α-Actinin-2 deficiency results in sarcomeric defects in zebrafish that cannot be rescued by α-actinin-3 revealing functional differences between sarcomeric isoforms

FASEB Journal

Volumn 26, Issue 5, 2012, Pages 1892-1908

  Gupta, Vandana ^a   Discenza, Marie ^a   Guyon, Jeffrey R ^a,b   Kunkel, Louis M ^a   Beggs, Alan H ^a  

^a BOSTON CHILDREN S HOSPITAL   (United States)

^b NATIONAL MARINE FISHERIES SERVICE   (United States)

Author keywords

Cytoskeletal; Evolution; Gene duplication; Myofibrillogenesis; Skeletal muscle

Indexed keywords

ACTIN BINDING PROTEIN; ALPHA ACTININ 2; ALPHA ACTININ 3; CALCIUM; MESSENGER RNA;

ACTN2 GENE; ACTN3 GENE; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CYTOSKELETON; DEVELOPMENTAL STAGE; EMBRYO; GENE; GENE EXPRESSION PROFILING; GENE OVEREXPRESSION; GENETIC CONSERVATION; GENOME ANALYSIS; HEART MUSCLE; IN SITU HYBRIDIZATION; INVERTEBRATE; MALE; MOLECULAR EVOLUTION; NONHUMAN; NUCLEOTIDE SEQUENCE; PHENOTYPE; PRIORITY JOURNAL; PROTEIN DEFICIENCY; SARCOMERE; SKELETAL MUSCLE; ZEBRA FISH;

ACTININ; ANIMALS; BASE SEQUENCE; BLOTTING, WESTERN; DNA PRIMERS; FLUORESCENT ANTIBODY TECHNIQUE, INDIRECT; HUMANS; IN SITU HYBRIDIZATION; PHYLOGENY; PROTEIN ISOFORMS; REAL-TIME POLYMERASE CHAIN REACTION; SARCOMERES; ZEBRAFISH;

DANIO RERIO; INVERTEBRATA;

EID: 84860907995     PISSN: 08926638     EISSN: 15306860     Source Type: Journal    
DOI: 10.1096/fj.11-194548     Document Type: Article

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