Role of corticotropin-releasing hormone family peptides in androgen receptor and vitamin D receptor expression and translocation in human breast cancer MCF-7 cells

European Journal of Pharmacology

Volumn 684, Issue 1-3, 2012, Pages 27-35

  Jin, Lai ^a   Chen, Cheng ^a   Guo, Rui ^a   Wan, Rong ^a   Li, Shengnan ^a  

^a NANJING MEDICAL UNIVERSITY   (China)

Author keywords

Androgen receptor; CRH; MCF 7; Urocortin2; Vitamin D receptor

Indexed keywords

ANDROGEN RECEPTOR; ANTALARMIN; ANTISAUVAGINE 30; CORTICOTROPIN RELEASING FACTOR; CORTICOTROPIN RELEASING FACTOR RECEPTOR 1; CORTICOTROPIN RELEASING FACTOR RECEPTOR 2; HEAT SHOCK PROTEIN 27; MESSENGER RNA; UROCORTIN; UROCORTIN II; VITAMIN D RECEPTOR;

APOPTOSIS; ARTICLE; CANCER INHIBITION; CELL NUCLEUS; CELL STRAIN MCF 7; CONTROLLED STUDY; DRUG RECEPTOR BINDING; HORMONE RECEPTOR TRANSLOCATION; HORMONE RELEASE; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FAMILY; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; PROTEIN SYNTHESIS INHIBITION; RECEPTOR DOWN REGULATION; RECEPTOR UPREGULATION;

APOPTOSIS; BREAST NEOPLASMS; CELL LINE, TUMOR; CELL NUCLEUS; CORTICOTROPIN-RELEASING HORMONE; CYTOPLASM; GENE EXPRESSION REGULATION, NEOPLASTIC; HSP27 HEAT-SHOCK PROTEINS; HUMANS; PROTEIN TRANSPORT; RECEPTORS, ANDROGEN; RECEPTORS, CALCITRIOL; RECEPTORS, CORTICOTROPIN-RELEASING HORMONE; RNA STABILITY; RNA, MESSENGER; UP-REGULATION; UROCORTINS;

EID: 84860836657     PISSN: 00142999     EISSN: 18790712     Source Type: Journal    
DOI: 10.1016/j.ejphar.2012.03.034     Document Type: Article

References (51)

1. O. Aguilera, C. Pena, J.M. Garcia, M.J. Larriba, P. Ordonez-Moran, D. Navarro, A. Barbachano, I. Lopez de Silanes, E. Ballestar, M.F. Fraga, M. Esteller, C. Gamallo, F. Bonilla, J.M. Gonzalez-Sancho, and A. Munoz The Wnt antagonist DICKKOPF-1 gene is induced by 1alpha,25-dihydroxyvitamin D3 associated to the differentiation of human colon cancer cells Carcinogenesis 28 2007 1877 1884 (Pubitemid 47500598)
2. A. Androulidaki, E. Dermitzaki, M. Venihaki, E. Karagianni, O. Rassouli, E. Andreakou, C. Stournaras, A.N. Margioris, and C. Tsatsanis Corticotropin releasing factor promotes breast cancer cell motility and invasiveness Mol. Cancer 8 2009 30
3. M. Bajo, M.T. Cruz, G.R. Siggins, R. Messing, and M. Roberto Protein kinase C epsilon mediation of CRF- and ethanol-induced GABA release in central amygdala Proc. Natl. Acad. Sci. U. S. A. 105 2008 8410 8415 (Pubitemid 351904770)
4. B.Y. Bao, Y.C. Hu, H.J. Ting, and Y.F. Lee Androgen signaling is required for the vitamin D-mediated growth inhibition in human prostate cancer cells Oncogene 23 2004 3350 3360
5. A.M. Bao, D.F. Fischer, Y.H. Wu, E.M. Hol, R. Balesar, U.A. Unmehopa, J.N. Zhou, and D.F. Swaab A direct androgenic involvement in the expression of human corticotropin-releasing hormone Mol. Psychiatry 11 2006 567 576
6. R.S. Bhattacharyya, A.V. Krishnan, S. Swami, and D. Feldman Fulvestrant (ICI 182,780) down-regulates androgen receptor expression and diminishes androgenic responses in LNCaP human prostate cancer cells Mol. Cancer Ther. 5 2006 1539 1549 (Pubitemid 44070491)
7. S.N. Birrell, D.M. Roder, D.J. Horsfall, J.M. Bentel, and W.D. Tilley Medroxyprogesterone acetate therapy in advanced breast cancer: the predictive value of androgen receptor expression J. Clin. Oncol. 13 1995 1572 1577
8. M. Bower, K.W. Colston, R.C. Stein, A. Hedley, J.C. Gazet, H.T. Ford, and R.C. Combes Topical calcipotriol treatment in advanced breast cancer Lancet 337 1991 701 702
9. N. Chanplakorn, P. Chanplakorn, T. Suzuki, K. Ono, L. Wang, M.S. Chan, L. Wing, C.C. Yiu, L.W. Chow, and H. Sasano Increased 5alpha-reductase type 2 expression in human breast carcinoma following aromatase inhibitor therapy: the correlation with decreased tumor cell proliferation Horm. Cancer 2 2011 73 81
10. H. Chen, M. Hewison, and J.S. Adams Control of estradiol-directed gene transactivation by an intracellular estrogen-binding protein and an estrogen response element-binding protein Mol. Endocrinol. 22 2008 559 569 (Pubitemid 351397785)
11. D.R. Ciocca, L.A. Puy, L.C. Fasoli, O. Tello, J.C. Aznar, F.E. Gago, S.I. Papa, and R. Sonego Corticotropin-releasing hormone, luteinizing hormone-releasing hormone, growth hormone-releasing hormone, and somatostatin-like immunoreactivities in biopsies from breast cancer patients Breast Cancer Res. Treat. 15 1990 175 184 (Pubitemid 20369897)
12. C. Danielsson, I.S. Mathiasen, S.Y. James, S. Nayeri, C. Bretting, C.M. Hansen, K.W. Colston, and C. Carlberg Sensitive induction of apoptosis in breast cancer cells by a novel 1,25-dihydroxyvitamin D3 analogue shows relation to promoter selectivity J. Cell. Biochem. 66 1997 552 562 (Pubitemid 27377620)
13. F. De Amicis, J. Thirugnansampanthan, Y. Cui, J. Selever, A. Beyer, I. Parra, N.L. Weigel, M.H. Herynk, A. Tsimelzon, M.T. Lewis, G.C. Chamness, S.G. Hilsenbeck, S. Ando, and S.A. Fuqua Androgen receptor overexpression induces tamoxifen resistance in human breast cancer cells Breast Cancer Res. Treat. 121 2010 1 11
14. E. Dermitzaki, C. Tsatsanis, V. Minas, E. Chatzaki, I. Charalampopoulos, M. Venihaki, A. Androulidaki, M. Lambropoulou, J. Spiess, E. Michalodimitrakis, A. Gravanis, and A.N. Margioris Corticotropin-releasing factor (CRF) and the urocortins differentially regulate catecholamine secretion in human and rat adrenals, in a CRF receptor type-specific manner Endocrinology 148 2007 1524 1538 (Pubitemid 46457096)
15. C. Dimitrakakis, and C. Bondy Androgens and the breast Breast Cancer Res. 11 2009 212
16. R. Ghosh, K.L. Lipson, K.E. Sargent, A.M. Mercurio, J.S. Hunt, D. Ron, and F. Urano Transcriptional regulation of VEGF-A by the unfolded protein response pathway PLoS One 5 2010 e9575
17. G. Graziani, L. Tentori, A. Muzi, M. Vergati, G. Tringali, G. Pozzoli, and P. Navarra Evidence that corticotropin-releasing hormone inhibits cell growth of human breast cancer cells via the activation of CRH-R1 receptor subtype Mol. Cell. Endocrinol. 264 2007 44 49 (Pubitemid 46097300)
18. S. Hassan, M.H. Biswas, C. Zhang, C. Du, and K.C. Balaji Heat shock protein 27 mediates repression of androgen receptor function by protein kinase D1 in prostate cancer cells Oncogene 28 2009 4386 4396
19. R.L. Hauger, V. Risbrough, R.H. Oakley, J.A. Olivares-Reyes, and F.M. Dautzenberg Role of CRF receptor signaling in stress vulnerability, anxiety, and depression Ann. N. Y. Acad. Sci. 1179 2009 120 143
20. T. Ikezoe, S. Gery, D. Yin, J. O'Kelly, L. Binderup, N. Lemp, H. Taguchi, and H.P. Koeffler CCAAT/enhancer-binding protein delta: a molecular target of 1,25-dihydroxyvitamin D3 in androgen-responsive prostate cancer LNCaP cells Cancer Res. 65 2005 4762 4768 (Pubitemid 40740813)
21. L. Jin, Q. Zhang, R. Guo, L. Wang, J. Wang, R. Wan, R. Zhang, Y. Xu, and S. Li Different effects of corticotrophin-releasing hormone and urocortin 2 on apoptosis of prostate cancer cells in vitro J. Mol. Endocrinol. 47 2011 219 227
22. K. Kageyama, K. Hanada, and T. Suda Differential regulation of urocortins1-3 mRNA in human umbilical vein endothelial cells Regul. Pept. 155 2009 131 138
23. A. Kaprara, K. Pazaitou-Panayiotou, M.C. Chemonidou, T.C. Constantinidis, M. Lambropoulou, M. Koffa, A. Kiziridou, S. Kakolyris, A. Kortsaris, and E. Chatzaki Distinct distribution of corticotropin releasing factor receptors in human breast cancer Neuropeptides 44 2010 355 361
24. J.A. Kemppainen, M.V. Lane, M. Sar, and E.M. Wilson Androgen receptor phosphorylation, turnover, nuclear transport, and transcriptional activation. Specificity for steroids and antihormones J. Biol. Chem. 267 1992 968 974
25. A.V. Krishnan, S. Swami, and D. Feldman Vitamin D and breast cancer: inhibition of estrogen synthesis and signaling J. Steroid Biochem. Mol. Biol. 121 2010 343 348
26. F. Labrie, V. Luu-The, C. Labrie, A. Belanger, J. Simard, S.X. Lin, and G. Pelletier Endocrine and intracrine sources of androgens in women: inhibition of breast cancer and other roles of androgens and their precursor dehydroepiandrosterone Endocr. Rev. 24 2003 152 182 (Pubitemid 36515283)
27. J. Licinio, P.W. Gold, and M.L. Wong A molecular mechanism for stress-induced alterations in susceptibility to disease Lancet 346 1995 104 106
28. L.F. Macedo, Z. Guo, S.L. Tilghman, G.J. Sabnis, Y. Qiu, and A. Brodie Role of androgens on MCF-7 breast cancer cell growth and on the inhibitory effect of letrozole Cancer Res. 66 2006 7775 7782 (Pubitemid 44289238)
29. E.T. Maizels, C.A. Peters, M. Kline, R.E. Cutler Jr., M. Shanmugam, and M. Hunzicker-Dunn Heat-shock protein-25/27 phosphorylation by the delta isoform of protein kinase C Biochem. J. 332 Pt 3 1998 703 712 (Pubitemid 28306696)
30. R.N. Margolis, and S. Christakos The nuclear receptor superfamily of steroid hormones and vitamin D gene regulation. An update Ann. N. Y. Acad. Sci. 1192 2010 208 214
31. J. Mlynarczyk-Liszka, B. Maksymiuk, D. Ponikiewska, S. Krzyzowska-Gruca, D. Lange, Z. Krawczyk, and E. Malusecka HSP27 diagnostic utility in the fine needle aspirate of breast. Correlation with progesterone and estrogen receptors Neoplasma 56 2009 357 360
32. F. Moinfar, M. Okcu, O. Tsybrovskyy, P. Regitnig, S.F. Lax, W. Weybora, M. Ratschek, F.A. Tavassoli, and H. Denk Androgen receptors frequently are expressed in breast carcinomas: potential relevance to new therapeutic strategies Cancer 98 2003 703 711 (Pubitemid 36959265)
33. Y. Muramatsu, N. Sugino, T. Suzuki, K. Totsune, K. Takahashi, A. Tashiro, M. Hongo, Y. Oki, and H. Sasano Urocortin and corticotropin-releasing factor receptor expression in normal cycling human ovaries J. Clin. Endocrinol. Metab. 86 2001 1362 1369 (Pubitemid 32323029)
34. C.J. Narvaez, and J. Welsh Differential effects of 1,25-dihydroxyvitamin D3 and tetradecanoylphorbol acetate on cell cycle and apoptosis of MCF-7 cells and a vitamin D3-resistant variant Endocrinology 138 1997 4690 4698 (Pubitemid 27460904)
35. M.S. Nayak, J.M. Yang, and W.N. Hait Effect of a single nucleotide polymorphism in the murine double minute 2 promoter (SNP309) on the sensitivity to topoisomerase II-targeting drugs Cancer Res. 67 2007 5831 5839 (Pubitemid 46985017)
36. P.A. O'Neill, A.M. Shaaban, C.R. West, A. Dodson, C. Jarvis, P. Moore, M.P. Davies, D.R. Sibson, and C.S. Foster Increased risk of malignant progression in benign proliferating breast lesions defined by expression of heat shock protein 27 Br. J. Cancer 90 2004 182 188 (Pubitemid 38174959)
37. M. Paliouras, and E.P. Diamandis Androgens act synergistically to enhance estrogen-induced upregulation of human tissue kallikreins 10, 11, and 14 in breast cancer cells via a membrane bound androgen receptor Mol. Oncol. 1 2008 413 424
38. K.L. Parham, S. Zervou, E. Karteris, R.D. Catalano, R.W. Old, and E.W. Hillhouse Promoter analysis of human corticotropin-releasing factor (CRF) type 1 receptor and regulation by CRF and urocortin Endocrinology 145 2004 3971 3983 (Pubitemid 39037586)
39. M.H. Perrin, and W.W. Vale Corticotropin releasing factor receptors and their ligand family Ann. N. Y. Acad. Sci. 885 1999 312 328
40. A.A. Peters, G. Buchanan, C. Ricciardelli, T. Bianco-Miotto, M.M. Centenera, J.M. Harris, S. Jindal, D. Segara, L. Jia, N.L. Moore, S.M. Henshall, S.N. Birrell, G.A. Coetzee, R.L. Sutherland, L.M. Butler, and W.D. Tilley Androgen receptor inhibits estrogen receptor-alpha activity and is prognostic in breast cancer Cancer Res. 69 2009 6131 6140
41. M.J. Rane, P.Y. Coxon, D.W. Powell, R. Webster, J.B. Klein, W. Pierce, P. Ping, and K.R. McLeish p38 Kinase-dependent MAPKAPK-2 activation functions as 3-phosphoinositide-dependent kinase-2 for Akt in human neutrophils J. Biol. Chem. 276 2001 3517 3523
42. M.J. Rane, Y. Pan, S. Singh, D.W. Powell, R. Wu, T. Cummins, Q. Chen, K.R. McLeish, and J.B. Klein Heat shock protein 27 controls apoptosis by regulating Akt activation J. Biol. Chem. 278 2003 27828 27835 (Pubitemid 36899975)
43. M. Razandi, A. Pedram, and E.R. Levin Heat shock protein 27 is required for sex steroid receptor trafficking to and functioning at the plasma membrane Mol. Cell. Biol. 30 2010 3249 3261
44. T.A. Reinhardt, and R.L. Horst Phorbol 12-myristate 13-acetate and 1,25-dihydroxyvitamin D3 regulate 1,25-dihydroxyvitamin D3 receptors synergistically in rat osteosarcoma cells Mol. Cell. Endocrinol. 101 1994 159 165 (Pubitemid 24132786)
45. X. Sun, J.M. Fontaine, I. Bartl, B. Behnam, M.J. Welsh, and R. Benndorf Induction of Hsp22 (HspB8) by estrogen and the metalloestrogen cadmium in estrogen receptor-positive breast cancer cells Cell Stress Chaperones 12 2007 307 319
46. M.A. Tessel, N.L. Krett, and S.T. Rosen Steroid receptor and microRNA regulation in cancer Curr. Opin. Oncol. 22 2010 592 597
47. J. Vaughan, C. Donaldson, J. Bittencourt, M.H. Perrin, K. Lewis, S. Sutton, R. Chan, A.V. Turnbull, D. Lovejoy, and C. Rivier Urocortin, a mammalian neuropeptide related to fish urotensin I and to corticotropin-releasing factor Nature 378 1995 287 292
48. V. Viau, A. Chu, L. Soriano, and M.F. Dallman Independent and overlapping effects of corticosterone and testosterone on corticotropin-releasing hormone and arginine vasopressin mRNA expression in the paraventricular nucleus of the hypothalamus and stress-induced adrenocorticotropic hormone release J. Neurosci. 19 1999 6684 6693 (Pubitemid 29347468)
49. S. Yeh, Y.C. Hu, P.H. Wang, C. Xie, Q. Xu, M.Y. Tsai, Z. Dong, R.S. Wang, T.H. Lee, and C. Chang Abnormal mammary gland development and growth retardation in female mice and MCF7 breast cancer cells lacking androgen receptor J. Exp. Med. 198 2003 1899 1908 (Pubitemid 38032122)
50. H.Y. Zhi, S.W. Hou, R.S. Li, Z. Basir, Q. Xiang, A. Szabo, and G. Chen PTPH1 cooperates with vitamin D receptor to stimulate breast cancer growth through their mutual stabilization Oncogene 30 2011 1706 1715
51. A. Zoubeidi, A. Zardan, E. Beraldi, L. Fazli, R. Sowery, P. Rennie, C. Nelson, and M. Gleave Cooperative interactions between androgen receptor (AR) and heat-shock protein 27 facilitate AR transcriptional activity Cancer Res. 67 2007 10455 10465 (Pubitemid 350070821)