Evaluation of IPPSE, an alternative method for sequential population PKPD analysis

Journal of Pharmacokinetics and Pharmacodynamics

Volumn 39, Issue 2, 2012, Pages 177-193

  Lacroix, B D ^a,b   Friberg, L E ^a   Karlsson, M O ^a  

^a UPPSALA UNIVERSITY   (Sweden)

^b UCB PHARMA   (Belgium)

Author keywords

IPP; IPPSE; NONMEM 7; PKPD analysis; PPP D

Indexed keywords

ACCURACY; ANALYTIC METHOD; ANALYTICAL ERROR; ARTICLE; CLASSIFICATION ALGORITHM; COMPARTMENT MODEL; INFORMATION PROCESSING; INTERMETHOD COMPARISON; MATHEMATICAL COMPUTING; PHARMACODYNAMICS; POPULATION MODEL; PRIORITY JOURNAL; SIMULATION; STUDY DESIGN;

MODELS, BIOLOGICAL; PHARMACEUTICAL PREPARATIONS; PHARMACOKINETICS; RESEARCH DESIGN;

EID: 84861047324     PISSN: 1567567X     EISSN: 15738744     Source Type: Journal    
DOI: 10.1007/s10928-012-9240-x     Document Type: Article

References (13)

1. Zhang L, Beal SL, Sheiner LB (2003) Simultaneous vs. sequential analysis for population PK/PD Data I: best case performance. J Pharmacokin Pharmacodyn 30:387-403
2. Wade JR, Karlsson MO (1999) Combining PK and PD data during population PKPD analysis, p 8 Abstract 139 [www.pagemeeting. org/?abstract=139]
3. Savic RM, Karlsson MO (2009) Importance of shrinkage in empirical bayes estimates for diagnostics: problems and solutions. AAPS J 11:558-569
4. Beal S, Sheiner LB, Boeckmann A, Bauer RJ (1989, 2009) NONMEM user's guides, Icon Development Solutions, Ellicott City, MD, USA
5. Sheiner L, Wakefield J (1999) Population modelling in drug development. Stat Methods Med Res 8:183-193 (Pubitemid 30005352)
6. Beal S, Sheiner LB, Boeckmann A (1989, 2006) NONMEM user's guides, Icon Development Solutions, Ellicott City, MD, USA
7. Lindbom L, Pihlgren P, Jonsson EN (2005) PsN-Toolkit: a collection of computer intensive statistical methods for non-linear mixed effect modeling using NONMEM. Comput Methods Programs Biomed 79:241-257 (Pubitemid 41196689)
8. R Development Core Team (2008) R: a language and environment for statistical computing. R Foundation for Statistical Computing, Vienna, Austria. ISBN 3-900051-07-0, URL http://www. R-project.org
9. Gibaldi M, Perrier D (1982) Pharmacokinetics. Marcel Dekker, New York
10. Mouton JW, Dudley MN, Cars O, Derendorf H, Drusano GL (2005) Standardization of pharmacokinetic/pharmacodynamic (PK/PD) terminology for anti-infective drugs: an update. J Antimicrob Chemother 55:601-607 (Pubitemid 40691835)
11. Carnell R (2009) Latin hypercube samples package, http://cran. rproject.org/web/packages/lhs/index.html
12. Ueckert S, Johansson ÅM, Plan EL, Hooker AC, Karlsson MO (2010) p 19 Abstract 1915 [www.page-meeting.org/?abstract=1915]
13. Johansson ÅM, Ueckert S, Plan EL, Hooker AC, Karlsson MO (2010) p 19 Abstract 1922[www.page-meeting.org/?abstract=1922]