Mitochondrial changes within axons in multiple sclerosis: An update

Current Opinion in Neurology

Volumn 25, Issue 3, 2012, Pages 221-230

  Campbell, Graham R ^a   Ohno, Nobuhiko ^b   Turnbull, Doug M ^c   Mahad, Don J ^a  

^a UNIVERSITY OF EDINBURGH   (United Kingdom)

^b LERNER RESEARCH INSTITUTE   (United States)

^c NEWCASTLE UNIVERSITY   (United Kingdom)

Author keywords

Axon; Demyelination and remyelination; Mitochondria; Multiple sclerosis

Indexed keywords

ADENOSINE TRIPHOSPHATASE (POTASSIUM SODIUM); CALCIUM CHANNEL; CYTOCHROME C OXIDASE; DOCKING PROTEIN; MICRORNA; MITOCHONDRIAL DNA; MITOFUSIN 1; MITOFUSIN 2; MYELIN; POTASSIUM CHANNEL KV1.1; POTASSIUM CHANNEL KV1.2; PROTON TRANSPORTING ADENOSINE TRIPHOSPHATE SYNTHASE; REACTIVE NITROGEN SPECIES; REACTIVE OXYGEN METABOLITE; SODIUM CALCIUM EXCHANGE PROTEIN; SODIUM CHANNEL; SYNTAPHILIN; UNCLASSIFIED DRUG;

AXOPLASM; BIOGENESIS; CELL SIZE; CELLULAR DISTRIBUTION; CENTRAL NERVOUS SYSTEM; CEREBELLUM; CYTOPLASM; DEMYELINATION; ELECTRIC ACTIVITY; ENZYME ACTIVITY; EXTRACELLULAR CALCIUM; HUMAN; IN VITRO STUDY; IN VIVO STUDY; INFLAMMATION; ION TRANSPORT; MICROGLIA; MITOCHONDRION; MULTIPLE SCLEROSIS; MYELIN SHEATH; MYELINATION; NERVE ENDING; NERVE FIBER; NONHUMAN; OLIGODENDROGLIA; OXYGEN CONSUMPTION; PATHOGENESIS; PERIPHERAL NERVOUS SYSTEM; PROTEIN SYNTHESIS; REMYELINIZATION; REVIEW; SCANNING ELECTRON MICROSCOPY; SCHWANN CELL; SPINAL GANGLION;

ANIMALS; AXONS; BIOGENESIS; CENTRAL NERVOUS SYSTEM; HUMANS; MITOCHONDRIA; MULTIPLE SCLEROSIS; MYELIN SHEATH;

EID: 84860774312     PISSN: 13507540     EISSN: 14736551     Source Type: Journal    
DOI: 10.1097/WCO.0b013e3283533a25     Document Type: Review

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