Paraoxonase and arylesterase activities in children with iron deficiency anemia and vitamin B 12 deficiency anemia

Pediatric Hematology and Oncology

Volumn 29, Issue 4, 2012, Pages 345-353

  Koc, Ahmet ^a   Cengiz, Murad ^a   Ozdemir, Zeynep Canan ^a   Celik, Hakim ^a  

^a HARRAN UNIVERSITY   (Turkey)

Author keywords

Arylesterase; Children; Iron deficiency anemia; Paraoxonase; Vitamin B12 deficiency anemia

Indexed keywords

ARYLDIALKYLPHOSPHATASE; ARYLESTERASE; CYANOCOBALAMIN;

ARTICLE; CHILD; CONTROLLED STUDY; CORRELATION ANALYSIS; ENZYME ACTIVITY; ENZYME BLOOD LEVEL; FEMALE; HUMAN; INFANT; IRON DEFICIENCY ANEMIA; IRON THERAPY; MAJOR CLINICAL STUDY; MALE; PERNICIOUS ANEMIA; PRESCHOOL CHILD; SPECTROPHOTOMETER;

ANEMIA, IRON-DEFICIENCY; ARYLDIALKYLPHOSPHATASE; CARBOXYLIC ESTER HYDROLASES; CHILD; CHILD, PRESCHOOL; FEMALE; HUMANS; INFANT; IRON; MALE; VITAMIN B 12; VITAMIN B 12 DEFICIENCY; VITAMIN B COMPLEX;

EID: 84860850598     PISSN: 08880018     EISSN: 15210669     Source Type: Journal    
DOI: 10.3109/08880018.2011.645185     Document Type: Article

References (55)

1. Mackness B,Durrington PN,Mackness MI.Human serumparaoxonase. GenPharm. 1998;3:329-336.
2. Aviram M, Hardak E, Vaya J, et al. Human serum paraoxonases (PON1) Q and R selectively decrease lipid peroxides in human coronary and carotid atherosclerotic lesions. Circulation. 2000;101:2510-2517.
3. Canales A, Sanchez-Muniz FJ. Paraoxanase, something more than an enzyme? Med Clin. 2003;121:537-548.
4. Bodolay E, Seres I, Szodoray P, et al. Evaluation of paraoxonase activity in patients with mixed connective tissue disease. J Rheumatol. 2008;35:237-243.
5. Kiss E, Seres I, Tarr T, et al. Reduced paraoxonase1 activity is a risk for atherosclerosis in patientswith systemic lupus erythematosus. Ann N Y Acad Sci. 2007;1108:83-91.
6. Aviram M, Rosenblat M, Billecke S, et al. Human serum paraoxonase (PON 1) is inactivated by oxidized low density lipoprotein and preserved by antioxidants. Free Radic Biol Med. 1999;26:892-904.
7. Sumegová K, Nagyová Z, Waczulíková I, et al. Activity of paraoxonase 1 and lipid profile in healthy children. Physiol Res. 2007;56:351-357.
8. Taylor PG,Martinez-Torres C,Mendez-Castellano H, et al.The relationship between iron deficiency and anemia in Venezuelan children. Am J Clin Nutr. 1993;58:215-218.
9. Bortolini GA, VitoloMR. Relationship between iron deficiency and anemia in children younger than 4 years. J Pediatr (Rio J). 2010;86:488-492.
10. Milman N. Anemia-still a major health problem in many parts of the world! Ann Hematol. 2011;90:369-377.
11. Looker AC, Dallman PR, Carroll MD, et al. Prevalence of iron deficiency in the United States. JAMA. 1997;277:973-976.
12. Prasad AN, Prasad C Iron deficiency; non-hematological manifestations. Prog Food Nutr Sci. 1991;15:255-283.
13. RoncaglioloM, Garrido M, Walter T, et al. Evidence of altered central nervous system development in infants with iron deficiency anemia at 6 mo: delayedmaturation of auditory brainstem responses. Am J Clin Nutr. 1998;68:683-690.
14. Madan N, Rusia U, Sikka M, et al. Developmental and neurophysiologic deficits in iron deficiency in children. Indian J Pediatr. 2011;78:58-64.
15. Pala E, Erguven M, Guven S, et al. Psychomotor development in children with iron deficiency and iron-deficiency anemia. Food Nutr Bull. 2010;31:431-435.
16. Cetinkaya F, Yildirmak Y, Kutluk G, Erdem E. Nutritional vitamin B12 deficiency in hospitalized young children. Pediatr Hematol Oncol. 2007;24:15-21.
17. Zengin E, Sarper N, Caki Kiliç S. Clinicalmanifestations of infants with nutritional vitamin B12 deficiency due tomaternal dietary deficiency. Acta Paediatr. 2009;98:98-102.
18. Ramussen SA, Fernboff PM, Scanlon KS. Vitamin B12 deficiency in children and adolescents. J Pediatr. 2001;138:10-17.
19. Teneja S, Bhandari N, Strand TA, et al. Cobalamin and folate status in infants and young children in a low-to-middle income community in India. Am J Clin Nutr. 2007;86:1302-1309.
20. Jones KM, Ramirez-Zea M, Zuleta C, Allen LH. Prevalent vitamin B-12 deficiency in twelvemonth- old Guatemalan infants is predicted by maternal B-12 deficiency and infant diet. J Nutr. 2007;137:1307-1313.
21. Koc A, Kocyigit A, Soran M, et al.High frequency ofmaternal vitamin B12 deficiency as an important cause of infantile vitamin B12 deficiency in Sanliurfa Province of Turkey. Eur J Nutr. 2006;45:291-297.
22. Koc A, Ertas T, Tatli MM, Kocyigit A. The frequency of vitamin B12 deficiency in 6-12 months-old children in Sanliurfa and its relation with children's nutrition and with the deficiency in mothers. J Turk Pediatr Hematol. In press.
23. Watkins D,Whitehead VM, Rosenblatt DS.Megaloblastic anemia. In: Orkin SH, Fisher DE, Look AT, et al., eds. Nathan and Oski's Hematology of Infancy and Childhood. 7th ed. Philadelphia: Saunders Elsevier; 2009:469-521.
24. Honzik T, Adamovicova M, Smolka V, et al. Clinical presentation and metabolic consequences in 40 breastfed infants with nutritional vitamin B12 deficiency-what have we learned? Eur J Paediatr Neurol. 2010;14:488-495.
25. Incecik F, Hergüner MO, Altunbasak S, Leblebisatan G. Neurologic findings of nutritional vitamin B12 deficiency in children. Turk J Pediatr. 2010;52:17-21.
26. Grattan-Smith PJ, Wilcken B, Procopis PG, Wise GA.The neurological syndrome of infantile cobalamin deficiency: developmental regression and involuntary movements. Mov Disord. 1997;12: 39-46.
27. AslanM, Kosecik M,HorozM, et al. Assessment of paraoxonase and arylesterase activities in patients with iron deficiency anemia. Atherosclerosis. 2007;191:397-402.
28. Brugnara C, Oski FA,NathanDG. DiagnosticApproach to the Anemic Patient In: Orkin SH, Fisher DE, Look AT, et al., eds. Nathan and Oski's Hematology of Infancy and Chilhood. 7th ed. Philadelphia: Saunders Elsevier; 2009:456-468.
29. Eckerson HW, Wyte MC, La, Du BN. The human serum paraoxonase/arylesterase polymorphism. Am J Hum Genet. 1983;35:1126-1138.
30. Haagen L, Brock A. A new automated method for phenotyping arylesterase (E.C.3.1.1.2) based upon inhibition of enzymatic hydrolysis or 4-nitrophenyl acetate by phenyl acetate. Eur J Clin Chem Clin Biochem. 1992;30:391-395.
31. Bhattacharyya T, Nicholls SJ, Topol EJ, et al. Relationship of paraoxonase 1 (PON1) gene polymorphisms and functional activity with systemic oxidative stress and cardiovascular risk. JAMA. 2008;299:1265-1276.
32. Samra ZQ, Sana A, Bano S, et al. Immunobiochemical analysis of Paraoxonase1 (anti-oxidant), xanthine oxidase (oxidant) enzymes and lipid profile of cardiac disease patients in LahoreMetropolitan, Pakistan. J Clin Lab Anal. 2010;24:348-356.
33. Yildiz A, Sezen Y,Gur M, et al.Association of paraoxonase activity and coronary collateral flow. Coron Artery Dis. 2008;19:441-447.
34. Szántó A, Harangi M, Seres I, et al. Decreased human paraoxonase-1 activity in patients with Sjögren's syndrome. Int Immunol. 2010;22:605-609.
35. Isik A, Koca SS, Ustundag B, et al. Paraoxonase and arylesterase levels in rheumatoid arthritis. Clin Rheumatol. 2007;26:342-348.
36. Selek S, Cosar N, Kocyigit A, et al. PON1 activity and total oxidant status in patients with active pulmonary tuberculosis. Clin Biochem. 2008;41:140-144.
37. Cakmak A, Soker M, Koc A, Erel O, Paraoxonase and arylesterase activity with oxidative status in children with thalassemiamajor. J Pediatr Hematol Oncol. 2009;31:583-587.
38. Whitehead VM. Acquired and inherited disorders of cobalamin and folate in children. Br JHaematol. 2006;134:125-136.
39. Sadeghian S, Fallahi F, Salarifar M, et al. Homocysteine, vitamin B12 and folate levels in premature coronary artery disease. BMC Cardiovasc Disord. 2006;26:38-41.
40. Wehr H, Bednarska-Makaruk M, Graban A, et al. Paraoxonase activity and dementia. J Neurol Sci. 2009;283:107-108.
41. Ates O, Azizi S, Alp HH, et al. Decreased serum paraoxonase 1 activity and increased serum homocysteine and malondialdehyde levels in age-related macular degeneration. Tohoku J Exp Med. 2009;217:17-22.
42. Weijun G, Juming L, Guoqing Y, et al. Effects of plasma homocysteine levels on serum HTase/PON activity in patients with type 2 diabetes. Adv Ther. 2008;25:884-893.
43. Karikas GA, Kriebardis A, Samara I, et al. Serum homocysteine levels and paraoxonase 1 activity in preschool aged children in Greece. Clin Chem LabMed. 2006;44:623-327.
44. Stary HC. Evolution and progression of atherosclerotic lesions in coronary arteries of children and young adults. Arteriosclerosis. 1989;9(1 Suppl):19-32.
45. Freedman DS, Patel DA, Srinivasan SR, et al. The contribution of childhood obesity to adult carotid intima-media thickness: the Bogalusa Heart Study. Int J Obes (Lond). 2008;32:749-756.
46. Daniels SR, Greer FR; Committee on Nutrition. Lipid screening and cardiovascular health in childhood. Pediatrics. 2008;122:198-208.
47. Lanigan J, Singhal A. Early nutrition and long-term health: a practical approach. Proc Nutr Soc. 2009;68:422-429.
48. Girardet JP, Rieu D, Bocquet A, et al. Childhood diet and cardiovascular risk factors. Arch Pediatr. 2010;17:51-59.
49. Singhal A.The early origins of atherosclerosis. Adv Exp Med Biol. 2009;646:51-58.
50. Martin RM, Ebrahim S, Griffin M, et al. Breastfeeding and atherosclerosis: intima-media thickness and plaques at 65-year follow-up of the Boyd Orr cohort. Arterioscler Thromb Vasc Biol. 2005;25:1482-1488.
51. Seres I, Bajnok L, Harangi M, et al. Alteration of PON1 activity in adult and childhood obesity and its relation to adipokine levels. Adv Exp Med Biol. 2010;660:129-142.
52. Koncsos P, Seres I, HarangiM, et al. Human paraoxonase-1 activity in childhood obesity and its relation to leptin and adiponectin levels. Pediatr Res. 2010;67:309-313.
53. Martinelli N,Micaglio R, Consoli L, et al. Lowlevels of serumparaoxonase activities are characteristic of metabolic syndrome and may influence the metabolic-syndrome-related risk of coronary artery disease. Exp Diabetes Res. 2012; 2012:231502. Epub 2011 Sep 22.
54. Jarvik GP, Tsai NT, McKintry LA, et al. Vitamin C and E intake is associated with increased paraoxonase activity. Arterioscler Thromb Vasc Biol. 2002;22:1329-1333.
55. Lixandru D, Mohora M, Coman A, et al. Diet and paraoxonase 1 enzymatic activity in diabetic foot patients from Romania and Belgium: favorable association of high flavonoid dietary intake with arylesterase activity. Ann NutrMetab. 2010;56:294-301.