Molecular imaging of amyloidosis: Will the heart be the next target after the brain?

Current Cardiology Reports

Volumn 14, Issue 2, 2012, Pages 226-233

  Chen, Wengen ^a   Dilsizian, Vasken ^a  

^a UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

Author keywords

Amyloid plaques; Cardiac amyloidosis; Heart; Molecular imaging; PET; Radionuclide imaging; SPECT

Indexed keywords

(3 IODOBENZYL)GUANIDINE I 123; AMYLOID BETA PROTEIN; APROTININ TC 99M; BUTEDRONATE TECHNETIUM TC 99M; FLORBETABEN; FLORBETAPIR F 18; FLUTEMETAMOL F 18; IMCIROMAB PENTETATE; MEDRONATE TECHNETIUM TC 99M; PITTSBURGH COMPOUND B; PYROPHOSPHATE TECHNETIUM TC 99M; THIOFLAVINE; TRACER; UNCLASSIFIED DRUG;

ALZHEIMER DISEASE; AMYLOID PLAQUE; AMYLOIDOSIS; ARTICLE; BONE MARROW TRANSPLANTATION; CONGESTIVE CARDIOMYOPATHY; EARLY DIAGNOSIS; ECHOCARDIOGRAPHY; FAMILIAL AMYLOIDOSIS; HEART AMYLOIDOSIS; HEART INNERVATION; HEART MUSCLE BIOPSY; HUMAN; ISOTOPE LABELING; MOLECULAR IMAGING; NEUROIMAGING; POSITRON EMISSION TOMOGRAPHY; SINGLE PHOTON EMISSION COMPUTER TOMOGRAPHY;

3-IODOBENZYLGUANIDINE; AMYLOIDOSIS; EARLY DIAGNOSIS; FEMALE; FLUORESCENT DYES; HEART DISEASES; HUMANS; MALE; MOLECULAR IMAGING; POSITRON-EMISSION TOMOGRAPHY; RADIOPHARMACEUTICALS; TECHNETIUM TC 99M MEDRONATE; TECHNETIUM TC 99M PYROPHOSPHATE; THIAZOLES;

EID: 84861097318     PISSN: 15233782     EISSN: 15343170     Source Type: Journal    
DOI: 10.1007/s11886-011-0239-5     Document Type: Article

References (39)

1. Sipe JD, Benson MD, Buxbaum JN, et al. Amyloid fibril protein nomenclature: 2010 recommendations from the nomenclature committee of the International Society of Amyloidosis. Amyloid. 2010;17:101-4.
2. Kyle RA, Gertz MA. Primary systemic amyloidosis: clinical and laboratory features in 474 cases. Semin Hematol. 1995;32: 45-59. (Pubitemid 24370135)
3. Cornwell GG, Murdoch WL, Kyle RA, et al. Frequency and distribution of senile cardiovascular amyloid. A clinicopathologic correlation. Am J Med. 1983;75:618-23. (Pubitemid 13012155)
4. Jacobson DR, Pastore RD, Yaghoubian R, et al. Variant-sequence transthyretin (isoleucine 122) in late-onset cardiac amyloidosis in black Americans. N Engl J Med. 1997;336:466-73. (Pubitemid 27074357)
5. Desai HV, Aronow WS, Peterson SJ, et al. Cardiac amyloidosis: approaches to diagnosis and management. Cardiol Rev. 2010;18:1-11.
6. Dubrey SW, Cha K, Simms RW, et al. Electrocardiography and Doppler echocardiography in secondary (AA) amyloidosis. Am J Cardiol. 1996;77:313-5. (Pubitemid 26059307)
7. Biancalana M, Koide S. Molecular mechanism of Thioflavin-T binding to amyloid fibrils. Biochim Biophys Acta. 2010;1804:1405-12.
8. Serdons K, Verduyckt T, Vanderghinste D, et al. Synthesis of 18Flabelled 2-(4?-fluorophenyl)-1,3-benzothiazole and evaluation as amyloid imaging agent in comparison with [11C]PIB. Bioorg Med Chem Lett. 2009;19:602-5.
9. Klunk WE, Engler H, Nordberg A, et al. Imaging brain amyloid in Alzheimer's disease with Pittsburgh Compound-B. Ann Neurol. 2004;55:306-19. (Pubitemid 38269583)
10. Svedberg MM, Hall H, Hellstrom-Lindahl E, et al. [(11)C]PIBamyloid binding and levels of Abeta40 and Abeta42 in postmortem brain tissue from Alzheimer patients. Neurochem Int. 2009;54:347-57.
11. Lin KJ, Hsu WC, Hsiao IT, et al. Whole-body biodistribution and brain PET imaging with [18F]AV-45, a novel amyloid imaging agent-a pilot study. Nucl Med Biol. 2010;37:497-508.
12. Wong DF, Rosenberg PB, Zhou Y, et al. In vivo imaging of amyloid deposition in Alzheimer disease using the radioligand 18F-AV-45 (florbetapir [corrected] F18). J Nucl Med. 2010;51:913-20.
13. Clark CM, Schneider JA, Bedell BJ, et al. Use of florbetapir-PET for imaging beta-amyloid pathology. JAMA. 2011;305:275-83.
14. Wizenberg TA, Muz J, Sohn YH, et al. Value of positive myocardial technetium-99m-pyrophosphate scintigraphy in the noninvasive diagnosis of cardiac amyloidosis. Am Heart J. 1982;103:468-73. (Pubitemid 13137994)
15. Falk RH, Lee VW, Rubinow A, et al. Sensitivity of technetium- 99m-pyrophosphate scintigraphy in diagnosing cardiac amyloidosis. Am J Cardiol. 1983;51:826-30. (Pubitemid 13141976)
16. Gertz MA, Brown ML, Hauser MF, et al. Utility of technetium Tc 99m pyrophosphate bone scanning in cardiac amyloidosis. Arch Intern Med. 1987;147:1039-44. (Pubitemid 17113265)
17. Eriksson P, Backman C, Bjerle P, et al. Non-invasive assessment of the presence and severity of cardiac amyloidosis. A study in familial amyloidosis with polyneuropathy by cross sectional echocardiography and technetium-99m pyrophosphate scintigraphy. Br Heart J. 1984;52:321-6. (Pubitemid 14041671)
18. Hongo M, Yamada H, Okubo S, et al. Cardiac involvement in systemic amyloidosis: myocardial scintigraphic evaluation. J Cardiogr. 1985;15:163-80. (Pubitemid 15247374)
19. Ak I, Vardareli E, Erdin? O, et al. Myocardial Tc-99m MDP uptake on a bone scan in senile systemic amyloidosis with cardiac involvement. Clin Nucl Med. 2000;25:826-7.
20. Lee VW, Caldarone AG, Falk RH, et al. Amyloidosis of heart and liver: comparison of Tc-99m pyrophosphate and Tc-99m methylene diphosphonate for detection. Radiology. 1983;148:239-42. (Pubitemid 13107818)
21. Perugini E, Guidalotti PL, Salvi F, et al. Noninvasive etiologic diagnosis of cardiac amyloidosis using 99mTc-3,3-diphosphono- 1,2-propanodicarboxylic acid scintigraphy. J Am Coll Cardiol. 2005;46:1076-84. (Pubitemid 41316518)
22. Rapezzi C, Quarta CC, Guidalotti PL, et al. Usefulness and limitations of 99mTc-3,3-diphosphono-1,2-propanodicarboxylic acid scintigraphy in the aetiological diagnosis of amyloidotic cardiomyopathy. Eur J Nucl Med Mol Imaging. 2011;38:470-8.
23. Hawkins PN. Serum amyloid P component scintigraphy for diagnosis and monitoring amyloidosis. Curr Opin Nephrol Hypertens. 2002;11:649-55. (Pubitemid 35440848)
24. Hawkins PN, Lavender JP, Pepys MB. Evaluation of systemic amyloidosis by scintigraphy with 123I-labeled serum amyloid P component. N Engl J Med. 1990;323:508-13. (Pubitemid 20260051)
25. Hazenberg BP, van Rijswijk MH, Lub-de Hooge MN, et al. Diagnostic performance and prognostic value of extravascular retention of 123I-labeled serum amyloid P component in systemic amyloidosis. J Nucl Med. 2007;48:865-72. (Pubitemid 46909912)
26. Sojan SM, Smyth DR, Tsopelas C, et al. Pharmacokinetics and normal scintigraphic appearance of 99mTc aprotinin. Nucl Med Commun. 2005;26:535-9. (Pubitemid 40776421)
27. Aprile C, Marinone G, Saponaro R, et al. Cardiac and pleuropulmonary AL amyloid imaging with technetium-99m labelled aprotinin. Eur J Nucl Med. 1995;22:1393-401. (Pubitemid 26002917)
28. Schaadt BK, Hendel HW, Gimsing P, et al. 99mTc-aprotinin scintigraphy in amyloidosis. J Nucl Med. 2003;44:177-83.
29. Han S, Chong V, Murray T, et al. Preliminary experience of 99mTc-Aprotinin scintigraphy in amyloidosis. Eur J Haematol. 2007;79:494-500. (Pubitemid 350126671)
30. ChenW, Cao Q, Dilsizian V. Variation of heart-to-mediastinal ratio in (123)I-mIBG cardiac sympathetic imaging: its affecting factors and potential corrections. Curr Cardiol Rep. 2011;13:132-7.
31. Nakata T, Shimamoto K, Yonekura S, et al. Cardiac sympathetic denervation in transthyretin-related familial amyloidotic polyneuropathy: detection with iodine-123-MIBG. J Nucl Med. 1995;36:1040-2.
32. Tanaka M, Hongo M, Kinoshita O, et al. Iodine-123 metaiodobenzylguanidine scintigraphic assessment of myocardial sympathetic innervation in patients with familial amyloid polyneuropathy. J Am Coll Cardiol. 1997;29:168-74. (Pubitemid 27028735)
33. Hongo M, Urushibata K, Kai R, et al. Iodine-123 metaiodobenzylguanidine scintigraphic analysis of myocardial sympathetic innervation in patients with AL (primary) amyloidosis. Am Heart J. 2002;144:122-9. (Pubitemid 34734765)
34. Delahaye N, Dinanian S, Slama MS, et al. Cardiac sympathetic denervation in familial amyloid polyneuropathy assessed by iodine-123 metaiodobenzylguanidine scintigraphy and heart rate variability. Eur J Nucl Med. 1999;26:416-24. (Pubitemid 29176454)
35. Solomon A, Weiss DT, Wall JS. Immunotherapy in systemic primary (AL) amyloidosis using amyloid-reactive monoclonal antibodies. Cancer Biother Radiopharm. 2003;18:853-60. (Pubitemid 38064016)
36. Wall JS, Kennel SJ, Paulus M, et al. Radioimaging of light chain amyloid with a fibril-reactive monoclonal antibody. J Nucl Med. 2006;47:2016-24. (Pubitemid 47544990)
37. Wall JS, Paulus MJ, Gleason S, et al. Micro-imaging of amyloid in mice. Methods Enzymol. 2006;412:161-82. (Pubitemid 44548580)
38. Wall JS, Kennel SJ, Stuckey AC, et al. Radioimmunodetection of amyloid deposits in patients with AL amyloidosis. Blood. 2010;116:2241-4.
39. Lekakis J, Dimopoulos M, Nanas J, et al. Antimyosin scintigraphy for detection of cardiac amyloidosis. Am J Cardiol. 1997;80:963-5. (Pubitemid 27459180)