Methicillin-resistant Staphylococcus aureus ST398 contamination and transmission in pigs after a low dose inoculation

Letters in Applied Microbiology

Volumn 54, Issue 6, 2012, Pages 518-523

  Jouy, E ^a   Le Roux, A ^a   Keranflec'h A ^a   Granier, S A ^b   Laurent, F ^c   Kempf, I ^a   Brisabois, A ^b   Cariolet, R ^a   Chauvin, C ^a  

^a FRENCH AGENCY FOR FOOD   (France)

^b French Agency for Food   (France)

^c UNIVERSITÉ DE LYON   (France)

Author keywords

Lymph nodes; Methicillin resistant Staphylococcus aureus; Pig; Transmission

Indexed keywords

BACTERIA; BODY FLUIDS; MAMMALS;

COLONY FORMING UNITS; EXPERIMENTAL TRIALS; FAECAL SAMPLES; HORIZONTAL TRANSMISSIONS; LOW DOSE; LYMPH NODE; METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS; NEGATIVE CONTROL; PIG; ZOONOTIC AGENTS;

CONTAMINATION;

ANTIBIOTIC RESISTANCE; BACTERIUM; DOSE-RESPONSE RELATIONSHIP; EXCRETION; FECES; PIG; SAMPLING;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; AUTOPSY; BACTERIAL TRANSMISSION; BACTERIUM CONTAMINATION; BACTERIUM DETECTION; COLONY FORMING UNIT; CONTROLLED STUDY; LYMPH NODE; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; NONHUMAN; SWINE; TONSIL;

ANIMALIA; BACTERIA (MICROORGANISMS); METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; SUIDAE;

EID: 84860916625     PISSN: 02668254     EISSN: 1472765X     Source Type: Journal    
DOI: 10.1111/j.1472-765X.2012.03239.x     Document Type: Article

References (24)

1. Andraud, M., Rose, N., Laurentie, M., Sanders, P., Le Roux, A., Cariolet, R., Chauvin, C. and Jouy, E. (2011) Estimation of transmission parameters of a fluoroquinolone-resistant Escherichia coli strain between pigs in experimental conditions. Vet Res 42, 44.
2. Baele, M., Chiers, K., Devriese, L.A., Smith, H.E., Wisselink, H.J., Vaneechoutte, M. and Haesebrouck, F. (2001) The gram-positive tonsillar and nasal flora of piglets before and after weaning. J Appl Microbiol 91, 997-1003.
3. Broens, E.M., Graat, E.A., Van Der Wolf, P.J., Van De Giessen, A.W. and De Jong, M.C. (2011a) Transmission of methicillin resistant Staphylococcus aureus among pigs during transportation from farm to abattoir. Vet J 189, 302-305.
4. Broens, E.M., Graat, E.A., van der Wolf, P.J., van de Giessen, A.W., van Duijkeren, E., Wagenaar, J.A., van Nes, A., Mevius, D.J. et al. (2011b) MRSA CC398 in the pig production chain. Prev Vet Med 98, 182-189.
5. Broens, E.M., Graat, E.A., Engel, B., van Oosterom, R.A., van de Giessen, A.W. and van der Wolf, P.J. (2011c) Comparison of sampling methods used for MRSA-classification of herds with breeding pigs. Vet Microbiol 147, 440-444.
6. Broens, E.M., Graat, E.A., van de Giessen, A.W., Broekhuizen-Stins, M.J. and de Jong, M.C. (2012) Quantification of transmission of livestock-associated methicillin resistant Staphylococcus aureus in pigs. Vet Microbiol 155, 381-388.
7. Crombé, F., Vanderhaeghen, W., Dewulf, J., Hermans, K., Haesebrouck, F. and Butaye, P. (2012) Colonization and transmission of methicillin-resistant Staphylococcus aureus ST398 in nursery piglets. Appl Environ Microbiol 78, 1631-1634.
8. Dall'Antonia, M., Coen, P.G., Wilks, M., Whiley, A. and Millar, M. (2005) Competition between methicillin-sensitive and -resistant Staphylococcus aureus in the anterior nares. J Hosp Infect 61, 62-67.
9. van Duijkeren, E., Ikawaty, R., Broekhuizen-Stins, M.J., Jansen, M.D., Spalburg, E.C., de Neeling, A.J., Allaart, J.G., van Nes, A. et al. (2008) Transmission of methicillin-resistant Staphylococcus aureus strains between different kinds of pig farms. Vet Microbiol 126, 383-389.
10. EFSA (2010) Analysis of the baseline survey on the prevalence of methicillin-resistant Staphylococcus aureus (MRSA) in holdings with breeding pigs in the EU, part B: factors associated with MRSA contamination of holdings. EFSA J 8, 1597.
11. Garzoni, C. and Kelley, W.L. (2009) Staphylococcus aureus: new evidence for intracellular persistence. Trends Microbiol 17, 59-65.
12. Griffin, A.J., Li, L.X., Voedisch, S., Pabst, O. and McSorley, S.J. (2011) Dissemination of persistent intestinal bacteria via the mesenteric lymph nodes causes typhoid relapse. Infect Immun 79, 1479-1488.
13. Heller, J., Innocent, G.T., Denwood, M., Reid, S.W., Kelly, L. and Mellor, D.J. (2011) Assessing the probability of acquisition of meticillin-resistant Staphylococcus aureus (MRSA) in a dog using a nested stochastic simulation model and logistic regression sensitivity analysis. Prev Vet Med 99, 211-224.
14. Huijsdens, X.W., van Dijke, B.J., Spalburg, E., van Santen-Verheuvel, M.G., Heck, M.E., Pluister, G.N., Voss, A., Wannet, W.J. et al. (2006) Community-acquired MRSA and pig-farming. Ann Clin Microbiol Antimicrob 5, 26.
15. Khanna, T., Friendship, R., Dewey, C. and Weese, J.S. (2008) Methicillin resistant Staphylococcus aureus colonization in pigs and pig farmers. Vet Microbiol 128, 298-303.
16. Malhotra-Kumar, S., Abrahantes, J.C., Sabiiti, W., Lammens, C., Vercauteren, G., Ieven, M., Molenberghs, G., Aerts, M. et al. (2010) Evaluation of chromogenic media for detection of methicillin-resistant Staphylococcus aureus. J Clin Microbiol 48, 1040-1046.
17. Moodley, A., Latronico, F. and Guardabassi, L. (2011a) Experimental colonization of pigs with methicillin-resistant Staphylococcus aureus (MRSA): insights into the colonization and transmission of livestock-associated MRSA. Epidemiol Infect 139, 1594-1600.
18. Moodley, A., Nielsen, S.S. and Guardabassi, L. (2011b) Effects of tetracycline and zinc on selection of methicillin-resistant Staphylococcus aureus (MRSA) sequence type 398 in pigs. Vet Microbiol 152, 420-423.
19. de Neeling, A.J., van den Broek, M.J., Spalburg, E.C., van Santen-Verheuvel, M.G., Dam-Deisz, W.D., Boshuizen, H.C., van de Giessen, A.W., van Duijkeren, E. et al. (2007) High prevalence of methicillin resistant Staphylococcus aureus in pigs. Vet Microbiol 122, 366-372.
20. Sinha, B. and Fraunholz, M. (2010) Staphylococcus aureus host cell invasion and post-invasion events. Int J Med Microbiol 300, 170-175.
21. Smith, T.C., Male, M.J., Harper, A.L., Kroeger, J.S., Tinkler, G.P., Moritz, E.D., Capuano, A.W., Herwaldt, L.A. et al. (2009) Methicillin-resistant Staphylococcus aureus (MRSA) strain ST398 is present in midwestern U.S. swine and swine workers. PLoS ONE 4, e4258.
22. Szabó, I., Beck, B., Friese, A., Fetsch, A., Tenhagen, B.A. and Roesler, U. (2012) Colonization kinetics and host susceptibility of different Methicillin-resistant Staphylococcus aureus (MRSA) sequence types in pigs. Appl Environ Microbiol 78, 541-548.
23. Weese, J.S., Zwambag, A., Rosendal, T., Reid-Smith, R. and Friendship, R. (2011) Longitudinal investigation of methicillin-resistant Staphylococcus aureus in piglets. Zoonoses Public Health 58, 238-243.
24. Zhang, K., Sparling, J., Chow, B.L., Elsayed, S., Hussain, Z., Church, D.L., Gregson, D.B., Louie, T. et al. (2004) New quadriplex PCR assay for detection of methicillin and mupirocin resistance and simultaneous discrimination of Staphylococcus aureus from coagulase-negative staphylococci. J Clin Microbiol 42, 4947-4955.