Findings that shed new light on the possible pathogenesis of a disease or an adverse effect: Acute life-threatening methaemoglobinaemia following ingestion of chloroquine

BMJ Case Reports

Volumn , Issue , 2012, Pages

  Rizvi, Imran ^a   Zaman, Shamsuz ^a   Zaidi, Noorin ^a   Mohammed Asif, S ^a   Abdali, Nasar ^a  

^a ALIGARH MUSLIM UNIVERSITY   (India)

Author keywords

[No Author keywords available]

Indexed keywords

CHLOROQUINE; METHEMOGLOBIN; METHYLENE BLUE; OXYGEN;

ACUTE DISEASE; ADULT; ARTERIAL BLOOD; ARTERIAL OXYGEN TENSION; ARTICLE; BLOOD GAS ANALYSIS; CASE REPORT; CYANOSIS; DRUG INTOXICATION; DRUG OVERDOSE; DRUG TREATMENT FAILURE; FOLLOW UP; HUMAN; MALE; METHEMOGLOBINEMIA; OXYGEN SATURATION; PRIORITY JOURNAL; PULSE OXIMETRY;

EID: 84860789517     PISSN: None     EISSN: 1757790X     Source Type: Journal    
DOI: 10.1136/bcr.12.2011.5383     Document Type: Article

References (13)

1. Curry A, Carlton M. Hemotologic consequences of poisoning. In: Haddad LM, Shannon MW, Winchester J F, eds. Clinical Management of Poisoning and Overdose. Third Edition. Philadelphia: WB Saunders 1998:223-35.
2. Jaffé ER. Methaemoglobinaemia. Clin Haematol 1981;10:99-122.
3. Beutler E. Methemoglobinemia and other causes of cyanosis. In: Lichtman MA, Beutler E, Kipps TJ, Seligsohn U, Kaushansky K, eds. Williams Hematology. Seventh Edition. New york: McGraw-Hill 2005:701-6.
4. Bodansky O. Methemoglobinemia and methemoglobin-producing compounds. Pharmacol Rev 1951;3:144-96.
5. Smith RP, Olson MV. Drug-induced methemoglobinemia. Semin Hematol 1973;10:253-68.
6. Cohen RJ, Sachs JR, Wicker DJ, et al. Methemoglobinemia provoked by malarial chemoprophylaxis in Vietnam. N Engl J Med 1968;279:1127-31.
7. Carmona-Fonseca J, Alvarez G, Maestre A. Methemoglobinemia and adverse events in Plasmodium vivax malaria patients associated with high doses of primaquine treatment. Am J Trop Med Hyg 2009;80:188-93.
8. Sankar J, Gupta A, Pathak S, et al. Death in an adolescent girl with methemoglobinemia and malaria. J Trop Pediatr 2011 (In Press).
9. Sharma N, Varma S. Unusual life-threatening adverse drug effects with chloroquine in a young girl. J Postgrad Med 2003;49:187. (Pubitemid 36950091)
10. Watcha MF, Connor MT, Hing AV. Pulse oximetry in methemoglobinemia. Am J Dis Child 1989;143:845-7. (Pubitemid 19172106)
11. Howland MA. Antidotes in depth: methylene blue. In: Goldfrank LR, ed. Goldfrank's Toxocologic Emergencies. Fifth Edition. Norwalk: Appleton and Lange 1994:1179-80.
12. Blanc PD. Methemoglobinemia. In: Olson KR, ed. Poisoning and Drug Overdose. Third Edition. Norwalk: Appleton and Lange 1999:220-2.
13. Roigas H, Zoellner E, Jacobasch G, et al. [Regulatory factors in methylene blue catalysis in erythrocytes]. Eur J Biochem 1970;12:24-30.