Sustainable release of vancomycin, gentamicin and lidocaine from novel electrospun sandwich-structured PLGA/collagen nanofibrous membranes

International Journal of Pharmaceutics

Volumn 430, Issue 1-2, 2012, Pages 335-341

  Chen, Dave W ^a,b   Hsu, Yung Heng ^a,b   Liao, Jun Yi ^a   Liu, Shih Jung ^a   Chen, Jan Kan ^a   Ueng, Steve Wen Neng ^b  

^a CHANG GUNG UNIVERSITY   (Taiwan)

^b CHANG GUNG MEMORIAL HOSPITAL   (Taiwan)

Author keywords

Cell behavior; Collagen; Electrospinning; Gentamicin; Lidocaine; Nanofibrous membranes; Polylactide polyglycolide (PLGA); Vancomycin

Indexed keywords

COLLAGEN; GENTAMICIN; HEXAFLUORO 2 PROPANOL; LIDOCAINE; NANOFIBER; POLYGLACTIN; VANCOMYCIN;

ARTICLE; CELL ADHESION; CELL SPREADING; DRUG ACTIVITY; DRUG DELIVERY SYSTEM; DRUG RELEASE; DRUG SOLUBILITY; ELECTROSPINNING; FIBROBLAST; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; NONHUMAN; PRIORITY JOURNAL;

ANESTHETICS, LOCAL; ANTI-BACTERIAL AGENTS; CELL ADHESION; CELL SURVIVAL; CELLS, CULTURED; CHEMISTRY, PHARMACEUTICAL; CHILD, PRESCHOOL; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; COLLAGEN; DELAYED-ACTION PREPARATIONS; DISK DIFFUSION ANTIMICROBIAL TESTS; DRUG CARRIERS; DRUG COMPOUNDING; DRUG STABILITY; ESCHERICHIA COLI; FIBROBLASTS; GENTAMICINS; HUMANS; INFANT; KINETICS; LACTIC ACID; LIDOCAINE; MEMBRANES, ARTIFICIAL; MICROBIAL SENSITIVITY TESTS; NANOFIBERS; NANOTECHNOLOGY; POLYGLYCOLIC ACID; PROPANOLS; SOLUBILITY; SOLVENTS; STAPHYLOCOCCUS AUREUS; TECHNOLOGY, PHARMACEUTICAL; VANCOMYCIN;

EID: 84860718111     PISSN: 03785173     EISSN: 18733476     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2012.04.010     Document Type: Article

References (27)

1. S.A.M. Ali, P.J. Doherty, and D.F. Williams Mechanisms of polymer degradation in implantable devices 2. Poly(dl-lactic acid) J. Biomed. Mater. Res. 27 1993 1409 1418 (Pubitemid 23312632)
2. J.P. Chen, G.Y. Chang, and J.K. Chen Electrospun collagen/chitosan nanofibrous membrane as wound dressing Colloids Surf. A: Physiochem. Eng. Aspects 2008 183 188 313-314
3. J.J. Elsner, and M. Zilberman Antibiotic-eluting bioresorbable composite fibers for wound healing applications: microstructures, drug delivery and mechanical properties Acta Biomater. 5 2009 2872 2883
4. J.J. Elsner, D. Egozi, Y. Ullmann, I. Berdicevsky, A. Shefy-Peleg, and M. Zilberman Novel biodegradable composite wound dressings with controlled release of antibiotics: results in guinea pig burn model Burns 37 2011 896 904
5. J. Hansbrough, S. Boyce, M. Cooper, and T. Forman Burn would closure with cultured human keratinocytes and fibroblasts attached to a collagen- glycosaminoglycan substrate J. Am. Med. Assoc. 262 1989 2125 2130 (Pubitemid 20001303)
6. H. Kobayashi, K. Shiraki, and Y. Ikada Toxicity test of biodegradable polymers by implantation in rabbit cornea J. Biomed. Mater. Res. 26 1992 1463 1476
7. K.N. Kontogiannopoulos, A.N. Assimopoulou, I. Tsivintzelis, C. Panayiotou, and V.P. Papageorgiou Electrospun fiber mats containing shikonin and derivatives with potential biomedical applications Int. J. Pharm. 409 2011 216 228
8. S.G. Kumbar, S.P. Nukavarapu, R. James, L.S. Nair, and C.T. Laurencin Electrospun poly(lactic acid-co-glycolic acid) scaffolds for skin tissue engineering Biomaterials 29 2008 4100 4107
9. W.J. Li, C.T. Laurencin, E.J. Caterson, R.S. Tuan, and F.K. Ko Electrospun nanofibrous structure: a novel scaffold for tissue engineering J. Biomed. Mater. Res. 60 2002 613 621 (Pubitemid 34492600)
10. S.J. Liu, Y.C. Kau, C.Y. Chou, J.K. Chen, R.C. Wu, and W.L. Yeh Electrospun PLGA/collagen nanofibrous membrane as early-stage wound dressing J. Membr. Sci. 355 2010 39 53
11. J.A. Matthews, G.E. Wnek, D.G. Simpson, and G.L. Bowlin Electrospinning of collagen nanofibers Biomacromolecules 3 2002 232 238 (Pubitemid 34257140)
12. Z.X. Meng, X.X. Xu, W. Zheng, H.M. Zhou, L. Li, Y.F. Zheng, and X. Lou Preparation and characterization of electrospun PLGA/gelatin nanofibers as a potential drug delivery system Colloids Surf. B: Biointerfaces 84 2011 97 102
13. Z.X. Meng, W. Zheng, L. Li, and Y.F. Zheng Fabrication, characterization and in vitro drug release behavior of electrospun PLGA/chitosan nanofibrous scaffold Mater. Chem. Phys. 125 2011 606 611
14. F.L. Mi, Y.B. Wu, S.S. Shyu, J.Y. Schoung, Y.B. Huang, Y.H. Tsai, and J.Y. Hao Control of wound infections using a bilayer chitosan wound dressing with sustainable antibiotic delivery J. Biomed. Mater. Res. 59 2002 438 449
15. B.M. Min, Y. You, J.M. Kim, S.J. Lee, and W.H. Park Formation of nanostructured poly(lactid-co-glycolid acid)/chitin matrix and its cellular response to normal human keratinocytes and fibroblasts Carbohydr. Polym. 57 2004 285 292
16. H.K. Noh, S.W. Lee, J.M. Kim, J.E. Oh, K.H. Kim, C.P. Chung, S.C. Choi, W.H. Park, and B.M. Min Electrospinning of chitin nanofibers: degradation behavior and cellular response to normal human keratinocytes and fibroblasts Biomaterials 27 2006 3934 3944
17. S.N. Park, H.J. Lee, K.H. Lee, and H. Suh Biological characterization of EDC-crosslinked collagen-hyaluronic acid matrix in dermal tissue restoration Biomaterials 24 2003 1631 1641 (Pubitemid 36143700)
18. D.A.D. Parry, and A.S. Craig Collagen fibril during development and maturation and their contribution to the mechanical attributes of connective tissue M.E. Nimni, Collagen vol. 2 1988 CRC Press Florida 1 20
19. H.M. Powell, D.M. Supp, and S.T. Boyce Influence of electrospun collagen on would contraction of engineered skin substitutes Biomaterials 29 2008 834 843 (Pubitemid 350266048)
20. K.S. Rho, L. Jeong, G. Lee, B.M. Seo, Y.J. Park, S.D. Hong, S. Roh, J.J. Cho, W.H. Park, and B.M. Min Electrospinning of collagen nanofibers: effects on the behavior of normal human keratinocytes and early-stage wound healing Biomaterials 27 2006 1452 1461 (Pubitemid 41739571)
21. T.J. Sill, and H.A. von Recum Electrospinning: applications in drug delivery and tissue engineering Biomaterials 29 2008 1989 2006
22. E.Y. Teo, S.Y. Ong, M.S.K. Chong, Z. Zhang, J. Lu, S. Moochhala, B. Ho, and S.H. Teoh Polycaprolactone-based fused deposition modeled mesh for delivery of antibacterial agents to infected wounds Biomaterials 32 2011 279 287
23. G.D. Warden, J.R. Saffle, and M. Kravitz A 2-stage technique for excision and grafting of burn wounds J. Trauma 22 1982 98 103 (Pubitemid 12132577)
24. D.F. Williams Biodegradation of surgical polymers J. Mater. Sci. 17 1982 1233 1246
25. Y. Yang, X. Zhu, W. Cui, X. Li, and Y. Jin Electrospun composites mats of poly[(d,l-lactide)-co-glycolide] and collagen with high porosity as potential scaffolds for skin tissue engineering Macromol. Mater. Eng. 294 2009 611 619
26. C.R. Yoo, I.S. Yeo, K.E. Park, J.H. Park, S.J. Lee, W.H. Park, and B.M. Min Effect of chitin/silk fibroin nanofibrous bicomponent structures on interaction with human epidermal keratinocytes Int. J. Biol. Macromol. 42 2008 324 334
27. M. Zilberman, and J.J. Elsner Antibiotic-eluting medical devices for various applications J. Control. Release 130 2008 202 215