Microsatellite markers within the α-globin gene cluster for robust preimplantation genetic diagnosis of severe α-Thalassemia syndromes in mediterranean populations

Hemoglobin

Volumn 36, Issue 3, 2012, Pages 253-264

  Destouni, Aspasia ^a,b   Christopoulos, George ^c   Vrettou, Christina ^a   Kakourou, Georgia ^a   Kleanthous, Marina ^c   Traeger Synodinos, Jan ^a   Kanavakis, Emmanuel ^a,b  

^a UNIVERSITY OF ATHENS   (Greece)

^b Haemophilia Haemostasis Unit   (Greece)

^c CYPRUS INSTITUTE OF NEUROLOGY AND GENETICS   (Cyprus)

Author keywords

Thalassemia ( thal); Hb Bart's Hydrops Fetalis; Hb H disease; Microsatellite repeats; Preimplantation genetic diagnosis (PGD)

Indexed keywords

ALPHA GLOBULIN; PRIMER DNA;

ALLELE; ALPHA THALASSEMIA; ARTICLE; BLASTOMERE; CASE REPORT; CHORION VILLUS SAMPLING; COMPUTER MODEL; EMBRYO; GENE CLUSTER; GENE LOCATION; GENE LOCUS; GENE MUTATION; GENOTYPE; HETEROZYGOSITY; HUMAN; IMPLANTATION; LYMPHOCYTE; MICROSATELLITE MARKER; MOLECULAR DIAGNOSIS; MULTIPLEX LIGATION DEPENDENT PROBE AMPLIFICATION; MULTIPLEX POLYMERASE CHAIN REACTION; NUCLEOTIDE SEQUENCE; POPULATION RESEARCH; PREGNANCY; PRENATAL DIAGNOSIS; PROCESS OPTIMIZATION; SHORT TANDEM REPEAT; SOUTHERN EUROPE; THIRD TRIMESTER PREGNANCY; VALIDATION STUDY;

ALPHA-GLOBINS; ALPHA-THALASSEMIA; CYPRUS; FEMALE; GREECE; HUMANS; MALE; MICROSATELLITE REPEATS; MULTIGENE FAMILY; MULTIPLEX POLYMERASE CHAIN REACTION; PREGNANCY; PREGNANCY COMPLICATIONS, HEMATOLOGIC; PREIMPLANTATION DIAGNOSIS; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; SYNDROME;

EID: 84860729031     PISSN: 03630269     EISSN: 1532432X     Source Type: Journal    
DOI: 10.3109/03630269.2012.666512     Document Type: Article

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