-
1
-
-
0015150080
-
Report of the Committee on Hodgkin's Disease Staging Classification
-
Carbone, P.P., Kaplan, H.S., Musshoff, K., Smithers, D.W., Tubiana, M. Report of the Committee on Hodgkin's Disease Staging Classification. Cancer Res 1971, 31(11): 1860-1.
-
(1971)
Cancer Res
, vol.31
, Issue.11
, pp. 1860-1861
-
-
Carbone, P.P.1
Kaplan, H.S.2
Musshoff, K.3
Smithers, D.W.4
Tubiana, M.5
-
2
-
-
0024422603
-
Report of a committee convened to discuss the evaluation and staging of patients with Hodgkin's disease: Cotswolds meeting
-
Lister, T.A., Crowther, D., Sutcliffe, S.B. et al. Report of a committee convened to discuss the evaluation and staging of patients with Hodgkin's disease: Cotswolds meeting. J Clin Oncol 1989, 7(11): 1630-6. (Pubitemid 19272832)
-
(1989)
Journal of Clinical Oncology
, vol.7
, Issue.11
, pp. 1630-1636
-
-
Lister, T.A.1
Crowther, D.2
Sutcliffe, S.B.3
Glatstein, E.4
Canellos, G.P.5
Young, R.C.6
Rosenberg, S.A.7
Coltman, C.A.8
Tubiana, M.9
-
3
-
-
0001785009
-
Hodgkin on some Morbid Appearances of the Absorbent Glands and Spleen
-
Hodgkin On some Morbid Appearances of the Absorbent Glands and Spleen. Med Chir Trans 1832, 17: 68-114.
-
(1832)
Med Chir Trans
, vol.17
, pp. 68-114
-
-
-
4
-
-
0001329373
-
On the pathological changes in Hodgkin's disease, with special reference to its relation to tuberculosis
-
Reed, D. On the pathological changes in Hodgkin's disease, with special reference to its relation to tuberculosis. Johns Hopkins Hosp Rep 1902, 10: 133-9.
-
(1902)
Johns Hopkins Hosp Rep
, vol.10
, pp. 133-139
-
-
Reed, D.1
-
5
-
-
27244442106
-
State-of-the-art therapeutics: Hodgkin's lymphoma
-
DOI 10.1200/JCO.2005.05.016
-
Connors, J.M. State-of-the-art therapeutics: Hodgkin's lymphoma. J Clin Oncol 2005, 23(26): 6400-8. (Pubitemid 46222240)
-
(2005)
Journal of Clinical Oncology
, vol.23
, Issue.26
, pp. 6400-6408
-
-
Connors, J.M.1
-
6
-
-
0026439199
-
Chemotherapy of advanced Hodgkin's disease with MOPP, ABVD, or MOPP alternating with ABVD
-
Canellos, G.P., Anderson, J.R., Propert, K.J. et al. Chemotherapy of advanced Hodgkin's disease with MOPP, ABVD, or MOPP alternating with ABVD. N Engl J Med 1992, 327(21): 1478-84.
-
(1992)
N Engl J Med
, vol.327
, Issue.21
, pp. 1478-1484
-
-
Canellos, G.P.1
Anderson, J.R.2
Propert, K.J.3
-
7
-
-
84855789037
-
Brentuximab vedotin (SGN-35), an antibody-drug conjugate for the treatment of CD30-positive malignancies
-
Gualberto, A. Brentuximab vedotin (SGN-35), an antibody-drug conjugate for the treatment of CD30-positive malignancies. Expert Opin Investig Drugs 2012, 21(2): 205-16.
-
(2012)
Expert Opin Investig Drugs
, vol.21
, Issue.2
, pp. 205-216
-
-
Gualberto, A.1
-
8
-
-
8644228628
-
Elevated serum-soluble interleukin-2 receptor levels in patients with anaplastic large cell lymphoma
-
DOI 10.1182/blood-2003-11-3922
-
Janik, J.E., Morris, J.C., Pittaluga, S. et al. Elevated serum-soluble interleukin-2 receptor levels in patients with anaplastic large cell lymphoma. Blood 2004, 104(10): 3355-7. (Pubitemid 39507157)
-
(2004)
Blood
, vol.104
, Issue.10
, pp. 3355-3357
-
-
Janik, J.E.1
Morris, J.C.2
Pittaluga, S.3
McDonald, K.4
Raffeld, M.5
Jaffe, E.S.6
Grant, N.7
Gutierrez, M.8
Waldmann, T.A.9
Wilson, W.H.10
-
9
-
-
0030822414
-
Primary anaplastic large-cell lymphoma in adults: Clinical presentation, immunophenotype, and outcome
-
Tilly, H., Gaulard, P., Lepage, E. et al. Primary anaplastic large-cell lymphoma in adults: clinical presentation, immunophenotype, and outcome. Blood 1997, 90(9): 3727-34. (Pubitemid 27473445)
-
(1997)
Blood
, vol.90
, Issue.9
, pp. 3727-3734
-
-
Tilly, H.1
Gaulard, P.2
Lepage, E.3
Dumontet, C.4
Diebold, J.5
Plantier, I.6
Berger, F.7
Symann, M.8
Petrella, T.9
Lederlin, P.10
Briere, J.11
-
10
-
-
67651171726
-
Prognosis and primary therapy in peripheral Tcell lymphomas
-
Savage, K.J. Prognosis and primary therapy in peripheral Tcell lymphomas. Hematology Am Soc Hematol Educ Program 2008: 280-8.
-
(2008)
Hematology Am Soc Hematol Educ Program
, pp. 280-288
-
-
Savage, K.J.1
-
11
-
-
47049084821
-
ALK- anaplastic large-cell lymphoma is clinically and immunophenotypically different from both ALK+ ALCL and peripheral T-cell lymphoma, not otherwise specified: Report from the International Peripheral T-Cell Lymphoma Project
-
Savage, K.J., Harris, N.L., Vose, J.M. et al. ALK- anaplastic large-cell lymphoma is clinically and immunophenotypically different from both ALK+ ALCL and peripheral T-cell lymphoma, not otherwise specified: report from the International Peripheral T-Cell Lymphoma Project. Blood 2008, 111(12): 5496-504.
-
(2008)
Blood
, vol.111
, Issue.12
, pp. 5496-5504
-
-
Savage, K.J.1
Harris, N.L.2
Vose, J.M.3
-
12
-
-
0019981972
-
Production of a monoclonal antibody specific for Hodgkin and Sternberg-Reed cells of Hodgkin's disease and a subset of normal lymphoid cells
-
DOI 10.1038/299065a0
-
Schwab, U., Stein, H., Gerdes, J., Lemke, H., Kirchner, H., Schaadt, M., Diehl, V. Production of a monoclonal antibody specific for Hodgkin and Sternberg-Reed cells of Hodgkin's disease and a subset of normal lymphoid cells. Nature 1982, 299(5878): 65-7. (Pubitemid 12049770)
-
(1982)
Nature
, vol.299
, Issue.5878
, pp. 65-67
-
-
Schwab, U.1
Stein, H.2
Gerdes, J.3
-
13
-
-
0343238919
-
Expression of the CD30 antigen in non-lymphoid tissues and cells
-
DOI 10.1002/(SICI)1096-9896(200004)190:5<613::AID-PATH559>3.0.CO;2- 0
-
Durkop, H., Foss, H.D., Eitelbach, F., Anagnostopoulos, I., Latza, U., Pileri, S., Stein, H. Expression of the CD30 antigen in non-lymphoid tissues and cells. J Pathol 2000, 190(5): 613-8. (Pubitemid 30164492)
-
(2000)
Journal of Pathology
, vol.190
, Issue.5
, pp. 613-618
-
-
Durkop, H.1
Foss, H.-D.2
Eitelbach, F.3
Anagnostopoulos, B.4
Latza, U.5
Pilen, S.6
Stein, H.7
-
14
-
-
0142026056
-
Emerging applications of the tumor necrosis factor family of ligands and receptors in cancer therapy
-
DOI 10.1200/JCO.2003.09.037
-
Younes, A., Kadin, M.E. Emerging applications of the tumor necrosis factor family of ligands and receptors in cancer therapy. J Clin Oncol 2003, 21(18): 3526-34. (Pubitemid 46594087)
-
(2003)
Journal of Clinical Oncology
, vol.21
, Issue.18
, pp. 3526-3534
-
-
Younes, A.1
Kadin, M.E.2
-
15
-
-
0242607588
-
Expression of B-Cell Markers in Classical Hodgkin Lymphoma: A Tissue Microarray Analysis of 330 Cases
-
DOI 10.1097/01.MP.0000093627.51090.3F
-
Tzankov, A., Zimpfer, A., Pehrs, A.C. et al. Expression of Bcell markers in classical hodgkin lymphoma: a tissue microarray analysis of 330 cases. Mod Pathol 2003, 16(11): 1141-7. (Pubitemid 37414209)
-
(2003)
Modern Pathology
, vol.16
, Issue.11
, pp. 1141-1147
-
-
Tzankov, A.1
Zimpfer, A.2
Pehrs, A.-C.3
Lugli, A.4
Went, P.5
Maurer, R.6
Pileri, S.7
Dirnhofer, S.8
-
16
-
-
0037390128
-
Prognostic significance of CD20 expression in classical Hodgkin lymphoma: A clinicopathological study of 119 cases
-
Tzankov, A., Krugmann, J., Fend, F., Fischhofer, M., Greil, R., Dirnhofer, S. Prognostic significance of CD20 expression in classical Hodgkin lymphoma: a clinicopathological study of 119 cases. Clin Cancer Res 2003, 9(4): 1381-6. (Pubitemid 36418390)
-
(2003)
Clinical Cancer Research
, vol.9
, Issue.4
, pp. 1381-1386
-
-
Tzankov, A.1
Krugmann, J.2
Fend, F.3
Fischhofer, M.4
Greil, R.5
Dirnhofer, S.6
-
17
-
-
0027162651
-
CD30 antigen, a marker for Hodgkin's lymphoma, is a receptor whose ligand defines an emerging family of cytokines with homology to TNF
-
DOI 10.1016/0092-8674(93)90361-S
-
Smith, C.A., Gruss, H.J., Davis, T. et al. CD30 antigen, a marker for Hodgkin's lymphoma, is a receptor whose ligand defines an emerging family of cytokines with homology to TNF. Cell 1993, 73(7): 1349-60. (Pubitemid 23201148)
-
(1993)
Cell
, vol.73
, Issue.7
, pp. 1349-1360
-
-
Smith, C.A.1
Gruss, H.-J.2
Davis, T.3
Anderson, D.4
Farrah, T.5
Baker, E.6
Sutherland, G.R.7
Brannan, C.I.8
Copeland, N.G.9
Jenkins, N.A.10
Grabstein, K.H.11
Gliniak, B.12
McAlister, I.B.13
Fanslow, W.14
Alderson, M.15
Falk, B.16
Gimpel, S.17
Gillis, S.18
Din, W.S.19
-
18
-
-
0032751560
-
CD30/CD30 ligand and CD40/CD40 ligand in malignant lymphoid disorders
-
Younes, A., Carbone, A. CD30/CD30 ligand and CD40/CD40 ligand in malignant lymphoid disorders. Int J Biol Markers 1999, 14(3): 135-43. (Pubitemid 29495742)
-
(1999)
International Journal of Biological Markers
, vol.14
, Issue.3
, pp. 135-143
-
-
Younes, A.1
Carbone, A.2
-
19
-
-
80054111050
-
CD30-targeted antibody therapy
-
Younes, A. CD30-targeted antibody therapy. Curr Opin Oncol 2011, 23(6): 587-93.
-
(2011)
Curr Opin Oncol
, vol.23
, Issue.6
, pp. 587-593
-
-
Younes, A.1
-
20
-
-
39549084701
-
CD30-induced signaling is absent in Hodgkin's cells but present in anaplastic large cell lymphoma cells
-
DOI 10.2353/ajpath.2008.070858
-
Hirsch, B., Hummel, M., Bentink, S. et al. CD30-induced signaling is absent in Hodgkin's cells but present in anaplastic large cell lymphoma cells. Am J Pathol 2008, 172(2): 510-20. (Pubitemid 351282036)
-
(2008)
American Journal of Pathology
, vol.172
, Issue.2
, pp. 510-520
-
-
Hirsch, B.1
Hummel, M.2
Bentink, S.3
Fouladi, F.4
Spang, R.5
Zollinger, R.6
Stein, H.7
Durkop, H.8
-
21
-
-
0034672237
-
Differential effects of CD30 activation in anaplastic large cell lymphoma and Hodgkin disease cells
-
Mir, S.S., Richter, B.W., Duckett, C.S. Differential effects of CD30 activation in anaplastic large cell lymphoma and Hodgkin disease cells. Blood 2000, 96(13): 4307-12.
-
(2000)
Blood
, vol.96
, Issue.13
, pp. 4307-4312
-
-
Mir, S.S.1
Richter, B.W.2
Duckett, C.S.3
-
22
-
-
84878726626
-
Combination of the anti-CD30-auristatin-E antibody-drug conjugate SGN-35 with chemotherapy improves antitumor activity in Hodgkin's lymphoma
-
10th Int Conf Malig Lymphoma (June 4-7, Lugano) 2008 Abst 529
-
Oflazoglu, E., Kennedy, D., Sievers, E.L. et al. Combination of the anti-CD30-auristatin-E antibody-drug conjugate SGN-35 with chemotherapy improves antitumor activity in Hodgkin's lymphoma. Ann Oncol [10th Int Conf Malig Lymphoma (June 4-7, Lugano) 2008] 2008, 19(Suppl. 4): Abst 529.
-
(2008)
Ann Oncol
, vol.19
, Issue.SUPPL. 4
-
-
Oflazoglu, E.1
Kennedy, D.2
Sievers, E.L.3
-
23
-
-
44649184200
-
Combination of the anti-CD30-auristatin-E antibody-drug conjugate (SGN-35) with chemotherapy improves antitumour activity in Hodgkin lymphoma
-
DOI 10.1111/j.1365-2141.2008.07146.x
-
Oflazoglu, E., Kissler, K.M., Sievers, E.L., Grewal, I.S., Gerber, H.P. Combination of the anti-CD30-auristatin-E antibody-drug conjugate (SGN-35) with chemotherapy improves antitumour activity in Hodgkin lymphoma. Br J Haematol 2008, 142(1): 69-73. (Pubitemid 351783148)
-
(2008)
British Journal of Haematology
, vol.142
, Issue.1
, pp. 69-73
-
-
Oflazoglu, E.1
Kissler, K.M.2
Sievers, E.L.3
Grewal, I.S.4
Gerber, H.-P.5
-
24
-
-
23044452477
-
Randomized comparison of ABVD chemotherapy with a strategy that includes radiation therapy in patients with limited-stage Hodgkin's lymphoma: National Cancer Institute of Canada Clinical Trials Group and the Eastern Cooperative Oncology Group
-
DOI 10.1200/JCO.2005.09.085
-
Meyer, R.M., Gospodarowicz, M.K., Connors, J.M. et al. Randomized comparison of ABVD chemotherapy with a strategy that includes radiation therapy in patients with limited- stage Hodgkin's lymphoma: National Cancer Institute of Canada Clinical Trials Group and the Eastern Cooperative Oncology Group. J Clin Oncol 2005, 23(21): 4634-42. (Pubitemid 46237440)
-
(2005)
Journal of Clinical Oncology
, vol.23
, Issue.21
, pp. 4634-4642
-
-
Meyer, R.M.1
Gospodarowicz, M.K.2
Connors, J.M.3
Pearcey, R.G.4
Bezjak, A.5
Wells, W.A.6
Burns, B.F.7
Winter, J.N.8
Horning, S.J.9
Dar, A.R.10
Djurfeldt, M.S.11
Ding, K.12
Shepherd, L.E.13
-
25
-
-
59449100987
-
Defining a population of Hodgkin lymphoma patients for novel therapeutics: An international effort
-
10th Int Conf Malig Lymphoma (June 4-7, Lugano) 2008
-
Horning, S., Fanale, M., deVos, S. et al. Defining a population of Hodgkin lymphoma patients for novel therapeutics: An international effort. Ann Oncol [10th Int Conf Malig Lymphoma (June 4-7, Lugano) 2008] 2008, 19(Suppl. 4): 120-1.
-
(2008)
Ann Oncol
, vol.19
, Issue.SUPPL. 4
, pp. 120-121
-
-
Horning, S.1
Fanale, M.2
DeVos, S.3
-
26
-
-
33847047457
-
Salvage therapy in Hodgkin's lymphoma
-
Byrne, B.J., Gockerman, J.P. Salvage therapy in Hodgkin's lymphoma. Oncologist 2007, 12(2): 156-67.
-
(2007)
Oncologist
, vol.12
, Issue.2
, pp. 156-167
-
-
Byrne, B.J.1
Gockerman, J.P.2
-
27
-
-
77649160262
-
Single-drug vinblastine as salvage treatment for refractory or relapsed anaplastic large-cell lymphoma: A report from the French Society of Pediatric Oncology
-
Brugieres, L., Pacquement, H., Le Deley, M.C. et al. Single-drug vinblastine as salvage treatment for refractory or relapsed anaplastic large-cell lymphoma: a report from the French Society of Pediatric Oncology. J Clin Oncol 2009, 27(30): 5056-61.
-
(2009)
J Clin Oncol
, vol.27
, Issue.30
, pp. 5056-5061
-
-
Brugieres, L.1
Pacquement, H.2
Le Deley, M.C.3
-
28
-
-
0036891149
-
Trofosfamide as salvage therapy for anaplastic large cell lymphoma relapsing after high-dose chemotherapy
-
DOI 10.1080/1042819021000040053
-
Andersson, P.O., Braide, I., Nilsson-Ehle, H. Trofosfamide as salvage therapy for anaplastic large cell lymphoma relapsing after high-dose chemotherapy. Leuk Lymphoma 2002, 43(12): 2351-3. (Pubitemid 35386158)
-
(2002)
Leukemia and Lymphoma
, vol.43
, Issue.12
, pp. 2351-2353
-
-
Andersson, P.O.1
Braide, I.2
Hilsson-Ehle, H.3
-
29
-
-
79951976403
-
Crizotinib in anaplastic large-cell lymphoma
-
Gambacorti-Passerini, C., Messa, C., Pogliani, E.M. Crizotinib in anaplastic large-cell lymphoma. N Engl J Med 2011, 364(8): 775-6.
-
(2011)
N Engl J Med
, vol.364
, Issue.8
, pp. 775-776
-
-
Gambacorti-Passerini, C.1
Messa, C.2
Pogliani, E.M.3
-
30
-
-
1842483136
-
High-dose therapy and autologous stem cell transplant does not result in long-term disease-free survival in patients with reccurent chemotherapy- sensitive ALK-negative anaplastic large-cell lymphoma
-
DOI 10.1038/sj.bmt.1704392
-
Zamkoff, K.W., Matulis, M.D., Mehta, A.C., Beaty, M.W., Hutchison, R.E., Gentile, T.C. High-dose therapy and autologous stem cell transplant does not result in long-term disease- free survival in patients with recurrent chemotherapy-sensitive ALK-negative anaplastic large-cell lymphoma. Bone Marrow Transplant 2004, 33(6): 635-8. (Pubitemid 38455926)
-
(2004)
Bone Marrow Transplantation
, vol.33
, Issue.6
, pp. 635-638
-
-
Zamkoff, K.W.1
Matulis, M.D.2
Mehta, A.C.3
Beaty, M.W.4
Hutchison, R.E.5
Gentile, T.C.6
-
31
-
-
0035557909
-
Rituximab: Review and clinical applications focusing on non-Hodgkin's lymphoma
-
King, K.M., Younes, A. Rituximab: review and clinical applications focusing on non-Hodgkin's lymphoma. Expert Rev Anticancer Ther 2001, 1(2): 177-86. (Pubitemid 34679409)
-
(2001)
Expert Review of Anticancer Therapy
, vol.1
, Issue.2
, pp. 177-186
-
-
King, K.M.1
Younes, A.2
-
32
-
-
0026774327
-
In vivo targeting of Hodgkin and Reed-Sternberg cells of Hodgkin's disease with monoclonal antibody Ber-H2 (CD30): Immunohistological evidence
-
Falini, B., Flenghi, L., Fedeli, L. et al. In vivo targeting of Hodgkin and Reed-Sternberg cells of Hodgkin's disease with monoclonal antibody Ber-H2 (CD30): immunohistological evidence. Br J Haematol 1992, 82(1): 38-45.
-
(1992)
Br J Haematol
, vol.82
, Issue.1
, pp. 38-45
-
-
Falini, B.1
Flenghi, L.2
Fedeli, L.3
-
33
-
-
41349086204
-
+ hematologic malignancies
-
DOI 10.1182/blood-2007-07-099317
-
Bartlett, N.L., Younes, A., Carabasi, M.H. et al. A phase 1 multidose study of SGN-30 immunotherapy in patients with refractory or recurrent CD30+ hematologic malignancies. Blood 2008, 111(4): 1848-54. (Pubitemid 351451492)
-
(2008)
Blood
, vol.111
, Issue.4
, pp. 1848-1854
-
-
Bartlett, N.L.1
Younes, A.2
Carabasi, M.H.3
Forero, A.4
Rosenblatt, J.D.5
Leonard, J.P.6
Bernstein, S.H.7
Bociek, R.G.8
Lorenz, J.M.9
Hart, B.W.10
Barton, J.11
-
34
-
-
0036645267
-
The anti-CD30 monoclonal antibody SGN-30 promotes growth arrest and DNA fragmentation in Vitro and affects antitumor activity in models of Hodgkin's disease
-
Wahl, A.F., Klussman, K., Thompson, J.D. et al. The anti- CD30 monoclonal antibody SGN-30 promotes growth arrest and DNA fragmentation in vitro and affects antitumor activity in models of Hodgkin's disease. Cancer Res 2002, 62(13): 3736-42. (Pubitemid 34728855)
-
(2002)
Cancer Research
, vol.62
, Issue.13
, pp. 3736-3742
-
-
Wahl, A.F.1
Klussman, K.2
Thompson, J.D.3
Chen, J.H.4
Francisco, L.V.5
Risdon, G.6
Chace, D.F.7
Siegall, C.B.8
Francisco, J.A.9
-
35
-
-
34447573999
-
Phase I/II study of an anti-CD30 monoclonal antibody (MDX-060) in Hodgkin's lymphoma and anaplastic large-cell lymphoma
-
DOI 10.1200/JCO.2006.07.8972
-
Ansell, S.M., Horwitz, S.M., Engert, A. et al. Phase I/II study of an anti-CD30 monoclonal antibody (MDX-060) in Hodgkin's lymphoma and anaplastic large-cell lymphoma. J Clin Oncol 2007, 25(19): 2764-9. (Pubitemid 47123185)
-
(2007)
Journal of Clinical Oncology
, vol.25
, Issue.19
, pp. 2764-2769
-
-
Ansell, S.M.1
Horwitz, S.M.2
Engert, A.3
Khan, K.D.4
Lin, T.5
Strair, R.6
Keler, T.7
Graziano, R.8
Blanset, D.9
Yellin, M.10
Fischkoff, S.11
Assad, A.12
Borchmann, P.13
-
36
-
-
80054113954
-
Antibody-drug conjugates of calicheamicin derivative: Gemtuzumab ozogamicin and inotuzumab ozogamicin
-
Ricart, A.D. Antibody-drug conjugates of calicheamicin derivative: gemtuzumab ozogamicin and inotuzumab ozogamicin. Clin Cancer Res 2011, 17(20): 6417-27.
-
(2011)
Clin Cancer Res
, vol.17
, Issue.20
, pp. 6417-6427
-
-
Ricart, A.D.1
-
37
-
-
77955312203
-
Antibody-drug conjugates: Targeted drug delivery for cancer
-
Alley, S.C., Okeley, N.M., Senter, P.D. Antibody-drug conjugates: targeted drug delivery for cancer. Curr Opin Chem Biol 2010, 14(4): 529-37.
-
(2010)
Curr Opin Chem Biol
, vol.14
, Issue.4
, pp. 529-537
-
-
Alley, S.C.1
Okeley, N.M.2
Senter, P.D.3
-
38
-
-
84860705112
-
SGN-35, an anti-CD30 antibody-drug conjugate with potent antitumor activity
-
94th Annu Meet Am Assoc Cancer Res (AACR) (July 10-14, Washington, D.C.) 2003 (2nd Ed.): Abst R770
-
Francisco, J.A., Cerveny, C.G., Meyer, D.L., Siegall, C., Senter, P.D., Wahl, A.F. SGN-35, an anti-CD30 antibody-drug conjugate with potent antitumor activity. Proc Am Assoc Cancer Res [94th Annu Meet Am Assoc Cancer Res (AACR) (July 10-14, Washington, D.C.) 2003] 2003, 44(2nd Ed.): Abst R770.
-
(2003)
Proc Am Assoc Cancer Res
, vol.44
-
-
Francisco, J.A.1
Cerveny, C.G.2
Meyer, D.L.3
Siegall, C.4
Senter, P.D.5
Wahl, A.F.6
-
39
-
-
0042738861
-
cAC10-vcMMAE, an anti-CD30-monomethyl auristatin E conjugate with potent and selective antitumor activity
-
DOI 10.1182/blood-2003-01-0039
-
Francisco, J.A., Cerveny, C.G., Meyer, D.L. et al. cAC10- vcMMAE, an anti-CD30-monomethyl auristatin E conjugate with potent and selective antitumor activity. Blood 2003, 102(4): 1458-65. (Pubitemid 36988057)
-
(2003)
Blood
, vol.102
, Issue.4
, pp. 1458-1465
-
-
Francisco, J.A.1
Cerveny, C.G.2
Meyer, D.L.3
Mixan, B.J.4
Klussman, K.5
Chace, D.F.6
Rejniak, S.X.7
Gordon, K.A.8
DeBlanc, R.9
Toki, B.E.10
Law, C.-L.11
Doronina, S.O.12
Siegall, C.B.13
Senter, P.D.14
Wahl, A.F.15
-
40
-
-
84878734052
-
Potent monoclonal antibody drug conjugates: The role of linker stability in efficacy, toxicity, and specificity
-
94th Annu Meet Am Assoc Cancer Res (AACR) (July 10-14, Washington, D.C.) 2003 (2nd Ed.): Abst 6425
-
Senter, P., Doronina, S., Toki, B. et al. Potent monoclonal antibody drug conjugates: The role of linker stability in efficacy, toxicity, and specificity. Proc Am Assoc Cancer Res [94th Annu Meet Am Assoc Cancer Res (AACR) (July 10-14, Washington, D.C.) 2003] 2003, 44(2nd Ed.): Abst 6425.
-
(2003)
Proc Am Assoc Cancer Res
, vol.44
-
-
Senter, P.1
Doronina, S.2
Toki, B.3
-
41
-
-
10744222473
-
Development of potent monoclonal antibody auristatin conjugates for cancer therapy
-
DOI 10.1038/nbt832
-
Doronina, S.O., Toki, B.E., Torgov, M.Y. et al. Development of potent monoclonal antibody auristatin conjugates for cancer therapy. Nat Biotechnol 2003, 21(7): 778-84. (Pubitemid 36791396)
-
(2003)
Nature Biotechnology
, vol.21
, Issue.7
, pp. 778-784
-
-
Doronina, S.O.1
Toki, B.E.2
Torgov, M.Y.3
Mendelsohn, B.A.4
Cerveny, C.G.5
Chace, D.F.6
DeBlanc, R.L.7
Gearing, R.P.8
Bovee, T.D.9
Siegall, C.B.10
Francisco, J.A.11
Wahl, A.F.12
Meyer, D.L.13
Senter, P.D.14
-
42
-
-
76049122850
-
Intracellular activation of SGN-35, a potent anti-CD30 antibody-drug conjugate
-
Okeley, N.M., Miyamoto, J.B., Zhang, X. et al. Intracellular activation of SGN-35, a potent anti-CD30 antibody-drug conjugate. Clin Cancer Res 2010, 16(3): 888-97.
-
(2010)
Clin Cancer Res
, vol.16
, Issue.3
, pp. 888-897
-
-
Okeley, N.M.1
Miyamoto, J.B.2
Zhang, X.3
-
43
-
-
80054117546
-
Brentuximab Vedotin (SGN-35)
-
Katz, J., Janik, J.E., Younes, A. Brentuximab Vedotin (SGN-35). Clin Cancer Res 2011, 17(20): 6428-36.
-
(2011)
Clin Cancer Res
, vol.17
, Issue.20
, pp. 6428-6436
-
-
Katz, J.1
Janik, J.E.2
Younes, A.3
-
44
-
-
84878735096
-
Specific tumor targeting and potent bystander killing with SGN-35, an anti-CD30 antibody drug conjugate
-
48th Annu Meet Am Soc Hematol (Dec 9-12, Orlando) 2006 Abst 231
-
Okeley, N.M., Alley, S.C., Cerveny, C.G. et al. Specific tumor targeting and potent bystander killing with SGN-35, an anti-CD30 antibody drug conjugate. Blood [48th Annu Meet Am Soc Hematol (Dec 9-12, Orlando) 2006] 2006, 108(11): Abst 231.
-
(2006)
Blood
, vol.108
, Issue.11
-
-
Okeley, N.M.1
Alley, S.C.2
Cerveny, C.G.3
-
45
-
-
78049515807
-
Brentuximab vedotin (SGN-35) for relapsed CD30-positive lymphomas
-
Younes, A., Bartlett, N.L., Leonard, J.P., Kennedy, D.A., Lynch, C.M., Sievers, E.L., Forero-Torres, A. Brentuximab vedotin (SGN-35) for relapsed CD30-positive lymphomas. N Engl J Med 2010, 363(19): 1812-21.
-
(2010)
N Engl J Med
, vol.363
, Issue.19
, pp. 1812-1821
-
-
Younes, A.1
Bartlett, N.L.2
Leonard, J.P.3
Kennedy, D.A.4
Lynch, C.M.5
Sievers, E.L.6
Forero-Torres, A.7
-
46
-
-
33748106649
-
SGN-35, an anti-CD30 antibody-drug conjugate, exhibits potent antitumor activity for the treatment of CD30(+) malignancies
-
47th Annu Meet Am Soc Hematol (Dec 10-13 Atlanta) 2005 Abst 610
-
Hamblett, K.J., Barton, J., Cerveny, C.G. et al. SGN-35, an anti-CD30 antibody-drug conjugate, exhibits potent antitumor activity for the treatment of CD30(+) malignancies. Blood [47th Annu Meet Am Soc Hematol (Dec 10-13 Atlanta) 2005] 2005, 106(11): Abst 610.
-
(2005)
Blood
, vol.106
, Issue.11
-
-
Hamblett, K.J.1
Barton, J.2
Cerveny, C.G.3
-
47
-
-
85016165194
-
Effect of drug loading on the pharmacology, pharmacokinetics, and toxicity of an anti-CD30 antibody-drug conjugate
-
95th Annu Meet Am Assoc Cancer Res (AACR) (March 27-31, Orlando) 2004 Abst 624
-
Hamblett, K.J., Meyer, D.L., Chace, D.F. et al. Effect of drug loading on the pharmacology, pharmacokinetics, and toxicity of an anti-CD30 antibody-drug conjugate. Proc Am Assoc Cancer Res [95th Annu Meet Am Assoc Cancer Res (AACR) (March 27-31, Orlando) 2004] 2004, 45: Abst 624.
-
(2004)
Proc Am Assoc Cancer Res
, vol.45
-
-
Hamblett, K.J.1
Meyer, D.L.2
Chace, D.F.3
-
48
-
-
6044223544
-
Effects of drug loading on the antitumor activity of a monoclonal antibody drug conjugate
-
DOI 10.1158/1078-0432.CCR-04-0789
-
Hamblett, K.J., Senter, P.D., Chace, D.F. et al. Effects of drug loading on the antitumor activity of a monoclonal antibody drug conjugate. Clin Cancer Res 2004, 10(20): 7063-70. (Pubitemid 39383058)
-
(2004)
Clinical Cancer Research
, vol.10
, Issue.20
, pp. 7063-7070
-
-
Hamblett, K.J.1
Senter, P.D.2
Chace, D.F.3
Sun, M.M.C.4
Lenox, J.5
Cerveny, C.G.6
Kissler, K.M.7
Bernhardt, S.X.8
Kopcha, A.K.9
Zabinski, R.F.10
Meyer, D.L.11
Francisco, J.A.12
-
49
-
-
12244295755
-
In vivo drug-linker stability of an anti-CD30 dipeptide-linked auristatin immunoconjugate
-
Sanderson, R.J., Hering, M.A., James, S.F. et al. In vivo druglinker stability of an anti-CD30 dipeptide-linked auristatin immunoconjugate. Clin Cancer Res 2005, 11(2 Pt 1): 843-52. (Pubitemid 40116913)
-
(2005)
Clinical Cancer Research
, vol.11
, Issue.2 I
, pp. 843-852
-
-
Sanderson, R.J.1
Hering, M.A.2
James, S.F.3
Sun, M.M.C.4
Doronina, S.O.5
Siadak, A.W.6
Senter, P.D.7
Wahl, A.F.8
-
50
-
-
84860703420
-
Effective tumor targeting by auristatin antibody-drug conjugates
-
Abst 4088
-
Alley, S.C., Kissler, K., Morris-Tilden, C., Miyamoto, J., Senter, P.D., Benjamin, D.R. Effective tumor targeting by auristatin antibody-drug conjugates. Proc Am Assoc Cancer Res (AACR) 2007, 48: Abst 4088.
-
(2007)
Proc Am Assoc Cancer Res (AACR)
, vol.48
-
-
Alley, S.C.1
Kissler, K.2
Morris-Tilden, C.3
Miyamoto, J.4
Senter, P.D.5
Benjamin, D.R.6
-
52
-
-
53049084469
-
A novel antibody- drug conjugate, SGN-35 (anti-CD30-auristatin), induces objective responses in patients with relapsed or refractory Hodgkin lymphoma: Preliminary results of a phase I tolerability study
-
7th Int Symp Hodgkin Lymphoma (Nov 3-7, Cologne) 2007 Abst P099bis
-
Younes, A., Forero-Torres, A., Bartlett, N. et al. A novel antibody- drug conjugate, SGN-35 (anti-CD30-auristatin), induces objective responses in patients with relapsed or refractory Hodgkin lymphoma: Preliminary results of a phase I tolerability study. Haematologica [7th Int Symp Hodgkin Lymphoma (Nov 3-7, Cologne) 2007] 2007, 92(Suppl. 5): Abst P099bis.
-
(2007)
Haematologica
, vol.92
, Issue.SUPPL. 5
-
-
Younes, A.1
Forero-Torres, A.2
Bartlett, N.3
-
53
-
-
66249142404
-
Multiple complete responses in a phase I dose-escalation study of the antibody-drug conjugate SGN-35 in patients with relapsed or refractory CD30-positive lymphomas
-
50th Annu Meet Am Soc Hematol (Dec 6-9, San Francisco) 2008 Abst 1006
-
Younes, A., Forero-Torres, A., Bartlett, N.L., Leonard, J.P., Lynch, C., Kennedy, D.A., Sievers, E. Multiple complete responses in a phase I dose-escalation study of the antibody-drug conjugate SGN-35 in patients with relapsed or refractory CD30-positive lymphomas. Blood [50th Annu Meet Am Soc Hematol (Dec 6-9, San Francisco) 2008] 2008, 112(11): Abst 1006.
-
(2008)
Blood
, vol.112
, Issue.11
-
-
Younes, A.1
Forero-Torres, A.2
Bartlett, N.L.3
Leonard, J.P.4
Lynch, C.5
Kennedy, D.A.6
Sievers, E.7
-
54
-
-
53349093644
-
Objective responses in a phase I dose-escalation study of SGN-35, a novel antibody-drug conjugate (ADC) targeting CD30, in patients with relapsed or refractory Hodgkin lymphoma
-
10th Int Conf Malig Lymphoma (June 4-7, Lugano) 2008 Abst 141
-
Younes, A., Forero-Torres, A., Bartlett, N.L. et al. Objective responses in a phase I dose-escalation study of SGN-35, a novel antibody-drug conjugate (ADC) targeting CD30, in patients with relapsed or refractory Hodgkin lymphoma. Ann Oncol [10th Int Conf Malig Lymphoma (June 4-7, Lugano) 2008] 2008, 19(Suppl. 4): Abst 141.
-
(2008)
Ann Oncol
, vol.19
, Issue.SUPPL. 4
-
-
Younes, A.1
Forero-Torres, A.2
Bartlett, N.L.3
-
55
-
-
53349093644
-
Objective responses in a phase I dose-escalation study of SGN-35, a novel antibody-drug conjugate (ADC) targeting CD30, in patients with relapsed or refractory Hodgkin lymphoma
-
44th Annu Meet Am Soc Clin Oncol (ASCO) (May 30-June 3, Chicago) 2008 Abst 8526
-
Younes, A., Forero-Torres, A., Bartlett, N.L. et al. Objective responses in a phase I dose-escalation study of SGN-35, a novel antibody-drug conjugate (ADC) targeting CD30, in patients with relapsed or refractory Hodgkin lymphoma. J Clin Oncol [44th Annu Meet Am Soc Clin Oncol (ASCO) (May 30-June 3, Chicago) 2008] 2008, 26(15, Suppl.): Abst 8526.
-
(2008)
J Clin Oncol
, vol.26
, Issue.15 SUPPL.
-
-
Younes, A.1
Forero-Torres, A.2
Bartlett, N.L.3
-
56
-
-
70349645606
-
Robust antitumor activity of the antibody-drug conjugate SGN-35 when administered every 3 weeks to patients with relapsed or refractory CD30 positive hematologic malignancies in a phase 1 study
-
14th Congr Eur Hematol Assoc (EHA) (June 4-7, Berlin) 2009 Abst 0503
-
Younes, A., Forero-Torres, A., Bartlett, N.L., Leonard, J.P., Kennedy, D.A., Sievers, E.L. Robust antitumor activity of the antibody-drug conjugate SGN-35 when administered every 3 weeks to patients with relapsed or refractory CD30 positive hematologic malignancies in a phase 1 study. Haematologica [14th Congr Eur Hematol Assoc (EHA) (June 4-7, Berlin) 2009] 2009, 94: Abst 0503.
-
(2009)
Haematologica
, vol.94
-
-
Younes, A.1
Forero-Torres, A.2
Bartlett, N.L.3
Leonard, J.P.4
Kennedy, D.A.5
Sievers, E.L.6
-
57
-
-
70349645442
-
Complete remissions with weekly dosing of SGN-35, a novel antibody-drug conjugate (ADC) targeting CD30, in a phase I dose-escalation study in patients with relapsed or refractory Hodgkin lymphoma (HL) or systemic anaplastic large cell lymphoma (sALCL)
-
45th Annu Meet Am Soc Clin Oncol (ASCO) (May 29-June 2, Orlando) 2009 Abst 8500
-
Bartlett, N., Forero-Torres, A., Rosenblatt, J. et al. Complete remissions with weekly dosing of SGN-35, a novel antibody-drug conjugate (ADC) targeting CD30, in a phase I dose-escalation study in patients with relapsed or refractory Hodgkin lymphoma (HL) or systemic anaplastic large cell lymphoma (sALCL). J Clin Oncol [45th Annu Meet Am Soc Clin Oncol (ASCO) (May 29-June 2, Orlando) 2009] 2009, 27(15, Suppl.): Abst 8500.
-
(2009)
J Clin Oncol
, vol.27
, Issue.15 SUPPL.
-
-
Bartlett, N.1
Forero-Torres, A.2
Rosenblatt, J.3
-
58
-
-
77955311034
-
The antibody- drug conjugate brentuximab vedotin (SGN-35) induced multiple objective responses in patients with relapsed or refractory CD30-positive lymphomas in a phase 1 weekly dosing study
-
51st Annu Meet Am Soc Hematol (Dec 5-8, New Orleans) 2009 Abst 2731
-
Fanale, M., Bartlett, N.L., Forero-Torres, A. et al. The antibody- drug conjugate brentuximab vedotin (SGN-35) induced multiple objective responses in patients with relapsed or refractory CD30-positive lymphomas in a phase 1 weekly dosing study. Blood [51st Annu Meet Am Soc Hematol (Dec 5-8, New Orleans) 2009] 2009, 114(22): Abst 2731.
-
(2009)
Blood
, vol.114
, Issue.22
-
-
Fanale, M.1
Bartlett, N.L.2
Forero-Torres, A.3
-
59
-
-
84855465227
-
A phase I weekly dosing study of brentuximab vedotin in patients with relapsed/refractory CD30-positive hematologic malignancies
-
Fanale, M.A., Forero-Torres, A., Rosenblatt, J.D. et al. A phase I weekly dosing study of brentuximab vedotin in patients with relapsed/refractory CD30-positive hematologic malignancies. Clin Cancer Res 2012, 18(1): 248-55.
-
(2012)
Clin Cancer Res
, vol.18
, Issue.1
, pp. 248-255
-
-
Fanale, M.A.1
Forero-Torres, A.2
Rosenblatt, J.D.3
-
60
-
-
84878686424
-
Complete remissions observed in a subset of pediatric patients with CD30-expressing malignant lymphomas treated in clinical studies of brentuximab vedotin (SGN-35)
-
Abst 9201
-
Fanale, M., Franklin, A., Radhakrishnan, R. et al. Complete remissions observed in a subset of pediatric patients with CD30-expressing malignant lymphomas treated in clinical studies of brentuximab vedotin (SGN-35). Eur J Cancer 2011, 47(Suppl. 1): Abst 9201.
-
(2011)
Eur J Cancer
, vol.47
, Issue.SUPPL. 1
-
-
Fanale, M.1
Franklin, A.2
Radhakrishnan, R.3
-
61
-
-
84878699013
-
Objective responses with brentuximab vedotin (SGN-35) retreatment in CD30-positive hematologic malignancies: A case series
-
Abst 8062
-
Bartlett, N., Grove, L.E., Kennedy, D.A., Sievers, E.L., Forero- Torres, A. Objective responses with brentuximab vedotin (SGN-35) retreatment in CD30-positive hematologic malignancies: A case series. 46th Annu Meet Am Soc Clin Oncol (ASCO) (June 4-8, Chicago) 2010, Abst 8062.
-
46th Annu Meet Am Soc Clin Oncol (ASCO) (June 4-8, Chicago) 2010
-
-
Bartlett, N.1
Grove, L.E.2
Kennedy, D.A.3
Sievers, E.L.4
Forero-Torres, A.5
-
62
-
-
84878738758
-
Objective responses with brentuximab vedotin (SGN-35) in patients with relapsed or refractory Hodgkin lymphoma (HL) who refused or were ineligible for Autologous Stem Cell Transplantation (ASCT)
-
Abst 0518
-
Advani, R., Forero-Torres, A., Fanale, M. et al. Objective responses with brentuximab vedotin (SGN-35) in patients with relapsed or refractory Hodgkin lymphoma (HL) who refused or were ineligible for Autologous Stem Cell Transplantation (ASCT). 16th Congr Eur Hematol Assoc (EHA) (June 9-12, London) 2011, Abst 0518.
-
16th Congr Eur Hematol Assoc (EHA) (June 9-12, London) 2011
-
-
Advani, R.1
Forero-Torres, A.2
Fanale, M.3
-
70
-
-
84857019891
-
Preclinical and clinical binding properties, internalization kinetics, and clinicopathological activity of brentuximab vedotin (SGN-35): Novel antibody drug conjugate for anaplastic large cell lymphoma and classical Hodgkin lymphoma
-
52nd Annu Meet Am Soc Hematol (Dec 4-7, Orlando) 2010 Abst 1789
-
Fromm, J.R., McEarchern, J.A., Kennedy, D., Anju, T., Shustov, A.R., Gopal, A.K. Preclinical and clinical binding properties, internalization kinetics, and clinicopathological activity of brentuximab vedotin (SGN-35): Novel antibody drug conjugate for anaplastic large cell lymphoma and classical Hodgkin lymphoma. Blood [52nd Annu Meet Am Soc Hematol (Dec 4-7, Orlando) 2010] 2010, 116(21): Abst 1789.
-
(2010)
Blood
, vol.116
, Issue.21
-
-
Fromm, J.R.1
McEarchern, J.A.2
Kennedy, D.3
Anju, T.4
Shustov, A.R.5
Gopal, A.K.6
-
72
-
-
78951477856
-
Results of a pivotal phase 2 study of brentuximab vedotin (SGN 35) in patients with relapsed or refractory Hodgkin lymphoma
-
52nd Annu Meet Am Soc Hematol (Dec 4-7, Orlando) 2010 Abst 283
-
Chen, R., Gopal, A.K., Smith, S.E. et al. Results of a pivotal phase 2 study of brentuximab vedotin (SGN 35) in patients with relapsed or refractory Hodgkin lymphoma Blood [52nd Annu Meet Am Soc Hematol (Dec 4-7, Orlando) 2010] 2010, 116(21): Abst 283.
-
(2010)
Blood
, vol.116
, Issue.21
-
-
Chen, R.1
Gopal, A.K.2
Smith, S.E.3
-
73
-
-
84878734463
-
SGN-35, an anti- CD30 antibody-drug conjugate, exhibits potent antitumor activity for the treatment of CD30(+) malignancies
-
Abst 8031
-
Chen, R.W., Gopal, A.K., Smith, S.E. et al. SGN-35, an anti- CD30 antibody-drug conjugate, exhibits potent antitumor activity for the treatment of CD30(+) malignancies. 47th Annu Meet Am Soc Clin Oncol (ASCO) (June 3-7, Chicago) 2011, Abst 8031.
-
47th Annu Meet Am Soc Clin Oncol (ASCO) (June 3-7, Chicago) 2011
-
-
Chen, R.W.1
Gopal, A.K.2
Smith, S.E.3
-
75
-
-
78951471865
-
Complete remissions with brentuximab vedotin (SGN-35) in patients with relapsed or refractory systemic anaplastic large cell lymphoma
-
52nd Annu Meet Am Soc Hematol (Dec 4-7, Orlando) 2010 Abst 961
-
Shustov, A.R., Advani, R., Brice, P. et al. Complete remissions with brentuximab vedotin (SGN-35) in patients with relapsed or refractory systemic anaplastic large cell lymphoma. Blood [52nd Annu Meet Am Soc Hematol (Dec 4-7, Orlando) 2010] 2010, 116(21): Abst 961.
-
(2010)
Blood
, vol.116
, Issue.21
-
-
Shustov, A.R.1
Advani, R.2
Brice, P.3
-
77
-
-
84878693339
-
Resolution of malignant cutaneous lesions with brentuximab vedotin (SGN-35) in patients with relapsed or refractory systemic anaplastic large cell lymphoma
-
Abst 0369
-
Advani, R., Fanale, M., Brice, P. et al. Resolution of malignant cutaneous lesions with brentuximab vedotin (SGN-35) in patients with relapsed or refractory systemic anaplastic large cell lymphoma. 16th Congr Eur Hematol Assoc (EHA) (June 9-12, London) 2011, Abst 0369
-
16th Congr Eur Hematol Assoc (EHA) (June 9-12, London) 2011
-
-
Advani, R.1
Fanale, M.2
Brice, P.3
-
78
-
-
84878733271
-
Durable remissions with brentuximab vedotin (SGN-035): Updated results of a phase II study in patients with relapsed or refractory systemic anaplastic large cell lymphoma (sALCL)
-
Abst 8032
-
Pro, B., Advani, R., Brice, P. et al. Durable remissions with brentuximab vedotin (SGN-035): Updated results of a phase II study in patients with relapsed or refractory systemic anaplastic large cell lymphoma (sALCL). 47th Annu Meet Am Soc Clin Oncol (ASCO) (June 3-7, Chicago) 2011, Abst 8032.
-
47th Annu Meet Am Soc Clin Oncol (ASCO) (June 3-7, Chicago) 2011
-
-
Pro, B.1
Advani, R.2
Brice, P.3
-
79
-
-
84878744170
-
Brentuximab vedotin (SGN-35) treatment in relapsed CD30- Positive Hodgkin's lymphoma patients following allogeneic stem cell transplant: A multi-centre case series
-
Abst O267
-
Gopal, A.K., Ramchandren, R., Berryman, R.B. et al. Brentuximab vedotin (SGN-35) treatment in relapsed CD30- positive Hodgkin's lymphoma patients following allogeneic stem cell transplant: a multi-centre case series. Bone Marrow Transplant 2011, 46(Suppl. 1): Abst O267.
-
(2011)
Bone Marrow Transplant
, vol.46
, Issue.SUPPL. 1
-
-
Gopal, A.K.1
Ramchandren, R.2
Berryman, R.B.3
-
87
-
-
84878735827
-
-
Accessed February 27, 2012
-
Seattle Genetics pipeline. http://www.seagen.com/product-pipeline-sgn35. shtml. Accessed February 27, 2012.
-
Seattle Genetics Pipeline
-
-
-
88
-
-
84878711046
-
-
Accessed February 27, 2012
-
Seattle Genetics products. http://www.seagen.com/product-adcetris.shtml Accessed February 27, 2012.
-
Seattle Genetics Products
-
-
|