro epithelial lining, creating a novel method for studying intestinal cell signaling and response to infection
    • Salerno-Goncalves R, Fasano A, Sztein M. Engineering of a multicellular organotypic model of the human intestinal mucosa. Gastroenterology 2011;141:18-21. Produced an in-vitro epithelial lining, creating a novel method for studying intestinal cell signaling and response to infection.
    • (2011) Gastroenterology , vol.141 , pp. 18-21
    • Salerno-Goncalves, R.1    Fasano, A.2    Sztein, M.3
  • 23
    • 79551686425 scopus 로고    scopus 로고
    • Directed differentiation of human pluripotent stem cells into intestinal tissue in vitro
    • First to produce differentiated intestinal epithelial cells from induced pluripotent stem cells
    • Spence JR, Mayhew CN, Rankin SA, et al. Directed differentiation of human pluripotent stem cells into intestinal tissue in vitro. Nature 2011;470:105-109. First to produce differentiated intestinal epithelial cells from induced pluripotent stem cells.
    • (2011) Nature , vol.470 , pp. 105-109
    • Spence, J.R.1    Mayhew, C.N.2    Rankin, S.A.3
  • 24
    • 0023946928 scopus 로고
    • Selective cell transplantation using bioabsorbable artificial polymers as matrices
    • Vacanti J, Morse M, Saltzman W, et al. Selective cell transplantation using bioabsorbable artificial polymers as matrices. J Pediatr Surg 1988;23:3-9.
    • (1988) J Pediatr Surg , vol.23 , pp. 3-9
    • Vacanti, J.1    Morse, M.2    Saltzman, W.3
  • 25
    • 0026502307 scopus 로고
    • The development of a method for the preparation of rat intestinal epithelial cell primary cultures
    • Evans G, Flint N, Somers A, et al. The development of a method for the preparation of rat intestinal epithelial cell primary cultures. J Cell Sci 1992;101:219-231.
    • (1992) J Cell Sci , vol.101 , pp. 219-231
    • Evans, G.1    Flint, N.2    Somers, A.3
  • 26
    • 79959553073 scopus 로고    scopus 로고
    • A multicellular approach forms a significant amount of tissue-engineered small intestine in the mouse
    • Introduced this technique for growing tissue-engineered small intestine into a mouse model, a necessary step for accessing the transgenic strains and investigation techniques available in mice
    • Sala FG, Matthews JA, Speer AL, et al. A multicellular approach forms a significant amount of tissue-engineered small intestine in the mouse. Tissue Eng Part A 2011;17:1841-1850. Introduced this technique for growing tissue-engineered small intestine into a mouse model, a necessary step for accessing the transgenic strains and investigation techniques available in mice.
    • (2011) Tissue Eng Part A , vol.17 , pp. 1841-1850
    • Sala, F.G.1    Matthews, J.A.2    Speer, A.L.3
  • 27
    • 70249144629 scopus 로고    scopus 로고
    • Tissue-engineered small intestine and stomach form from autologous tissue in a preclinical large animal model
    • Sala FG, Kunisaki SM, Ochoa ER, et al. Tissue-engineered small intestine and stomach form from autologous tissue in a preclinical large animal model. J Surg Res 2009;156:205-212.
    • (2009) J Surg Res , vol.156 , pp. 205-212
    • Sala, F.G.1    Kunisaki, S.M.2    Ochoa, E.R.3
  • 28
    • 77951941622 scopus 로고    scopus 로고
    • Application of acellular dermal matrix for intestinal elongation in animal models
    • A scaffold interposition alone without cellular seeding does not promote intestinal ingrowth from the proximal and distal segments and cannot be used for bowel elongation
    • Xu HM, Wang ZJ, Han JG, et al. Application of acellular dermal matrix for intestinal elongation in animal models. World J Gastroenterol 2010;16:2023-2027. A scaffold interposition alone (without cellular seeding) does not promote intestinal ingrowth from the proximal and distal segments and cannot be used for bowel elongation.
    • (2010) World J Gastroenterol , vol.16 , pp. 2023-2027
    • Xu, H.M.1    Wang, Z.J.2    Han, J.G.3
  • 29
    • 54049101084 scopus 로고    scopus 로고
    • Intrathoracic eosphageal replacement by in situ tissue-engineered esophagus
    • Nakase Y, Nakamura T, Kin S, et al. Intrathoracic eosphageal replacement by in situ tissue-engineered esophagus. J Thorac Cardiovasc Surg 2008;136:850-859.
    • (2008) J Thorac Cardiovasc Surg , vol.136 , pp. 850-859
    • Nakase, Y.1    Nakamura, T.2    Kin, S.3
  • 30
    • 77952399663 scopus 로고    scopus 로고
    • Culture of ovine esophageal epithelial cells and in vitro esophagus tissue engineering
    • An esophageal epithelium grows on a collagen scaffold, a step toward growing fullthickness tissue-engineered esophagus
    • Saxena A, Ainoedhofer H, Hollwarth M. Culture of ovine esophageal epithelial cells and in vitro esophagus tissue engineering. Tissue Eng Part C 2010;16:109-114. An esophageal epithelium grows on a collagen scaffold, a step toward growing fullthickness tissue-engineered esophagus.
    • (2010) Tissue Eng Part C , vol.16 , pp. 109-114
    • Saxena, A.1    Ainoedhofer, H.2    Hollwarth, M.3
  • 31
    • 77951554598 scopus 로고    scopus 로고
    • Esophagus tissue engineering: In situ generation of rudimentary tubular vascularized esophageal conduit using the ovine model
    • Vascular ingrowth of an in-situ tissue-engineered esophagus demonstrates feasibility of providing blood supply to TEE
    • Saxena A, Baumgart H, Komann C, et al. Esophagus tissue engineering: in situ generation of rudimentary tubular vascularized esophageal conduit using the ovine model. J Pediatr Surg 2010;45:859-864. Vascular ingrowth of an in-situ tissue-engineered esophagus demonstrates feasibility of providing blood supply to TEE.
    • (2010) J Pediatr Surg , vol.45 , pp. 859-864
    • Saxena, A.1    Baumgart, H.2    Komann, C.3
  • 32
    • 77649242650 scopus 로고    scopus 로고
    • The development and characterization of an organotypic tissue-engineered human esophageal mucosal model
    • Identifies the ideal cellular source and scaffold for TEE among commonly used techniques
    • Green N, Huang Q, Kahn L, et al. The development and characterization of an organotypic tissue-engineered human esophageal mucosal model. Tissue Eng Part A 2010;16:1053-1064. Identifies the ideal cellular source and scaffold for TEE among commonly used techniques.
    • (2010) Tissue Eng Part A , vol.16 , pp. 1053-1064
    • Green, N.1    Huang, Q.2    Kahn, L.3
  • 34
    • 0037623972 scopus 로고    scopus 로고
    • A tissue-engineered stomach as a replacement of the native stomach
    • Maemura T, Shin M, Sato M, et al. A tissue-engineered stomach as a replacement of the native stomach. Transplantation 2003;76:61-65.
    • (2003) Transplantation , vol.76 , pp. 61-65
    • Maemura, T.1    Shin, M.2    Sato, M.3
  • 35
    • 0141565638 scopus 로고    scopus 로고
    • Tissue-engineered stomach: A preliminary report of a versatile in vivo model with therapeutic potential
    • Grikscheit T, Srinivasan A, Vacanti JP. Tissue-engineered stomach: a preliminary report of a versatile in vivo model with therapeutic potential. J Pediatr Surg 2003;38:1305-1309.
    • (2003) J Pediatr Surg , vol.38 , pp. 1305-1309
    • Grikscheit, T.1    Srinivasan, A.2    Vacanti, J.P.3
  • 36
    • 40149106666 scopus 로고    scopus 로고
    • A tissue-engineered stomach shows presence of proton pump and G-cells in a rat model, resulting in improved anemia following total gastrectomy
    • Maemura T, Shin M, Kinoshita M, et al. A tissue-engineered stomach shows presence of proton pump and G-cells in a rat model, resulting in improved anemia following total gastrectomy. Artif Organs 2008;32:234-239.
    • (2008) Artif Organs , vol.32 , pp. 234-239
    • Maemura, T.1    Shin, M.2    Kinoshita, M.3
  • 37
    • 73049116186 scopus 로고    scopus 로고
    • Lgr5+ve stem cells drive self-renewal in the stomach and build long-lived gastric units in vitro
    • Established Lgr5-expressing cells as markers of gastric stem cells
    • Barker N, Huch M, Kujala P, et al. Lgr5+ve stem cells drive self-renewal in the stomach and build long-lived gastric units in vitro. Cell Stem Cell 2010;6:25-36. Established Lgr5-expressing cells as markers of gastric stem cells.
    • (2010) Cell Stem Cell , vol.6 , pp. 25-36
    • Barker, N.1    Huch, M.2    Kujala, P.3
  • 38
    • 84861100965 scopus 로고    scopus 로고
    • Assessment of a tissueengineered gastric wall patch in a rat model
    • Epub ahead of print Demonstrates feasibility of treating gastric wall defect with a tissue-engineered stomach wall patch
    • Maemura T, Kinoshita M, Shin M, et al. Assessment of a tissueengineered gastric wall patch in a rat model. Artificial Organs 2011. [Epub ahead of print] Demonstrates feasibility of treating gastric wall defect with a tissue-engineered stomach wall patch.
    • (2011) Artificial Organs
    • Maemura, T.1    Kinoshita, M.2    Shin, M.3
  • 39
    • 84861096883 scopus 로고    scopus 로고
    • Murine tissue-engineered stomach demonstrates epithelial differentiation
    • First to grow tissue-engineered stomach in a mouse. A necessary step to determine the molecular and cellular mechanisms of this regenerative process
    • Speer AL, Sala FG, Matthews JA, Grikscheit TC. Murine tissue-engineered stomach demonstrates epithelial differentiation. J Surg Res 2011;156:205-212. First to grow tissue-engineered stomach in a mouse. A necessary step to determine the molecular and cellular mechanisms of this regenerative process.
    • (2011) J Surg Res , vol.156 , pp. 205-212
    • Speer, A.L.1    Sala, F.G.2    Matthews, J.A.3    Grikscheit, T.C.4
  • 40
    • 0041379897 scopus 로고    scopus 로고
    • Tissue-engineered large intestine resembles native colon with appropriate in vitro physiology and architecture
    • Grikscheit TC, Ochoa ER, Ramsanahie A, et al. Tissue-engineered large intestine resembles native colon with appropriate in vitro physiology and architecture. Ann Surg 2003;238:35-41.
    • (2003) Ann Surg , vol.238 , pp. 35-41
    • Grikscheit, T.C.1    Ochoa, E.R.2    Ramsanahie, A.3
  • 42
    • 72649101995 scopus 로고    scopus 로고
    • Surgical implantation of a bioengineered internal anal sphincter
    • Three-dimensional bioengineered internal anal sphincter can be generated
    • Hashish M, Raghavan S, Somara S, et al. Surgical implantation of a bioengineered internal anal sphincter. J Pediatr Surg 2010;45:52-58. Three-dimensional bioengineered internal anal sphincter can be generated.
    • (2010) J Pediatr Surg , vol.45 , pp. 52-58
    • Hashish, M.1    Raghavan, S.2    Somara, S.3
  • 43
    • 77955619031 scopus 로고    scopus 로고
    • Successful implantation of physiologically functional bioengineered mouse internal anal sphincter
    • Bioengineered internal anal sphincter demonstrates basal tone with appropriate contraction and relaxation to cholinergic, nitrergic, and vasoactive intestinal peptide VIP-ergic stimulation
    • Raghavan S, Miyasaka EA, Hashish M, et al. Successful implantation of physiologically functional bioengineered mouse internal anal sphincter. Am J Physiol Gastrointest Liver Physiol 2010;299:G430-G439. Bioengineered internal anal sphincter demonstrates basal tone with appropriate contraction and relaxation to cholinergic, nitrergic, and vasoactive intestinal peptide (VIP)-ergic stimulation.
    • (2010) Am J Physiol Gastrointest Liver Physiol , vol.299
    • Raghavan, S.1    Miyasaka, E.A.2    Hashish, M.3
  • 44
    • 78751666214 scopus 로고    scopus 로고
    • In vivo growth of a bioengineered internal anal sphincter: Comparison of growth factors for optimization of growth and survival
    • Growth factors, including PDGF a drug already approved for use in the United States and European Union, improve growth of tissue-engineered internal anal sphincter
    • Miyasaka E, Raghavan S, Gilmont RR, et al. In vivo growth of a bioengineered internal anal sphincter: comparison of growth factors for optimization of growth and survival. Pediatr Surg Int 2011;27:137-143. Growth factors, including PDGF (a drug already approved for use in the United States and European Union), improve growth of tissue-engineered internal anal sphincter.
    • (2011) Pediatr Surg Int , vol.27 , pp. 137-143
    • Miyasaka, E.1    Raghavan, S.2    Gilmont, R.R.3
  • 45
    • 79960004416 scopus 로고    scopus 로고
    • Successful implantation of bioengineered, intrinsically innervated, human internal anal sphincter
    • A bioengineered human internal anal sphincter can be grown with intact nerve, blood vessel and functioning muscle
    • Raghavan S, Gilmont RR, Miyasaka EA, et al. Successful implantation of bioengineered, intrinsically innervated, human internal anal sphincter. Gastroenterology 2011;141:310-319. A bioengineered human internal anal sphincter can be grown with intact nerve, blood vessel and functioning muscle.
    • (2011) Gastroenterology , vol.141 , pp. 310-319
    • Raghavan, S.1    Gilmont, R.R.2    Miyasaka, E.A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.