Relationship of Race/Ethnicity and Survival after Single Umbilical Cord Blood Transplantation for Adults and Children with Leukemia and Myelodysplastic Syndromes

Biology of Blood and Marrow Transplantation

Volumn 18, Issue 6, 2012, Pages 903-912

  Ballen, Karen K ^a   Klein, John P ^b   Pedersen, Tanya L ^c   Bhatla, Deepika ^d   Duerst, Reggie ^e   Kurtzberg, Joanne ^f   Lazarus, Hillard M ^g   LeMaistre, Charles F ^h   McCarthy, Phillip ⁱ   Mehta, Paulette ^j   Palmer, Jeanne ^k   Setterholm, Michelle ^l   Wingard, John R ^m   Joffe, Steven ⁿ   Parsons, Susan K ^o   Switzer, Galen E ^p   Lee, Stephanie J ^q   Rizzo, J Douglas ^b   Majhail, Navneet S ^c,r  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b MEDICAL COLLEGE OF WISCONSIN   (United States)

^c CENTER FOR INTERNATIONAL BLOOD AND MARROW TRANSPLANT RESEARCH   (United States)

^d SAINT LOUIS UNIVERSITY   (United States)

^e CHILDREN'S MEMORIAL HOSPITAL   (United States)

^f DUKE UNIVERSITY MEDICAL CENTER   (United States)

^g UNIVERSITY HOSPITALS OF CLEVELAND   (United States)

^h TEXAS TRANSPLANT INSTITUTE   (United States)

ⁱ ROSWELL PARK CANCER INSTITUTE   (United States)

^j UNIVERSITY OF ARKANSAS AT LITTLE ROCK   (United States)

^k Children's Hospital of Wisconsin   (United States)

^l NATIONAL MARROW DONOR PROGRAM   (United States)

^m UNIVERSITY OF FLORIDA   (United States)

ⁿ DANA FARBER CANCER INSTITUTE   (United States)

^o TUFTS MEDICAL CENTER   (United States)

^p UNIVERSITY OF PITTSBURGH CANCER INSTITUTE   (United States)

^q USA   (United States)

^r UNIVERSITY OF MINNESOTA   (United States)

more..

Author keywords

Ethnicity; Leukemia; Myelodysplastic syndrome; Race; Transplantation; Umbilical cord blood

Indexed keywords

ADOLESCENT; ADULT; AGED; ARTICLE; CANCER SURVIVAL; CAUCASIAN; CELL COUNT; CHILD; CHILDHOOD LEUKEMIA; COHORT ANALYSIS; CONTROLLED STUDY; CORD BLOOD STEM CELL TRANSPLANTATION; ETHNICITY; FEMALE; HISPANIC; HUMAN; INFANT; LEUKEMIA; MAJOR CLINICAL STUDY; MALE; MYELODYSPLASTIC SYNDROME; NEGRO; OUTCOME ASSESSMENT; OVERALL SURVIVAL; PRESCHOOL CHILD; RETROSPECTIVE STUDY; SCHOOL CHILD; UMBILICAL CORD BLOOD TRANSPLANTATION;

ADOLESCENT; ADULT; AFRICAN CONTINENTAL ANCESTRY GROUP; AGE FACTORS; AGED; CELL COUNT; CHILD; CHILD, PRESCHOOL; CORD BLOOD STEM CELL TRANSPLANTATION; DISEASE-FREE SURVIVAL; EUROPEAN CONTINENTAL ANCESTRY GROUP; FEMALE; FETAL BLOOD; HISPANIC AMERICANS; HISTOCOMPATIBILITY TESTING; HLA ANTIGENS; HUMANS; INFANT; LEUKEMIA; MALE; MIDDLE AGED; MYELODYSPLASTIC SYNDROMES; RETROSPECTIVE STUDIES; TREATMENT OUTCOME; UNITED STATES;

EID: 84860838979     PISSN: 10838791     EISSN: 15236536     Source Type: Journal    
DOI: 10.1016/j.bbmt.2011.10.040     Document Type: Article

References (32)

1. Ballen K.K. New trends in umbilical cord blood transplantation. Blood 2005, 105:3786-3792.
2. Wagner J.E., Barker J.N., DeFor T.E., et al. Transplantation of unrelated donor umbilical cord blood in 102 patients with malignant and nonmalignant diseases: influence of CD34 cell dose and HLA disparity on treatment-related mortality and survival. Blood 2002, 100:1611-1618.
3. Laughlin M.J., Eapen M., Rubinstein P., et al. Outcomes after transplantation of cord blood or bone marrow from unrelated donors in adults with leukemia. N Engl J Med 2004, 351:2265-2275.
4. Eapen M., Rubinstein P., Zhang M.J., et al. Outcomes of transplantation of unrelated donor umbilical cord blood and bone marrow in children with acute leukaemia: a comparison study. Lancet 2007, 369:1947-1954.
5. Eapen M., Rocha V., Sanz G., et al. Effect of graft source on unrelated donor haematopoietic stem-cell transplantation in adults with acute leukemia: a retrospective analysis. Lancet Oncol 2010, 11:653-660.
6. Davies S.M., Kollman C., Anasetti C., et al. Engraftment and survival after unrelated-donor bone marrow transplantation: a report from the National Marrow Donor Program. Blood 2000, 96:4096-4102.
7. Serna D.S., Lee S.J., Zhang M.J., et al. Trends in survival rates after allogeneic hematopoietic stem-cell transplantation for acute and chronic leukemia by ethnicity in the United States and Canada. J Clin Oncol 2003, 21:3756-3760.
8. Oh H., Loberiza F.R., Zhang M.J., et al. Comparison of graft-versus-host-disease and survival after HLA-identical sibling bone marrow transplantation in ethnic populations. Blood 2005, 105:1408-1416.
9. Baker K.S., Davies S.M., Majhail N.S., et al. Race and socioeconomic status influence outcomes of unrelated donor hematopoietic cell transplantation. Biol Blood Marrow Transplant 2009, 15:1543-1554.
10. Ballen K.K., Kurtzberg J., Lane T.A., et al. Racial diversity with high nucleated cell counts and CD34 counts achieved in national network of cord blood banks. Biol Blood Marrow Transplant 2004, 10:269-275.
11. Cairo M.S., Wagner E.L., Fraser J., et al. Characterization of banked umbilical cord blood hematopoietic progenitor cells and lymphocyte subsets and correlation with ethnicity, birth weight, sex, and type of delivery: a Cord Blood Transplantation (COBLT) study report. Transfusion 2005, 45:856-866.
12. Ballen K.K., Haley N.R., Kurtzberg J., et al. Outcomes of 122 diverse adult and pediatric cord blood transplant recipients from a large cord blood bank. Transfusion 2006, 46:2063-2070.
13. Office of Management and Budget Revisions to the Standards for the Classification of Federal Data on Race and Ethnicity, Available at:, Accessed February 25, 2011. http://www.whitehouse.gov/omb/fedreg_1997standards/.
14. Farag S.S., Bacigalupo A., Eapen M., et al. The effect of KIR ligand incompatibility on the outcome of unrelated donor transplantation: a report from the Center for International Blood and Marrow Transplant Research, the European Blood and Marrow Transplant Registry, and the Dutch Registry. Biol Blood Marrow Transplant 2006, 12:876-884.
15. Clark T.G., Altman D.G., De Stavola B.L. Quantification of the completeness of follow-up. Lancet 2002, 359:1309-1310.
16. Prezpiorka D., Weisdorf D., Martin P., et al. 1994 consensus conference on acute GVHD grading. Bone Marrow Transplant 1995, 15:825-828.
17. Sullivan K.M., Agura E., Anasetti C., et al. Chronic graft-versus-host disease and other late complications of bone marrow transplantation. Semin Hematol 1991, 28:250-259.
18. Ringdén O., Pavletic S.Z., Anasetti C., et al. The graft-versus-leukemia effect using matched unrelated donors is not superior to HLA-identical siblings for hematopoietic stem cell transplantation. Blood 2009, 113:3110-3118.
19. Giralt S., Ballen K., Rizzo D., et al. Reduced-intensity conditioning regimen workshop: defining the dose spectrum. Report of a workshop convened by the Center for International Bone Marrow Transplant Research. Biol Blood Marrow Transplant 2009, 15:367-369.
20. Bacigalupo A., Ballen K., Rizzo D., et al. Defining the intensity of conditioning regimens: working definitions. Biol Blood Marrow Transplant 2009, 15:1628-1633.
21. Cox D.R. Regression models and life tables (with discussion). J R Stat Soc, Ser B (Stat Method) 1972, 34:187-220.
22. Klein J.P. Modelling competing risks in cancer studies. Stat Med 2006, 25:1015-1034.
23. Commenges D., Andersen P.K. Score test of homogeneity for survival data. Lifetime Data Anal 1995, 1:145-156.
24. Ballen K.K., Spitzer T.R., Yeap B.Y., et al. Double unrelated reduced-intensity umbilical cord blood transplantation in adults. Biol Blood Marrow Transplant 2007, 13:82-89.
25. Majhail N.S., Omondi N.A., Denzen E., Murphy E.A., Rizzo J.D. Access to hematopoietic cell transplantation in the United States. Biol Blood Marrow Transplant 2010, 16:1070-1075.
26. Kollman C., Abella E., Baitty R.L., et al. Assessment of optimal size and composition of the U.S. National Registry of hematopoietic stem cell donors. Transplantation 2004, 78:89-95.
27. Barker J.N., Byam C.E., Kernan N.A., et al. Availability of cord blood extends allogeneic hematopoietic stem cell transplant access to racial and ethnic minorities. Biol Blood Marrow Transplant 2010, 16:1541-1548.
28. Ballen K.K., Hicks J., Dharan B., et al. Racial and ethnic composition of volunteer cord blood donors: comparison with volunteer unrelated marrow donors. Transfusion 2002, 42:1279-1284.
29. Mielcarek M., Gooley T., Martin P.J., et al. Effects of race on survival after stem cell transplantation. Biol Blood Marrow Transplant 2005, 11:231-239.
30. Baker K.S., Loberiza F.R., Yu H., et al. Outcome of ethnic minorities with acute or chronic leukemia treated with hematopoietic stem-cell transplantation in the United States. J Clin Oncol 2005, 23:7032-7042.
31. Lohmueller K.E., Indap A.R., Schmidt S., et al. Proportionally more deleterious genetic variation in European than in African populations. Nature 2008, 451:994-997.
32. Dickinson A.M., Harrold J.L., Cullup H. Haematopoietic stem cell transplantation: can our genes predict clinical outcome?. Expert Rev Mol Med 2007, 9:1-19.