Macrophage-specific apoE gene repair reduces diet-induced hyperlipidemia and atherosclerosis in hypomorphic apoE mice

PLoS ONE

Volumn 7, Issue 5, 2012, Pages

  Gaudreault, Nathalie ^a   Kumar, Nikit ^a   Olivas, Victor R ^a   Eberlé, Delphine ^a   Rapp, Joseph H ^a   Raffai, Robert L ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

APOLIPOPROTEIN E; CD68 ANTIGEN; CHOLESTEROL; CRE RECOMBINASE; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; LOW DENSITY LIPOPROTEIN CHOLESTEROL; MESSENGER RNA; VERY LOW DENSITY LIPOPROTEIN CHOLESTEROL; VERY LOW DENSITY LIPOPROTEIN RECEPTOR;

ALLELE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; AORTA ATHEROSCLEROSIS; APOE GENE; ARTICLE; CELL SPECIFICITY; CHOLESTEROL BLOOD LEVEL; CONTROLLED STUDY; DISEASE ASSOCIATION; DNA REPAIR; EMBRYO; GENE; GENE EXPRESSION REGULATION; GENE FUNCTION; HOMEOSTASIS; HYPERLIPIDEMIA; IMMUNOREACTIVITY; KUPFFER CELL; LIPOPROTEIN BLOOD LEVEL; MACROPHAGE FUNCTION; MOUSE; NONHUMAN; PERITONEUM MACROPHAGE; PROTEIN EXPRESSION; WILD TYPE; ANIMAL; ATHEROGENIC DIET; ATHEROSCLEROSIS; BLOOD; GENE EXPRESSION; GENE THERAPY; GENETICS; MACROPHAGE; METABOLISM; MOUSE MUTANT; TRANSGENIC MOUSE;

MUS;

ANIMALS; APOLIPOPROTEINS E; ATHEROSCLEROSIS; CHOLESTEROL; DIET, ATHEROGENIC; GENE EXPRESSION; GENE THERAPY; HYPERLIPIDEMIAS; KUPFFER CELLS; MACROPHAGES; MICE; MICE, KNOCKOUT; MICE, TRANSGENIC; RNA, MESSENGER;

EID: 84861013397     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0035816     Document Type: Article

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