Battling fatigue in aviation: Recent advancements in research and practice

Journal of Medical Sciences

Volumn 32, Issue 2, 2012, Pages 47-56

  Lynn Caldwell, J ^a   Chandler, Joseph F ^a   Hartzler, Beth M ^a  

^a Naval Medical Research Unit Dayton   (United States)

Author keywords

Aviation; Individual differences; Recovery; Sleep deprivation; Sleep restriction

Indexed keywords

AVIATION; FATIGUE; HUMAN; JOB STRESS; OCCUPATIONAL HEALTH; PERSONNEL MANAGEMENT; REVIEW; RISK ASSESSMENT; RISK FACTOR; SLEEP DEPRIVATION; SLEEP PATTERN; SLEEP QUALITY; SLEEP TIME; WORK SCHEDULE; WORKING TIME;

EID: 84861012108     PISSN: 10114564     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (70)

1. Graybiel A, Brown N, Crispell R. A statistical analysis of the medical complaints of flying personnel at the Naval Air Station, Pensacola, Fla. DTIC Report AD0620281, 1943.
2. Graybiel A, Horwitz O, Gates D. The problem of fatigue among student pilots at the naval air training center, Pensacola, Florida. Aviation Med 1944:9-25.
3. National Transportation Safety Board. Evaluation of the U.S. Department of Transportation efforts in the 1990s to address operator fatigue. Safety Report NTSB/SR-99/01.
4. Davenport N. More fatigue! Approach 2009;May-June:3-6.
5. Luna T. Fatigue in context: USAF mishap experience. Aviat Space Environ Med 2003;74:388.
6. Caldwell JA, Gilreath SR. A survey of aircrew fatigue in a sample of U.S. Army aviation personnel. Aviat Space Environ Med 2002;73:472-480.
7. Federal Aviation Administration. Operational drivers of fatigue: National Transportation Safety Board Findings. In: Proceedings of the Aviation Fatigue Management Symposium: Partnerships for Solutions, 2008; Vienna, Virginia 2008:31-38.
8. Caldwell JA, Mallis MM, Caldwell JL, Paul MA, Miller JC, Neri DF. Fatigue countermeasures in aviation. Aviat Space Environ Med 2009;80:29-59.
9. Samel A, Wegmann HM, Vejvoda M. Jet lag and sleepiness in aircrew. J Sleep Res 1995;4(S2):30-36.
10. Neville HJ, Bisson RU, French J, Boll PA, Storm WF. Subjective fatigue of C-141 aircrews during Operation Desert Storm. Hum Factors 1994;36:339-349.
11. Banks S, Dinges DF. Chronic sleep deprivation. In MH Kryger, T Roth, WC Dement (Eds.) Principles and practice of sleep medicine - 5th edition. St. Louis: Saunders, 2011.
12. Lim J, Dinges DF. A meta-analysis of the impact of short-term sleep deprivation on cognitive variables. Psych Bull 2010 136:375-389.
13. Killgore WDS. Effects of sleep deprivation on cognition. In GA Kerkhof, HPA Van Dongen (Eds.) Progress in Brain Research 2010, Vol 185; pp.105-129.
14. Balkin TJ, Rupp T, Picchioni D, Wesensten NJ. Sleep loss and sleepiness Current issues. Chest 2008;134:653-660.
15. Durmer JS, Dinges DF. Neurocognitive consequences of sleep deprivation. Seminars in Neurology 2005;25:117-129.
16. Van Dongen HPA, Maislin G, Mullington JM, Dinges DF. The cumulative cost of additional wakefulness: Dose-response effects on neurobehavioral functions and sleep physiology from chronic sleep restriction and total sleep deprivation. Sleep 2003;26:117-126.
17. Banks S, Van Dongen HPA, Maislin G, Dinges DF. Neurobehavioral dynamics following chronic sleep restriction: Dose-response effects of one night for recovery. Sleep 2010;33:1013-1025.
18. Rupp TL, Wesensten NJ, Bliese PD, Balkin TJ. Banking sleep: Realization of benefits during subsequent sleep restriction and recovery. Sleep 2009;32:311-321.
19. Belenky G, Wesensten NJ, Thorne DR, Thomas ML, Sing HC, Redmond DP, Russo MB, Balkin TJ. Patterns of performance degradation and restoration during sleep restriction and subsequent recovery: A sleep dose-response study. J Sleep Res 2003;12:1-12.
20. Olofsen E, Van Dongen HPS, Mott, CG, Balkin TJ, Terman D. Current approaches and challenges to development of an individualized sleep and performance prediction model. Open Sleep J 2010;3:24-43.
21. Van Dongen HPS, Hursh SR. Fatigue, performance, errors, and accidents. In MH Kryger, T Roth, WC Dement (Eds.) Principles and Practice of Sleep Medicine (pp. 753-759). (5th Ed). 2010. Philadelphia: Elsevier Saunders.
22. Åkerstedt T, Ingre M, Kecklund G, Folkard S, Axelsson J. Accounting for partial sleep deprivation and cumulative sleepiness in the three-process model of alertness regulation. Chronobio Int 2008;25:309-319.
23. McCauley P, Kalachev LV, Smith AD, Belenky G, Dinges DF, Van Dongen HPA. A new mathematical model for homeostatic effects of sleep loss on neurobehavioral performance. J Theoretical Bio 2009;256:227-239.
24. Hursh SR, Van Dongen HPA. Fatigue and performance modeling. In MH Kryger, T Roth, WC Dement (Eds.) Principles and Practice of Sleep Medicine (pp. 745-752). (5th Ed). 2010. Philadelphia: Elsevier Saunders.
25. Axelsson J, Kecklund G, Åkerstedt T, Donofrio P, Lekander M, Ingre M. Sleepiness and performance in response to repeated sleep restriction and subsequent recovery during semi-laboratory conditions. Chronobiology Int 2008;25:297-308.
26. Dinges DF, Pack F, Williams K, Gillen KA, Powell JW, Ott GE, Aptowcz C, Pack AI. Cumulative sleepiness, mood disturbance, and psychomotor vigilance performance decrements during a week of sleep restricted to 4-5 hours per night. Sleep 1997;20:267-277.
27. Rupp, TL, Wesensten NJ, Balkin TJ. Sleep history affects task acquisition during subsequent sleep restriction and recovery. J Sleep Res 2010;19:289-297.
28. King AC, Belenky G, Van Dongen HPA. Performance impairment consequent to sleep loss: Determinants of resistance and susceptibility. Curr Opinion in Pulmo Med 2009;15:559-564.
29. Van Dongen HPA. Shift work and inter-individual differences in sleep and sleepiness. Chronobiology Int 2006;23:1139-1147.
30. Van Dongen HPA, Baynard MD, Maislin G, Dinges DF. Systematic interindividual differences in neurobehavioral impairment from sleep loss: Evidence of trait-like differential vulnerability. Sleep 2004;27:423-433.
31. Leproult R, Colecchia EF, Berardi AM, Stickgold R, Kosslyn SM, Van Cauter E. Individual differences in subjective and objective alertness during sleep deprivation are stable and unrelated. Am J Physiol Regul Integr Comp Physiol 2003;284:R280-R290.
32. Van Dongen HPA, Vitellaro KM, Dinges DF. Individual differences in adult human sleep and wakefulness: Leitmotif for a research agenda. Sleep 2005;28:479-496.
33. Harrison R, Chaiken S, Harville D, Fischer J, Fisher D, Whitmore J. The identification of fatigue resistant and fatigue susceptible individuals. AFRL-RH-BRTR- 2008-0050 2008; Brooks City-Base, TX: AFMC, AFRL.
34. Tucker AM, Dinges DF, Van Dongen HPA. Trait in terindividual differences in the sleep physiology of healthy young adults. J Sleep Res 2007;16:170-180.
35. Landolt HP. Genetic determination of sleep EEG profiles in healthy humans. In E. J. W. Van Someren et al (Eds.) Progress in Brain Research, Vol. 2011;193:51-61.
36. Viola AU, Archer SN, James LM, Groeger JA, Lo JCY, Skene DJ, von Schantz M, Dijk D. PER3 polymorphism predicts sleep structure and waking performance. Current Biology 2007;17:613-618.
37. Goel N, Banks S, Mignot E, Dinges DF. PER3 polymorphism predicts cumulative sleep homeostatic but not neurobehavioral changes to chronic partial sleep deprivation. PLoS One 2009;11:1-13.
38. Rupp TL, Killgore WDS, Balkin TJ. Socializing by day may affect performance by night: Vulnerability to sleep deprivation is differentially mediated by social exposure in extraverts vs introverts. Sleep 2010;33:1475-1485.
39. Goel N, Dinges DF. Behavioral and genetic markers of sleepiness. J Clin Sleep Med 2011;7:S19-S21.
40. Caldwell JA, Mu Q, Smith JK, Mishory A, Caldwell JL, Peters G, Brown DL, George MS. Are individual differences in fatigue vulnerability related to baseline differences in cortical activation? Behavioral Neuroscience 2005;119:694-707.
41. Mu Q, Mishory A, Johnson KA, Nahas Z, Zozel FA, Yamanaka K, Bohning DE, George MS. Decreased brain activation druing a working memory task at rested baseline is associated with vulnerability to sleep deprivation. Sleep 2005;28:433-446.
42. Chuah YML, Venkatraman V, Dinges DF, Chee, MWL. The neural basis of interindividual variability in inhibitory efficiency after sleep deprivation. J Neuroscience 2006;26:7156-7162.
43. Johnson DL, Wiebe JS, Gold SM, Andreasen NC, Hichwa RD, Watkins GL, Boles Ponto LL. Cerebral blood flow and personality: A positron emission tomography study. Am J Psychiatry 1999;156:252-257.
44. Killgore WS, Richards JM, Killgore DB, Kamimori GH, Balkin TJ. The trait of introversion-extraversion predicts vulnerability to sleep deprivation. J Sleep Res 2007;16:354-363.
45. Bliese PD, Wesensten N J, Balkin T J. Age and individual variability in performance during sleep restriction. J Sleep Res 2006;15;376-385.
46. Van Dongen HPA, Caldwell JA, Caldwell JL. Investigating systematic individual differences in sleep deprived performance on a high-fidelity flight simulator. Behavior Res Methods 2006;38:333-343.
47. Previc FH, Lopez N, Ercoline WR, Daluz CM, Workman AJ, Evans RH, Dillon NA. The effects of sleep deprivation on flight performance, instrument scanning, and physiological arousal in pilots. Int J Aviation Psych 2009;14:326-346.
48. Van Dongen HPA, Caldwell JA, Caldwell JL. Individual differences in cognitive vulnerability to fatigue in the laboratory and in the workplace. In Van Dongen HPA, Kerkhof GA, eds. Progress in Brain Research. Vol. 190. Amsterdam: Elsevier 2011:145-153.
49. Banks S, Dinges DF. Behavioral and physiological consequences of sleep restriction. J Clin Sleep Med 2007;3:519-528.
50. Killgore WS, Grugle NI, Reichardt RM, Killgore DB, Balkin TJ. Executive functions and the ability to sustain vigilance during sleep loss. Aviat Space Environ Med 2009; 80:81-87.
51. Webb WB, Levy CM. Effects of spaced and repeated total sleep deprivation. Ergonomics 1984;27:45-58.
52. Chandler JF. Predicting individual differences in response to sleep loss. NAMRU-D Research Information Bulletin No. 11-46 2011; Dayton, OH. DTIC ADA Report ADA549152.
53. Chandler JF, Arnold RD, Phillips JB, Lojewski RA, Horning DS. Preliminary validation of a readiness-to- fly assessment tool for use in Naval Aviation. NAMRL Technical Report 10-22 2010; Pensacola FL: NAMRL.
54. Federal Register. Flightcrew member duty and rest requirements. Federal Aviation Administration 2012;77:330-403.
55. International Civil Aviation Organization. Operation of Aircraft Part I International Commercial Air Transport - Aeroplanes. 2011
56. Civil Aviation Safety Authority (CASA). Biomathematical fatigue modeling in civil aviation fatigue risk management Application Guidance. March 2010.
57. Caldwell JA, Caldwell JL, Schmidt RM. Alertness management strategies for operational contexts. Sleep Med Rev 2008;12:257-273.
58. Driskell JE. The efficacy of naps as a fatigue countermeasure: A meta-analytic integration. Human Factors 2005;47:360-377.
59. Ficca G, Axelsson J, Mollicone DJ, Muto V, Vitiello MV. Naps, cognition and performance. Sleep Medicine Reviews 2010;14:249-258.
60. Lovato N, Lack L. The effects of napping on cognitive functioning. In GA Kerkhof and HPA Van Dongen (Eds.) Progress in Brain Research, Vol. 185;2010;Pgs. 155-166.
61. Brooks A, Lack L. A brief afternoon nap following nocturnal sleep restriction: Which nap duration is most recuperative? Sleep 2006;29:831-840.
62. Civil Aviation Administration. A review of in-flight napping strategies - Updated 2003. CAA Paper 2003/8. 1 September 2003.
63. Rosekind MR, Smith RM, Miller DL, Co EL, Gregory KB, Webbon LL, Gander PH, Lebacqz JV. Alertness management: strategic naps in operational settings. J Sleep Res 1995;4 (Suppl 2):62-66.
64. Graeber CR, Rosekind MR, Connell LJ, Dinges DF. Cockpit napping. ICAO Journal 1990;6-11.
65. Neri DF, Oyung RL, Colletti LM, Mallis MM, Tam PY, Dinges DF. Controlled breaks as a fatigue countermeasure on the flight deck. Aviat Space Environ Med. 2002;73:654-664.
66. Angus RG, Pigeau RA, Heslegrave RJ. Sustained-operations studies: from the field to the laboratory. In: Stampi C, ed. Why we nap. Birkhauser: Boston; 1992:217-241.
67. Cajochen C, Zeitzer JM, Czeisler CA, & Dijk DJ. Dose response relationship for light intensity and ocular and electroencephalographic correlates of human alertness. Behav Brain Res 2000;115:75-83.
68. Lockley SW, Evans EE, Scheer FA, Brainard GC, Czeisler CA, & Aeschbach D. Short-wavelength sensitivity for the direct effects of light on alertness, vigilance, and the waking electroencephalogram in humans. Sleep 2006;29:161-168.
69. Committee on Military Nutrition Research. Caffeine for the sustainment of mental task performance: Formulations for military operations. Washington, DC: National Academy Press 2001.
70. Russo MB. Recommendations for the ethical use of pharmacologic fatigue countermeasures in the U.S. military. Aviat Space Environ Med 2007;78(Suppl.):B119-127.