Increased vascular inflammation in early menopausal women is associated with hot flush severity

Journal of Clinical Endocrinology and Metabolism

Volumn 97, Issue 5, 2012, Pages

  Bechlioulis, Aris ^a   Naka, Katerina K ^a,b   Kalantaridou, Sophia N ^b   Kaponis, Apostolos ^b   Papanikolaou, Odysseas ^b   Vezyraki, Patra ^b   Kolettis, Theofilos M ^b   Vlahos, Antonis P ^b   Gartzonika, Konstantina ^b   Mavridis, Anestis ^b   Michalis, Lampros K ^a,b  

^a UNIVERSITY OF IOANNINA   (Greece)

^b UNIVERSITY HOSPITAL OF IOANNINA   (Greece)

Author keywords

[No Author keywords available]

Indexed keywords

C REACTIVE PROTEIN; CD40 LIGAND; PADGEM PROTEIN;

ADULT; ARTICLE; CONTROLLED STUDY; CROSS-SECTIONAL STUDY; DISEASE ASSOCIATION; DISEASE SEVERITY; EARLY MENOPAUSE; FEMALE; HOT FLUSH; HUMAN; MAJOR CLINICAL STUDY; PREMENOPAUSE; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; VASCULITIS;

ADULT; C-REACTIVE PROTEIN; CD40 LIGAND; CROSS-SECTIONAL STUDIES; FEMALE; HOT FLASHES; HUMANS; INFLAMMATION; MENOPAUSE; MIDDLE AGED; P-SELECTIN; SEVERITY OF ILLNESS INDEX;

EID: 84860744748     PISSN: 0021972X     EISSN: 19457197     Source Type: Journal    
DOI: 10.1210/jc.2011-3151     Document Type: Article

References (24)

1. Collins P, Rosano G, Casey C, Daly C, Gambacciani M, Hadji P, Kaaja R, Mikkola T, Palacios S, Preston R, Simon T, Stevenson J, Stramba-Badiale M 2007 Management of cardiovascular risk in the peri-menopausal woman: a consensus statement of European cardiologists and gynaecologists. Eur Heart J 28:2028-2040
2. Bechlioulis A, Kalantaridou SN, Naka KK, Chatzikyriakidou A, Calis KA, Makrigiannakis A, Papanikolaou O, Kaponis A, Katsouras C, Georgiou I, Chrousos GP, Michalis LK 2010 Endothelial function, but not carotid intima-media thickness, is affected early in menopause and is associated with severity of hot flushes. J Clin Endocrinol Metab 95:1199-1206
3. Oger E, Alhenc-Gelas M, Plu-Bureau G, Mennen L, Cambillau M, Guize L, Pujol Y, Scarabin P 2001 Association of circulating cellular adhesion molecules with menopausal status and hormone replacement therapy. Time-dependent change in transdermal, but not oral estrogen users. Thromb Res 101:35-43
4. Blankenberg S, Barbaux S, Tiret L 2003 Adhesion molecules and atherosclerosis. Atherosclerosis 170:191-203
5. Szmitko PE, Wang CH, Weisel RD, de Almeida JR, Anderson TJ, Verma S 2003 New markers of inflammation and endothelial cell activation: Part I. Circulation 108:1917-1923
6. Ridker PM, Buring JE, Rifai N 2001 Soluble P-selectin and the risk of future cardiovascular events. Circulation 103:491-495
7. Schönbeck U, Varo N, Libby P, Buring J, Ridker PM 2001 Soluble CD40L and cardiovascular risk in women. Circulation 104:2266-2268
8. Ridker PM, Hennekens CH, Buring JE, Rifai N 2000 C-reactive protein and other markers of inflammation in the prediction of cardiovascular disease in women. N Engl J Med 342:836-843
9. Matthews KA, Crawford SL, Chae CU, Everson-Rose SA, Sowers MF, Sternfeld B, Sutton-Tyrrell K 2009 Are changes in cardiovascular disease risk factors in midlife women due to chronological aging or to the menopausal transition? J Am Coll Cardiol 54:2366-2373
10. Thurston RC, Sutton-Tyrrell K, Everson-Rose SA, Hess R, Matthews KA 2008 Hot flashes and subclinical cardiovascular disease: findings from the Study of Women's Health Across the Nation Heart Study. Circulation 118:1234-1240
11. Thurston RC, Sutton-Tyrrell K, Everson-Rose SA, Hess R, Powell LH, Matthews KA 2011 Hot flashes and carotid intima media thickness among midlife women. Menopause 18:352-358
12. Gast GC, Pop VJ, Samsioe GN, Grobbee DE, Nilsson PM, Keyzer JJ, Wijnands-van Gent CJ, van der Schouw YT 2011 Vasomotor menopausal symptoms are associated with increased risk of coronary heart disease. Menopause 18:146-151
13. Yasui T, Uemura H, Tomita J, Miyatani Y, Yamada M, Kuwahara A, Matsuzaki T, Maegawa M, Tsuchiya N, Yuzurihara M, Takeda S, Irahara M 2006 Association of interleukin-8 with hot flashes in premenopausal, perimenopausal, and postmenopausal women and bilateral oophorectomized women. J Clin Endocrinol Metab 91:4805-4808
14. Thurston RC, El Khoudary SR, Sutton-Tyrrell K, Crandall CJ, Gold E, Sternfeld B, Selzer F, Matthews KA 2011 Are vasomotor symptoms associated with alterations in hemostatic and inflammatory markers? Findings from the Study of Women's Health Across the Nation. Menopause 18:1044-1051
15. Shifren JL, Rifai N, Desindes S, McIlwain M, Doros G, Mazer NA 2008 A comparison of the short-term effects of oral conjugated equine estrogens versus transdermal estradiol on C-reactive protein, other serum markers of inflammation, and other hepatic proteins in naturally menopausal women. J Clin Endocrinol Metab 93:1702-1710
16. Oviedo PJ, Hermenegildo C, Sobrino A, Tarín JJ, Cano A 2008 Therapeutic dosages of oral or transdermal estradiol did not modify sCD40L levels in postmenopausal women. Gynecol Endocrinol 24:354-357
17. Bechlioulis A, Naka KK, Kalantaridou SN, Chatzikyriakidou A, Papanikolaou O, Kaponis A, Vakalis K, Vezyraki P, Gartzonika K, Mavridis A, Georgiou I, Michalis LK 23 January 2012 Short-term hormone therapy improves sCD40L and endothelial function in early menopausal women: potential role of estrogen receptor polymorphisms. Maturitas 101016/jmaturitas201201001
18. Sassarini J, Fox H, Ferrell W, Sattar N, Lumsden MA 2011 Vascular function and cardiovascular risk factors in women with severe flushing. Clin Endocrinol (Oxf) 74:97-103
19. De Pergola G, Pannacciulli N, Coviello M, Scarangella A, Di Roma P, Caringella M, Venneri MT, Quaranta M, Giorgino R 2008 sP-selectin plasma levels in obesity: association with insulin resistance and related metabolic and prothrombotic factors. Nutr Metab Cardiovasc Dis 18:227-232
20. Gentile M, Panico S, Rubba F, Mattiello A, Chiodini P, Jossa F, Marotta G, Pauciullo P, Rubba P 2010 Obesity, overweight, and weight gain over adult life are main determinants of elevated hs-CRP in a cohort of Mediterranean women. Eur J Clin Nutr 64:873-878
21. Bansal S, Buring JE, Rifai N, Mora S, Sacks FM, Ridker PM 2007 Fasting compared with nonfasting triglycerides and risk of cardiovascular events in women. JAMA 298:309-316
22. Savoia C, Schiffrin EL 2006 Inflammation in hypertension. Curr Opin Nephrol Hypertens 15:152-158
23. Wildman RP, Colvin AB, Powell LH, Matthews KA, Everson-Rose SA, Hollenberg S, Johnston JM, Sutton-Tyrrell K 2008 Associations of endogenous sex hormones with the vasculature in menopausal women: the Study of Women's Health Across the Nation (SWAN). Menopause 15:414-421
24. Mulvagh SL, Behrenbeck T, Lahr BA, Bailey KR, Zais TG, Araoz PA, Miller VM 2010 Endothelial function and cardiovascular risk stratification in menopausal women. Climacteric 13:45-54