A novel extract from bovine colostrum whey supports anti-bacterial and anti-viral innate immune functions in vitro and in vivo. I. Enhanced immune activity in vitro translates to improved microbial clearance in animal infection models.

Preventive Medicine

Volumn 54, Issue SUPPL., 2012, Pages

  Benson, Kathleen F ^a   Carter, Steve G ^a   Patterson, Kelly M ^a   Patel, Dilip ^b,c   Jensen, Gitte S ^a  

^a NIS Labs   (United States)

^b SOUTH DAKOTA STATE UNIVERSITY   (United States)

^c Sterling Technology Inc   (United States)

Author keywords

Bacterial; Dendritic; Immunity; Infection; Innate; Macrophage; Maturation; Phagocytosis; Proline rich polypeptide; Viral

Indexed keywords

B7 ANTIGEN; CD69 ANTIGEN; CD86 ANTIGEN;

ANIMAL EXPERIMENT; ANTIBACTERIAL ACTIVITY; ANTIGEN EXPRESSION; ANTIVIRAL ACTIVITY; ARTICLE; BACTERIAL LOAD; CELL MATURATION; CELL MIGRATION; CHEMOTAXIS; COLOSTRUM; COLOSTRUM LOW MOLECULAR WEIGHT FRACTION; COW; DENDRITIC CELL; FEMALE; IMMUNITY; IN VITRO STUDY; IN VIVO STUDY; INFLUENZA; INNATE IMMUNITY; MOUSE; NATURAL KILLER CELL; NONHUMAN; PATHOGEN CLEARANCE; PERIPHERAL BLOOD MONONUCLEAR CELL; PHAGOCYTOSIS; POLYMORPHONUCLEAR CELL; PRIORITY JOURNAL; STREPTOCOCCUS; T LYMPHOCYTE ACTIVATION; VIRUS LOAD; WHEY;

ANIMALS; ANTIGENS, CD; CATTLE; COLOSTRUM; DISEASE MODELS, ANIMAL; IMMUNITY, INNATE; KILLER CELLS, NATURAL; MICE; MICROBIAL VIABILITY; MILK PROTEINS; ORTHOMYXOVIRIDAE INFECTIONS; PHAGOCYTOSIS; STREPTOCOCCAL INFECTIONS; VIRAL LOAD;

EID: 84860884658     PISSN: 00917435     EISSN: 10960260     Source Type: Journal    
DOI: 10.1016/j.ypmed.2011.12.023     Document Type: Article

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